SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4iri'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IB1_A_IMNA701_1
(LACTOTRANSFERRIN)		 4iri TRANSCRIPTIONAL
REGULATOR ERG
(Homo
sapiens) 		4 / 4 PRO A 327
THR A 325
GLY A 317
THR A 318
 None
 1.13A 3ib1A-4iriA:
undetectable		 3ib1A-4iriA:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KHM_A_TPFA501_1
(STEROL 14
ALPHA-DEMETHYLASE)		 4iri TRANSCRIPTIONAL
REGULATOR ERG
(Homo
sapiens) 		4 / 8 TYR A 371
MET A 361
PHE A 373
LEU A 348
 None
 0.77A 3khmA-4iriA:
undetectable		 3khmA-4iriA:
14.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWW_A_ACAA18_1
(SCRFP-TAG,GP41)		 4iri TRANSCRIPTIONAL
REGULATOR ERG
(Homo
sapiens) 		6 / 12 GLY A 335
GLN A 298
LEU A 300
LEU A 301
GLU A 302
LEU A 303
 None
 0.78A 5nwwA-4iriA:
undetectable		 5nwwA-4iriA:
20.48