SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4irt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQF_A_SAMA430_1
(SUN PROTEIN)		 4irt UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		3 / 3 PRO A 281
ASP A 276
ASP A 303
 None
 0.75A 1sqfA-4irtA:
undetectable		 1sqfA-4irtA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VM1_A_TAZA504_1
(BETA-LACTAMASE SHV-1)		 4irt UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		3 / 3 ASP A 153
TYR A 173
GLU A 100
 None
 0.74A 1vm1A-4irtA:
undetectable		 1vm1A-4irtA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X8V_A_ESLA471_1
(CYTOCHROME P450 51)		 4irt UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		4 / 8 TYR A 197
PHE A  40
ARG A 333
HIS A 110
 None
 1.08A 1x8vA-4irtA:
undetectable		 1x8vA-4irtA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_F_BEZF5023_0
(CES1 PROTEIN)		 4irt UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		5 / 6 LEU A 175
GLY A 152
LEU A 154
ILE A  97
HIS A  48
 None
 1.29A 1yajF-4irtA:
undetectable		 1yajF-4irtA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZGY_A_BRLA503_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 4irt UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		5 / 12 CYH A 117
SER A 106
HIS A 109
LEU A  63
LEU A 114
 None
 1.44A 1zgyA-4irtA:
undetectable		 1zgyA-4irtA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B25_B_SAMB602_0
(HYPOTHETICAL PROTEIN)		 4irt UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		5 / 12 GLY A 161
SER A 162
GLY A 164
ASP A 185
ILE A 186
 None
 1.12A 2b25B-4irtA:
undetectable		 2b25B-4irtA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CL5_B_SAMB1217_1
(CATECHOL
O-METHYLTRANSFERASE)		 4irt UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		4 / 6 GLU A 414
SER A  31
GLN A 418
ASP A  60
 None
 1.40A 2cl5B-4irtA:
undetectable		 2cl5B-4irtA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PRG_B_BRLB2_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 4irt UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		5 / 12 CYH A 117
SER A 106
HIS A 109
LEU A  63
LEU A 114
 None
 1.43A 2prgB-4irtA:
undetectable		 2prgB-4irtA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_B_H3PB552_1
(GLUTAMATE
DEHYDROGENASE)		 4irt UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		3 / 3 TYR A 257
TYR A 246
ILE A 250
 None
 0.83A 3eteA-4irtA:
undetectable
3eteB-4irtA:
undetectable		 3eteA-4irtA:
22.18
3eteB-4irtA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R24_A_SAMA302_1
(2'-O-METHYL
TRANSFERASE)		 4irt UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		3 / 3 TYR A 297
ASP A 373
ASP A 349
 None
 0.82A 3r24A-4irtA:
undetectable		 3r24A-4irtA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_D_SUED1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 4irt UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		4 / 5 PHE A 156
TYR A 173
LEU A 187
ARG A 172
 None
 1.32A 3sudD-4irtA:
undetectable		 3sudD-4irtA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U8Q_A_NPUA7231_1
(LACTOTRANSFERRIN)		 4irt UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		4 / 5 GLY A 279
PRO A 281
ASN A 280
TYR A 282
 None
 1.29A 3u8qA-4irtA:
undetectable		 3u8qA-4irtA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZS3_A_ACTA1227_0
(THAUMATIN-LIKE
PROTEIN)		 4irt UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		4 / 4 THR A 271
ARG A 333
ASN A 223
ILE A 268
 None
 1.41A 3zs3A-4irtA:
0.0		 3zs3A-4irtA:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8F_B_BRLB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4irt UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		5 / 12 CYH A 117
SER A 106
HIS A 109
LEU A  63
LEU A 114
 None
 1.20A 4o8fB-4irtA:
undetectable		 4o8fB-4irtA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_A_URFA302_1
(URIDINE
PHOSPHORYLASE)		 4irt UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		4 / 7 GLY A 407
MET A 328
ALA A 413
ILE A 415
 None
 0.83A 4txnA-4irtA:
undetectable		 4txnA-4irtA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_B_URFB302_1
(URIDINE
PHOSPHORYLASE)		 4irt UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		4 / 7 GLY A 407
MET A 328
ALA A 413
ILE A 415
 None
 0.81A 4txnB-4irtA:
undetectable		 4txnB-4irtA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_C_URFC302_1
(URIDINE
PHOSPHORYLASE)		 4irt UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		4 / 7 GLY A 407
MET A 328
ALA A 413
ILE A 415
 None
 0.79A 4txnC-4irtA:
undetectable		 4txnC-4irtA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_D_URFD302_1
(URIDINE
PHOSPHORYLASE)		 4irt UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		4 / 7 GLY A 407
MET A 328
ALA A 413
ILE A 415
 None
 0.82A 4txnD-4irtA:
undetectable		 4txnD-4irtA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XLD_A_BRLA502_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4irt UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		5 / 12 CYH A 117
SER A 106
HIS A 109
LEU A  63
LEU A 114
 None
 1.27A 4xldA-4irtA:
undetectable		 4xldA-4irtA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHR_B_SAMB303_1
(CATECHOL
O-METHYLTRANSFERASE)		 4irt UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		4 / 5 GLU A 414
SER A  31
GLN A 418
ASP A  60
 None
 1.36A 5fhrB-4irtA:
undetectable		 5fhrB-4irtA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_E_ASCE1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 4irt UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		4 / 7 HIS A  90
ILE A  92
VAL A  35
TYR A  57
 None
 1.12A 5kkzC-4irtA:
undetectable
5kkzE-4irtA:
undetectable		 5kkzC-4irtA:
18.62
5kkzE-4irtA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_K_ASCK1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 4irt UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		4 / 7 HIS A  90
ILE A  92
VAL A  35
TYR A  57
 None
 1.13A 5kkzK-4irtA:
undetectable
5kkzQ-4irtA:
undetectable		 5kkzK-4irtA:
18.75
5kkzQ-4irtA:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_O_ASCO1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 4irt UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		4 / 7 HIS A  90
ILE A  92
VAL A  35
TYR A  57
 None
 1.12A 5kkzM-4irtA:
0.0
5kkzO-4irtA:
undetectable		 5kkzM-4irtA:
18.62
5kkzO-4irtA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 4irt UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		4 / 6 ILE A 120
ILE A  93
HIS A 104
PHE A 400
 None
 0.88A 5vkqA-4irtA:
undetectable
5vkqB-4irtA:
undetectable		 5vkqA-4irtA:
12.39
5vkqB-4irtA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 4irt UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		4 / 6 PHE A 400
ILE A 120
ILE A  93
HIS A 104
 None
 0.86A 5vkqA-4irtA:
undetectable
5vkqD-4irtA:
undetectable		 5vkqA-4irtA:
12.39
5vkqD-4irtA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_D_CVID301_1
(REGULATORY PROTEIN
TETR)		 4irt UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		4 / 8 GLU A 191
ILE A 188
TRP A 198
GLN A 199
 None
EDO  A 510 (-3.9A)
None
None
 1.08A 5vlmD-4irtA:
undetectable		 5vlmD-4irtA:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCP_A_BRLA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4irt UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		5 / 12 CYH A 117
SER A 106
HIS A 109
LEU A  63
LEU A 114
 None
 1.44A 5ycpA-4irtA:
undetectable		 5ycpA-4irtA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_A_AQ4A602_0
(CYTOCHROME P450 1A1)		 4irt UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		5 / 12 SER A 367
ASN A 280
ASN A 302
ASP A 363
GLY A 341
 CL  A 502 (-4.3A)
None
None
None
None
 1.19A 6dwnA-4irtA:
undetectable		 6dwnA-4irtA:
11.50