SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4irv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3004_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 4irv APOPTOSIS-STIMULATIN
G OF P53 PROTEIN 2
CYTOTOXICITY-ASSOCIA
TED IMMUNODOMINANT
ANTIGEN
(Helicobacter
pylori;
Homo
sapiens) 		4 / 5 LYS E 751
ILE A  99
PHE A 216
ASP A 214
 None
 1.05A 3kp6A-4irvE:
undetectable
3kp6B-4irvE:
undetectable		 3kp6A-4irvE:
17.11
3kp6B-4irvE:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R1Z_A_AERA601_1
(CYP17A1 PROTEIN)		 4irv CYTOTOXICITY-ASSOCIA
TED IMMUNODOMINANT
ANTIGEN
(Helicobacter
pylori) 		5 / 9 ALA A  62
ILE A 215
GLY A 174
ALA A 173
VAL A 107
 None
 1.27A 4r1zA-4irvA:
undetectable		 4r1zA-4irvA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_A_RBFA201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 4irv CYTOTOXICITY-ASSOCIA
TED IMMUNODOMINANT
ANTIGEN
(Helicobacter
pylori) 		4 / 8 VAL A  37
LEU A 165
ILE A 143
PHE A 117
 None
 0.74A 4r38A-4irvA:
undetectable		 4r38A-4irvA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_B_SAMB501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 4irv CYTOTOXICITY-ASSOCIA
TED IMMUNODOMINANT
ANTIGEN
(Helicobacter
pylori) 		5 / 9 ILE A 177
GLY A 174
LEU A  98
LEU A 104
ALA A  62
 None
 0.96A 5o96A-4irvA:
undetectable
5o96B-4irvA:
undetectable		 5o96A-4irvA:
19.92
5o96B-4irvA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MA6_A_MYTA603_0
(CYTOCHROME P450 3A4)		 4irv CYTOTOXICITY-ASSOCIA
TED IMMUNODOMINANT
ANTIGEN
APOPTOSIS-STIMULATIN
G OF P53 PROTEIN 2
(Helicobacter
pylori;
Homo
sapiens) 		4 / 6 SER A 110
ALA A 168
THR A 126
ALA E 760
 None
 1.06A 6ma6A-4irvA:
undetectable		 6ma6A-4irvA:
12.22