SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4is8'

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1S9P_B_DESB459_1 (ESTROGEN-RELATED RECEPTOR GAMMA)	4is8	NUCLEAR RECEPTOR SUBFAMILY 5 GROUP A MEMBER 2 (Homo sapiens)	5 / 12	CYH A 346 ALA A 349 LEU A 386 ARG A 393 LEU A 427	None	0.88A	1s9pB-4is8A: 23.3	1s9pB-4is8A: 32.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2AVD_B_SAMB601_1 (CATECHOL-O-METHYLTRA NSFERASE)	4is8	NUCLEAR RECEPTOR SUBFAMILY 5 GROUP A MEMBER 2 (Homo sapiens)	3 / 3	SER A 362 GLU A 312 ASP A 389	None	0.78A	2avdB-4is8A: undetectable	2avdB-4is8A: 21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3APW_B_DP0B190_1 (ALPHA-1-ACID GLYCOPROTEIN 2)	4is8	NUCLEAR RECEPTOR SUBFAMILY 5 GROUP A MEMBER 2 (Homo sapiens)	5 / 12	VAL A 318 ILE A 322 LEU A 531 GLN A 351 ALA A 360	None	1.14A	3apwB-4is8A: undetectable	3apwB-4is8A: 20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3U52_A_CUA515_0 (PHENOL HYDROXYLASE COMPONENT PHL PHENOL HYDROXYLASE COMPONENT PHN)	4is8	NUCLEAR RECEPTOR SUBFAMILY 5 GROUP A MEMBER 2 (Homo sapiens)	3 / 3	HIS A 537 HIS A 521 ILE A 533	None	0.85A	3u52A-4is8A: undetectable 3u52C-4is8A: undetectable	3u52A-4is8A: 15.86 3u52C-4is8A: 22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K4Y_A_ACTA502_0 (RNA-DEPENDENT RNA POLYMERASE)	4is8	NUCLEAR RECEPTOR SUBFAMILY 5 GROUP A MEMBER 2 (Homo sapiens)	4 / 5	LYS A 370 LEU A 369 GLU A 368 LEU A 469	None	1.35A	4k4yA-4is8A: 0.7	4k4yA-4is8A: 18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K4Y_E_ACTE503_0 (RNA-DEPENDENT RNA POLYMERASE)	4is8	NUCLEAR RECEPTOR SUBFAMILY 5 GROUP A MEMBER 2 (Homo sapiens)	4 / 4	LYS A 370 LEU A 369 GLU A 368 LEU A 469	None	1.37A	4k4yE-4is8A: undetectable	4k4yE-4is8A: 18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K4Y_I_ACTI503_0 (RNA-DEPENDENT RNA POLYMERASE)	4is8	NUCLEAR RECEPTOR SUBFAMILY 5 GROUP A MEMBER 2 (Homo sapiens)	4 / 5	LYS A 370 LEU A 369 GLU A 368 LEU A 469	None	1.35A	4k4yI-4is8A: undetectable	4k4yI-4is8A: 18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5I1N_G_DVAG9_0 (D-VILLIN HEADPIECE SUBDOMAIN VILLIN-1)	4is8	NUCLEAR RECEPTOR SUBFAMILY 5 GROUP A MEMBER 2 (Homo sapiens)	3 / 3	ALA A 423 ASN A 426 LEU A 427	None	0.32A	5i1nB-4is8A: undetectable	5i1nB-4is8A: 9.61