SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4isb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E06_B_IPBB600_0
(ODORANT-BINDING
PROTEIN)		 4isb LONG CHAIN FATTY
ACID COA LIGASE
FADD10
(Mycobacterium
tuberculosis) 		4 / 4 ILE A 226
MET A  95
VAL A  16
GLY A 228
 None
 1.30A 1e06B-4isbA:
undetectable		 1e06B-4isbA:
15.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQG_A_IBPA701_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 4isb LONG CHAIN FATTY
ACID COA LIGASE
FADD10
(Mycobacterium
tuberculosis) 		5 / 9 VAL A  83
LEU A 233
ILE A 175
ALA A 173
LEU A 172
 None
 1.06A 1eqgA-4isbA:
undetectable		 1eqgA-4isbA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICR_A_NIOA604_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 4isb LONG CHAIN FATTY
ACID COA LIGASE
FADD10
(Mycobacterium
tuberculosis) 		4 / 5 SER A  40
THR A  39
GLU A  78
GLY A  76
 None
 0.80A 1icrA-4isbA:
undetectable
1icrB-4isbA:
undetectable		 1icrA-4isbA:
18.55
1icrB-4isbA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICR_B_NIOB602_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 4isb LONG CHAIN FATTY
ACID COA LIGASE
FADD10
(Mycobacterium
tuberculosis) 		4 / 5 GLU A  78
GLY A  76
SER A  40
THR A  39
 None
 0.79A 1icrA-4isbA:
undetectable
1icrB-4isbA:
undetectable		 1icrA-4isbA:
18.55
1icrB-4isbA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_A_NIOA221_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 4isb LONG CHAIN FATTY
ACID COA LIGASE
FADD10
(Mycobacterium
tuberculosis) 		4 / 6 SER A  40
THR A  39
GLU A  78
GLY A  76
 None
 0.76A 1icuA-4isbA:
undetectable
1icuB-4isbA:
undetectable		 1icuA-4isbA:
18.55
1icuB-4isbA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_B_NIOB219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 4isb LONG CHAIN FATTY
ACID COA LIGASE
FADD10
(Mycobacterium
tuberculosis) 		4 / 6 GLU A  78
GLY A  76
SER A  40
THR A  39
 None
 0.78A 1icuA-4isbA:
undetectable
1icuB-4isbA:
undetectable		 1icuA-4isbA:
18.55
1icuB-4isbA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_C_NIOC225_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 4isb LONG CHAIN FATTY
ACID COA LIGASE
FADD10
(Mycobacterium
tuberculosis) 		4 / 6 SER A  40
THR A  39
GLU A  78
GLY A  76
 None
 0.78A 1icuC-4isbA:
undetectable
1icuD-4isbA:
undetectable		 1icuC-4isbA:
18.55
1icuD-4isbA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICV_C_NIOC708_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 4isb LONG CHAIN FATTY
ACID COA LIGASE
FADD10
(Mycobacterium
tuberculosis) 		4 / 5 SER A  40
THR A  39
GLU A  78
GLY A  76
 None
 0.79A 1icvC-4isbA:
undetectable
1icvD-4isbA:
undetectable		 1icvC-4isbA:
18.55
1icvD-4isbA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICV_D_NIOD706_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 4isb LONG CHAIN FATTY
ACID COA LIGASE
FADD10
(Mycobacterium
tuberculosis) 		4 / 5 GLU A  78
GLY A  76
SER A  40
THR A  39
 None
 0.80A 1icvC-4isbA:
undetectable
1icvD-4isbA:
undetectable		 1icvC-4isbA:
18.55
1icvD-4isbA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_A_BEZA524_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 4isb LONG CHAIN FATTY
ACID COA LIGASE
FADD10
(Mycobacterium
tuberculosis) 		4 / 6 SER A  40
THR A  39
GLU A  78
GLY A  76
 None
 0.78A 1kqbA-4isbA:
undetectable
1kqbB-4isbA:
undetectable		 1kqbA-4isbA:
17.03
1kqbB-4isbA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_B_BEZB525_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 4isb LONG CHAIN FATTY
ACID COA LIGASE
FADD10
(Mycobacterium
tuberculosis) 		4 / 5 GLU A  78
GLY A  76
SER A  40
THR A  39
 None
 0.78A 1kqbA-4isbA:
undetectable
1kqbB-4isbA:
undetectable		 1kqbA-4isbA:
17.03
1kqbB-4isbA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_C_BEZC522_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 4isb LONG CHAIN FATTY
ACID COA LIGASE
FADD10
(Mycobacterium
tuberculosis) 		4 / 6 SER A  40
THR A  39
GLU A  78
GLY A  76
 None
 0.78A 1kqbC-4isbA:
undetectable
1kqbD-4isbA:
undetectable		 1kqbC-4isbA:
17.03
1kqbD-4isbA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_D_BEZD523_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 4isb LONG CHAIN FATTY
ACID COA LIGASE
FADD10
(Mycobacterium
tuberculosis) 		4 / 6 GLU A  78
GLY A  76
SER A  40
THR A  39
 None
 0.77A 1kqbC-4isbA:
undetectable
1kqbD-4isbA:
undetectable		 1kqbC-4isbA:
17.03
1kqbD-4isbA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZX_B_TRPB603_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 4isb LONG CHAIN FATTY
ACID COA LIGASE
FADD10
(Mycobacterium
tuberculosis) 		5 / 12 TYR A  80
THR A  79
GLY A  76
GLY A 246
GLU A 247
 None
 1.27A 2azxB-4isbA:
undetectable		 2azxB-4isbA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EGV_A_SAMA1300_0
(UPF0088 PROTEIN
AQ_165)		 4isb LONG CHAIN FATTY
ACID COA LIGASE
FADD10
(Mycobacterium
tuberculosis) 		5 / 12 LEU A 118
VAL A  71
LEU A  54
LEU A  81
THR A  79
 None
 1.00A 2egvA-4isbA:
undetectable		 2egvA-4isbA:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EGV_B_SAMB1400_0
(UPF0088 PROTEIN
AQ_165)		 4isb LONG CHAIN FATTY
ACID COA LIGASE
FADD10
(Mycobacterium
tuberculosis) 		5 / 12 LEU A 118
VAL A  71
LEU A  54
LEU A  81
THR A  79
 None
 1.01A 2egvB-4isbA:
undetectable		 2egvB-4isbA:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_K_BO2K1402_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 4isb LONG CHAIN FATTY
ACID COA LIGASE
FADD10
(Mycobacterium
tuberculosis) 		5 / 10 THR A 488
ALA A 491
VAL A 471
GLY A 446
ALA A 444
 None
 1.04A 2f16K-4isbA:
undetectable
2f16L-4isbA:
undetectable		 2f16K-4isbA:
17.65
2f16L-4isbA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_A_SAMA2001_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 4isb LONG CHAIN FATTY
ACID COA LIGASE
FADD10
(Mycobacterium
tuberculosis) 		4 / 7 TYR A  80
GLY A  76
THR A 244
ASP A  74
 None
 1.08A 2g70A-4isbA:
undetectable		 2g70A-4isbA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_C_SAMC1003_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 4isb LONG CHAIN FATTY
ACID COA LIGASE
FADD10
(Mycobacterium
tuberculosis) 		5 / 12 ALA A  91
SER A  67
ALA A 115
ALA A  85
GLY A  90
 None
 1.20A 2igtC-4isbA:
3.2		 2igtC-4isbA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBL_A_CAMA517_0
(CYTOCHROME P450-CAM)		 4isb LONG CHAIN FATTY
ACID COA LIGASE
FADD10
(Mycobacterium
tuberculosis) 		4 / 7 LEU A 266
VAL A 291
THR A 264
VAL A 285
 None
 0.93A 2qblA-4isbA:
undetectable		 2qblA-4isbA:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VH3_A_DAHA2_1
(RANASMURFIN)		 4isb LONG CHAIN FATTY
ACID COA LIGASE
FADD10
(Mycobacterium
tuberculosis) 		5 / 9 ALA A 300
ALA A 298
SER A 296
SER A 524
ALA A 527
 None
 1.30A 2vh3A-4isbA:
undetectable		 2vh3A-4isbA:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		 4isb LONG CHAIN FATTY
ACID COA LIGASE
FADD10
(Mycobacterium
tuberculosis) 		4 / 8 ILE A 255
LEU A 266
VAL A 267
LEU A 270
 None
 0.75A 2w98B-4isbA:
3.3		 2w98B-4isbA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WQ5_A_MIYA1120_1
(PHOSPHOLIPASE A2,
ACIDIC)		 4isb LONG CHAIN FATTY
ACID COA LIGASE
FADD10
(Mycobacterium
tuberculosis) 		4 / 7 LEU A  17
ALA A  55
GLY A  52
PHE A  21
 None
 0.90A 2wq5A-4isbA:
undetectable		 2wq5A-4isbA:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_A_HSMA1161_1
(ALLERGEN ARG R 1)		 4isb LONG CHAIN FATTY
ACID COA LIGASE
FADD10
(Mycobacterium
tuberculosis) 		4 / 5 VAL A 291
TYR A 293
VAL A 303
ASP A 302
 None
 1.17A 2x45A-4isbA:
undetectable		 2x45A-4isbA:
13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1161_1
(ALLERGEN ARG R 1)		 4isb LONG CHAIN FATTY
ACID COA LIGASE
FADD10
(Mycobacterium
tuberculosis) 		4 / 5 VAL A 291
TYR A 293
VAL A 303
ASP A 302
 None
 1.23A 2x45C-4isbA:
undetectable		 2x45C-4isbA:
13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUH_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 4isb LONG CHAIN FATTY
ACID COA LIGASE
FADD10
(Mycobacterium
tuberculosis) 		4 / 6 THR A 193
LEU A 189
VAL A 187
VAL A 404
 None
 1.10A 2zuhA-4isbA:
undetectable		 2zuhA-4isbA:
24.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A2Q_A_ACAA601_1
(6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE)		 4isb LONG CHAIN FATTY
ACID COA LIGASE
FADD10
(Mycobacterium
tuberculosis) 		4 / 7 GLY A 468
ALA A 526
ALA A 529
ILE A 428
 None
 0.78A 3a2qA-4isbA:
undetectable		 3a2qA-4isbA:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_F_ACRF5044_2
(GLUCOSYLTRANSFERASE-
SI)		 4isb LONG CHAIN FATTY
ACID COA LIGASE
FADD10
(Mycobacterium
tuberculosis) 		3 / 3 LEU A  84
TRP A 230
TYR A  80
 None
 1.02A 3aicF-4isbA:
undetectable		 3aicF-4isbA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MS9_A_STIA1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 4isb LONG CHAIN FATTY
ACID COA LIGASE
FADD10
(Mycobacterium
tuberculosis) 		4 / 6 VAL A 450
VAL A 507
ILE A 512
ARG A 492
 None
 1.05A 3ms9A-4isbA:
undetectable		 3ms9A-4isbA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MS9_B_STIB1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 4isb LONG CHAIN FATTY
ACID COA LIGASE
FADD10
(Mycobacterium
tuberculosis) 		4 / 7 VAL A 450
VAL A 507
ILE A 512
ARG A 492
 None
 1.02A 3ms9B-4isbA:
undetectable		 3ms9B-4isbA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_A_STIA1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 4isb LONG CHAIN FATTY
ACID COA LIGASE
FADD10
(Mycobacterium
tuberculosis) 		4 / 6 VAL A 450
VAL A 507
ILE A 512
ARG A 492
 None
 1.01A 3mssA-4isbA:
undetectable		 3mssA-4isbA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_C_STIC1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 4isb LONG CHAIN FATTY
ACID COA LIGASE
FADD10
(Mycobacterium
tuberculosis) 		4 / 6 VAL A 450
VAL A 507
ILE A 512
ARG A 492
 None
 1.03A 3mssC-4isbA:
undetectable		 3mssC-4isbA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDI_A_SAMA601_0
(METHYLTRANSFERASE)		 4isb LONG CHAIN FATTY
ACID COA LIGASE
FADD10
(Mycobacterium
tuberculosis) 		5 / 12 GLU A 106
ILE A 105
PHE A 108
ALA A 133
ILE A  72
 None
 1.36A 3ndiA-4isbA:
2.7		 3ndiA-4isbA:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PYY_A_STIA3_2
(V-ABL ABELSON MURINE
LEUKEMIA VIRAL
ONCOGENE HOMOLOG 1
ISOFORM B VARIANT)		 4isb LONG CHAIN FATTY
ACID COA LIGASE
FADD10
(Mycobacterium
tuberculosis) 		4 / 6 VAL A 450
VAL A 507
ILE A 512
ARG A 492
 None
 0.96A 3pyyA-4isbA:
undetectable		 3pyyA-4isbA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SOA_A_DB8A445_1
(CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE II
SUBUNIT ALPHA WITH A
BETA 7 LINKER)		 4isb LONG CHAIN FATTY
ACID COA LIGASE
FADD10
(Mycobacterium
tuberculosis) 		4 / 6 LEU A  70
VAL A  94
MET A 174
PHE A 176
 None
 0.93A 3soaA-4isbA:
undetectable		 3soaA-4isbA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BBO_B_ACTB1114_0
(BLR5658 PROTEIN)		 4isb LONG CHAIN FATTY
ACID COA LIGASE
FADD10
(Mycobacterium
tuberculosis) 		3 / 3 TRP A 211
TRP A 231
THR A 263
 None
 1.09A 4bboB-4isbA:
undetectable		 4bboB-4isbA:
14.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5O_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 4isb LONG CHAIN FATTY
ACID COA LIGASE
FADD10
(Mycobacterium
tuberculosis) 		4 / 7 ILE A 361
PRO A 363
ILE A 400
ASP A 401
 None
 1.08A 4w5oA-4isbA:
1.8		 4w5oA-4isbA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4E_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 4isb LONG CHAIN FATTY
ACID COA LIGASE
FADD10
(Mycobacterium
tuberculosis) 		4 / 7 ILE A 361
PRO A 363
ILE A 400
ASP A 401
 None
 1.07A 4z4eA-4isbA:
2.5		 4z4eA-4isbA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4G_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 4isb LONG CHAIN FATTY
ACID COA LIGASE
FADD10
(Mycobacterium
tuberculosis) 		4 / 7 ILE A 361
PRO A 363
ILE A 400
ASP A 401
 None
 1.08A 4z4gA-4isbA:
3.8		 4z4gA-4isbA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KF8_A_GCSA404_1
(PREDICTED
ACETYLTRANSFERASE)		 4isb LONG CHAIN FATTY
ACID COA LIGASE
FADD10
(Mycobacterium
tuberculosis) 		4 / 8 PRO A 121
GLY A  76
PRO A  77
ASP A  74
 None
 1.15A 5kf8A-4isbA:
undetectable		 5kf8A-4isbA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KGP_A_GCSA407_1
(PREDICTED
ACETYLTRANSFERASE)		 4isb LONG CHAIN FATTY
ACID COA LIGASE
FADD10
(Mycobacterium
tuberculosis) 		4 / 8 PRO A 121
GLY A  76
PRO A  77
ASP A  74
 None
 1.13A 5kgpA-4isbA:
undetectable		 5kgpA-4isbA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MLM_A_STRA401_1
(-)		 4isb LONG CHAIN FATTY
ACID COA LIGASE
FADD10
(Mycobacterium
tuberculosis) 		5 / 12 PHE A 108
ILE A 105
ALA A 120
SER A  82
ILE A  72
 None
 1.46A 5mlmA-4isbA:
4.5		 5mlmA-4isbA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWV_A_ACAA18_1
(SCRFP-TAG,GP41)		 4isb LONG CHAIN FATTY
ACID COA LIGASE
FADD10
(Mycobacterium
tuberculosis) 		5 / 12 GLY A 422
LYS A 421
GLU A 411
LEU A 355
LEU A 410
 None
 1.16A 5nwvA-4isbA:
undetectable		 5nwvA-4isbA:
4.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIP_C_HFGC1003_0
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 4isb LONG CHAIN FATTY
ACID COA LIGASE
FADD10
(Mycobacterium
tuberculosis) 		5 / 12 LEU A 290
VAL A 209
THR A 331
GLU A 307
GLY A 334
 None
 1.12A 5xipC-4isbA:
undetectable		 5xipC-4isbA:
21.34