SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4iu4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_B_BEZB504_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 4iu4 ARGINASE
(Leishmania
mexicana) 		4 / 7 LEU A 108
ILE A  17
ALA A 311
ILE A 304
 None
 0.98A 1oniB-4iu4A:
undetectable
1oniC-4iu4A:
undetectable		 1oniB-4iu4A:
18.48
1oniC-4iu4A:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 4iu4 ARGINASE
(Leishmania
mexicana) 		5 / 12 HIS A 139
ASP A 245
THR A 255
GLY A 155
HIS A 154
 MN  A 402 ( 3.4A)
MN  A 402 ( 2.0A)
None
S2C  A 405 ( 3.7A)
S2C  A 405 (-3.2A)
 1.34A 1v8bA-4iu4A:
2.4		 1v8bA-4iu4A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_B_ADNB1502_1
(ADENOSYLHOMOCYSTEINA
SE)		 4iu4 ARGINASE
(Leishmania
mexicana) 		5 / 12 HIS A 139
ASP A 245
THR A 255
GLY A 155
HIS A 154
 MN  A 402 ( 3.4A)
MN  A 402 ( 2.0A)
None
S2C  A 405 ( 3.7A)
S2C  A 405 (-3.2A)
 1.34A 1v8bB-4iu4A:
2.4		 1v8bB-4iu4A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_D_ADND3502_1
(ADENOSYLHOMOCYSTEINA
SE)		 4iu4 ARGINASE
(Leishmania
mexicana) 		5 / 12 HIS A 139
ASP A 245
THR A 255
GLY A 155
HIS A 154
 MN  A 402 ( 3.4A)
MN  A 402 ( 2.0A)
None
S2C  A 405 ( 3.7A)
S2C  A 405 (-3.2A)
 1.33A 1v8bD-4iu4A:
2.6		 1v8bD-4iu4A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO7_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4iu4 ARGINASE
(Leishmania
mexicana) 		3 / 3 LEU A 158
PRO A 157
LEU A 161
 None
 0.58A 2po7B-4iu4A:
3.2		 2po7B-4iu4A:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_D_SALD1300_1
(LYSR-TYPE REGULATORY
PROTEIN)		 4iu4 ARGINASE
(Leishmania
mexicana) 		5 / 12 ILE A  77
GLY A  78
GLY A 151
LEU A 153
PRO A 170
 None
 0.87A 2y7kD-4iu4A:
undetectable		 2y7kD-4iu4A:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUL_A_SAMA376_1
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 4iu4 ARGINASE
(Leishmania
mexicana) 		3 / 3 SER A 150
GLU A 288
ASP A 285
 S2C  A 405 (-2.5A)
S2C  A 405 (-3.6A)
None
 0.83A 2zulA-4iu4A:
undetectable		 2zulA-4iu4A:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A35_A_RBFA191_1
(LUMAZINE PROTEIN)		 4iu4 ARGINASE
(Leishmania
mexicana) 		5 / 12 SER A 159
LEU A 158
ASP A 137
ALA A 140
ILE A 200
 None
None
MN  A 401 (-2.6A)
None
None
 1.20A 3a35A-4iu4A:
undetectable		 3a35A-4iu4A:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A35_B_RBFB191_1
(LUMAZINE PROTEIN)		 4iu4 ARGINASE
(Leishmania
mexicana) 		5 / 12 SER A 159
LEU A 158
ASP A 137
ALA A 140
ILE A 200
 None
None
MN  A 401 (-2.6A)
None
None
 1.16A 3a35B-4iu4A:
undetectable		 3a35B-4iu4A:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A3B_A_RBFA191_1
(LUMAZINE PROTEIN)		 4iu4 ARGINASE
(Leishmania
mexicana) 		5 / 12 SER A 159
LEU A 158
ASP A 137
ALA A 140
ILE A 200
 None
None
MN  A 401 (-2.6A)
None
None
 1.21A 3a3bA-4iu4A:
undetectable		 3a3bA-4iu4A:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_A_DGXA1_2
(NUCLEAR RECEPTOR
ROR-GAMMA)		 4iu4 ARGINASE
(Leishmania
mexicana) 		3 / 3 TRP A 135
VAL A  97
ARG A 105
 None
 0.75A 3b0wA-4iu4A:
undetectable		 3b0wA-4iu4A:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_D_ADND500_1
(ADENOSYLHOMOCYSTEINA
SE)		 4iu4 ARGINASE
(Leishmania
mexicana) 		5 / 12 HIS A 139
ASP A 245
THR A 255
GLY A 155
HIS A 154
 MN  A 402 ( 3.4A)
MN  A 402 ( 2.0A)
None
S2C  A 405 ( 3.7A)
S2C  A 405 (-3.2A)
 1.32A 3ce6D-4iu4A:
2.3		 3ce6D-4iu4A:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMH_A_SAMA384_1
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 4iu4 ARGINASE
(Leishmania
mexicana) 		3 / 3 SER A 150
GLU A 288
ASP A 285
 S2C  A 405 (-2.5A)
S2C  A 405 (-3.6A)
None
 0.79A 3dmhA-4iu4A:
2.5		 3dmhA-4iu4A:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL5_B_1UNB201_2
(PROTEASE)		 4iu4 ARGINASE
(Leishmania
mexicana) 		5 / 12 ASP A 285
VAL A 244
GLY A 112
THR A 255
THR A 257
 None
None
None
None
S2C  A 405 (-3.4A)
 0.89A 3el5B-4iu4A:
undetectable		 3el5B-4iu4A:
16.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GN0_A_DMOA551_1
(ARGINASE-1)		 4iu4 ARGINASE
(Leishmania
mexicana) 		9 / 9 HIS A 139
ASP A 141
ASN A 143
SER A 150
HIS A 154
GLY A 155
ASP A 194
GLU A 197
THR A 257
 MN  A 402 ( 3.4A)
MN  A 401 ( 2.5A)
S2C  A 405 (-3.8A)
S2C  A 405 (-2.5A)
S2C  A 405 (-3.2A)
S2C  A 405 ( 3.7A)
S2C  A 405 (-2.4A)
S2C  A 405 ( 4.2A)
S2C  A 405 (-3.4A)
 0.28A 3gn0A-4iu4A:
48.7		 3gn0A-4iu4A:
42.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GN0_B_DMOB552_1
(ARGINASE-1)		 4iu4 ARGINASE
(Leishmania
mexicana) 		9 / 9 HIS A 139
ASP A 141
ASN A 143
SER A 150
HIS A 154
GLY A 155
ASP A 194
GLU A 197
THR A 257
 MN  A 402 ( 3.4A)
MN  A 401 ( 2.5A)
S2C  A 405 (-3.8A)
S2C  A 405 (-2.5A)
S2C  A 405 (-3.2A)
S2C  A 405 ( 3.7A)
S2C  A 405 (-2.4A)
S2C  A 405 ( 4.2A)
S2C  A 405 (-3.4A)
 0.23A 3gn0B-4iu4A:
48.7		 3gn0B-4iu4A:
42.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OND_A_ADNA506_1
(ADENOSYLHOMOCYSTEINA
SE)		 4iu4 ARGINASE
(Leishmania
mexicana) 		5 / 12 HIS A 139
ASP A 245
THR A 255
GLY A 155
HIS A 154
 MN  A 402 ( 3.4A)
MN  A 402 ( 2.0A)
None
S2C  A 405 ( 3.7A)
S2C  A 405 (-3.2A)
 1.35A 3ondA-4iu4A:
2.2		 3ondA-4iu4A:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OND_B_ADNB507_1
(ADENOSYLHOMOCYSTEINA
SE)		 4iu4 ARGINASE
(Leishmania
mexicana) 		5 / 12 HIS A 139
ASP A 245
THR A 255
GLY A 155
HIS A 154
 MN  A 402 ( 3.4A)
MN  A 402 ( 2.0A)
None
S2C  A 405 ( 3.7A)
S2C  A 405 (-3.2A)
 1.35A 3ondB-4iu4A:
undetectable		 3ondB-4iu4A:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UUD_B_ESTB600_1
(ESTROGEN RECEPTOR)		 4iu4 ARGINASE
(Leishmania
mexicana) 		5 / 10 MET A 315
LEU A  38
LEU A  39
MET A  15
LEU A 284
 None
 1.39A 3uudB-4iu4A:
undetectable		 3uudB-4iu4A:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BLV_A_SAMA1281_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 4iu4 ARGINASE
(Leishmania
mexicana) 		5 / 12 GLY A  34
GLY A  30
LEU A  43
ASP A  36
GLY A 307
 None
 1.17A 4blvA-4iu4A:
5.1		 4blvA-4iu4A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_J_KANJ301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4iu4 ARGINASE
(Leishmania
mexicana) 		4 / 6 ASP A 194
ASP A 243
ASP A 141
GLU A 197
 S2C  A 405 (-2.4A)
MN  A 402 (-2.8A)
MN  A 401 ( 2.5A)
S2C  A 405 ( 4.2A)
 1.31A 4gkhJ-4iu4A:
undetectable		 4gkhJ-4iu4A:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L3G_F_ACTF401_0
(METHYLAMINE
DEHYDROGENASE HEAVY
CHAIN)		 4iu4 ARGINASE
(Leishmania
mexicana) 		3 / 3 ARG A  58
LEU A  19
GLU A  57
 None
 0.76A 4l3gF-4iu4A:
undetectable		 4l3gF-4iu4A:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJT_B_017B101_1
(PROTEASE)		 4iu4 ARGINASE
(Leishmania
mexicana) 		5 / 11 LEU A 263
ASP A 302
VAL A 252
THR A 246
ILE A 247
 None
 0.95A 4njtA-4iu4A:
undetectable		 4njtA-4iu4A:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O4D_A_ACTA406_0
(INOSITOL
HEXAKISPHOSPHATE
KINASE)		 4iu4 ARGINASE
(Leishmania
mexicana) 		4 / 7 ASP A 137
THR A 246
ARG A 191
HIS A 139
 MN  A 401 (-2.6A)
None
None
MN  A 402 ( 3.4A)
 1.31A 4o4dA-4iu4A:
undetectable		 4o4dA-4iu4A:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q5M_A_ROCA1101_3
(PROTEASE)		 4iu4 ARGINASE
(Leishmania
mexicana) 		3 / 3 ASP A 137
ASP A 141
ASN A 152
 MN  A 401 (-2.6A)
MN  A 401 ( 2.5A)
None
 0.75A 4q5mA-4iu4A:
undetectable		 4q5mA-4iu4A:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QC6_B_KANB201_2
(BIFUNCTIONAL AAC/APH)		 4iu4 ARGINASE
(Leishmania
mexicana) 		3 / 3 LEU A  33
ASP A  36
TYR A  37
 None
 0.39A 4qc6B-4iu4A:
undetectable		 4qc6B-4iu4A:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RKU_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 4iu4 ARGINASE
(Leishmania
mexicana) 		4 / 8 MET A  15
PHE A 106
ALA A 276
LEU A 281
 None
 0.92A 4rkuA-4iu4A:
undetectable
4rkuJ-4iu4A:
undetectable		 4rkuA-4iu4A:
18.50
4rkuJ-4iu4A:
8.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_B_478B101_1
(HIV-1 PROTEASE)		 4iu4 ARGINASE
(Leishmania
mexicana) 		5 / 11 LEU A 263
ASP A 302
VAL A 252
THR A 246
ILE A 247
 None
 0.95A 4rvjA-4iu4A:
undetectable		 4rvjA-4iu4A:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_D_478D101_1
(HIV-1 PROTEASE)		 4iu4 ARGINASE
(Leishmania
mexicana) 		5 / 11 LEU A 263
ASP A 302
VAL A 252
THR A 246
ILE A 247
 None
 0.96A 4rvjC-4iu4A:
undetectable		 4rvjC-4iu4A:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNU_C_QDNC602_1
(CYTOCHROME P450 2D6)		 4iu4 ARGINASE
(Leishmania
mexicana) 		5 / 11 LEU A 271
GLY A 189
LEU A 190
PHE A 209
ALA A 226
 None
 1.35A 4wnuC-4iu4A:
undetectable		 4wnuC-4iu4A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XK8_A_PQNA844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 4iu4 ARGINASE
(Leishmania
mexicana) 		4 / 7 MET A  15
PHE A 106
ALA A 276
LEU A 281
 None
 0.96A 4xk8A-4iu4A:
undetectable		 4xk8A-4iu4A:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		 4iu4 ARGINASE
(Leishmania
mexicana) 		4 / 8 GLU A 267
GLY A 262
GLY A 261
VAL A 214
 None
 0.79A 5f8yA-4iu4A:
undetectable		 5f8yA-4iu4A:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		 4iu4 ARGINASE
(Leishmania
mexicana) 		4 / 8 GLU A 267
GLY A 262
GLY A 261
VAL A 214
 None
 0.78A 5f8yB-4iu4A:
undetectable		 5f8yB-4iu4A:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H2U_A_1N1A501_2
(PROTEIN-TYROSINE
KINASE 6)		 4iu4 ARGINASE
(Leishmania
mexicana) 		3 / 3 ILE A  93
MET A  15
ASP A 285
 None
 0.75A 5h2uA-4iu4A:
undetectable		 5h2uA-4iu4A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HYR_B_ESTB601_1
(ESTROGEN RECEPTOR)		 4iu4 ARGINASE
(Leishmania
mexicana) 		5 / 11 MET A 315
LEU A  38
LEU A  39
MET A  15
LEU A 284
 None
 1.37A 5hyrB-4iu4A:
undetectable		 5hyrB-4iu4A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_B_ADNB502_1
(ADENOSYLHOMOCYSTEINA
SE)		 4iu4 ARGINASE
(Leishmania
mexicana) 		5 / 12 HIS A 139
ASP A 245
THR A 255
GLY A 155
HIS A 154
 MN  A 402 ( 3.4A)
MN  A 402 ( 2.0A)
None
S2C  A 405 ( 3.7A)
S2C  A 405 (-3.2A)
 1.30A 5m5kB-4iu4A:
2.1		 5m5kB-4iu4A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 4iu4 ARGINASE
(Leishmania
mexicana) 		5 / 12 HIS A 139
ASP A 245
THR A 255
GLY A 155
HIS A 154
 MN  A 402 ( 3.4A)
MN  A 402 ( 2.0A)
None
S2C  A 405 ( 3.7A)
S2C  A 405 (-3.2A)
 1.35A 5m66A-4iu4A:
2.3		 5m66A-4iu4A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_C_ADNC502_1
(ADENOSYLHOMOCYSTEINA
SE)		 4iu4 ARGINASE
(Leishmania
mexicana) 		5 / 12 HIS A 139
ASP A 245
THR A 255
GLY A 155
HIS A 154
 MN  A 402 ( 3.4A)
MN  A 402 ( 2.0A)
None
S2C  A 405 ( 3.7A)
S2C  A 405 (-3.2A)
 1.33A 5m66C-4iu4A:
2.3		 5m66C-4iu4A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8S_B_SAMB402_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 4iu4 ARGINASE
(Leishmania
mexicana) 		4 / 8 ALA A 140
GLU A 197
ASP A 165
ILE A 160
 None
S2C  A 405 ( 4.2A)
None
None
 0.95A 5t8sA-4iu4A:
undetectable		 5t8sA-4iu4A:
24.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UTU_F_ADNF503_1
(ADENOSYLHOMOCYSTEINA
SE)		 4iu4 ARGINASE
(Leishmania
mexicana) 		5 / 12 HIS A 139
ASP A 245
THR A 255
GLY A 155
HIS A 154
 MN  A 402 ( 3.4A)
MN  A 402 ( 2.0A)
None
S2C  A 405 ( 3.7A)
S2C  A 405 (-3.2A)
 1.32A 5utuF-4iu4A:
undetectable		 5utuF-4iu4A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WGQ_B_ESTB601_1
(ESTROGEN RECEPTOR)		 4iu4 ARGINASE
(Leishmania
mexicana) 		5 / 10 MET A 315
LEU A  38
LEU A  39
MET A  15
LEU A 284
 None
 1.33A 5wgqB-4iu4A:
undetectable		 5wgqB-4iu4A:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA504_1
(CYTOCHROME P450 2C9)		 4iu4 ARGINASE
(Leishmania
mexicana) 		4 / 8 PHE A 265
ILE A 247
PRO A 291
PRO A 253
 None
 1.08A 5x23A-4iu4A:
undetectable		 5x23A-4iu4A:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3N_B_ADNB505_1
(-)		 4iu4 ARGINASE
(Leishmania
mexicana) 		5 / 12 HIS A 139
ASP A 245
THR A 255
GLY A 155
HIS A 154
 MN  A 402 ( 3.4A)
MN  A 402 ( 2.0A)
None
S2C  A 405 ( 3.7A)
S2C  A 405 (-3.2A)
 1.31A 6f3nB-4iu4A:
undetectable		 6f3nB-4iu4A:
22.93