SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ium'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5INZ_D_DVAD15_0
(THETA DEFENSIN-2,
D-PEPTIDE
THETA DEFENSIN-2,
L-PEPTIDE)		 4ium PAPAIN-LIKE PROTEASE
2
(Equine
arteritis
virus) 		3 / 3 GLY A 352
CYH A 354
CYH A 349
 None
ZN  A 501 (-2.3A)
ZN  A 501 (-2.3A)
 0.96A 5inzB-4iumA:
undetectable		 5inzB-4iumA:
15.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCV_A_1N1A404_2
(MEMBRANE-ASSOCIATED
TYROSINE- AND
THREONINE-SPECIFIC
CDC2-INHIBITORY
KINASE)		 4ium PAPAIN-LIKE PROTEASE
2
(Equine
arteritis
virus) 		4 / 5 VAL A 384
LEU A 275
CYH A 274
ASP A 267
 None
 1.47A 5vcvA-4iumA:
undetectable		 5vcvA-4iumA:
20.31