SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4iuy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZM_A_BZMA600_0
(ODORANT-BINDING
PROTEIN)		 4iuy SHORT CHAIN
DEHYDROGENASE/REDUCT
ASE
(Acinetobacter
baumannii) 		4 / 8 ILE A 242
VAL A  89
ASN A 183
GLY A 241
 None
 0.99A 1dzmA-4iuyA:
undetectable		 1dzmA-4iuyA:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE3_B_SAMB301_0
(HYPOTHETICAL PROTEIN
PH0226)		 4iuy SHORT CHAIN
DEHYDROGENASE/REDUCT
ASE
(Acinetobacter
baumannii) 		5 / 12 ALA A 188
GLY A 190
ILE A 144
ALA A 186
SER A 149
 None
 0.88A 1ve3B-4iuyA:
6.7		 1ve3B-4iuyA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_E_ACHE1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 4iuy SHORT CHAIN
DEHYDROGENASE/REDUCT
ASE
(Acinetobacter
baumannii) 		4 / 7 GLN A 207
ILE A 193
SER A 203
TYR A 200
 None
 1.29A 2xz5D-4iuyA:
undetectable
2xz5E-4iuyA:
undetectable		 2xz5D-4iuyA:
20.73
2xz5E-4iuyA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_B_SAMB801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 4iuy SHORT CHAIN
DEHYDROGENASE/REDUCT
ASE
(Acinetobacter
baumannii) 		4 / 8 ILE A 144
ASN A 117
SER A 162
SER A 146
 None
 0.99A 2zw9B-4iuyA:
6.6		 2zw9B-4iuyA:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZN_A_SAMA401_0
(UNCHARACTERIZED
PROTEIN MJ0883)		 4iuy SHORT CHAIN
DEHYDROGENASE/REDUCT
ASE
(Acinetobacter
baumannii) 		5 / 12 TYR A  56
PHE A  28
GLY A  32
ASN A  34
VAL A  89
 None
 1.30A 2zznA-4iuyA:
6.7		 2zznA-4iuyA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_E_VDYE6178_1
(VITAMIN D
HYDROXYLASE)		 4iuy SHORT CHAIN
DEHYDROGENASE/REDUCT
ASE
(Acinetobacter
baumannii) 		5 / 12 THR A  14
ILE A 142
ALA A 186
VAL A 246
LEU A 224
 None
 1.21A 3a51E-4iuyA:
undetectable		 3a51E-4iuyA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8I_A_RO7A1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR ALPHA)		 4iuy SHORT CHAIN
DEHYDROGENASE/REDUCT
ASE
(Acinetobacter
baumannii) 		5 / 12 VAL A  73
CYH A 124
MET A 132
ILE A  87
ILE A 142
 None
 1.45A 3g8iA-4iuyA:
undetectable		 3g8iA-4iuyA:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_C_MTXC164_2
(DIHYDROFOLATE
REDUCTASE)		 4iuy SHORT CHAIN
DEHYDROGENASE/REDUCT
ASE
(Acinetobacter
baumannii) 		4 / 4 ILE A  35
ARG A 137
ILE A  11
THR A  62
 None
 1.24A 3ia4C-4iuyA:
undetectable		 3ia4C-4iuyA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JZ0_B_CLYB900_1
(LINCOSAMIDE
NUCLEOTIDYLTRANSFERA
SE)		 4iuy SHORT CHAIN
DEHYDROGENASE/REDUCT
ASE
(Acinetobacter
baumannii) 		4 / 8 TYR A  61
TYR A  10
GLU A  83
ILE A  52
 None
 0.92A 3jz0B-4iuyA:
undetectable		 3jz0B-4iuyA:
27.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7T_A_5FWA1001_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 4iuy SHORT CHAIN
DEHYDROGENASE/REDUCT
ASE
(Acinetobacter
baumannii) 		3 / 3 ASP A 111
LYS A 112
ASP A 115
 None
 0.55A 4a7tA-4iuyA:
undetectable		 4a7tA-4iuyA:
24.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IJI_H_BEZH501_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN YIBF)		 4iuy SHORT CHAIN
DEHYDROGENASE/REDUCT
ASE
(Acinetobacter
baumannii) 		4 / 7 ASN A  92
ALA A 125
VAL A  73
ARG A  70
 None
 1.14A 4ijiH-4iuyA:
undetectable		 4ijiH-4iuyA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YJI_A_TYLA502_1
(ARYL ACYLAMIDASE)		 4iuy SHORT CHAIN
DEHYDROGENASE/REDUCT
ASE
(Acinetobacter
baumannii) 		4 / 7 LEU A  45
GLY A  21
ALA A  25
ILE A  91
 None
 0.70A 4yjiA-4iuyA:
undetectable		 4yjiA-4iuyA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JNH_A_ASCA202_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 4iuy SHORT CHAIN
DEHYDROGENASE/REDUCT
ASE
(Acinetobacter
baumannii) 		3 / 3 ASN A  92
PRO A 121
GLN A 123
 None
 0.89A 6jnhA-4iuyA:
2.9		 6jnhA-4iuyA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JOG_A_ASCA202_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 4iuy SHORT CHAIN
DEHYDROGENASE/REDUCT
ASE
(Acinetobacter
baumannii) 		3 / 3 ASN A  92
PRO A 121
GLN A 123
 None
 0.91A 6jogA-4iuyA:
3.7		 6jogA-4iuyA:
21.15