SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ivf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC5_A_NCAA2001_0
(NAD-DEPENDENT
DEACETYLASE)		 4ivf PUTATIVE
UNCHARACTERIZED
PROTEIN
(Lodderomyces
elongisporus) 		4 / 7 ILE A   8
ASP A  31
ASN A  65
ASP A  63
 None
 0.98A 1yc5A-4ivfA:
undetectable		 1yc5A-4ivfA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN5_A_FUNA1356_2
(THYROXINE-BINDING
GLOBULIN)		 4ivf PUTATIVE
UNCHARACTERIZED
PROTEIN
(Lodderomyces
elongisporus) 		3 / 3 LEU A 191
ARG A 187
ILE A 193
 None
 0.62A 2xn5B-4ivfA:
undetectable		 2xn5B-4ivfA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU9_B_SPMB700_1
(POLYAMINE OXIDASE)		 4ivf PUTATIVE
UNCHARACTERIZED
PROTEIN
(Lodderomyces
elongisporus) 		4 / 7 TYR A  19
TYR A 186
TYR A 205
TYR A 151
 None
 1.32A 3ku9B-4ivfA:
undetectable		 3ku9B-4ivfA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DUB_A_LDPA501_1
(CYTOCHROME P450 BM3
VARIANT 9D7)		 4ivf PUTATIVE
UNCHARACTERIZED
PROTEIN
(Lodderomyces
elongisporus) 		4 / 6 PHE A 154
GLY A 119
PRO A 120
VAL A 115
 None
GSH  A 301 (-3.7A)
GSH  A 301 (-3.2A)
None
 0.96A 4dubA-4ivfA:
undetectable		 4dubA-4ivfA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C71_B_NCTB501_1
(AMINE OXIDASE)		 4ivf PUTATIVE
UNCHARACTERIZED
PROTEIN
(Lodderomyces
elongisporus) 		4 / 8 LEU A  10
TYR A  32
GLU A  26
THR A  12
 None
 0.90A 6c71B-4ivfA:
undetectable		 6c71B-4ivfA:
18.75