SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ix2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1HBP_A_RTLA184_0 (RETINOL BINDING PROTEIN)	4ix2	INOSINE-5'-MONOPHOSP HATE DEHYDROGENASE (Vibrio cholerae)	5 / 11	PHE A 461 ALA A 354 ALA A 352 VAL A 362 GLN A 436	None None None IMP A 501 (-4.4A) None	1.18A	1hbpA-4ix2A: undetectable	1hbpA-4ix2A: 17.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1JR1_A_MOAA1332_1 (INOSINE-5'-MONOPHOSP HATE DEHYDROGENASE 2)	4ix2	INOSINE-5'-MONOPHOSP HATE DEHYDROGENASE (Vibrio cholerae)	6 / 11	ASP A 250 SER A 251 ASN A 279 GLY A 302 CYH A 307 THR A 309	None None IMP A 501 ( 4.4A) None IMP A 501 (-4.9A) None	0.95A	1jr1A-4ix2A: 49.0	1jr1A-4ix2A: 32.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1JR1_A_MOAA1332_1 (INOSINE-5'-MONOPHOSP HATE DEHYDROGENASE 2)	4ix2	INOSINE-5'-MONOPHOSP HATE DEHYDROGENASE (Vibrio cholerae)	6 / 11	ASP A 250 SER A 252 ASN A 279 GLY A 302 CYH A 307 THR A 309	None None IMP A 501 ( 4.4A) None IMP A 501 (-4.9A) None	0.79A	1jr1A-4ix2A: 49.0	1jr1A-4ix2A: 32.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1JR1_B_MOAB1333_1 (INOSINE-5'-MONOPHOSP HATE DEHYDROGENASE 2)	4ix2	INOSINE-5'-MONOPHOSP HATE DEHYDROGENASE (Vibrio cholerae)	4 / 8	ASP A 250 ASN A 279 GLY A 302 THR A 309	None IMP A 501 ( 4.4A) None None	0.60A	1jr1B-4ix2A: 48.7	1jr1B-4ix2A: 32.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1JR1_B_MOAB1333_1 (INOSINE-5'-MONOPHOSP HATE DEHYDROGENASE 2)	4ix2	INOSINE-5'-MONOPHOSP HATE DEHYDROGENASE (Vibrio cholerae)	4 / 8	ASP A 250 SER A 252 ASN A 279 GLY A 302	None None IMP A 501 ( 4.4A) None	0.87A	1jr1B-4ix2A: 48.7	1jr1B-4ix2A: 32.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1ME7_A_MOAA600_1 (INOSINE-5'-MONOPHOSP HATE DEHYDROGENASE)	4ix2	INOSINE-5'-MONOPHOSP HATE DEHYDROGENASE (Vibrio cholerae)	6 / 8	ASP A 250 SER A 251 SER A 252 ILE A 301 GLY A 302 CYH A 307	None None None None None IMP A 501 (-4.9A)	0.85A	1me7A-4ix2A: 45.7	1me7A-4ix2A: 31.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1ME7_A_MOAA600_1 (INOSINE-5'-MONOPHOSP HATE DEHYDROGENASE)	4ix2	INOSINE-5'-MONOPHOSP HATE DEHYDROGENASE (Vibrio cholerae)	6 / 8	SER A 251 SER A 252 ASN A 279 ILE A 301 GLY A 302 CYH A 307	None None IMP A 501 ( 4.4A) None None IMP A 501 (-4.9A)	0.61A	1me7A-4ix2A: 45.7	1me7A-4ix2A: 31.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1MEH_A_MOAA600_1 (INOSINE-5'-MONOPHOSP HATE DEHYDROGENASE)	4ix2	INOSINE-5'-MONOPHOSP HATE DEHYDROGENASE (Vibrio cholerae)	6 / 10	ASP A 250 SER A 251 SER A 252 ASN A 279 ILE A 301 GLY A 302	None None None IMP A 501 ( 4.4A) None None	0.80A	1mehA-4ix2A: 44.4	1mehA-4ix2A: 31.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1MEI_A_MOAA600_1 (INOSINE-5'-MONOPHOSP HATE DEHYDROGENASE)	4ix2	INOSINE-5'-MONOPHOSP HATE DEHYDROGENASE (Vibrio cholerae)	5 / 8	ASP A 250 SER A 251 SER A 252 ASN A 279 ILE A 301	None None None IMP A 501 ( 4.4A) None	0.83A	1meiA-4ix2A: 45.5	1meiA-4ix2A: 31.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RBP_A_RTLA183_0 (PLASMA RETINOL-BINDING PROTEIN PRECURSOR)	4ix2	INOSINE-5'-MONOPHOSP HATE DEHYDROGENASE (Vibrio cholerae)	5 / 12	ALA A 355 PHE A 461 ALA A 352 VAL A 362 GLN A 436	None None None IMP A 501 (-4.4A) None	1.36A	1rbpA-4ix2A: undetectable	1rbpA-4ix2A: 17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RXC_B_URFB2011_1 (URIDINE PHOSPHORYLASE)	4ix2	INOSINE-5'-MONOPHOSP HATE DEHYDROGENASE (Vibrio cholerae)	4 / 8	THR A 266 GLY A 293 ILE A 275 VAL A 294	None	0.95A	1rxcB-4ix2A: undetectable	1rxcB-4ix2A: 24.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RXC_E_URFE2031_1 (URIDINE PHOSPHORYLASE)	4ix2	INOSINE-5'-MONOPHOSP HATE DEHYDROGENASE (Vibrio cholerae)	4 / 8	THR A 266 GLY A 293 ILE A 275 VAL A 294	None	0.99A	1rxcE-4ix2A: undetectable	1rxcE-4ix2A: 24.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RXC_I_URFI2041_1 (URIDINE PHOSPHORYLASE)	4ix2	INOSINE-5'-MONOPHOSP HATE DEHYDROGENASE (Vibrio cholerae)	4 / 8	THR A 266 GLY A 293 ILE A 275 VAL A 294	None	0.93A	1rxcI-4ix2A: undetectable	1rxcI-4ix2A: 24.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RXC_K_URFK2061_1 (URIDINE PHOSPHORYLASE)	4ix2	INOSINE-5'-MONOPHOSP HATE DEHYDROGENASE (Vibrio cholerae)	4 / 8	THR A 266 GLY A 293 ILE A 275 VAL A 294	None	0.97A	1rxcK-4ix2A: undetectable	1rxcK-4ix2A: 24.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1SG9_C_SAMC303_0 (HEMK PROTEIN)	4ix2	INOSINE-5'-MONOPHOSP HATE DEHYDROGENASE (Vibrio cholerae)	5 / 12	ILE A 276 GLY A 254 ALA A 288 SER A 252 ALA A 228	None	1.12A	1sg9C-4ix2A: undetectable	1sg9C-4ix2A: 23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ZQ9_A_SAMA4000_0 (PROBABLE DIMETHYLADENOSINE TRANSFERASE)	4ix2	INOSINE-5'-MONOPHOSP HATE DEHYDROGENASE (Vibrio cholerae)	5 / 12	ILE A 44 GLY A 68 LEU A 63 VAL A 246 ILE A 276	None	1.18A	1zq9A-4ix2A: undetectable	1zq9A-4ix2A: 21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2F8L_A_SAMA400_0 (HYPOTHETICAL PROTEIN LMO1582)	4ix2	INOSINE-5'-MONOPHOSP HATE DEHYDROGENASE (Vibrio cholerae)	5 / 12	ASN A 43 LEU A 32 VAL A 337 LEU A 36 GLY A 356	None	1.12A	2f8lA-4ix2A: undetectable	2f8lA-4ix2A: 23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2RDD_A_AICA1110_1 (ACRIFLAVINE RESISTANCE PROTEIN B)	4ix2	INOSINE-5'-MONOPHOSP HATE DEHYDROGENASE (Vibrio cholerae)	4 / 4	LYS A 385 ALA A 367 PHE A 366 GLY A 363	None None None IMP A 501 (-3.5A)	1.38A	2rddA-4ix2A: undetectable	2rddA-4ix2A: 17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VE3_B_REAB1445_1 (PUTATIVE CYTOCHROME P450 120)	4ix2	INOSINE-5'-MONOPHOSP HATE DEHYDROGENASE (Vibrio cholerae)	5 / 12	ALA A 286 THR A 321 VAL A 317 GLY A 316 PRO A 303	None	1.20A	2ve3B-4ix2A: undetectable	2ve3B-4ix2A: 20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ZMD_A_SALA201_1 (PUTATIVE TRANSCRIPTIONAL REGULATOR)	4ix2	INOSINE-5'-MONOPHOSP HATE DEHYDROGENASE (Vibrio cholerae)	4 / 8	ARG A 33 LEU A 32 ARG A 441 MET A 444	None	1.44A	3zmdA-4ix2A: undetectable 3zmdB-4ix2A: undetectable	3zmdA-4ix2A: 19.28 3zmdB-4ix2A: 19.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4AF0_A_MOAA1526_1 (INOSINE-5'-MONOPHOSP HATE DEHYDROGENASE)	4ix2	INOSINE-5'-MONOPHOSP HATE DEHYDROGENASE (Vibrio cholerae)	4 / 8	ASP A 250 SER A 251 SER A 252 ASN A 279	None None None IMP A 501 ( 4.4A)	0.74A	4af0A-4ix2A: 45.8	4af0A-4ix2A: 31.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4AF0_B_MOAB1526_1 (INOSINE-5'-MONOPHOSP HATE DEHYDROGENASE)	4ix2	INOSINE-5'-MONOPHOSP HATE DEHYDROGENASE (Vibrio cholerae)	5 / 10	ASP A 250 SER A 251 SER A 252 ASN A 279 MET A 390	None None None IMP A 501 ( 4.4A) None	0.80A	4af0B-4ix2A: 45.7	4af0B-4ix2A: 31.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DTZ_A_LDPA501_1 (CYTOCHROME P450 BM3 VARIANT 8C8)	4ix2	INOSINE-5'-MONOPHOSP HATE DEHYDROGENASE (Vibrio cholerae)	4 / 6	ALA A 296 PRO A 336 LEU A 36 THR A 37	None	0.94A	4dtzA-4ix2A: undetectable	4dtzA-4ix2A: 21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DU2_B_LDPB501_1 (CYTOCHROME P450 BM3 VARIANT B7)	4ix2	INOSINE-5'-MONOPHOSP HATE DEHYDROGENASE (Vibrio cholerae)	4 / 7	ALA A 296 PRO A 336 LEU A 36 THR A 37	None	0.89A	4du2B-4ix2A: undetectable	4du2B-4ix2A: 21.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4FO4_A_MOAA502_1 (INOSINE 5'-MONOPHOSPHATE DEHYDROGENASE)	4ix2	INOSINE-5'-MONOPHOSP HATE DEHYDROGENASE (Vibrio cholerae)	6 / 8	ASP A 250 SER A 251 SER A 252 ASN A 279 THR A 309 MET A 390	None None None IMP A 501 ( 4.4A) None None	0.82A	4fo4A-4ix2A: 57.3	4fo4A-4ix2A: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4FO4_A_MOAA502_1 (INOSINE 5'-MONOPHOSPHATE DEHYDROGENASE)	4ix2	INOSINE-5'-MONOPHOSP HATE DEHYDROGENASE (Vibrio cholerae)	6 / 8	SER A 251 SER A 252 ASN A 279 CYH A 307 THR A 309 MET A 390	None None IMP A 501 ( 4.4A) IMP A 501 (-4.9A) None None	0.46A	4fo4A-4ix2A: 57.3	4fo4A-4ix2A: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4FO4_B_MOAB502_1 (INOSINE 5'-MONOPHOSPHATE DEHYDROGENASE)	4ix2	INOSINE-5'-MONOPHOSP HATE DEHYDROGENASE (Vibrio cholerae)	7 / 8	SER A 251 SER A 252 ASN A 279 GLY A 302 CYH A 307 THR A 309 MET A 390	None None IMP A 501 ( 4.4A) None IMP A 501 (-4.9A) None None	0.43A	4fo4B-4ix2A: 57.2	4fo4B-4ix2A: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4FXS_A_MOAA702_1 (INOSINE-5'-MONOPHOSP HATE DEHYDROGENASE)	4ix2	INOSINE-5'-MONOPHOSP HATE DEHYDROGENASE (Vibrio cholerae)	9 / 9	ASP A 250 SER A 251 SER A 252 ASN A 279 ILE A 301 GLY A 302 CYH A 307 THR A 309 ASP A 340	None None None IMP A 501 ( 4.4A) None None IMP A 501 (-4.9A) None IMP A 501 (-2.3A)	0.53A	4fxsA-4ix2A: 55.8	4fxsA-4ix2A: 74.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KTV_A_ADNA403_1 (S-ADENOSYLMETHIONINE SYNTHASE ISOFORM TYPE-2)	4ix2	INOSINE-5'-MONOPHOSP HATE DEHYDROGENASE (Vibrio cholerae)	5 / 12	PRO A 373 SER A 364 SER A 305 ASP A 52 ILE A 306	None IMP A 501 (-2.8A) IMP A 501 (-2.2A) None None	1.45A	4ktvA-4ix2A: undetectable 4ktvB-4ix2A: undetectable	4ktvA-4ix2A: 23.62 4ktvB-4ix2A: 23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LG1_C_SAMC301_0 (PROTEIN-LYSINE METHYLTRANSFERASE METTL21D)	4ix2	INOSINE-5'-MONOPHOSP HATE DEHYDROGENASE (Vibrio cholerae)	5 / 12	ALA A 57 GLY A 223 LEU A 247 LEU A 239 ALA A 60	None	1.15A	4lg1C-4ix2A: undetectable	4lg1C-4ix2A: 20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OR0_A_NPSA603_1 (SERUM ALBUMIN)	4ix2	INOSINE-5'-MONOPHOSP HATE DEHYDROGENASE (Vibrio cholerae)	5 / 11	ARG A 441 LEU A 440 SER A 350 SER A 449 LEU A 32	None	1.22A	4or0A-4ix2A: undetectable	4or0A-4ix2A: 18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Q5M_A_ROCA1101_1 (PROTEASE)	4ix2	INOSINE-5'-MONOPHOSP HATE DEHYDROGENASE (Vibrio cholerae)	5 / 12	GLY A 278 ILE A 323 VAL A 246 ILE A 69 THR A 37	None	1.02A	4q5mA-4ix2A: undetectable	4q5mA-4ix2A: 19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QVW_K_BO2K301_1 (PROTEASOME SUBUNIT BETA TYPE-5 PROTEASOME SUBUNIT BETA TYPE-6)	4ix2	INOSINE-5'-MONOPHOSP HATE DEHYDROGENASE (Vibrio cholerae)	5 / 11	ALA A 281 ALA A 322 GLY A 254 GLY A 278 ASP A 340	None None None None IMP A 501 (-2.3A)	1.11A	4qvwK-4ix2A: undetectable 4qvwL-4ix2A: undetectable	4qvwK-4ix2A: 22.34 4qvwL-4ix2A: 20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QVW_Y_BO2Y301_1 (PROTEASOME SUBUNIT BETA TYPE-5 PROTEASOME SUBUNIT BETA TYPE-6)	4ix2	INOSINE-5'-MONOPHOSP HATE DEHYDROGENASE (Vibrio cholerae)	5 / 11	ALA A 281 ALA A 322 GLY A 254 GLY A 278 ASP A 340	None None None None IMP A 501 (-2.3A)	1.11A	4qvwY-4ix2A: undetectable 4qvwZ-4ix2A: undetectable	4qvwY-4ix2A: 22.34 4qvwZ-4ix2A: 20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QWU_Y_BO2Y301_1 (PROTEASOME SUBUNIT BETA TYPE-5 PROTEASOME SUBUNIT BETA TYPE-6)	4ix2	INOSINE-5'-MONOPHOSP HATE DEHYDROGENASE (Vibrio cholerae)	5 / 9	ALA A 281 ALA A 322 GLY A 254 GLY A 278 ASP A 340	None None None None IMP A 501 (-2.3A)	1.12A	4qwuY-4ix2A: undetectable 4qwuZ-4ix2A: undetectable	4qwuY-4ix2A: 22.61 4qwuZ-4ix2A: 20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5A06_B_SORB1342_0 (ALDOSE-ALDOSE OXIDOREDUCTASE)	4ix2	INOSINE-5'-MONOPHOSP HATE DEHYDROGENASE (Vibrio cholerae)	4 / 7	ILE A 69 LEU A 63 GLY A 67 GLY A 68	None	0.82A	5a06B-4ix2A: undetectable	5a06B-4ix2A: 23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5BYJ_A_OQRA302_0 (SULFOTRANSFERASE)	4ix2	INOSINE-5'-MONOPHOSP HATE DEHYDROGENASE (Vibrio cholerae)	5 / 12	MET A 437 ILE A 433 LEU A 440 VAL A 360 GLY A 70	None	1.13A	5byjA-4ix2A: undetectable	5byjA-4ix2A: 20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JGL_B_SAMB301_0 (UBIE/COQ5 FAMILY METHYLTRANSFERASE, PUTATIVE)	4ix2	INOSINE-5'-MONOPHOSP HATE DEHYDROGENASE (Vibrio cholerae)	5 / 12	THR A 29 ALA A 459 ALA A 450 GLY A 448 PRO A 20	None	1.40A	5jglB-4ix2A: undetectable	5jglB-4ix2A: 21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X6Y_C_SAMC901_0 (MRNA CAPPING ENZYME P5)	4ix2	INOSINE-5'-MONOPHOSP HATE DEHYDROGENASE (Vibrio cholerae)	5 / 11	VAL A 25 GLY A 445 ASP A 454 ALA A 450 SER A 23	None	1.22A	5x6yC-4ix2A: undetectable	5x6yC-4ix2A: 16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6CLX_A_SAMA401_0 (O-METHYLTRANSFERASE)	4ix2	INOSINE-5'-MONOPHOSP HATE DEHYDROGENASE (Vibrio cholerae)	5 / 12	ASP A 348 ALA A 357 GLY A 341 ARG A 344 VAL A 299	None None IMP A 501 ( 3.8A) None None	1.27A	6clxA-4ix2A: undetectable	6clxA-4ix2A: 26.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6GQI_A_ACTA604_0 (CYCLOHEXANONE MONOOXYGENASE FROM THERMOCRISPUM MUNICIPALE)	4ix2	INOSINE-5'-MONOPHOSP HATE DEHYDROGENASE (Vibrio cholerae)	4 / 6	PRO A 45 ILE A 433 GLY A 68 GLU A 66	None	1.06A	6gqiA-4ix2A: undetectable	6gqiA-4ix2A: 23.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6HWD_K_BO2K301_0 (PROTEASOME SUBUNIT BETA TYPE-5 PROTEASOME SUBUNIT BETA TYPE-6)	4ix2	INOSINE-5'-MONOPHOSP HATE DEHYDROGENASE (Vibrio cholerae)	6 / 11	ALA A 281 THR A 282 ALA A 326 ALA A 322 GLY A 254 GLY A 278	None	1.13A	6hwdK-4ix2A: undetectable 6hwdL-4ix2A: undetectable	6hwdK-4ix2A: 15.36 6hwdL-4ix2A: 11.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6HWD_Y_BO2Y301_0 (PROTEASOME SUBUNIT BETA TYPE-5 PROTEASOME SUBUNIT BETA TYPE-6)	4ix2	INOSINE-5'-MONOPHOSP HATE DEHYDROGENASE (Vibrio cholerae)	6 / 11	ALA A 281 THR A 282 ALA A 326 ALA A 322 GLY A 254 GLY A 278	None	1.13A	6hwdY-4ix2A: undetectable 6hwdZ-4ix2A: undetectable	6hwdY-4ix2A: 15.36 6hwdZ-4ix2A: 11.60

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1HBP_A_RTLA184_0","RETINOL BINDING PROTEIN","4ix2","INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE","Vibrio cholerae",5,"PHE A 461;ALA A 354;ALA A 352;VAL A 362;GLN A 436","None;None;None;IMP A 501 (-4.4A);None","1.18A","1hbpA-4ix2A:undetectable","1hbpA-4ix2A:17.84"],["1JR1_A_MOAA1332_1","INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE 2","4ix2","INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE","Vibrio cholerae",6,"ASP A 250;SER A 251;ASN A 279;GLY A 302;CYH A 307;THR A 309","None;None;IMP A 501 ( 4.4A);None;IMP A 501 (-4.9A);None","0.95A","1jr1A-4ix2A:49.0","1jr1A-4ix2A:32.36"],["1JR1_A_MOAA1332_1","INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE 2","4ix2","INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE","Vibrio cholerae",6,"ASP A 250;SER A 252;ASN A 279;GLY A 302;CYH A 307;THR A 309","None;None;IMP A 501 ( 4.4A);None;IMP A 501 (-4.9A);None","0.79A","1jr1A-4ix2A:49.0","1jr1A-4ix2A:32.36"],["1JR1_B_MOAB1333_1","INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE 2","4ix2","INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE","Vibrio cholerae",4,"ASP A 250;ASN A 279;GLY A 302;THR A 309","None;IMP A 501 ( 4.4A);None;None","0.60A","1jr1B-4ix2A:48.7","1jr1B-4ix2A:32.36"],["1JR1_B_MOAB1333_1","INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE 2","4ix2","INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE","Vibrio cholerae",4,"ASP A 250;SER A 252;ASN A 279;GLY A 302","None;None;IMP A 501 ( 4.4A);None","0.87A","1jr1B-4ix2A:48.7","1jr1B-4ix2A:32.36"],["1ME7_A_MOAA600_1","INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE","4ix2","INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE","Vibrio cholerae",6,"ASP A 250;SER A 251;SER A 252;ILE A 301;GLY A 302;CYH A 307","None;None;None;None;None;IMP A 501 (-4.9A)","0.85A","1me7A-4ix2A:45.7","1me7A-4ix2A:31.24"],["1ME7_A_MOAA600_1","INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE","4ix2","INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE","Vibrio cholerae",6,"SER A 251;SER A 252;ASN A 279;ILE A 301;GLY A 302;CYH A 307","None;None;IMP A 501 ( 4.4A);None;None;IMP A 501 (-4.9A)","0.61A","1me7A-4ix2A:45.7","1me7A-4ix2A:31.24"],["1MEH_A_MOAA600_1","INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE","4ix2","INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE","Vibrio cholerae",6,"ASP A 250;SER A 251;SER A 252;ASN A 279;ILE A 301;GLY A 302","None;None;None;IMP A 501 ( 4.4A);None;None","0.80A","1mehA-4ix2A:44.4","1mehA-4ix2A:31.24"],["1MEI_A_MOAA600_1","INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE","4ix2","INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE","Vibrio cholerae",5,"ASP A 250;SER A 251;SER A 252;ASN A 279;ILE A 301","None;None;None;IMP A 501 ( 4.4A);None","0.83A","1meiA-4ix2A:45.5","1meiA-4ix2A:31.24"],["1RBP_A_RTLA183_0","PLASMA RETINOL-BINDING PROTEIN PRECURSOR","4ix2","INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE","Vibrio cholerae",5,"ALA A 355;PHE A 461;ALA A 352;VAL A 362;GLN A 436","None;None;None;IMP A 501 (-4.4A);None","1.36A","1rbpA-4ix2A:undetectable","1rbpA-4ix2A:17.17"],["1RXC_B_URFB2011_1","URIDINE PHOSPHORYLASE","4ix2","INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE","Vibrio cholerae",4,"THR A 266;GLY A 293;ILE A 275;VAL A 294","None","0.95A","1rxcB-4ix2A:undetectable","1rxcB-4ix2A:24.73"],["1RXC_E_URFE2031_1","URIDINE PHOSPHORYLASE","4ix2","INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE","Vibrio cholerae",4,"THR A 266;GLY A 293;ILE A 275;VAL A 294","None","0.99A","1rxcE-4ix2A:undetectable","1rxcE-4ix2A:24.73"],["1RXC_I_URFI2041_1","URIDINE PHOSPHORYLASE","4ix2","INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE","Vibrio cholerae",4,"THR A 266;GLY A 293;ILE A 275;VAL A 294","None","0.93A","1rxcI-4ix2A:undetectable","1rxcI-4ix2A:24.73"],["1RXC_K_URFK2061_1","URIDINE PHOSPHORYLASE","4ix2","INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE","Vibrio cholerae",4,"THR A 266;GLY A 293;ILE A 275;VAL A 294","None","0.97A","1rxcK-4ix2A:undetectable","1rxcK-4ix2A:24.73"],["1SG9_C_SAMC303_0","HEMK PROTEIN","4ix2","INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE","Vibrio cholerae",5,"ILE A 276;GLY A 254;ALA A 288;SER A 252;ALA A 228","None","1.12A","1sg9C-4ix2A:undetectable","1sg9C-4ix2A:23.48"],["1ZQ9_A_SAMA4000_0","PROBABLE DIMETHYLADENOSINE TRANSFERASE","4ix2","INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE","Vibrio cholerae",5,"ILE A  44;GLY A  68;LEU A  63;VAL A 246;ILE A 276","None","1.18A","1zq9A-4ix2A:undetectable","1zq9A-4ix2A:21.08"],["2F8L_A_SAMA400_0","HYPOTHETICAL PROTEIN LMO1582","4ix2","INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE","Vibrio cholerae",5,"ASN A  43;LEU A  32;VAL A 337;LEU A  36;GLY A 356","None","1.12A","2f8lA-4ix2A:undetectable","2f8lA-4ix2A:23.25"],["2RDD_A_AICA1110_1","ACRIFLAVINE RESISTANCE PROTEIN B","4ix2","INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE","Vibrio cholerae",4,"LYS A 385;ALA A 367;PHE A 366;GLY A 363","None;None;None;IMP A 501 (-3.5A)","1.38A","2rddA-4ix2A:undetectable","2rddA-4ix2A:17.63"],["2VE3_B_REAB1445_1","PUTATIVE CYTOCHROME P450 120","4ix2","INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE","Vibrio cholerae",5,"ALA A 286;THR A 321;VAL A 317;GLY A 316;PRO A 303","None","1.20A","2ve3B-4ix2A:undetectable","2ve3B-4ix2A:20.69"],["3ZMD_A_SALA201_1","PUTATIVE TRANSCRIPTIONAL REGULATOR;PUTATIVE TRANSCRIPTIONAL REGULATOR","4ix2","INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE","Vibrio cholerae",4,"ARG A  33;LEU A  32;ARG A 441;MET A 444","None","1.44A","3zmdA-4ix2A:undetectable;3zmdB-4ix2A:undetectable","3zmdA-4ix2A:19.28;3zmdB-4ix2A:19.28"],["4AF0_A_MOAA1526_1","INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE","4ix2","INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE","Vibrio cholerae",4,"ASP A 250;SER A 251;SER A 252;ASN A 279","None;None;None;IMP A 501 ( 4.4A)","0.74A","4af0A-4ix2A:45.8","4af0A-4ix2A:31.39"],["4AF0_B_MOAB1526_1","INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE","4ix2","INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE","Vibrio cholerae",5,"ASP A 250;SER A 251;SER A 252;ASN A 279;MET A 390","None;None;None;IMP A 501 ( 4.4A);None","0.80A","4af0B-4ix2A:45.7","4af0B-4ix2A:31.06"],["4DTZ_A_LDPA501_1","CYTOCHROME P450 BM3 VARIANT 8C8","4ix2","INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE","Vibrio cholerae",4,"ALA A 296;PRO A 336;LEU A  36;THR A  37","None","0.94A","4dtzA-4ix2A:undetectable","4dtzA-4ix2A:21.50"],["4DU2_B_LDPB501_1","CYTOCHROME P450 BM3 VARIANT B7","4ix2","INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE","Vibrio cholerae",4,"ALA A 296;PRO A 336;LEU A  36;THR A  37","None","0.89A","4du2B-4ix2A:undetectable","4du2B-4ix2A:21.22"],["4FO4_A_MOAA502_1","INOSINE 5'-MONOPHOSPHATE DEHYDROGENASE","4ix2","INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE","Vibrio cholerae",6,"ASP A 250;SER A 251;SER A 252;ASN A 279;THR A 309;MET A 390","None;None;None;IMP A 501 ( 4.4A);None;None","0.82A","4fo4A-4ix2A:57.3","4fo4A-4ix2A:100.00"],["4FO4_A_MOAA502_1","INOSINE 5'-MONOPHOSPHATE DEHYDROGENASE","4ix2","INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE","Vibrio cholerae",6,"SER A 251;SER A 252;ASN A 279;CYH A 307;THR A 309;MET A 390","None;None;IMP A 501 ( 4.4A);IMP A 501 (-4.9A);None;None","0.46A","4fo4A-4ix2A:57.3","4fo4A-4ix2A:100.00"],["4FO4_B_MOAB502_1","INOSINE 5'-MONOPHOSPHATE DEHYDROGENASE","4ix2","INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE","Vibrio cholerae",7,"SER A 251;SER A 252;ASN A 279;GLY A 302;CYH A 307;THR A 309;MET A 390","None;None;IMP A 501 ( 4.4A);None;IMP A 501 (-4.9A);None;None","0.43A","4fo4B-4ix2A:57.2","4fo4B-4ix2A:100.00"],["4FXS_A_MOAA702_1","INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE","4ix2","INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE","Vibrio cholerae",9,"ASP A 250;SER A 251;SER A 252;ASN A 279;ILE A 301;GLY A 302;CYH A 307;THR A 309;ASP A 340","None;None;None;IMP A 501 ( 4.4A);None;None;IMP A 501 (-4.9A);None;IMP A 501 (-2.3A)","0.53A","4fxsA-4ix2A:55.8","4fxsA-4ix2A:74.03"],["4KTV_A_ADNA403_1","S-ADENOSYLMETHIONINE SYNTHASE ISOFORM TYPE-2;S-ADENOSYLMETHIONINE SYNTHASE ISOFORM TYPE-2","4ix2","INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE","Vibrio cholerae",5,"PRO A 373;SER A 364;SER A 305;ASP A  52;ILE A 306","None;IMP A 501 (-2.8A);IMP A 501 (-2.2A);None;None","1.45A","4ktvA-4ix2A:undetectable;4ktvB-4ix2A:undetectable","4ktvA-4ix2A:23.62;4ktvB-4ix2A:23.62"],["4LG1_C_SAMC301_0","PROTEIN-LYSINE METHYLTRANSFERASE METTL21D","4ix2","INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE","Vibrio cholerae",5,"ALA A  57;GLY A 223;LEU A 247;LEU A 239;ALA A  60","None","1.15A","4lg1C-4ix2A:undetectable","4lg1C-4ix2A:20.58"],["4OR0_A_NPSA603_1","SERUM ALBUMIN","4ix2","INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE","Vibrio cholerae",5,"ARG A 441;LEU A 440;SER A 350;SER A 449;LEU A  32","None","1.22A","4or0A-4ix2A:undetectable","4or0A-4ix2A:18.98"],["4Q5M_A_ROCA1101_1","PROTEASE","4ix2","INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE","Vibrio cholerae",5,"GLY A 278;ILE A 323;VAL A 246;ILE A  69;THR A  37","None","1.02A","4q5mA-4ix2A:undetectable","4q5mA-4ix2A:19.47"],["4QVW_K_BO2K301_1","PROTEASOME SUBUNIT BETA TYPE-5;PROTEASOME SUBUNIT BETA TYPE-6","4ix2","INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE","Vibrio cholerae",5,"ALA A 281;ALA A 322;GLY A 254;GLY A 278;ASP A 340","None;None;None;None;IMP A 501 (-2.3A)","1.11A","4qvwK-4ix2A:undetectable;4qvwL-4ix2A:undetectable","4qvwK-4ix2A:22.34;4qvwL-4ix2A:20.05"],["4QVW_Y_BO2Y301_1","PROTEASOME SUBUNIT BETA TYPE-5;PROTEASOME SUBUNIT BETA TYPE-6","4ix2","INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE","Vibrio cholerae",5,"ALA A 281;ALA A 322;GLY A 254;GLY A 278;ASP A 340","None;None;None;None;IMP A 501 (-2.3A)","1.11A","4qvwY-4ix2A:undetectable;4qvwZ-4ix2A:undetectable","4qvwY-4ix2A:22.34;4qvwZ-4ix2A:20.05"],["4QWU_Y_BO2Y301_1","PROTEASOME SUBUNIT BETA TYPE-5;PROTEASOME SUBUNIT BETA TYPE-6","4ix2","INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE","Vibrio cholerae",5,"ALA A 281;ALA A 322;GLY A 254;GLY A 278;ASP A 340","None;None;None;None;IMP A 501 (-2.3A)","1.12A","4qwuY-4ix2A:undetectable;4qwuZ-4ix2A:undetectable","4qwuY-4ix2A:22.61;4qwuZ-4ix2A:20.05"],["5A06_B_SORB1342_0","ALDOSE-ALDOSE OXIDOREDUCTASE","4ix2","INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE","Vibrio cholerae",4,"ILE A  69;LEU A  63;GLY A  67;GLY A  68","None","0.82A","5a06B-4ix2A:undetectable","5a06B-4ix2A:23.59"],["5BYJ_A_OQRA302_0","SULFOTRANSFERASE","4ix2","INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE","Vibrio cholerae",5,"MET A 437;ILE A 433;LEU A 440;VAL A 360;GLY A  70","None","1.13A","5byjA-4ix2A:undetectable","5byjA-4ix2A:20.78"],["5JGL_B_SAMB301_0","UBIE\/COQ5 FAMILY METHYLTRANSFERASE, PUTATIVE","4ix2","INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE","Vibrio cholerae",5,"THR A  29;ALA A 459;ALA A 450;GLY A 448;PRO A  20","None","1.40A","5jglB-4ix2A:undetectable","5jglB-4ix2A:21.32"],["5X6Y_C_SAMC901_0","MRNA CAPPING ENZYME P5","4ix2","INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE","Vibrio cholerae",5,"VAL A  25;GLY A 445;ASP A 454;ALA A 450;SER A  23","None","1.22A","5x6yC-4ix2A:undetectable","5x6yC-4ix2A:16.67"],["6CLX_A_SAMA401_0","O-METHYLTRANSFERASE","4ix2","INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE","Vibrio cholerae",5,"ASP A 348;ALA A 357;GLY A 341;ARG A 344;VAL A 299","None;None;IMP A 501 ( 3.8A);None;None","1.27A","6clxA-4ix2A:undetectable","6clxA-4ix2A:26.72"],["6GQI_A_ACTA604_0","CYCLOHEXANONE MONOOXYGENASE FROM THERMOCRISPUM MUNICIPALE","4ix2","INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE","Vibrio cholerae",4,"PRO A  45;ILE A 433;GLY A  68;GLU A  66","None","1.06A","6gqiA-4ix2A:undetectable","6gqiA-4ix2A:23.41"],["6HWD_K_BO2K301_0","PROTEASOME SUBUNIT BETA TYPE-5;PROTEASOME SUBUNIT BETA TYPE-6","4ix2","INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE","Vibrio cholerae",6,"ALA A 281;THR A 282;ALA A 326;ALA A 322;GLY A 254;GLY A 278","None","1.13A","6hwdK-4ix2A:undetectable;6hwdL-4ix2A:undetectable","6hwdK-4ix2A:15.36;6hwdL-4ix2A:11.60"],["6HWD_Y_BO2Y301_0","PROTEASOME SUBUNIT BETA TYPE-5;PROTEASOME SUBUNIT BETA TYPE-6","4ix2","INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE","Vibrio cholerae",6,"ALA A 281;THR A 282;ALA A 326;ALA A 322;GLY A 254;GLY A 278","None","1.13A","6hwdY-4ix2A:undetectable;6hwdZ-4ix2A:undetectable","6hwdY-4ix2A:15.36;6hwdZ-4ix2A:11.60"]]