SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ix9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_G_CHDG1085_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 6A2
CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)
4ix9 V-TYPE PROTON ATPASE
SUBUNIT F

(Saccharomyces
cerevisiae)
5 / 10 ARG A  61
PHE A  38
GLY A  26
THR A  16
THR A  18
None
None
TRS  A 101 (-3.5A)
None
None
1.43A 2y69G-4ix9A:
undetectable
2y69N-4ix9A:
undetectable
2y69O-4ix9A:
undetectable
2y69G-4ix9A:
22.73
2y69N-4ix9A:
10.32
2y69O-4ix9A:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_G_CHDG86_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 6A2
CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)
4ix9 V-TYPE PROTON ATPASE
SUBUNIT F

(Saccharomyces
cerevisiae)
5 / 11 ARG A  61
PHE A  38
GLY A  26
THR A  16
THR A  18
None
None
TRS  A 101 (-3.5A)
None
None
1.48A 2zxwG-4ix9A:
undetectable
2zxwN-4ix9A:
undetectable
2zxwO-4ix9A:
undetectable
2zxwG-4ix9A:
19.59
2zxwN-4ix9A:
10.32
2zxwO-4ix9A:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_B_CHDB1085_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)
4ix9 V-TYPE PROTON ATPASE
SUBUNIT F

(Saccharomyces
cerevisiae)
5 / 11 GLY A  26
THR A  16
THR A  18
ARG A  61
PHE A  38
TRS  A 101 (-3.5A)
None
None
None
None
1.47A 3asoA-4ix9A:
undetectable
3asoB-4ix9A:
undetectable
3asoT-4ix9A:
undetectable
3asoA-4ix9A:
10.32
3asoB-4ix9A:
18.72
3asoT-4ix9A:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_B_CHDB303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)
4ix9 V-TYPE PROTON ATPASE
SUBUNIT F

(Saccharomyces
cerevisiae)
5 / 11 GLY A  26
THR A  16
THR A  18
ARG A  61
PHE A  38
TRS  A 101 (-3.5A)
None
None
None
None
1.47A 3wg7A-4ix9A:
undetectable
3wg7B-4ix9A:
undetectable
3wg7T-4ix9A:
undetectable
3wg7A-4ix9A:
10.32
3wg7B-4ix9A:
18.72
3wg7T-4ix9A:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_G_CHDG103_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)
4ix9 V-TYPE PROTON ATPASE
SUBUNIT F

(Saccharomyces
cerevisiae)
5 / 10 ARG A  61
PHE A  38
GLY A  26
THR A  16
THR A  18
None
None
TRS  A 101 (-3.5A)
None
None
1.46A 3wg7G-4ix9A:
undetectable
3wg7N-4ix9A:
undetectable
3wg7O-4ix9A:
undetectable
3wg7G-4ix9A:
19.59
3wg7N-4ix9A:
10.32
3wg7O-4ix9A:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JTP_A_ASCA802_0
(RRNA N-GLYCOSIDASE)
4ix9 V-TYPE PROTON ATPASE
SUBUNIT F

(Saccharomyces
cerevisiae)
4 / 5 ILE A  77
ASN A  70
TYR A  40
ILE A  50
None
1.01A 4jtpA-4ix9A:
undetectable
4jtpA-4ix9A:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)
4ix9 V-TYPE PROTON ATPASE
SUBUNIT F

(Saccharomyces
cerevisiae)
4 / 6 GLU A  60
ARG A  61
ASP A  63
ARG A   5
None
1.13A 4kcnB-4ix9A:
undetectable
4kcnB-4ix9A:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGF_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)
4ix9 V-TYPE PROTON ATPASE
SUBUNIT F

(Saccharomyces
cerevisiae)
4 / 6 THR A  29
GLU A  31
THR A  32
LEU A   7
None
None
None
TRS  A 101 (-3.6A)
0.95A 4pgfA-4ix9A:
undetectable
4pgfA-4ix9A:
13.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_B_CHDB303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)
4ix9 V-TYPE PROTON ATPASE
SUBUNIT F

(Saccharomyces
cerevisiae)
5 / 11 GLY A  26
THR A  16
THR A  18
ARG A  61
PHE A  38
TRS  A 101 (-3.5A)
None
None
None
None
1.47A 5b1aA-4ix9A:
undetectable
5b1aB-4ix9A:
undetectable
5b1aT-4ix9A:
undetectable
5b1aA-4ix9A:
10.32
5b1aB-4ix9A:
18.72
5b1aT-4ix9A:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_O_CHDO302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)
4ix9 V-TYPE PROTON ATPASE
SUBUNIT F

(Saccharomyces
cerevisiae)
5 / 10 ARG A  61
PHE A  38
GLY A  26
THR A  16
THR A  18
None
None
TRS  A 101 (-3.5A)
None
None
1.45A 5b1aG-4ix9A:
undetectable
5b1aN-4ix9A:
undetectable
5b1aO-4ix9A:
undetectable
5b1aG-4ix9A:
19.59
5b1aN-4ix9A:
10.32
5b1aO-4ix9A:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_B_CHDB303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)
4ix9 V-TYPE PROTON ATPASE
SUBUNIT F

(Saccharomyces
cerevisiae)
5 / 10 GLY A  26
THR A  16
THR A  18
ARG A  61
PHE A  38
TRS  A 101 (-3.5A)
None
None
None
None
1.46A 5wauA-4ix9A:
undetectable
5wauB-4ix9A:
undetectable
5waug-4ix9A:
undetectable
5wauA-4ix9A:
10.32
5wauB-4ix9A:
18.72
5waug-4ix9A:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_B_CHDB302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)
4ix9 V-TYPE PROTON ATPASE
SUBUNIT F

(Saccharomyces
cerevisiae)
5 / 11 GLY A  26
THR A  16
THR A  18
ARG A  61
PHE A  38
TRS  A 101 (-3.5A)
None
None
None
None
1.46A 5x19A-4ix9A:
undetectable
5x19B-4ix9A:
undetectable
5x19T-4ix9A:
undetectable
5x19A-4ix9A:
10.32
5x19B-4ix9A:
18.72
5x19T-4ix9A:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_B_CHDB304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)
4ix9 V-TYPE PROTON ATPASE
SUBUNIT F

(Saccharomyces
cerevisiae)
5 / 11 GLY A  26
THR A  16
THR A  18
ARG A  61
PHE A  38
TRS  A 101 (-3.5A)
None
None
None
None
1.44A 5xdqA-4ix9A:
undetectable
5xdqB-4ix9A:
undetectable
5xdqT-4ix9A:
undetectable
5xdqA-4ix9A:
10.32
5xdqB-4ix9A:
18.72
5xdqT-4ix9A:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_G_CHDG102_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)
4ix9 V-TYPE PROTON ATPASE
SUBUNIT F

(Saccharomyces
cerevisiae)
5 / 10 ARG A  61
PHE A  38
GLY A  26
THR A  16
THR A  18
None
None
TRS  A 101 (-3.5A)
None
None
1.45A 5xdqG-4ix9A:
undetectable
5xdqN-4ix9A:
undetectable
5xdqO-4ix9A:
undetectable
5xdqG-4ix9A:
19.59
5xdqN-4ix9A:
10.32
5xdqO-4ix9A:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_B_CHDB302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)
4ix9 V-TYPE PROTON ATPASE
SUBUNIT F

(Saccharomyces
cerevisiae)
5 / 11 GLY A  26
THR A  16
THR A  18
ARG A  61
PHE A  38
TRS  A 101 (-3.5A)
None
None
None
None
1.44A 5xdxA-4ix9A:
undetectable
5xdxB-4ix9A:
undetectable
5xdxT-4ix9A:
undetectable
5xdxA-4ix9A:
10.32
5xdxB-4ix9A:
18.72
5xdxT-4ix9A:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_O_CHDO301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)
4ix9 V-TYPE PROTON ATPASE
SUBUNIT F

(Saccharomyces
cerevisiae)
5 / 10 ARG A  61
PHE A  38
GLY A  26
THR A  16
THR A  18
None
None
TRS  A 101 (-3.5A)
None
None
1.45A 5xdxG-4ix9A:
undetectable
5xdxN-4ix9A:
undetectable
5xdxO-4ix9A:
undetectable
5xdxG-4ix9A:
19.59
5xdxN-4ix9A:
10.32
5xdxO-4ix9A:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_B_CHDB302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)
4ix9 V-TYPE PROTON ATPASE
SUBUNIT F

(Saccharomyces
cerevisiae)
5 / 11 GLY A  26
THR A  16
THR A  18
ARG A  61
PHE A  38
TRS  A 101 (-3.5A)
None
None
None
None
1.45A 5zcoA-4ix9A:
undetectable
5zcoB-4ix9A:
undetectable
5zcoT-4ix9A:
undetectable
5zcoA-4ix9A:
10.32
5zcoB-4ix9A:
18.72
5zcoT-4ix9A:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_G_CHDG102_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)
4ix9 V-TYPE PROTON ATPASE
SUBUNIT F

(Saccharomyces
cerevisiae)
5 / 10 ARG A  61
PHE A  38
GLY A  26
THR A  16
THR A  18
None
None
TRS  A 101 (-3.5A)
None
None
1.42A 5zcoG-4ix9A:
undetectable
5zcoN-4ix9A:
undetectable
5zcoO-4ix9A:
undetectable
5zcoG-4ix9A:
19.59
5zcoN-4ix9A:
10.32
5zcoO-4ix9A:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_B_CHDB301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)
4ix9 V-TYPE PROTON ATPASE
SUBUNIT F

(Saccharomyces
cerevisiae)
5 / 11 GLY A  26
THR A  16
THR A  18
ARG A  61
PHE A  38
TRS  A 101 (-3.5A)
None
None
None
None
1.46A 5zcpA-4ix9A:
undetectable
5zcpB-4ix9A:
undetectable
5zcpT-4ix9A:
undetectable
5zcpA-4ix9A:
10.32
5zcpB-4ix9A:
18.72
5zcpT-4ix9A:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_G_CHDG102_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)
4ix9 V-TYPE PROTON ATPASE
SUBUNIT F

(Saccharomyces
cerevisiae)
5 / 10 ARG A  61
PHE A  38
GLY A  26
THR A  16
THR A  18
None
None
TRS  A 101 (-3.5A)
None
None
1.44A 5zcpG-4ix9A:
undetectable
5zcpN-4ix9A:
undetectable
5zcpO-4ix9A:
undetectable
5zcpG-4ix9A:
19.59
5zcpN-4ix9A:
10.32
5zcpO-4ix9A:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C06_D_FI8D1404_0
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA
DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')
4ix9 V-TYPE PROTON ATPASE
SUBUNIT F

(Saccharomyces
cerevisiae)
4 / 8 ILE A  50
THR A  51
THR A  58
SER A  83
None
1.09A 6c06C-4ix9A:
undetectable
6c06C-4ix9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_B_CHDB304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)
4ix9 V-TYPE PROTON ATPASE
SUBUNIT F

(Saccharomyces
cerevisiae)
5 / 11 GLY A  26
THR A  16
THR A  18
ARG A  61
PHE A  38
TRS  A 101 (-3.5A)
None
None
None
None
1.45A 6nknA-4ix9A:
undetectable
6nknB-4ix9A:
undetectable
6nknT-4ix9A:
undetectable
6nknA-4ix9A:
10.32
6nknB-4ix9A:
18.72
6nknT-4ix9A:
19.59