SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4iy9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJG_B_ADNB1502_1
(235AA LONG
HYPOTHETICAL
BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 4iy9 30K PROTEIN 1
(Bombyx
mori) 		4 / 7 LYS A 186
ASN A  53
PRO A 184
ALA A 185
 None
 1.49A 2ejgB-4iy9A:
undetectable		 2ejgB-4iy9A:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2N_C_X2NC1479_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 4iy9 30K PROTEIN 1
(Bombyx
mori) 		5 / 12 PHE A 193
PRO A 184
VAL A 191
ALA A 133
MET A  58
 None
 1.27A 2x2nC-4iy9A:
undetectable		 2x2nC-4iy9A:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_A_SPMA201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 4iy9 30K PROTEIN 1
(Bombyx
mori) 		4 / 6 ASN A  44
TYR A  15
GLU A  11
GLU A  12
 None
 1.50A 4mi4A-4iy9A:
undetectable		 4mi4A-4iy9A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5Q_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 4iy9 30K PROTEIN 1
(Bombyx
mori) 		4 / 6 ASP A 121
ALA A 100
LYS A  91
THR A 102
 None
 1.37A 4w5qA-4iy9A:
undetectable		 4w5qA-4iy9A:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5R_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 4iy9 30K PROTEIN 1
(Bombyx
mori) 		4 / 6 ASP A 121
ALA A 100
LYS A  91
THR A 102
 None
 1.31A 4w5rA-4iy9A:
undetectable		 4w5rA-4iy9A:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5T_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 4iy9 30K PROTEIN 1
(Bombyx
mori) 		4 / 6 ASP A 121
ALA A 100
LYS A  91
THR A 102
 None
 1.34A 4w5tA-4iy9A:
undetectable		 4w5tA-4iy9A:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WW7_A_ACTA305_0
(EKC/KEOPS COMPLEX
SUBUNIT BUD32)		 4iy9 30K PROTEIN 1
(Bombyx
mori) 		4 / 6 LEU A  10
LEU A  14
GLU A  11
ILE A  42
 None
 0.97A 4ww7A-4iy9A:
undetectable		 4ww7A-4iy9A:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y1D_D_DVAD5_0
(CYCLIC HEXAPEPTIDE
CYC[NDPOPPKID]
INTEGRASE)		 4iy9 30K PROTEIN 1
(Bombyx
mori) 		3 / 3 GLU A  11
LYS A  48
ASN A  44
 None
 0.99A 4y1dA-4iy9A:
undetectable
4y1dD-4iy9A:
undetectable		 4y1dA-4iy9A:
19.59
4y1dD-4iy9A:
7.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA906_0
(PROTEIN ARGONAUTE-2)		 4iy9 30K PROTEIN 1
(Bombyx
mori) 		4 / 6 ASP A 121
ALA A 100
LYS A  91
THR A 102
 None
 1.30A 4z4cA-4iy9A:
undetectable		 4z4cA-4iy9A:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4F_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 4iy9 30K PROTEIN 1
(Bombyx
mori) 		4 / 6 ASP A 121
ALA A 100
LYS A  91
THR A 102
 None
 1.36A 4z4fA-4iy9A:
undetectable		 4z4fA-4iy9A:
12.11