SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ize'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_E_SVRE510_2
(PHOSPHOLIPASE A2)		 4ize INTERLEUKIN-36 GAMMA
(Homo
sapiens) 		4 / 6 LYS A 103
GLN A 102
GLY A  78
LEU A  42
 None
 1.04A 3bjwE-4izeA:
undetectable		 3bjwE-4izeA:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_B_CE3B302_2
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 4ize INTERLEUKIN-36 GAMMA
(Homo
sapiens) 		3 / 3 CYH A  85
PRO A 116
ASP A 106
 None
 1.02A 3hlwB-4izeA:
undetectable		 3hlwB-4izeA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_H_CVIH301_1
(REGULATORY PROTEIN
TETR)		 4ize INTERLEUKIN-36 GAMMA
(Homo
sapiens) 		4 / 8 GLY A  25
ILE A  27
GLN A  32
ASP A 169
 None
 0.90A 5vlmH-4izeA:
undetectable		 5vlmH-4izeA:
20.49