SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4izg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1E7B_A_HLTA4002_1 (SERUM ALBUMIN)	4izg	MANDELATE RACEMASE/MUCONATE LACTONIZING ENZYME, N-TERMINAL DOMAIN PROTEIN (Paracoccus denitrificans)	4 / 4	ARG A 119 ALA A 121 ALA A 128 GLU A 130	None	1.05A	1e7bA-4izgA: undetectable	1e7bA-4izgA: 20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1JIP_A_KTNA801_1 (CYTOCHROME P450 107A1)	4izg	MANDELATE RACEMASE/MUCONATE LACTONIZING ENZYME, N-TERMINAL DOMAIN PROTEIN (Paracoccus denitrificans)	5 / 12	PHE A 279 ALA A 277 LEU A 123 ALA A 108 LEU A 124	None	1.35A	1jipA-4izgA: undetectable	1jipA-4izgA: 23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KQE_A_DVAA6_0 (MINI-GRAMICIDIN A)	4izg	MANDELATE RACEMASE/MUCONATE LACTONIZING ENZYME, N-TERMINAL DOMAIN PROTEIN (Paracoccus denitrificans)	3 / 3	ALA A 328 VAL A 15 TRP A 296	None	0.86A	1kqeA-4izgA: undetectable 1kqeE-4izgA: undetectable	1kqeA-4izgA: 5.59 1kqeE-4izgA: 5.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KQE_B_DVAB6_0 (MINI-GRAMICIDIN A)	4izg	MANDELATE RACEMASE/MUCONATE LACTONIZING ENZYME, N-TERMINAL DOMAIN PROTEIN (Paracoccus denitrificans)	3 / 3	ALA A 328 VAL A 15 TRP A 296	None	0.85A	1kqeB-4izgA: undetectable 1kqeD-4izgA: undetectable	1kqeB-4izgA: 5.59 1kqeD-4izgA: 5.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KQE_D_DVAD6_0 (MINI-GRAMICIDIN A)	4izg	MANDELATE RACEMASE/MUCONATE LACTONIZING ENZYME, N-TERMINAL DOMAIN PROTEIN (Paracoccus denitrificans)	3 / 3	TRP A 296 ALA A 328 VAL A 15	None	0.87A	1kqeB-4izgA: undetectable 1kqeD-4izgA: undetectable	1kqeB-4izgA: 5.59 1kqeD-4izgA: 5.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KQE_E_DVAE6_0 (MINI-GRAMICIDIN A)	4izg	MANDELATE RACEMASE/MUCONATE LACTONIZING ENZYME, N-TERMINAL DOMAIN PROTEIN (Paracoccus denitrificans)	3 / 3	TRP A 296 ALA A 328 VAL A 15	None	0.86A	1kqeA-4izgA: undetectable 1kqeE-4izgA: undetectable	1kqeA-4izgA: 5.59 1kqeE-4izgA: 5.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1SGU_B_MK1B2632_2 (POL POLYPROTEIN)	4izg	MANDELATE RACEMASE/MUCONATE LACTONIZING ENZYME, N-TERMINAL DOMAIN PROTEIN (Paracoccus denitrificans)	5 / 12	GLY A 271 ALA A 102 ASP A 105 ILE A 301 ALA A 295	None None None None 4OP A 416 (-4.0A)	1.02A	1sguB-4izgA: undetectable	1sguB-4izgA: 13.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BUE_A_RIOA1201_0 (AAC(6')-IB)	4izg	MANDELATE RACEMASE/MUCONATE LACTONIZING ENZYME, N-TERMINAL DOMAIN PROTEIN (Paracoccus denitrificans)	5 / 11	TRP A 321 TYR A 326 TYR A 56 SER A 24 ASP A 242	4OP A 416 ( 3.8A) None 4OP A 416 (-4.4A) None MG A 414 ( 3.1A)	1.18A	2bueA-4izgA: 0.4	2bueA-4izgA: 19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2J5M_A_ACTA1321_0 (CHLOROPEROXIDASE)	4izg	MANDELATE RACEMASE/MUCONATE LACTONIZING ENZYME, N-TERMINAL DOMAIN PROTEIN (Paracoccus denitrificans)	4 / 6	LEU A 161 ILE A 146 VAL A 180 ALA A 150	None	0.80A	2j5mA-4izgA: undetectable	2j5mA-4izgA: 22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VQY_A_PARA1201_1 (AAC(6')-IB)	4izg	MANDELATE RACEMASE/MUCONATE LACTONIZING ENZYME, N-TERMINAL DOMAIN PROTEIN (Paracoccus denitrificans)	5 / 12	TYR A 326 VAL A 52 TYR A 56 SER A 24 ASP A 194	None 4OP A 416 ( 4.7A) 4OP A 416 (-4.4A) None MG A 414 ( 2.6A)	1.47A	2vqyA-4izgA: undetectable	2vqyA-4izgA: 19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VQY_A_PARA1201_1 (AAC(6')-IB)	4izg	MANDELATE RACEMASE/MUCONATE LACTONIZING ENZYME, N-TERMINAL DOMAIN PROTEIN (Paracoccus denitrificans)	5 / 12	TYR A 326 VAL A 52 TYR A 56 SER A 24 ASP A 242	None 4OP A 416 ( 4.7A) 4OP A 416 (-4.4A) None MG A 414 ( 3.1A)	1.29A	2vqyA-4izgA: undetectable	2vqyA-4izgA: 19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZZM_A_SAMA401_0 (UNCHARACTERIZED PROTEIN MJ0883)	4izg	MANDELATE RACEMASE/MUCONATE LACTONIZING ENZYME, N-TERMINAL DOMAIN PROTEIN (Paracoccus denitrificans)	5 / 12	GLY A 166 ILE A 174 VAL A 177 LEU A 218 PHE A 216	None	1.11A	2zzmA-4izgA: undetectable	2zzmA-4izgA: 21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AY0_A_ADNA401_1 (UNCHARACTERIZED PROTEIN MJ0883)	4izg	MANDELATE RACEMASE/MUCONATE LACTONIZING ENZYME, N-TERMINAL DOMAIN PROTEIN (Paracoccus denitrificans)	5 / 10	ASP A 173 ILE A 174 VAL A 177 LEU A 218 PHE A 216	None	1.28A	3ay0A-4izgA: undetectable	3ay0A-4izgA: 21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AY0_B_ADNB402_1 (UNCHARACTERIZED PROTEIN MJ0883)	4izg	MANDELATE RACEMASE/MUCONATE LACTONIZING ENZYME, N-TERMINAL DOMAIN PROTEIN (Paracoccus denitrificans)	5 / 10	ASP A 173 ILE A 174 VAL A 177 LEU A 218 PHE A 216	None	1.26A	3ay0B-4izgA: undetectable	3ay0B-4izgA: 21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AY0_B_ADNB402_1 (UNCHARACTERIZED PROTEIN MJ0883)	4izg	MANDELATE RACEMASE/MUCONATE LACTONIZING ENZYME, N-TERMINAL DOMAIN PROTEIN (Paracoccus denitrificans)	5 / 10	GLY A 166 ASP A 173 ILE A 174 VAL A 177 PHE A 216	None	0.96A	3ay0B-4izgA: undetectable	3ay0B-4izgA: 21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HS6_B_EPAB1_1 (PROSTAGLANDIN G/H SYNTHASE 2)	4izg	MANDELATE RACEMASE/MUCONATE LACTONIZING ENZYME, N-TERMINAL DOMAIN PROTEIN (Paracoccus denitrificans)	5 / 12	GLY A 309 ASN A 317 GLY A 342 SER A 134 GLY A 319	None	0.91A	3hs6B-4izgA: undetectable	3hs6B-4izgA: 21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KO0_I_TFPI201_1 (PROTEIN S100-A4)	4izg	MANDELATE RACEMASE/MUCONATE LACTONIZING ENZYME, N-TERMINAL DOMAIN PROTEIN (Paracoccus denitrificans)	5 / 9	GLY A 353 PRO A 347 GLY A 45 ILE A 301 CYH A 305	None	1.16A	3ko0H-4izgA: undetectable 3ko0I-4izgA: 0.0	3ko0H-4izgA: 11.51 3ko0I-4izgA: 11.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NDT_A_ROCA101_2 (PROTEASE)	4izg	MANDELATE RACEMASE/MUCONATE LACTONIZING ENZYME, N-TERMINAL DOMAIN PROTEIN (Paracoccus denitrificans)	3 / 3	ARG A 338 VAL A 320 THR A 306	None	0.81A	3ndtA-4izgA: undetectable	3ndtA-4izgA: 13.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OHT_A_1N1A2000_1 (P38A)	4izg	MANDELATE RACEMASE/MUCONATE LACTONIZING ENZYME, N-TERMINAL DOMAIN PROTEIN (Paracoccus denitrificans)	5 / 12	ILE A 163 VAL A 235 ILE A 231 ILE A 165 ALA A 192	None	1.14A	3ohtA-4izgA: undetectable 3ohtB-4izgA: undetectable	3ohtA-4izgA: 23.13 3ohtB-4izgA: 23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SEL_X_DXCX75_0 (CYTOCHROME C7)	4izg	MANDELATE RACEMASE/MUCONATE LACTONIZING ENZYME, N-TERMINAL DOMAIN PROTEIN (Paracoccus denitrificans)	4 / 8	ILE A 308 LEU A 267 LYS A 114 GLY A 47	None None IOD A 402 (-3.6A) None	1.02A	3selX-4izgA: undetectable	3selX-4izgA: 10.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3VLN_A_ASCA904_0 (GLUTATHIONE S-TRANSFERASE OMEGA-1)	4izg	MANDELATE RACEMASE/MUCONATE LACTONIZING ENZYME, N-TERMINAL DOMAIN PROTEIN (Paracoccus denitrificans)	4 / 6	PHE A 158 LEU A 161 PRO A 159 SER A 134	None	1.29A	3vlnA-4izgA: undetectable	3vlnA-4izgA: 20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C5L_A_UEGA300_1 (PHOSPHOMETHYLPYRIMID INE KINASE)	4izg	MANDELATE RACEMASE/MUCONATE LACTONIZING ENZYME, N-TERMINAL DOMAIN PROTEIN (Paracoccus denitrificans)	5 / 11	GLY A 264 GLY A 262 VAL A 251 CYH A 283 CYH A 260	None	1.20A	4c5lA-4izgA: 2.4	4c5lA-4izgA: 20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C5L_D_UEGD300_1 (PHOSPHOMETHYLPYRIMID INE KINASE)	4izg	MANDELATE RACEMASE/MUCONATE LACTONIZING ENZYME, N-TERMINAL DOMAIN PROTEIN (Paracoccus denitrificans)	5 / 10	GLY A 264 GLY A 262 VAL A 251 CYH A 283 CYH A 260	None	1.20A	4c5lD-4izgA: 2.4	4c5lD-4izgA: 20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C5N_D_UEGD300_1 (PHOSPHOMETHYLPYRIMID INE KINASE)	4izg	MANDELATE RACEMASE/MUCONATE LACTONIZING ENZYME, N-TERMINAL DOMAIN PROTEIN (Paracoccus denitrificans)	5 / 10	GLY A 264 GLY A 262 VAL A 251 CYH A 283 CYH A 260	None	1.34A	4c5nD-4izgA: 3.0	4c5nD-4izgA: 20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4EAT_A_BEZA1000_0 (BENZOATE-COENZYME A LIGASE)	4izg	MANDELATE RACEMASE/MUCONATE LACTONIZING ENZYME, N-TERMINAL DOMAIN PROTEIN (Paracoccus denitrificans)	4 / 7	ALA A 129 ALA A 121 ILE A 308 GLY A 309	None	0.51A	4eatA-4izgA: undetectable	4eatA-4izgA: 21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4N49_A_SAMA601_1 (CAP-SPECIFIC MRNA (NUCLEOSIDE-2'-O-)-M ETHYLTRANSFERASE 1)	4izg	MANDELATE RACEMASE/MUCONATE LACTONIZING ENZYME, N-TERMINAL DOMAIN PROTEIN (Paracoccus denitrificans)	4 / 4	ASN A 317 GLY A 309 ASP A 247 ASP A 293	None None None 4OP A 416 ( 4.8A)	1.02A	4n49A-4izgA: undetectable	4n49A-4izgA: 21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4RTB_A_SAMA501_1 (HYDG PROTEIN)	4izg	MANDELATE RACEMASE/MUCONATE LACTONIZING ENZYME, N-TERMINAL DOMAIN PROTEIN (Paracoccus denitrificans)	3 / 3	GLU A 243 ARG A 269 GLN A 162	MG A 414 ( 4.3A) None 4OP A 416 (-3.0A)	0.97A	4rtbA-4izgA: 7.1	4rtbA-4izgA: 23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U9U_A_ACTA1502_0 (NA(+)-TRANSLOCATING NADH-QUINONE REDUCTASE SUBUNIT F)	4izg	MANDELATE RACEMASE/MUCONATE LACTONIZING ENZYME, N-TERMINAL DOMAIN PROTEIN (Paracoccus denitrificans)	4 / 5	ARG A 286 GLY A 256 ALA A 255 GLY A 258	None	0.83A	4u9uA-4izgA: undetectable	4u9uA-4izgA: 21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U9U_B_ACTB1502_0 (NA(+)-TRANSLOCATING NADH-QUINONE REDUCTASE SUBUNIT F)	4izg	MANDELATE RACEMASE/MUCONATE LACTONIZING ENZYME, N-TERMINAL DOMAIN PROTEIN (Paracoccus denitrificans)	4 / 5	ARG A 286 GLY A 256 ALA A 255 GLY A 258	None	0.91A	4u9uB-4izgA: 2.4	4u9uB-4izgA: 21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LF7_B_6V8B304_0 (PROTEASOME SUBUNIT BETA TYPE-6 PROTEASOME SUBUNIT BETA TYPE-7)	4izg	MANDELATE RACEMASE/MUCONATE LACTONIZING ENZYME, N-TERMINAL DOMAIN PROTEIN (Paracoccus denitrificans)	5 / 12	TYR A 99 THR A 33 THR A 32 GLY A 47 ALA A 103	None	1.13A	5lf7V-4izgA: undetectable 5lf7b-4izgA: undetectable	5lf7V-4izgA: 21.94 5lf7b-4izgA: 21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LF7_N_6V8N305_0 (PROTEASOME SUBUNIT BETA TYPE-6 PROTEASOME SUBUNIT BETA TYPE-7)	4izg	MANDELATE RACEMASE/MUCONATE LACTONIZING ENZYME, N-TERMINAL DOMAIN PROTEIN (Paracoccus denitrificans)	5 / 12	TYR A 99 THR A 33 THR A 32 GLY A 47 ALA A 103	None	1.13A	5lf7H-4izgA: undetectable 5lf7N-4izgA: undetectable	5lf7H-4izgA: 21.94 5lf7N-4izgA: 21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LG3_B_Z80B401_1 (GAMMA-AMINOBUTYRIC-A CID RECEPTOR SUBUNIT BETA-1)	4izg	MANDELATE RACEMASE/MUCONATE LACTONIZING ENZYME, N-TERMINAL DOMAIN PROTEIN (Paracoccus denitrificans)	5 / 9	ILE A 339 VAL A 320 THR A 306 ASP A 345 ILE A 337	None	1.48A	5lg3B-4izgA: undetectable	5lg3B-4izgA: 22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LG3_C_Z80C401_1 (GAMMA-AMINOBUTYRIC-A CID RECEPTOR SUBUNIT BETA-1)	4izg	MANDELATE RACEMASE/MUCONATE LACTONIZING ENZYME, N-TERMINAL DOMAIN PROTEIN (Paracoccus denitrificans)	5 / 9	ILE A 339 VAL A 320 THR A 306 ASP A 345 ILE A 337	None	1.48A	5lg3C-4izgA: undetectable	5lg3C-4izgA: 22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LG3_D_Z80D401_1 (GAMMA-AMINOBUTYRIC-A CID RECEPTOR SUBUNIT BETA-1)	4izg	MANDELATE RACEMASE/MUCONATE LACTONIZING ENZYME, N-TERMINAL DOMAIN PROTEIN (Paracoccus denitrificans)	5 / 9	ILE A 339 VAL A 320 THR A 306 ASP A 345 ILE A 337	None	1.48A	5lg3D-4izgA: undetectable	5lg3D-4izgA: 22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MFX_A_ACTA701_0 (GENOME POLYPROTEIN)	4izg	MANDELATE RACEMASE/MUCONATE LACTONIZING ENZYME, N-TERMINAL DOMAIN PROTEIN (Paracoccus denitrificans)	4 / 5	ARG A 119 THR A 306 HIS A 307 ALA A 310	None	1.30A	5mfxA-4izgA: undetectable	5mfxA-4izgA: 22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5N0O_A_SAMA501_1 (PEPTIDE N-METHYLTRANSFERASE)	4izg	MANDELATE RACEMASE/MUCONATE LACTONIZING ENZYME, N-TERMINAL DOMAIN PROTEIN (Paracoccus denitrificans)	3 / 3	ALA A 64 GLN A 31 THR A 33	None IOD A 404 ( 4.4A) None	0.70A	5n0oA-4izgA: undetectable	5n0oA-4izgA: 23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5N8J_E_DVAE7_0 (GLY-DTY-GLY-DLE-DAL- DSG-DVA-DAS-DGL-DSN- DSN-GLY STREPTAVIDIN)	4izg	MANDELATE RACEMASE/MUCONATE LACTONIZING ENZYME, N-TERMINAL DOMAIN PROTEIN (Paracoccus denitrificans)	3 / 3	TYR A 9 SER A 359 TRP A 46	None None IOD A 401 (-4.8A)	0.88A	5n8jB-4izgA: undetectable	5n8jB-4izgA: 18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5N8J_O_DVAO7_0 (GLY-DTY-GLY-DLE-DAL- DSG-DVA-DAS-DGL-DSN- DSN-GLY STREPTAVIDIN)	4izg	MANDELATE RACEMASE/MUCONATE LACTONIZING ENZYME, N-TERMINAL DOMAIN PROTEIN (Paracoccus denitrificans)	3 / 3	TYR A 9 SER A 359 TRP A 46	None None IOD A 401 (-4.8A)	0.84A	5n8jA-4izgA: undetectable	5n8jA-4izgA: 18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5N8J_P_DVAP5_0 (GLY-DTY-GLY-DLE-DAL- DSG-DVA-DAS-DGL-DSN- DSN-GLY STREPTAVIDIN)	4izg	MANDELATE RACEMASE/MUCONATE LACTONIZING ENZYME, N-TERMINAL DOMAIN PROTEIN (Paracoccus denitrificans)	3 / 3	TYR A 9 SER A 359 TRP A 46	None None IOD A 401 (-4.8A)	0.83A	5n8jD-4izgA: undetectable	5n8jD-4izgA: 18.94

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1E7B_A_HLTA4002_1","SERUM ALBUMIN","4izg","MANDELATE RACEMASE\/MUCONATE LACTONIZING ENZYME, N-TERMINAL DOMAIN PROTEIN","Paracoccus denitrificans",4,"ARG A 119;ALA A 121;ALA A 128;GLU A 130","None","1.05A","1e7bA-4izgA:undetectable","1e7bA-4izgA:20.61"],["1JIP_A_KTNA801_1","CYTOCHROME P450 107A1","4izg","MANDELATE RACEMASE\/MUCONATE LACTONIZING ENZYME, N-TERMINAL DOMAIN PROTEIN","Paracoccus denitrificans",5,"PHE A 279;ALA A 277;LEU A 123;ALA A 108;LEU A 124","None","1.35A","1jipA-4izgA:undetectable","1jipA-4izgA:23.05"],["1KQE_A_DVAA6_0","MINI-GRAMICIDIN A","4izg","MANDELATE RACEMASE\/MUCONATE LACTONIZING ENZYME, N-TERMINAL DOMAIN PROTEIN","Paracoccus denitrificans",3,"ALA A 328;VAL A  15;TRP A 296","None","0.86A","1kqeA-4izgA:undetectable;1kqeE-4izgA:undetectable","1kqeA-4izgA:5.59;1kqeE-4izgA:5.59"],["1KQE_B_DVAB6_0","MINI-GRAMICIDIN A","4izg","MANDELATE RACEMASE\/MUCONATE LACTONIZING ENZYME, N-TERMINAL DOMAIN PROTEIN","Paracoccus denitrificans",3,"ALA A 328;VAL A  15;TRP A 296","None","0.85A","1kqeB-4izgA:undetectable;1kqeD-4izgA:undetectable","1kqeB-4izgA:5.59;1kqeD-4izgA:5.59"],["1KQE_D_DVAD6_0","MINI-GRAMICIDIN A","4izg","MANDELATE RACEMASE\/MUCONATE LACTONIZING ENZYME, N-TERMINAL DOMAIN PROTEIN","Paracoccus denitrificans",3,"TRP A 296;ALA A 328;VAL A  15","None","0.87A","1kqeB-4izgA:undetectable;1kqeD-4izgA:undetectable","1kqeB-4izgA:5.59;1kqeD-4izgA:5.59"],["1KQE_E_DVAE6_0","MINI-GRAMICIDIN A","4izg","MANDELATE RACEMASE\/MUCONATE LACTONIZING ENZYME, N-TERMINAL DOMAIN PROTEIN","Paracoccus denitrificans",3,"TRP A 296;ALA A 328;VAL A  15","None","0.86A","1kqeA-4izgA:undetectable;1kqeE-4izgA:undetectable","1kqeA-4izgA:5.59;1kqeE-4izgA:5.59"],["1SGU_B_MK1B2632_2","POL POLYPROTEIN","4izg","MANDELATE RACEMASE\/MUCONATE LACTONIZING ENZYME, N-TERMINAL DOMAIN PROTEIN","Paracoccus denitrificans",5,"GLY A 271;ALA A 102;ASP A 105;ILE A 301;ALA A 295","None;None;None;None;4OP A 416 (-4.0A)","1.02A","1sguB-4izgA:undetectable","1sguB-4izgA:13.84"],["2BUE_A_RIOA1201_0","AAC(6')-IB","4izg","MANDELATE RACEMASE\/MUCONATE LACTONIZING ENZYME, N-TERMINAL DOMAIN PROTEIN","Paracoccus denitrificans",5,"TRP A 321;TYR A 326;TYR A  56;SER A  24;ASP A 242","4OP A 416 ( 3.8A);None;4OP A 416 (-4.4A);None; MG A 414 ( 3.1A)","1.18A","2bueA-4izgA:0.4","2bueA-4izgA:19.39"],["2J5M_A_ACTA1321_0","CHLOROPEROXIDASE","4izg","MANDELATE RACEMASE\/MUCONATE LACTONIZING ENZYME, N-TERMINAL DOMAIN PROTEIN","Paracoccus denitrificans",4,"LEU A 161;ILE A 146;VAL A 180;ALA A 150","None","0.80A","2j5mA-4izgA:undetectable","2j5mA-4izgA:22.06"],["2VQY_A_PARA1201_1","AAC(6')-IB","4izg","MANDELATE RACEMASE\/MUCONATE LACTONIZING ENZYME, N-TERMINAL DOMAIN PROTEIN","Paracoccus denitrificans",5,"TYR A 326;VAL A  52;TYR A  56;SER A  24;ASP A 194","None;4OP A 416 ( 4.7A);4OP A 416 (-4.4A);None; MG A 414 ( 2.6A)","1.47A","2vqyA-4izgA:undetectable","2vqyA-4izgA:19.39"],["2VQY_A_PARA1201_1","AAC(6')-IB","4izg","MANDELATE RACEMASE\/MUCONATE LACTONIZING ENZYME, N-TERMINAL DOMAIN PROTEIN","Paracoccus denitrificans",5,"TYR A 326;VAL A  52;TYR A  56;SER A  24;ASP A 242","None;4OP A 416 ( 4.7A);4OP A 416 (-4.4A);None; MG A 414 ( 3.1A)","1.29A","2vqyA-4izgA:undetectable","2vqyA-4izgA:19.39"],["2ZZM_A_SAMA401_0","UNCHARACTERIZED PROTEIN MJ0883","4izg","MANDELATE RACEMASE\/MUCONATE LACTONIZING ENZYME, N-TERMINAL DOMAIN PROTEIN","Paracoccus denitrificans",5,"GLY A 166;ILE A 174;VAL A 177;LEU A 218;PHE A 216","None","1.11A","2zzmA-4izgA:undetectable","2zzmA-4izgA:21.59"],["3AY0_A_ADNA401_1","UNCHARACTERIZED PROTEIN MJ0883","4izg","MANDELATE RACEMASE\/MUCONATE LACTONIZING ENZYME, N-TERMINAL DOMAIN PROTEIN","Paracoccus denitrificans",5,"ASP A 173;ILE A 174;VAL A 177;LEU A 218;PHE A 216","None","1.28A","3ay0A-4izgA:undetectable","3ay0A-4izgA:21.59"],["3AY0_B_ADNB402_1","UNCHARACTERIZED PROTEIN MJ0883","4izg","MANDELATE RACEMASE\/MUCONATE LACTONIZING ENZYME, N-TERMINAL DOMAIN PROTEIN","Paracoccus denitrificans",5,"ASP A 173;ILE A 174;VAL A 177;LEU A 218;PHE A 216","None","1.26A","3ay0B-4izgA:undetectable","3ay0B-4izgA:21.59"],["3AY0_B_ADNB402_1","UNCHARACTERIZED PROTEIN MJ0883","4izg","MANDELATE RACEMASE\/MUCONATE LACTONIZING ENZYME, N-TERMINAL DOMAIN PROTEIN","Paracoccus denitrificans",5,"GLY A 166;ASP A 173;ILE A 174;VAL A 177;PHE A 216","None","0.96A","3ay0B-4izgA:undetectable","3ay0B-4izgA:21.59"],["3HS6_B_EPAB1_1","PROSTAGLANDIN G\/H SYNTHASE 2","4izg","MANDELATE RACEMASE\/MUCONATE LACTONIZING ENZYME, N-TERMINAL DOMAIN PROTEIN","Paracoccus denitrificans",5,"GLY A 309;ASN A 317;GLY A 342;SER A 134;GLY A 319","None","0.91A","3hs6B-4izgA:undetectable","3hs6B-4izgA:21.25"],["3KO0_I_TFPI201_1","PROTEIN S100-A4;PROTEIN S100-A4","4izg","MANDELATE RACEMASE\/MUCONATE LACTONIZING ENZYME, N-TERMINAL DOMAIN PROTEIN","Paracoccus denitrificans",5,"GLY A 353;PRO A 347;GLY A  45;ILE A 301;CYH A 305","None","1.16A","3ko0H-4izgA:undetectable;3ko0I-4izgA:0.0","3ko0H-4izgA:11.51;3ko0I-4izgA:11.51"],["3NDT_A_ROCA101_2","PROTEASE","4izg","MANDELATE RACEMASE\/MUCONATE LACTONIZING ENZYME, N-TERMINAL DOMAIN PROTEIN","Paracoccus denitrificans",3,"ARG A 338;VAL A 320;THR A 306","None","0.81A","3ndtA-4izgA:undetectable","3ndtA-4izgA:13.32"],["3OHT_A_1N1A2000_1","P38A;P38A","4izg","MANDELATE RACEMASE\/MUCONATE LACTONIZING ENZYME, N-TERMINAL DOMAIN PROTEIN","Paracoccus denitrificans",5,"ILE A 163;VAL A 235;ILE A 231;ILE A 165;ALA A 192","None","1.14A","3ohtA-4izgA:undetectable;3ohtB-4izgA:undetectable","3ohtA-4izgA:23.13;3ohtB-4izgA:23.13"],["3SEL_X_DXCX75_0","CYTOCHROME C7","4izg","MANDELATE RACEMASE\/MUCONATE LACTONIZING ENZYME, N-TERMINAL DOMAIN PROTEIN","Paracoccus denitrificans",4,"ILE A 308;LEU A 267;LYS A 114;GLY A  47","None;None;IOD A 402 (-3.6A);None","1.02A","3selX-4izgA:undetectable","3selX-4izgA:10.71"],["3VLN_A_ASCA904_0","GLUTATHIONE S-TRANSFERASE OMEGA-1","4izg","MANDELATE RACEMASE\/MUCONATE LACTONIZING ENZYME, N-TERMINAL DOMAIN PROTEIN","Paracoccus denitrificans",4,"PHE A 158;LEU A 161;PRO A 159;SER A 134","None","1.29A","3vlnA-4izgA:undetectable","3vlnA-4izgA:20.79"],["4C5L_A_UEGA300_1","PHOSPHOMETHYLPYRIMIDINE KINASE","4izg","MANDELATE RACEMASE\/MUCONATE LACTONIZING ENZYME, N-TERMINAL DOMAIN PROTEIN","Paracoccus denitrificans",5,"GLY A 264;GLY A 262;VAL A 251;CYH A 283;CYH A 260","None","1.20A","4c5lA-4izgA:2.4","4c5lA-4izgA:20.72"],["4C5L_D_UEGD300_1","PHOSPHOMETHYLPYRIMIDINE KINASE","4izg","MANDELATE RACEMASE\/MUCONATE LACTONIZING ENZYME, N-TERMINAL DOMAIN PROTEIN","Paracoccus denitrificans",5,"GLY A 264;GLY A 262;VAL A 251;CYH A 283;CYH A 260","None","1.20A","4c5lD-4izgA:2.4","4c5lD-4izgA:20.72"],["4C5N_D_UEGD300_1","PHOSPHOMETHYLPYRIMIDINE KINASE","4izg","MANDELATE RACEMASE\/MUCONATE LACTONIZING ENZYME, N-TERMINAL DOMAIN PROTEIN","Paracoccus denitrificans",5,"GLY A 264;GLY A 262;VAL A 251;CYH A 283;CYH A 260","None","1.34A","4c5nD-4izgA:3.0","4c5nD-4izgA:20.72"],["4EAT_A_BEZA1000_0","BENZOATE-COENZYME A LIGASE","4izg","MANDELATE RACEMASE\/MUCONATE LACTONIZING ENZYME, N-TERMINAL DOMAIN PROTEIN","Paracoccus denitrificans",4,"ALA A 129;ALA A 121;ILE A 308;GLY A 309","None","0.51A","4eatA-4izgA:undetectable","4eatA-4izgA:21.96"],["4N49_A_SAMA601_1","CAP-SPECIFIC MRNA (NUCLEOSIDE-2'-O-)-METHYLTRANSFERASE 1","4izg","MANDELATE RACEMASE\/MUCONATE LACTONIZING ENZYME, N-TERMINAL DOMAIN PROTEIN","Paracoccus denitrificans",4,"ASN A 317;GLY A 309;ASP A 247;ASP A 293","None;None;None;4OP A 416 ( 4.8A)","1.02A","4n49A-4izgA:undetectable","4n49A-4izgA:21.12"],["4RTB_A_SAMA501_1","HYDG PROTEIN","4izg","MANDELATE RACEMASE\/MUCONATE LACTONIZING ENZYME, N-TERMINAL DOMAIN PROTEIN","Paracoccus denitrificans",3,"GLU A 243;ARG A 269;GLN A 162"," MG A 414 ( 4.3A);None;4OP A 416 (-3.0A)","0.97A","4rtbA-4izgA:7.1","4rtbA-4izgA:23.81"],["4U9U_A_ACTA1502_0","NA(+)-TRANSLOCATING NADH-QUINONE REDUCTASE SUBUNIT F","4izg","MANDELATE RACEMASE\/MUCONATE LACTONIZING ENZYME, N-TERMINAL DOMAIN PROTEIN","Paracoccus denitrificans",4,"ARG A 286;GLY A 256;ALA A 255;GLY A 258","None","0.83A","4u9uA-4izgA:undetectable","4u9uA-4izgA:21.63"],["4U9U_B_ACTB1502_0","NA(+)-TRANSLOCATING NADH-QUINONE REDUCTASE SUBUNIT F","4izg","MANDELATE RACEMASE\/MUCONATE LACTONIZING ENZYME, N-TERMINAL DOMAIN PROTEIN","Paracoccus denitrificans",4,"ARG A 286;GLY A 256;ALA A 255;GLY A 258","None","0.91A","4u9uB-4izgA:2.4","4u9uB-4izgA:21.63"],["5LF7_B_6V8B304_0","PROTEASOME SUBUNIT BETA TYPE-6;PROTEASOME SUBUNIT BETA TYPE-7","4izg","MANDELATE RACEMASE\/MUCONATE LACTONIZING ENZYME, N-TERMINAL DOMAIN PROTEIN","Paracoccus denitrificans",5,"TYR A  99;THR A  33;THR A  32;GLY A  47;ALA A 103","None","1.13A","5lf7V-4izgA:undetectable;5lf7b-4izgA:undetectable","5lf7V-4izgA:21.94;5lf7b-4izgA:21.08"],["5LF7_N_6V8N305_0","PROTEASOME SUBUNIT BETA TYPE-6;PROTEASOME SUBUNIT BETA TYPE-7","4izg","MANDELATE RACEMASE\/MUCONATE LACTONIZING ENZYME, N-TERMINAL DOMAIN PROTEIN","Paracoccus denitrificans",5,"TYR A  99;THR A  33;THR A  32;GLY A  47;ALA A 103","None","1.13A","5lf7H-4izgA:undetectable;5lf7N-4izgA:undetectable","5lf7H-4izgA:21.94;5lf7N-4izgA:21.08"],["5LG3_B_Z80B401_1","GAMMA-AMINOBUTYRIC-ACID RECEPTOR SUBUNIT BETA-1","4izg","MANDELATE RACEMASE\/MUCONATE LACTONIZING ENZYME, N-TERMINAL DOMAIN PROTEIN","Paracoccus denitrificans",5,"ILE A 339;VAL A 320;THR A 306;ASP A 345;ILE A 337","None","1.48A","5lg3B-4izgA:undetectable","5lg3B-4izgA:22.52"],["5LG3_C_Z80C401_1","GAMMA-AMINOBUTYRIC-ACID RECEPTOR SUBUNIT BETA-1","4izg","MANDELATE RACEMASE\/MUCONATE LACTONIZING ENZYME, N-TERMINAL DOMAIN PROTEIN","Paracoccus denitrificans",5,"ILE A 339;VAL A 320;THR A 306;ASP A 345;ILE A 337","None","1.48A","5lg3C-4izgA:undetectable","5lg3C-4izgA:22.52"],["5LG3_D_Z80D401_1","GAMMA-AMINOBUTYRIC-ACID RECEPTOR SUBUNIT BETA-1","4izg","MANDELATE RACEMASE\/MUCONATE LACTONIZING ENZYME, N-TERMINAL DOMAIN PROTEIN","Paracoccus denitrificans",5,"ILE A 339;VAL A 320;THR A 306;ASP A 345;ILE A 337","None","1.48A","5lg3D-4izgA:undetectable","5lg3D-4izgA:22.52"],["5MFX_A_ACTA701_0","GENOME POLYPROTEIN","4izg","MANDELATE RACEMASE\/MUCONATE LACTONIZING ENZYME, N-TERMINAL DOMAIN PROTEIN","Paracoccus denitrificans",4,"ARG A 119;THR A 306;HIS A 307;ALA A 310","None","1.30A","5mfxA-4izgA:undetectable","5mfxA-4izgA:22.17"],["5N0O_A_SAMA501_1","PEPTIDE N-METHYLTRANSFERASE","4izg","MANDELATE RACEMASE\/MUCONATE LACTONIZING ENZYME, N-TERMINAL DOMAIN PROTEIN","Paracoccus denitrificans",3,"ALA A  64;GLN A  31;THR A  33","None;IOD A 404 ( 4.4A);None","0.70A","5n0oA-4izgA:undetectable","5n0oA-4izgA:23.36"],["5N8J_E_DVAE7_0","GLY-DTY-GLY-DLE-DAL-DSG-DVA-DAS-DGL-DSN-DSN-GLY;STREPTAVIDIN","4izg","MANDELATE RACEMASE\/MUCONATE LACTONIZING ENZYME, N-TERMINAL DOMAIN PROTEIN","Paracoccus denitrificans",3,"TYR A   9;SER A 359;TRP A  46","None;None;IOD A 401 (-4.8A)","0.88A","5n8jB-4izgA:undetectable","5n8jB-4izgA:18.94"],["5N8J_O_DVAO7_0","GLY-DTY-GLY-DLE-DAL-DSG-DVA-DAS-DGL-DSN-DSN-GLY;STREPTAVIDIN","4izg","MANDELATE RACEMASE\/MUCONATE LACTONIZING ENZYME, N-TERMINAL DOMAIN PROTEIN","Paracoccus denitrificans",3,"TYR A   9;SER A 359;TRP A  46","None;None;IOD A 401 (-4.8A)","0.84A","5n8jA-4izgA:undetectable","5n8jA-4izgA:18.94"],["5N8J_P_DVAP5_0","GLY-DTY-GLY-DLE-DAL-DSG-DVA-DAS-DGL-DSN-DSN-GLY;STREPTAVIDIN","4izg","MANDELATE RACEMASE\/MUCONATE LACTONIZING ENZYME, N-TERMINAL DOMAIN PROTEIN","Paracoccus denitrificans",3,"TYR A   9;SER A 359;TRP A  46","None;None;IOD A 401 (-4.8A)","0.83A","5n8jD-4izgA:undetectable","5n8jD-4izgA:18.94"]]