SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4izx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DF7_A_MTXA501_2
(DIHYDROFOLATE
REDUCTASE)		 4izx RICIN B-LIKE LECTIN
(Macrolepiota
procera) 		3 / 3 TRP A 128
ARG A  89
THR A 127
 None
BAM  A 202 (-3.9A)
None
 0.99A 1df7A-4izxA:
undetectable		 1df7A-4izxA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HO5_A_ADNA1604_1
(5'-NUCLEOTIDASE)		 4izx RICIN B-LIKE LECTIN
(Macrolepiota
procera) 		5 / 11 ILE A  31
ASN A  28
GLY A 119
GLY A  33
ASP A  22
 None
None
None
None
LAT  A 201 (-2.8A)
 1.23A 1ho5A-4izxA:
undetectable		 1ho5A-4izxA:
13.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_A_ZMRA1478_1
(NEURAMINIDASE)		 4izx RICIN B-LIKE LECTIN
(Macrolepiota
procera) 		4 / 7 SER A  60
SER A  62
SER A  57
TRP A  44
 None
 0.92A 2cmlA-4izxA:
undetectable		 2cmlA-4izxA:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_B_ZMRB2478_1
(NEURAMINIDASE)		 4izx RICIN B-LIKE LECTIN
(Macrolepiota
procera) 		4 / 8 SER A  60
SER A  62
SER A  57
TRP A  44
 None
 0.88A 2cmlB-4izxA:
undetectable		 2cmlB-4izxA:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_C_ZMRC3478_1
(NEURAMINIDASE)		 4izx RICIN B-LIKE LECTIN
(Macrolepiota
procera) 		4 / 8 SER A  60
SER A  62
SER A  57
GLN A  42
 None
None
None
LAT  A 201 ( 4.4A)
 0.82A 2cmlC-4izxA:
undetectable		 2cmlC-4izxA:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_C_ZMRC3478_1
(NEURAMINIDASE)		 4izx RICIN B-LIKE LECTIN
(Macrolepiota
procera) 		4 / 8 SER A  60
SER A  62
SER A  57
TRP A  44
 None
 0.94A 2cmlC-4izxA:
undetectable		 2cmlC-4izxA:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_D_ZMRD4478_1
(NEURAMINIDASE)		 4izx RICIN B-LIKE LECTIN
(Macrolepiota
procera) 		4 / 8 SER A  60
SER A  62
SER A  57
TRP A  44
 None
 1.03A 2cmlD-4izxA:
undetectable		 2cmlD-4izxA:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_E_ACHE1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 4izx RICIN B-LIKE LECTIN
(Macrolepiota
procera) 		4 / 7 GLN A   3
ILE A  87
TRP A  53
TYR A  10
 BAM  A 202 (-2.9A)
BAM  A 202 (-4.2A)
BAM  A 202 ( 4.3A)
None
 1.36A 2xz5D-4izxA:
undetectable
2xz5E-4izxA:
undetectable		 2xz5D-4izxA:
19.91
2xz5E-4izxA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB501_1
(HEMOLYTIC LECTIN
CEL-III)		 4izx RICIN B-LIKE LECTIN
(Macrolepiota
procera) 		4 / 5 ASP A 109
SER A 111
GLY A 112
TRP A 125
 None
 0.68A 3w9tB-4izxA:
16.5		 3w9tB-4izxA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1003_1
(HEMOLYTIC LECTIN
CEL-III)		 4izx RICIN B-LIKE LECTIN
(Macrolepiota
procera) 		4 / 5 ASP A 109
SER A 111
GLY A 112
TRP A 125
 None
 0.68A 3w9tC-4izxA:
16.4		 3w9tC-4izxA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1005_1
(HEMOLYTIC LECTIN
CEL-III)		 4izx RICIN B-LIKE LECTIN
(Macrolepiota
procera) 		3 / 3 ASP A  22
GLY A  25
TYR A  34
 LAT  A 201 (-2.8A)
LAT  A 201 (-3.5A)
LAT  A 201 ( 3.5A)
 0.54A 3w9tC-4izxA:
16.4		 3w9tC-4izxA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD501_1
(HEMOLYTIC LECTIN
CEL-III)		 4izx RICIN B-LIKE LECTIN
(Macrolepiota
procera) 		4 / 5 ASP A 109
SER A 111
GLY A 112
TRP A 125
 None
 0.68A 3w9tD-4izxA:
15.3		 3w9tD-4izxA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF501_1
(HEMOLYTIC LECTIN
CEL-III)		 4izx RICIN B-LIKE LECTIN
(Macrolepiota
procera) 		4 / 4 ASP A 109
SER A 111
GLY A 112
TRP A 125
 None
 0.66A 3w9tF-4izxA:
16.3		 3w9tF-4izxA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG503_1
(HEMOLYTIC LECTIN
CEL-III)		 4izx RICIN B-LIKE LECTIN
(Macrolepiota
procera) 		3 / 3 ASP A  22
GLY A  25
TYR A  34
 LAT  A 201 (-2.8A)
LAT  A 201 (-3.5A)
LAT  A 201 ( 3.5A)
 0.53A 3w9tG-4izxA:
16.5		 3w9tG-4izxA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4izx RICIN B-LIKE LECTIN
(Macrolepiota
procera) 		4 / 6 ILE A  31
LEU A  76
ARG A  56
THR A  54
 None
 1.19A 3wg7A-4izxA:
undetectable
3wg7J-4izxA:
undetectable		 3wg7A-4izxA:
12.92
3wg7J-4izxA:
16.43