SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4j0m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA350_2
(PROTEIN (ADENOSINE
KINASE))
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana)
3 / 3 LEU A 573
SER A 569
ASN A 545
None
0.84A 1bx4A-4j0mA:
undetectable
1bx4A-4j0mA:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IHI_A_IU5A326_1
(3-ALPHA-HYDROXYSTERO
ID DEHYDROGENASE)
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana)
5 / 10 VAL A 146
TYR A 145
VAL A 156
ILE A 158
LEU A  93
None
1.48A 1ihiA-4j0mA:
undetectable
1ihiA-4j0mA:
16.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JR1_B_MOAB1333_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE 2)
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana)
4 / 8 SER A 136
ASN A 161
GLY A 111
GLY A  91
None
0.80A 1jr1B-4j0mA:
undetectable
1jr1B-4j0mA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T03_P_TFOP822_1
(POL POLYPROTEIN
SYNTHETIC
OLIGONUCLEOTIDE
PRIMER)
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana)
4 / 7 ASP A 717
ASP A 715
ASP A 693
HIS A 696
None
1.34A 1t03A-4j0mA:
undetectable
1t03A-4j0mA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana)
4 / 7 LEU A 228
PHE A 230
LEU A 203
PHE A 199
None
1.01A 1v55C-4j0mA:
undetectable
1v55J-4j0mA:
undetectable
1v55C-4j0mA:
16.01
1v55J-4j0mA:
5.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_A_ZMRA1478_1
(NEURAMINIDASE)
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana)
4 / 7 SER A 159
SER A 134
SER A 133
ASN A 157
NAG  A 811 (-3.5A)
NAG  A 811 (-3.2A)
NAG  A 811 (-3.4A)
NAG  A 811 (-1.8A)
1.14A 2cmlA-4j0mA:
undetectable
2cmlA-4j0mA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_B_ZMRB2478_1
(NEURAMINIDASE)
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana)
5 / 8 ASP A 207
SER A 183
SER A 159
ASN A 157
GLN A 110
None
None
NAG  A 811 (-3.5A)
NAG  A 811 (-1.8A)
None
1.29A 2cmlB-4j0mA:
undetectable
2cmlB-4j0mA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_C_ZMRC3478_1
(NEURAMINIDASE)
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana)
5 / 8 ASP A 207
SER A 183
SER A 159
ASN A 157
GLN A 110
None
None
NAG  A 811 (-3.5A)
NAG  A 811 (-1.8A)
None
1.34A 2cmlC-4j0mA:
undetectable
2cmlC-4j0mA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_C_ZMRC3478_1
(NEURAMINIDASE)
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana)
4 / 8 SER A 159
SER A 134
SER A 133
ASN A 157
NAG  A 811 (-3.5A)
NAG  A 811 (-3.2A)
NAG  A 811 (-3.4A)
NAG  A 811 (-1.8A)
1.11A 2cmlC-4j0mA:
undetectable
2cmlC-4j0mA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_D_ZMRD4478_1
(NEURAMINIDASE)
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana)
4 / 8 SER A 159
SER A 134
SER A 133
ASN A 157
NAG  A 811 (-3.5A)
NAG  A 811 (-3.2A)
NAG  A 811 (-3.4A)
NAG  A 811 (-1.8A)
1.12A 2cmlD-4j0mA:
undetectable
2cmlD-4j0mA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_D_ZMRD4478_1
(NEURAMINIDASE)
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana)
4 / 8 SER A 183
SER A 159
ASN A 157
GLN A 110
None
NAG  A 811 (-3.5A)
NAG  A 811 (-1.8A)
None
1.11A 2cmlD-4j0mA:
undetectable
2cmlD-4j0mA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_A_BEZA352_0
(D-AMINO-ACID OXIDASE)
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana)
4 / 6 LEU A 670
TYR A 659
ILE A 675
GLY A 565
None
0.92A 2du8A-4j0mA:
undetectable
2du8A-4j0mA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_P_CHDP310_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana)
4 / 7 LEU A 228
PHE A 230
LEU A 203
PHE A 199
None
1.01A 2dysP-4j0mA:
undetectable
2dysW-4j0mA:
undetectable
2dysP-4j0mA:
16.01
2dysW-4j0mA:
5.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana)
4 / 7 LEU A 228
PHE A 230
LEU A 203
PHE A 199
None
0.99A 2eijC-4j0mA:
undetectable
2eijJ-4j0mA:
undetectable
2eijC-4j0mA:
16.01
2eijJ-4j0mA:
5.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana)
4 / 7 LEU A 228
PHE A 230
LEU A 203
PHE A 199
None
1.02A 2eimC-4j0mA:
undetectable
2eimJ-4j0mA:
undetectable
2eimC-4j0mA:
16.01
2eimJ-4j0mA:
5.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana)
4 / 7 LEU A 228
PHE A 230
LEU A 203
PHE A 199
None
0.99A 2eimP-4j0mA:
undetectable
2eimW-4j0mA:
undetectable
2eimP-4j0mA:
16.01
2eimW-4j0mA:
5.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana)
4 / 7 LEU A 228
PHE A 230
LEU A 203
PHE A 199
None
1.00A 2einC-4j0mA:
undetectable
2einJ-4j0mA:
undetectable
2einC-4j0mA:
16.01
2einJ-4j0mA:
5.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GVC_B_MMZB501_1
(MONOOXYGENASE)
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana)
3 / 3 ASN A  51
TYR A 113
SER A  48
None
0.90A 2gvcB-4j0mA:
undetectable
2gvcB-4j0mA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GVC_E_MMZE501_1
(MONOOXYGENASE)
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana)
3 / 3 ASN A  51
TYR A 113
SER A  48
None
0.88A 2gvcE-4j0mA:
undetectable
2gvcE-4j0mA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2L8M_A_CAMA415_0
(CAMPHOR
5-MONOOXYGENASE)
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana)
5 / 9 TYR A 140
VAL A 146
VAL A 180
ILE A 158
VAL A 156
None
1.38A 2l8mA-4j0mA:
undetectable
2l8mA-4j0mA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V57_A_PRLA1188_0
(TETR FAMILY
TRANSCRIPTIONAL
REPRESSOR LFRR)
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana)
4 / 8 HIS A 696
SER A 695
ASN A 720
TYR A 648
None
1.10A 2v57A-4j0mA:
undetectable
2v57A-4j0mA:
12.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V57_C_PRLC1187_0
(TETR FAMILY
TRANSCRIPTIONAL
REPRESSOR LFRR)
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana)
4 / 8 HIS A 696
SER A 695
ASN A 720
TYR A 648
None
1.10A 2v57C-4j0mA:
undetectable
2v57C-4j0mA:
12.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_A_QPSA1060_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana)
5 / 12 SER A 197
SER A 221
THR A 246
ASN A 249
GLY A 226
None
None
None
None
NAG  A 813 ( 3.7A)
1.13A 2x2iA-4j0mA:
undetectable
2x2iA-4j0mA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_C_QPSC1060_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana)
5 / 12 SER A 197
SER A 221
THR A 246
ASN A 249
GLY A 226
None
None
None
None
NAG  A 813 ( 3.7A)
1.19A 2x2iC-4j0mA:
undetectable
2x2iC-4j0mA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y05_A_RALA802_1
(PROSTAGLANDIN
REDUCTASE 1)
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana)
4 / 7 VAL A 738
TYR A 741
ASN A 744
GLY A 746
None
0.88A 2y05A-4j0mA:
undetectable
2y05B-4j0mA:
undetectable
2y05A-4j0mA:
19.85
2y05B-4j0mA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_B_SAMB801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana)
4 / 8 ILE A 363
ASN A 344
SER A 370
SER A 366
None
1.10A 2zw9B-4j0mA:
undetectable
2zw9B-4j0mA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana)
4 / 6 LEU A 228
PHE A 230
LEU A 203
PHE A 199
None
1.00A 2zxwP-4j0mA:
undetectable
2zxwW-4j0mA:
undetectable
2zxwP-4j0mA:
16.01
2zxwW-4j0mA:
5.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZA_A_FOLA164_0
(DIHYDROFOLATE
REDUCTASE)
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana)
5 / 12 ILE A 466
LEU A 462
ILE A 446
LEU A 455
THR A 488
None
1.20A 2zzaA-4j0mA:
undetectable
2zzaA-4j0mA:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZM_A_SAMA401_0
(UNCHARACTERIZED
PROTEIN MJ0883)
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana)
5 / 12 PHE A 114
GLY A 117
ASN A  94
VAL A  46
LEU A 109
None
1.05A 2zzmA-4j0mA:
undetectable
2zzmA-4j0mA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana)
4 / 6 LEU A 228
PHE A 230
LEU A 203
PHE A 199
None
1.01A 3abkP-4j0mA:
undetectable
3abkW-4j0mA:
undetectable
3abkP-4j0mA:
16.01
3abkW-4j0mA:
5.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana)
4 / 6 LEU A 228
PHE A 230
LEU A 203
PHE A 199
None
0.97A 3ag1C-4j0mA:
undetectable
3ag1J-4j0mA:
undetectable
3ag1C-4j0mA:
16.01
3ag1J-4j0mA:
5.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIA_A_SAMA206_0
(UPF0217 PROTEIN
MJ1640)
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana)
4 / 6 LEU A  93
GLY A  91
LEU A 132
SER A 133
None
None
None
NAG  A 811 (-3.4A)
0.90A 3aiaA-4j0mA:
undetectable
3aiaA-4j0mA:
14.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_P_CHDP1271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana)
4 / 7 LEU A 228
PHE A 230
LEU A 203
PHE A 199
None
0.98A 3asnP-4j0mA:
undetectable
3asnW-4j0mA:
undetectable
3asnP-4j0mA:
16.01
3asnW-4j0mA:
5.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_P_CHDP1271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana)
4 / 7 LEU A 228
PHE A 230
LEU A 203
PHE A 199
None
1.01A 3asoP-4j0mA:
undetectable
3asoW-4j0mA:
undetectable
3asoP-4j0mA:
16.01
3asoW-4j0mA:
5.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AY0_B_ADNB402_1
(UNCHARACTERIZED
PROTEIN MJ0883)
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana)
5 / 10 PHE A 114
GLY A 117
ASN A  94
VAL A  46
LEU A 109
None
1.09A 3ay0B-4j0mA:
undetectable
3ay0B-4j0mA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IXL_A_PACA5000_0
(ARYLMALONATE
DECARBOXYLASE)
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana)
5 / 10 THR A  92
SER A  45
VAL A  96
GLY A 117
GLY A 118
None
1.25A 3ixlA-4j0mA:
undetectable
3ixlA-4j0mA:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_A_AICA375_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana)
5 / 11 GLY A 690
LEU A 668
ASN A 669
LEU A 716
LEU A 686
BLD  A 804 ( 3.8A)
None
None
None
None
1.33A 3ndvA-4j0mA:
undetectable
3ndvB-4j0mA:
undetectable
3ndvA-4j0mA:
18.38
3ndvB-4j0mA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_B_AICB376_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana)
5 / 11 LEU A 686
GLY A 690
LEU A 668
ASN A 669
LEU A 716
None
BLD  A 804 ( 3.8A)
None
None
None
1.33A 3ndvA-4j0mA:
undetectable
3ndvB-4j0mA:
undetectable
3ndvA-4j0mA:
18.38
3ndvB-4j0mA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_C_AICC375_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana)
5 / 11 GLY A 690
LEU A 668
ASN A 669
LEU A 716
LEU A 686
BLD  A 804 ( 3.8A)
None
None
None
None
1.31A 3ndvC-4j0mA:
undetectable
3ndvD-4j0mA:
undetectable
3ndvC-4j0mA:
18.38
3ndvD-4j0mA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_D_AICD374_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana)
5 / 11 LEU A 686
GLY A 690
LEU A 668
ASN A 669
LEU A 716
None
BLD  A 804 ( 3.8A)
None
None
None
1.34A 3ndvC-4j0mA:
undetectable
3ndvD-4j0mA:
undetectable
3ndvC-4j0mA:
18.38
3ndvD-4j0mA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGP_A_017A200_2
(FIV PROTEASE)
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana)
5 / 10 LEU A 309
ILE A 363
VAL A 358
ILE A 350
LEU A 333
None
0.96A 3ogpB-4j0mA:
undetectable
3ogpB-4j0mA:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_B_DSFB319_1
(GLR4197 PROTEIN)
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana)
5 / 9 PRO A 564
ILE A 646
VAL A 651
ILE A 655
ILE A 675
None
1.02A 3p4wB-4j0mA:
undetectable
3p4wB-4j0mA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_D_DSFD319_1
(GLR4197 PROTEIN)
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana)
5 / 10 PRO A 564
ILE A 646
VAL A 651
ILE A 655
ILE A 675
None
1.03A 3p4wD-4j0mA:
undetectable
3p4wD-4j0mA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_E_DSFE319_1
(GLR4197 PROTEIN)
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana)
5 / 10 PRO A 564
ILE A 646
VAL A 651
ILE A 655
ILE A 675
None
1.03A 3p4wE-4j0mA:
undetectable
3p4wE-4j0mA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PMZ_E_TUBE220_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana)
4 / 6 GLN A 583
MET A 630
SER A 384
SER A 383
None
1.34A 3pmzD-4j0mA:
undetectable
3pmzD-4j0mA:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SG9_B_KANB305_1
(APH(2'')-ID)
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana)
4 / 8 ASN A 160
ASP A 207
SER A 232
ASP A 181
NAG  A 812 (-3.6A)
None
NAG  A 805 ( 4.8A)
NAG  A 811 (-3.9A)
1.01A 3sg9B-4j0mA:
undetectable
3sg9B-4j0mA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TEH_B_DAHB786_1
(PHENYLALANYL-TRNA
SYNTHETASE BETA
CHAIN)
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana)
4 / 7 PRO A 576
GLY A 639
ALA A 637
PHE A 635
None
0.93A 3tehB-4j0mA:
undetectable
3tehB-4j0mA:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_H_CLMH221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana)
5 / 12 THR A  92
SER A  45
PHE A  41
SER A 116
VAL A 146
None
1.08A 3u9fH-4j0mA:
undetectable
3u9fI-4j0mA:
undetectable
3u9fH-4j0mA:
12.64
3u9fI-4j0mA:
12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_O_CLMO221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana)
5 / 11 THR A  92
SER A  45
PHE A  41
SER A 116
VAL A 146
None
1.16A 3u9fM-4j0mA:
undetectable
3u9fO-4j0mA:
undetectable
3u9fM-4j0mA:
12.64
3u9fO-4j0mA:
12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana)
4 / 6 LEU A 228
PHE A 230
LEU A 203
PHE A 199
None
1.01A 3wg7C-4j0mA:
undetectable
3wg7J-4j0mA:
undetectable
3wg7C-4j0mA:
16.01
3wg7J-4j0mA:
5.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZS3_A_ACTA1224_0
(THAUMATIN-LIKE
PROTEIN)
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana)
4 / 5 SER A 234
THR A 209
TYR A 184
ASP A 181
NAG  A 805 (-2.7A)
NAG  A 805 ( 4.4A)
None
NAG  A 811 (-3.9A)
1.27A 3zs3A-4j0mA:
undetectable
3zs3A-4j0mA:
15.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JQ1_B_NPSB401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana)
5 / 8 VAL A 146
TYR A 145
VAL A 156
ILE A 158
LEU A  93
None
1.38A 4jq1B-4j0mA:
undetectable
4jq1B-4j0mA:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JTQ_A_FLPA401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana)
5 / 10 VAL A 146
TYR A 145
VAL A 156
ILE A 158
LEU A  93
None
1.47A 4jtqA-4j0mA:
undetectable
4jtqA-4j0mA:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JTQ_B_FLPB401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana)
5 / 9 VAL A 146
TYR A 145
VAL A 156
ILE A 158
LEU A  93
None
1.49A 4jtqB-4j0mA:
undetectable
4jtqB-4j0mA:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8F_A_BRLA501_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana)
4 / 5 GLY A 118
LEU A 127
LEU A 109
LEU A 182
None
0.85A 4o8fA-4j0mA:
undetectable
4o8fA-4j0mA:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PO0_A_NPSA603_1
(SERUM ALBUMIN)
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana)
5 / 10 LEU A 187
LEU A 167
VAL A 180
LEU A 203
LEU A 177
None
1.21A 4po0A-4j0mA:
undetectable
4po0A-4j0mA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0R_A_PX9A201_0
(BETA-LACTOGLOBULIN)
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana)
5 / 12 LEU A 455
ILE A 431
LEU A 428
ILE A 407
VAL A 418
None
0.70A 4y0rA-4j0mA:
undetectable
4y0rA-4j0mA:
11.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana)
4 / 7 LEU A 228
PHE A 230
LEU A 203
PHE A 199
None
0.95A 5b1bP-4j0mA:
undetectable
5b1bW-4j0mA:
undetectable
5b1bP-4j0mA:
16.01
5b1bW-4j0mA:
5.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_A_VDYA201_2
(CDL2.2)
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana)
5 / 12 LEU A 455
ILE A 431
LEU A 428
PRO A 402
LEU A 462
None
1.18A 5ienA-4j0mA:
undetectable
5ienA-4j0mA:
10.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana)
4 / 5 LEU A 228
PHE A 230
LEU A 203
PHE A 199
None
1.01A 5iy5P-4j0mA:
undetectable
5iy5W-4j0mA:
undetectable
5iy5P-4j0mA:
16.17
5iy5W-4j0mA:
5.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O4Y_A_CCSA14_0
(PHE-MAA-ASN-PRO-HIS-
LEU-SER-TRP-SER-TRP-
9KK-9KK-ARG-CCS-GLY-
NH2)
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana)
4 / 6 ASN A 744
LEU A 747
ARG A 753
GLY A 749
None
1.15A 5o4yA-4j0mA:
undetectable
5o4yA-4j0mA:
1.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana)
5 / 10 ILE A 515
ILE A 519
LEU A 525
ILE A 646
ASN A 555
None
1.39A 5vkqA-4j0mA:
undetectable
5vkqD-4j0mA:
undetectable
5vkqA-4j0mA:
16.87
5vkqD-4j0mA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1808_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana)
5 / 10 ILE A 646
ASN A 555
ILE A 515
ILE A 519
LEU A 525
None
1.39A 5vkqA-4j0mA:
undetectable
5vkqB-4j0mA:
undetectable
5vkqA-4j0mA:
16.87
5vkqB-4j0mA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana)
5 / 10 ILE A 646
ASN A 555
ILE A 515
ILE A 519
LEU A 525
None
1.38A 5vkqC-4j0mA:
undetectable
5vkqD-4j0mA:
undetectable
5vkqC-4j0mA:
16.87
5vkqD-4j0mA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W7B_B_PA1B204_1
(ACYLOXYACYL
HYDROLASE SMALL
SUBUNIT
ACYLOXYACYL
HYDROLASE LARGE
SUBUNIT)
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana)
3 / 3 GLY A 386
ASN A 412
ARG A 611
None
0.77A 5w7bD-4j0mA:
undetectable
5w7bD-4j0mA:
7.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana)
4 / 6 LEU A 228
PHE A 230
LEU A 203
PHE A 199
None
0.99A 5w97C-4j0mA:
undetectable
5w97J-4j0mA:
undetectable
5w97C-4j0mA:
16.01
5w97J-4j0mA:
5.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana)
4 / 5 LEU A 228
PHE A 230
LEU A 203
PHE A 199
None
0.95A 5x1fC-4j0mA:
undetectable
5x1fJ-4j0mA:
undetectable
5x1fC-4j0mA:
16.01
5x1fJ-4j0mA:
5.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_P_CHDP304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana)
4 / 7 LEU A 228
PHE A 230
LEU A 203
PHE A 199
None
0.97A 5x1fP-4j0mA:
undetectable
5x1fW-4j0mA:
undetectable
5x1fP-4j0mA:
16.01
5x1fW-4j0mA:
5.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_C_SAMC901_0
(MRNA CAPPING ENZYME
P5)
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana)
5 / 11 VAL A  53
SER A  48
SER A  87
LEU A  84
ASN A 112
None
1.19A 5x6yC-4j0mA:
2.8
5x6yC-4j0mA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana)
4 / 5 LEU A 228
PHE A 230
LEU A 203
PHE A 199
None
0.98A 5xdxC-4j0mA:
undetectable
5xdxJ-4j0mA:
undetectable
5xdxC-4j0mA:
16.15
5xdxJ-4j0mA:
5.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana)
4 / 5 LEU A 228
PHE A 230
LEU A 203
PHE A 199
None
1.02A 5xdxP-4j0mA:
undetectable
5xdxW-4j0mA:
undetectable
5xdxP-4j0mA:
16.15
5xdxW-4j0mA:
5.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana)
4 / 7 LEU A 228
PHE A 230
LEU A 203
PHE A 199
None
0.95A 5z85C-4j0mA:
undetectable
5z85J-4j0mA:
undetectable
5z85C-4j0mA:
16.01
5z85J-4j0mA:
5.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana)
4 / 7 LEU A 228
PHE A 230
LEU A 203
PHE A 199
None
0.93A 5zcoC-4j0mA:
undetectable
5zcoJ-4j0mA:
undetectable
5zcoC-4j0mA:
16.01
5zcoJ-4j0mA:
5.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana)
4 / 7 LEU A 228
PHE A 230
LEU A 203
PHE A 199
None
0.94A 5zcqC-4j0mA:
undetectable
5zcqJ-4j0mA:
undetectable
5zcqC-4j0mA:
16.01
5zcqJ-4j0mA:
5.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DLZ_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana)
5 / 10 LEU A 563
LEU A 554
ASP A 553
ILE A 675
SER A 647
None
1.30A 6dlzB-4j0mA:
undetectable
6dlzC-4j0mA:
undetectable
6dlzB-4j0mA:
7.66
6dlzC-4j0mA:
7.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DLZ_D_CYZD1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana)
5 / 11 ILE A 675
SER A 647
LEU A 563
LEU A 554
ASP A 553
None
1.30A 6dlzA-4j0mA:
undetectable
6dlzD-4j0mA:
undetectable
6dlzA-4j0mA:
7.66
6dlzD-4j0mA:
7.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM0_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana)
5 / 10 LEU A 563
LEU A 554
ASP A 553
ILE A 675
SER A 647
None
1.30A 6dm0B-4j0mA:
undetectable
6dm0C-4j0mA:
undetectable
6dm0B-4j0mA:
7.66
6dm0C-4j0mA:
7.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM1_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana)
5 / 10 LEU A 563
LEU A 554
ASP A 553
ILE A 675
SER A 647
None
1.29A 6dm1B-4j0mA:
undetectable
6dm1C-4j0mA:
undetectable
6dm1B-4j0mA:
7.66
6dm1C-4j0mA:
7.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM1_D_CYZD1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana)
5 / 11 ILE A 675
SER A 647
LEU A 563
LEU A 554
ASP A 553
None
1.29A 6dm1A-4j0mA:
undetectable
6dm1D-4j0mA:
undetectable
6dm1A-4j0mA:
7.66
6dm1D-4j0mA:
7.66