SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4j1g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1AX9_A_EDRA999_1 (ACETYLCHOLINESTERASE)	4j1g	NUCLEOCAPSID (Leanyer virus)	4 / 8	GLY A 149 PHE A 46 PHE A 45 HIS A 49	None None None U E 8 ( 4.0A)	0.99A	1ax9A-4j1gA: undetectable	1ax9A-4j1gA: 19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MCN_P_DHIP1_0 (IMMUNOGLOBULIN LAMBDA DIMER MCG (LIGHT CHAIN) PEPTIDE N-ACETYL-D-HIS-L-PRO -NH2)	4j1g	NUCLEOCAPSID (Leanyer virus)	3 / 3	PHE A 20 TYR A 101 PRO A 22	U E 1 ( 3.6A) None U E 1 ( 4.7A)	1.13A	1mcnA-4j1gA: undetectable 1mcnB-4j1gA: undetectable 1mcnP-4j1gA: undetectable	1mcnA-4j1gA: 21.95 1mcnB-4j1gA: 21.95 1mcnP-4j1gA: 3.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W98_B_P1ZB1356_1 (PROSTAGLANDIN REDUCTASE 2)	4j1g	NUCLEOCAPSID (Leanyer virus)	4 / 8	TYR A 33 ILE A 93 TYR A 26 LEU A 102	None	0.90A	2w98B-4j1gA: undetectable	2w98B-4j1gA: 19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EUM_B_ACTB603_0 (LIPID A EXPORT ATP-BINDING/PERMEASE PROTEIN MSBA)	4j1g	NUCLEOCAPSID (Leanyer virus)	4 / 4	ALA A 92 ASN A 91 ARG A 97 ILE A 93	None None U E 3 ( 4.0A) None	1.29A	5eumB-4j1gA: undetectable	5eumB-4j1gA: 24.13

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1AX9_A_EDRA999_1","ACETYLCHOLINESTERASE","4j1g","NUCLEOCAPSID","Leanyer virus",4,"GLY A 149;PHE A  46;PHE A  45;HIS A  49","None;None;None;  U E   8 ( 4.0A)","0.99A","1ax9A-4j1gA:undetectable","1ax9A-4j1gA:19.04"],["1MCN_P_DHIP1_0","IMMUNOGLOBULIN LAMBDA DIMER MCG (LIGHT CHAIN);PEPTIDE N-ACETYL-D-HIS-L-PRO-NH2","4j1g","NUCLEOCAPSID","Leanyer virus",3,"PHE A  20;TYR A 101;PRO A  22","  U E   1 ( 3.6A);None;  U E   1 ( 4.7A)","1.13A","1mcnA-4j1gA:undetectable;1mcnB-4j1gA:undetectable;1mcnP-4j1gA:undetectable","1mcnA-4j1gA:21.95;1mcnB-4j1gA:21.95;1mcnP-4j1gA:3.28"],["2W98_B_P1ZB1356_1","PROSTAGLANDIN REDUCTASE 2","4j1g","NUCLEOCAPSID","Leanyer virus",4,"TYR A  33;ILE A  93;TYR A  26;LEU A 102","None","0.90A","2w98B-4j1gA:undetectable","2w98B-4j1gA:19.44"],["5EUM_B_ACTB603_0","LIPID A EXPORT ATP-BINDING\/PERMEASE PROTEIN MSBA","4j1g","NUCLEOCAPSID","Leanyer virus",4,"ALA A  92;ASN A  91;ARG A  97;ILE A  93","None;None;  U E   3 ( 4.0A);None","1.29A","5eumB-4j1gA:undetectable","5eumB-4j1gA:24.13"]]