SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4j1v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_A_ACTA1117_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 4j1v MOB KINASE ACTIVATOR
1A
(Homo
sapiens) 		3 / 3 ASP A 197
ARG A 198
ARG A 199
 None
 0.95A 2j9dA-4j1vA:
undetectable
2j9dC-4j1vA:
undetectable		 2j9dA-4j1vA:
18.38
2j9dC-4j1vA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I90_A_ACTA500_0
(1-PHOSPHATIDYLINOSIT
OL PHOSPHODIESTERASE)		 4j1v MOB KINASE ACTIVATOR
1A
NS5A DOMAIN II
PEPTIDE
(Homo
sapiens;
Hepacivirus
C) 		3 / 3 LYS E 308
ARG A 154
TRP A 121
 None
 1.35A 4i90A-4j1vE:
undetectable		 4i90A-4j1vE:
4.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECT_A_SAMA1300_0
(STIE PROTEIN)		 4j1v MOB KINASE ACTIVATOR
1A
(Homo
sapiens) 		5 / 12 PHE A 188
GLU A 192
VAL A 190
LEU A 195
ILE A 196
 None
 1.05A 6ectA-4j1vA:
undetectable		 6ectA-4j1vA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_Q_PCFQ202_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4j1v MOB KINASE ACTIVATOR
1A
(Homo
sapiens) 		4 / 6 TYR A 114
ILE A 115
ALA A 160
ARG A 157
 None
 1.11A 6hu9m-4j1vA:
1.6
6hu9q-4j1vA:
undetectable		 6hu9m-4j1vA:
16.44
6hu9q-4j1vA:
23.40