SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4j2f'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRQ_B_ERYB195_0
(REPRESSOR PROTEIN
MPHR(A))		 4j2f GLUTATHIONE
S-TRANSFERASE
(Ricinus
communis) 		5 / 12 LEU A 202
GLY A 160
SER A  67
ILE A 198
VAL A  98
 None
 0.95A 3frqB-4j2fA:
undetectable		 3frqB-4j2fA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VLN_A_ASCA904_0
(GLUTATHIONE
S-TRANSFERASE
OMEGA-1)		 4j2f GLUTATHIONE
S-TRANSFERASE
(Ricinus
communis) 		5 / 6 PHE A  15
ARG A  18
PRO A  55
GLU A  66
SER A  67
 None
 0.46A 3vlnA-4j2fA:
23.7		 3vlnA-4j2fA:
27.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_B_LNLB701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4j2f GLUTATHIONE
S-TRANSFERASE
(Ricinus
communis) 		5 / 12 ARG A 216
GLY A 173
ALA A 172
GLY A 166
LEU A 165
 None
 0.88A 4e1gB-4j2fA:
undetectable		 4e1gB-4j2fA:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7C_A_ACTA504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 4j2f GLUTATHIONE
S-TRANSFERASE
(Ricinus
communis) 		3 / 3 ARG A  18
TRP A 164
GLY A 160
 None
 0.85A 4e7cA-4j2fA:
undetectable		 4e7cA-4j2fA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_C_29SC601_2
(ESTROGEN RECEPTOR)		 4j2f GLUTATHIONE
S-TRANSFERASE
(Ricinus
communis) 		4 / 6 LEU A  71
GLU A  66
ILE A  20
PRO A  63
 None
 0.98A 4xi3C-4j2fA:
undetectable		 4xi3C-4j2fA:
22.05