SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4j2o'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_B_9CRB165_2
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)		 4j2o UDP-N-ACETYLGLUCOSAM
INE
4,6-DEHYDRATASE/5-EP
IMERASE
(Acinetobacter
baumannii) 		4 / 8 ALA A 273
PHE A 280
VAL A 282
VAL A 223
 None
 0.67A 1epbB-4j2oA:
undetectable		 1epbB-4j2oA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R9O_A_FLPA501_1
(CYTOCHROME P450 2C9)		 4j2o UDP-N-ACETYLGLUCOSAM
INE
4,6-DEHYDRATASE/5-EP
IMERASE
(Acinetobacter
baumannii) 		5 / 12 VAL A  61
ILE A   9
LEU A   8
VAL A 119
ALA A  81
 NAP  A 400 (-3.5A)
None
None
None
NAP  A 400 (-3.4A)
 1.07A 1r9oA-4j2oA:
undetectable		 1r9oA-4j2oA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QX3_A_EVPA1_1
(DNA TOPOISOMERASE
2-BETA)		 4j2o UDP-N-ACETYLGLUCOSAM
INE
4,6-DEHYDRATASE/5-EP
IMERASE
(Acinetobacter
baumannii) 		4 / 5 GLY A 165
ASP A 125
ARG A 197
GLN A  85
 NAP  A 400 (-4.2A)
None
None
None
 1.13A 3qx3A-4j2oA:
undetectable		 3qx3A-4j2oA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QX3_D_EVPD1_1
(DNA TOPOISOMERASE
2-BETA)		 4j2o UDP-N-ACETYLGLUCOSAM
INE
4,6-DEHYDRATASE/5-EP
IMERASE
(Acinetobacter
baumannii) 		4 / 5 GLY A 165
ASP A 125
ARG A 197
GLN A  85
 NAP  A 400 (-4.2A)
None
None
None
 1.26A 3qx3B-4j2oA:
undetectable		 3qx3B-4j2oA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKA_A_SAMA400_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE H)		 4j2o UDP-N-ACETYLGLUCOSAM
INE
4,6-DEHYDRATASE/5-EP
IMERASE
(Acinetobacter
baumannii) 		5 / 12 GLY A  11
HIS A  79
SER A  36
GLN A  42
GLU A  31
 NAP  A 400 (-3.3A)
None
NAP  A 400 (-3.0A)
None
None
 1.33A 3tkaA-4j2oA:
9.6		 3tkaA-4j2oA:
26.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKA_A_SAMA400_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE H)		 4j2o UDP-N-ACETYLGLUCOSAM
INE
4,6-DEHYDRATASE/5-EP
IMERASE
(Acinetobacter
baumannii) 		5 / 12 GLY A  12
HIS A  79
SER A  36
GLN A  42
GLU A  31
 None
None
NAP  A 400 (-3.0A)
None
None
 1.31A 3tkaA-4j2oA:
9.6		 3tkaA-4j2oA:
26.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TQB_A_FOLA2001_0
(DIHYDROFOLATE
REDUCTASE)		 4j2o UDP-N-ACETYLGLUCOSAM
INE
4,6-DEHYDRATASE/5-EP
IMERASE
(Acinetobacter
baumannii) 		5 / 11 LEU A 122
THR A  10
ILE A   9
LEU A   7
ILE A  77
 NAP  A 400 (-4.1A)
None
None
None
None
 1.09A 3tqbA-4j2oA:
2.1		 3tqbA-4j2oA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_G_ACHG301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 4j2o UDP-N-ACETYLGLUCOSAM
INE
4,6-DEHYDRATASE/5-EP
IMERASE
(Acinetobacter
baumannii) 		4 / 8 THR A 230
ARG A 315
LEU A 316
MET A 321
 None
 1.22A 3wipG-4j2oA:
undetectable
3wipH-4j2oA:
undetectable		 3wipG-4j2oA:
23.08
3wipH-4j2oA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJV_A_RITA500_2
(PROTEASE)		 4j2o UDP-N-ACETYLGLUCOSAM
INE
4,6-DEHYDRATASE/5-EP
IMERASE
(Acinetobacter
baumannii) 		5 / 11 GLY A 103
ASP A  60
GLY A  11
THR A  71
ILE A  67
 None
NAP  A 400 (-3.3A)
NAP  A 400 (-3.3A)
None
None
 1.04A 4njvB-4j2oA:
undetectable		 4njvB-4j2oA:
14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYK_A_OAQA302_0
(SULFOTRANSFERASE)		 4j2o UDP-N-ACETYLGLUCOSAM
INE
4,6-DEHYDRATASE/5-EP
IMERASE
(Acinetobacter
baumannii) 		5 / 12 ILE A 175
LEU A 202
LEU A 238
THR A 201
THR A 335
 None
 1.23A 5bykA-4j2oA:
2.5		 5bykA-4j2oA:
24.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M54_B_TA1B502_1
(TUBULIN BETA-2B
CHAIN)		 4j2o UDP-N-ACETYLGLUCOSAM
INE
4,6-DEHYDRATASE/5-EP
IMERASE
(Acinetobacter
baumannii) 		5 / 12 ALA A 169
SER A 173
PHE A 330
THR A 335
LEU A 238
 None
 1.46A 5m54B-4j2oA:
6.7		 5m54B-4j2oA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4j2o UDP-N-ACETYLGLUCOSAM
INE
4,6-DEHYDRATASE/5-EP
IMERASE
(Acinetobacter
baumannii) 		4 / 6 ILE A 175
ARG A 332
THR A 335
LEU A 242
 None
 1.03A 5z86N-4j2oA:
undetectable
5z86W-4j2oA:
undetectable		 5z86N-4j2oA:
20.88
5z86W-4j2oA:
9.42