SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4j2q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW3_A_ACTA600_0
(HISTONE
METHYLTRANSFERASE
DOT1L)		 4j2q S-ARRESTIN
(Bos
taurus) 		4 / 5 LEU A  46
VAL A  44
TYR A  25
THR A 115
 None
 0.89A 1nw3A-4j2qA:
undetectable		 1nw3A-4j2qA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEI_A_CXXA802_1
(TRANSPORTER)		 4j2q S-ARRESTIN
(Bos
taurus) 		4 / 6 ARG A  66
PHE A 147
ILE A 174
PHE A 122
 None
 1.26A 2qeiA-4j2qA:
undetectable		 2qeiA-4j2qA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL4_A_ROCA100_2
(PROTEASE)		 4j2q S-ARRESTIN
(Bos
taurus) 		5 / 9 ARG A 175
ASP A 146
ALA A  64
GLY A 322
ILE A 323
 None
 1.25A 3el4B-4j2qA:
undetectable		 3el4B-4j2qA:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP6_A_B40A601_1
(TRANSPORTER)		 4j2q S-ARRESTIN
(Bos
taurus) 		4 / 5 ASP A  30
VAL A  41
ASP A  42
GLY A  27
 None
 1.14A 4xp6A-4j2qA:
undetectable		 4xp6A-4j2qA:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E4D_B_BEZB202_0
(HYDROXYNITRILE LYASE)		 4j2q S-ARRESTIN
(Bos
taurus) 		4 / 7 VAL A 325
THR A 310
LEU A 132
VAL A 145
 None
 1.00A 5e4dA-4j2qA:
undetectable
5e4dB-4j2qA:
undetectable		 5e4dA-4j2qA:
20.58
5e4dB-4j2qA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGP_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 4j2q S-ARRESTIN
(Bos
taurus) 		4 / 4 VAL A 259
VAL A 241
TYR A 327
GLN A 328
 None
 0.93A 5qgpA-4j2qA:
undetectable		 5qgpA-4j2qA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGQ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 4j2q S-ARRESTIN
(Bos
taurus) 		4 / 4 VAL A 259
VAL A 241
TYR A 327
GLN A 328
 None
 0.93A 5qgqA-4j2qA:
undetectable		 5qgqA-4j2qA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHB_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 4j2q S-ARRESTIN
(Bos
taurus) 		4 / 4 VAL A 259
VAL A 241
TYR A 327
GLN A 328
 None
 0.94A 5qhbA-4j2qA:
undetectable		 5qhbA-4j2qA:
20.32