SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4j30'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N2X_B_SAMB402_0
(S-ADENOSYL-METHYLTRA
NSFERASE MRAW)		 4j30 PUTATIVE CYTOPLASMIC
PROTEIN
(Salmonella
enterica) 		5 / 12 GLY A  24
GLY A  28
GLY A  29
VAL A  23
GLY A  38
 ETX  A 205 (-4.8A)
ETX  A 205 (-3.3A)
ETX  A 205 (-4.0A)
None
None
 0.93A 1n2xB-4j30A:
undetectable		 1n2xB-4j30A:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GEH_A_NHYA300_1
(CARBONIC ANHYDRASE 2)		 4j30 PUTATIVE CYTOPLASMIC
PROTEIN
(Salmonella
enterica) 		4 / 8 VAL A 127
VAL A 114
LEU A  87
THR A  88
 None
 0.74A 2gehA-4j30A:
undetectable		 2gehA-4j30A:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FW3_B_ETSB303_1
(CARBONIC ANHYDRASE 4)		 4j30 PUTATIVE CYTOPLASMIC
PROTEIN
(Salmonella
enterica) 		5 / 12 VAL A 127
ILE A 112
VAL A 114
LEU A  87
THR A  88
 None
 1.06A 3fw3B-4j30A:
undetectable		 3fw3B-4j30A:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVD_A_SAMA502_0
(D-MYCAROSE
3-C-METHYLTRANSFERAS
E)		 4j30 PUTATIVE CYTOPLASMIC
PROTEIN
(Salmonella
enterica) 		5 / 12 ILE A  46
ALA A  71
HIS A  18
VAL A  23
ILE A  35
 None
None
ETX  A 204 ( 3.8A)
None
None
 1.11A 4rvdA-4j30A:
undetectable		 4rvdA-4j30A:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M0O_C_EPAC502_1
(TERMINAL
OLEFIN-FORMING FATTY
ACID DECARBOXYLASE)		 4j30 PUTATIVE PERIPLASMIC
PROTEIN
(Salmonella
enterica) 		4 / 8 LEU B 120
ILE B  83
ALA B  44
PHE B 111
 None
 1.05A 5m0oC-4j30B:
undetectable		 5m0oC-4j30B:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA503_1
(CYTOCHROME P450 2C9)		 4j30 PUTATIVE CYTOPLASMIC
PROTEIN
(Salmonella
enterica) 		4 / 5 GLY A  37
THR A  36
ASN A  34
LYS A  33
 None
ETX  A 205 ( 4.8A)
None
ETX  A 205 (-4.3A)
 1.01A 5x23A-4j30A:
undetectable		 5x23A-4j30A:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC607_0
(ALPHA-AMYLASE)		 4j30 PUTATIVE CYTOPLASMIC
PROTEIN
(Salmonella
enterica) 		4 / 6 GLY A 111
ASP A  95
GLY A 132
GLY A 108
 None
 0.67A 6ag0C-4j30A:
undetectable		 6ag0C-4j30A:
18.02