SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4j3b'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_B_803B311_1
(ANTIGEN CD11A (P180))		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		4 / 7 LEU A 982
VAL A 986
LEU A 930
LEU A 933
 None
 0.67A 1cqpA-4j3bA:
undetectable
1cqpB-4j3bA:
undetectable		 1cqpA-4j3bA:
13.06
1cqpB-4j3bA:
13.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DF7_A_MTXA501_1
(DIHYDROFOLATE
REDUCTASE)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		5 / 12 ILE A 804
ALA A 806
LEU A 827
PRO A 828
ILE A 856
 None
 0.98A 1df7A-4j3bA:
undetectable		 1df7A-4j3bA:
11.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DG5_A_TOPA201_1
(DIHYDROFOLATE
REDUCTASE)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		5 / 11 ILE A 804
ALA A 806
LEU A 827
PRO A 828
ILE A 856
 None
 1.02A 1dg5A-4j3bA:
undetectable		 1dg5A-4j3bA:
11.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GEB_A_CAMA418_0
(CYTOCHROME P450-CAM)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		5 / 9 LEU A 307
VAL A 387
ILE A 469
VAL A 454
ILE A 313
 None
 1.34A 1gebA-4j3bA:
undetectable		 1gebA-4j3bA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_C_115C4_1
(HMG-COA REDUCTASE)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		4 / 7 VAL A 586
SER A 584
ASN A 527
ASP A 581
 None
 1.37A 1hwiC-4j3bA:
undetectable		 1hwiC-4j3bA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_D_115D3_2
(HMG-COA REDUCTASE)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		4 / 7 VAL A 586
SER A 584
ASN A 527
ASP A 581
 None
 1.36A 1hwiD-4j3bA:
undetectable		 1hwiD-4j3bA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J36_A_LPRA801_1
(ANGIOTENSIN
CONVERTING ENZYME)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		5 / 12 HIS A 496
GLU A 497
HIS A 500
GLU A 519
TYR A 580
 ZN  A1102 ( 3.2A)
ARG  A1101 (-2.5A)
ZN  A1102 ( 3.2A)
ZN  A1102 ( 2.1A)
ARG  A1101 (-4.5A)
 0.71A 1j36A-4j3bA:
6.8		 1j36A-4j3bA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J36_B_LPRB802_1
(ANGIOTENSIN
CONVERTING ENZYME)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		5 / 12 HIS A 496
GLU A 497
HIS A 500
GLU A 519
TYR A 580
 ZN  A1102 ( 3.2A)
ARG  A1101 (-2.5A)
ZN  A1102 ( 3.2A)
ZN  A1102 ( 2.1A)
ARG  A1101 (-4.5A)
 0.72A 1j36B-4j3bA:
6.7		 1j36B-4j3bA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J37_A_X8ZA801_1
(ANGIOTENSIN
CONVERTING ENZYME)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		5 / 11 HIS A 496
GLU A 497
HIS A 500
GLU A 519
TYR A 580
 ZN  A1102 ( 3.2A)
ARG  A1101 (-2.5A)
ZN  A1102 ( 3.2A)
ZN  A1102 ( 2.1A)
ARG  A1101 (-4.5A)
 0.70A 1j37A-4j3bA:
3.2		 1j37A-4j3bA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J37_B_X8ZB802_1
(ANGIOTENSIN
CONVERTING ENZYME)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		5 / 11 HIS A 496
GLU A 497
HIS A 500
GLU A 519
TYR A 580
 ZN  A1102 ( 3.2A)
ARG  A1101 (-2.5A)
ZN  A1102 ( 3.2A)
ZN  A1102 ( 2.1A)
ARG  A1101 (-4.5A)
 0.70A 1j37B-4j3bA:
3.7		 1j37B-4j3bA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT3_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		4 / 7 LEU A 276
LEU A 244
MET A 233
MET A 335
 None
 1.08A 1kt3A-4j3bA:
undetectable		 1kt3A-4j3bA:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O86_A_LPRA702_1
(ANGIOTENSIN
CONVERTING ENZYME)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		5 / 12 HIS A 496
GLU A 497
HIS A 500
GLU A 519
TYR A 580
 ZN  A1102 ( 3.2A)
ARG  A1101 (-2.5A)
ZN  A1102 ( 3.2A)
ZN  A1102 ( 2.1A)
ARG  A1101 (-4.5A)
 0.67A 1o86A-4j3bA:
7.8		 1o86A-4j3bA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P33_A_MTXA351_1
(PTERIDINE REDUCTASE
1)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		5 / 12 PHE A 440
LEU A 528
TYR A 439
LEU A 521
MET A 624
 None
 1.44A 1p33A-4j3bA:
undetectable		 1p33A-4j3bA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P33_B_MTXB352_1
(PTERIDINE REDUCTASE
1)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		5 / 12 PHE A 440
LEU A 528
TYR A 439
LEU A 521
MET A 624
 None
 1.42A 1p33B-4j3bA:
undetectable		 1p33B-4j3bA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PKV_A_RBFA100_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		5 / 11 LEU A 216
THR A 342
ILE A 296
ILE A 226
VAL A 294
 None
 1.20A 1pkvA-4j3bA:
undetectable
1pkvB-4j3bA:
undetectable		 1pkvA-4j3bA:
8.29
1pkvB-4j3bA:
8.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PKV_B_RBFB101_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		5 / 11 ILE A 226
VAL A 294
LEU A 216
THR A 342
ILE A 296
 None
 1.20A 1pkvA-4j3bA:
undetectable
1pkvB-4j3bA:
undetectable		 1pkvA-4j3bA:
8.29
1pkvB-4j3bA:
8.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZLQ_B_ACTB1505_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		4 / 4 ASN A 610
LYS A 608
LYS A 609
TYR A 606
 None
 1.38A 1zlqB-4j3bA:
1.3		 1zlqB-4j3bA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_A_SAMA301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		3 / 3 LYS A 380
ASP A 358
ASN A 356
 None
 1.19A 2bm9A-4j3bA:
undetectable		 2bm9A-4j3bA:
14.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C6N_A_LPRA705_1
(ANGIOTENSIN-CONVERTI
NG ENZYME, SOMATIC
ISOFORM)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		6 / 12 ALA A 461
HIS A 496
GLU A 497
HIS A 500
GLU A 519
TYR A 580
 None
ZN  A1102 ( 3.2A)
ARG  A1101 (-2.5A)
ZN  A1102 ( 3.2A)
ZN  A1102 ( 2.1A)
ARG  A1101 (-4.5A)
 0.66A 2c6nA-4j3bA:
6.9		 2c6nA-4j3bA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C6N_B_LPRB705_1
(ANGIOTENSIN-CONVERTI
NG ENZYME, SOMATIC
ISOFORM)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		5 / 12 HIS A 496
GLU A 497
HIS A 500
GLU A 519
TYR A 580
 ZN  A1102 ( 3.2A)
ARG  A1101 (-2.5A)
ZN  A1102 ( 3.2A)
ZN  A1102 ( 2.1A)
ARG  A1101 (-4.5A)
 0.70A 2c6nB-4j3bA:
7.4		 2c6nB-4j3bA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA6_A_SCKA902_1
(ACETYLCHOLINESTERASE)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		5 / 10 ASN A 458
GLU A 957
LEU A 958
LEU A 476
TYR A 418
 None
 1.42A 2ha6A-4j3bA:
undetectable		 2ha6A-4j3bA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA6_B_SCKB952_1
(ACETYLCHOLINESTERASE)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		5 / 10 ASN A 458
GLU A 957
LEU A 958
LEU A 476
TYR A 418
 None
 1.43A 2ha6B-4j3bA:
undetectable		 2ha6B-4j3bA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_C_SAMC1003_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		5 / 12 HIS A 920
ALA A 818
ALA A 875
GLY A 819
TYR A 865
 None
 1.30A 2igtC-4j3bA:
undetectable		 2igtC-4j3bA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_A_SC2A1290_1
(FICOLIN-2)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		4 / 5 ASP A1012
SER A1014
LEU A1020
GLY A1017
 None
 1.19A 2j2pA-4j3bA:
undetectable
2j2pB-4j3bA:
undetectable		 2j2pA-4j3bA:
13.42
2j2pB-4j3bA:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNH_B_9CRB501_1
(CYTOCHROME P450 2C8)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		5 / 9 GLY A 357
THR A 327
VAL A 341
ILE A 218
VAL A 227
 None
 1.32A 2nnhB-4j3bA:
undetectable		 2nnhB-4j3bA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYM_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		5 / 12 LEU A 251
GLY A 306
ILE A 220
VAL A 294
ILE A 296
 None
 0.91A 2pymB-4j3bA:
undetectable		 2pymB-4j3bA:
7.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYN_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		5 / 12 LEU A 251
GLY A 306
ILE A 220
VAL A 294
ILE A 296
 None
 0.93A 2pynB-4j3bA:
undetectable		 2pynB-4j3bA:
7.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		5 / 12 LEU A 251
GLY A 306
ILE A 220
VAL A 294
ILE A 296
 None
 0.90A 2q63B-4j3bA:
undetectable		 2q63B-4j3bA:
8.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		5 / 12 LEU A 251
GLY A 306
ILE A 220
VAL A 294
ILE A 296
 None
 0.92A 2qakB-4j3bA:
undetectable		 2qakB-4j3bA:
8.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X8Z_A_X8ZA1615_1
(ANGIOTENSIN
CONVERTING ENZYME)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		5 / 11 HIS A 496
GLU A 497
HIS A 500
GLU A 519
TYR A 580
 ZN  A1102 ( 3.2A)
ARG  A1101 (-2.5A)
ZN  A1102 ( 3.2A)
ZN  A1102 ( 2.1A)
ARG  A1101 (-4.5A)
 0.61A 2x8zA-4j3bA:
7.9		 2x8zA-4j3bA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X91_A_LPRA1615_1
(ANGIOTENSIN
CONVERTING ENZYME)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		5 / 12 HIS A 496
GLU A 497
HIS A 500
GLU A 519
TYR A 580
 ZN  A1102 ( 3.2A)
ARG  A1101 (-2.5A)
ZN  A1102 ( 3.2A)
ZN  A1102 ( 2.1A)
ARG  A1101 (-4.5A)
 0.63A 2x91A-4j3bA:
7.5		 2x91A-4j3bA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_E_ACHE1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		4 / 7 ILE A 326
SER A 355
TYR A 339
CYH A 318
 None
 1.32A 2xz5D-4j3bA:
1.8
2xz5E-4j3bA:
1.5		 2xz5D-4j3bA:
12.83
2xz5E-4j3bA:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APX_A_Z80A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		5 / 12 PHE A 552
PHE A 656
LEU A 712
ALA A 738
PHE A 733
 None
 1.32A 3apxA-4j3bA:
undetectable		 3apxA-4j3bA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_2
(PHOSPHOLIPASE A2)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		4 / 8 TYR A1077
ASN A1073
PRO A 459
PHE A 457
 None
None
ARG  A1101 (-3.9A)
None
 1.21A 3bjwD-4j3bA:
undetectable		 3bjwD-4j3bA:
9.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1X_A_ROCA201_2
(HIV-1 PROTEASE)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		5 / 12 LEU A 251
GLY A 306
ILE A 220
VAL A 294
ILE A 296
 None
 0.93A 3d1xB-4j3bA:
undetectable		 3d1xB-4j3bA:
7.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HKU_A_TORA300_2
(CARBONIC ANHYDRASE 2)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		3 / 3 GLU A 554
HIS A 561
THR A 576
 None
 0.89A 3hkuA-4j3bA:
undetectable		 3hkuA-4j3bA:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JVY_B_017B401_2
(GAG-POL POLYPROTEIN)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		5 / 12 LEU A 251
GLY A 306
ILE A 220
VAL A 294
ILE A 296
 None
 0.93A 3jvyB-4j3bA:
undetectable		 3jvyB-4j3bA:
7.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K37_B_BCZB468_1
(NEURAMINIDASE)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		3 / 3 ARG A 831
GLU A 554
TYR A1077
 None
 0.93A 3k37B-4j3bA:
undetectable		 3k37B-4j3bA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPB_C_SAMC1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		5 / 12 LYS A1044
THR A 576
VAL A 579
ILE A 563
SER A 649
 None
 1.23A 3kpbC-4j3bA:
undetectable		 3kpbC-4j3bA:
8.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPB_D_SAMD1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		5 / 10 LYS A1044
THR A 576
VAL A 579
ILE A 563
SER A 649
 None
 1.27A 3kpbD-4j3bA:
undetectable		 3kpbD-4j3bA:
8.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBG_A_ACTA206_0
(FAD-LINKED
SULFHYDRYL OXIDASE
ALR)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		4 / 4 ASP A 619
ARG A 510
THR A 614
ALA A 615
 None
 1.40A 3mbgA-4j3bA:
0.1		 3mbgA-4j3bA:
9.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_D_ROCD100_1
(PROTEASE)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		5 / 12 LEU A 251
GLY A 306
ILE A 220
VAL A 294
ILE A 296
 None
 0.86A 3ndtC-4j3bA:
undetectable		 3ndtC-4j3bA:
7.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_A_ROCA101_1
(PROTEASE)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		5 / 12 LEU A 251
GLY A 306
ILE A 220
VAL A 294
ILE A 296
 None
 0.93A 3nduA-4j3bA:
undetectable		 3nduA-4j3bA:
7.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_A_ROCA101_2
(PROTEASE)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		5 / 12 LEU A 251
GLY A 306
ILE A 220
VAL A 294
ILE A 296
 None
 0.91A 3nduB-4j3bA:
undetectable		 3nduB-4j3bA:
7.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_D_ROCD100_1
(PROTEASE)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		5 / 12 LEU A 251
GLY A 306
ILE A 220
VAL A 294
ILE A 296
 None
 0.88A 3nduC-4j3bA:
undetectable		 3nduC-4j3bA:
7.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_C_SAMC6735_1
(16S RRNA METHYLASE)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		4 / 5 ASN A 473
GLU A 554
THR A 576
SER A 474
 None
 1.43A 3p2kC-4j3bA:
undetectable		 3p2kC-4j3bA:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWR_A_ROCA401_3
(PROTEASE)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		5 / 12 LEU A 251
GLY A 306
ILE A 220
VAL A 294
ILE A 296
 None
 0.95A 3pwrB-4j3bA:
undetectable		 3pwrB-4j3bA:
7.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R0L_D_ACTD127_0
(PHOSPHOLIPASE A2 CB)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		4 / 5 PHE A1010
ILE A1021
GLY A1015
HIS A1011
 None
 1.37A 3r0lD-4j3bA:
undetectable		 3r0lD-4j3bA:
8.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RV5_C_DXCC92_0
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		4 / 4 VAL A 294
PHE A 328
PHE A 329
VAL A 214
 None
 1.13A 3rv5C-4j3bA:
0.3
3rv5D-4j3bA:
0.2		 3rv5C-4j3bA:
7.56
3rv5D-4j3bA:
7.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S56_A_ROCA201_2
(PROTEASE)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		5 / 9 ASP A 346
GLY A 390
ILE A 313
ILE A 218
ILE A 220
 None
 1.00A 3s56B-4j3bA:
undetectable		 3s56B-4j3bA:
6.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_C_SUEC1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		4 / 5 TYR A1018
ILE A 978
LEU A 982
LYS A 980
 None
 1.28A 3sueC-4j3bA:
undetectable		 3sueC-4j3bA:
13.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_B_ROCB801_1
(PROTEASE)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		5 / 12 LEU A 251
GLY A 306
ILE A 220
VAL A 294
ILE A 296
 None
 0.90A 3tkgA-4j3bA:
undetectable		 3tkgA-4j3bA:
8.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9H_A_NCAA1163_0
(TANKYRASE-2)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		4 / 8 GLY A 595
TYR A 590
ALA A 627
TYR A 599
 None
 0.83A 3u9hA-4j3bA:
undetectable		 3u9hA-4j3bA:
13.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9H_B_NCAB1164_0
(TANKYRASE-2)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		4 / 8 GLY A 595
TYR A 590
ALA A 627
TYR A 599
 None
 0.84A 3u9hB-4j3bA:
undetectable		 3u9hB-4j3bA:
13.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BLV_A_SAMA1281_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		5 / 12 TYR A 667
ASP A 758
GLY A 694
GLY A 701
PRO A 728
 None
 1.18A 4blvA-4j3bA:
undetectable		 4blvA-4j3bA:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C2P_A_X8ZA709_1
(ANGIOTENSIN-CONVERTI
NG ENZYME)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		5 / 11 HIS A 496
GLU A 497
HIS A 500
GLU A 519
TYR A 580
 ZN  A1102 ( 3.2A)
ARG  A1101 (-2.5A)
ZN  A1102 ( 3.2A)
ZN  A1102 ( 2.1A)
ARG  A1101 (-4.5A)
 0.70A 4c2pA-4j3bA:
7.8		 4c2pA-4j3bA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DPR_A_X8ZA702_1
(LEUKOTRIENE A-4
HYDROLASE)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		5 / 9 GLY A 460
HIS A 496
GLU A 497
GLU A 519
TYR A 580
 None
ZN  A1102 ( 3.2A)
ARG  A1101 (-2.5A)
ZN  A1102 ( 2.1A)
ARG  A1101 (-4.5A)
 0.31A 4dprA-4j3bA:
22.4		 4dprA-4j3bA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DRJ_A_RAPA201_2
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP4
SERINE/THREONINE-PRO
TEIN KINASE MTOR)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		4 / 8 LEU A 901
ASP A 862
TYR A 865
PHE A 868
 None
 0.61A 4drjB-4j3bA:
undetectable		 4drjB-4j3bA:
7.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVQ_A_ACTA904_0
(TYROSINE-PROTEIN
KINASE JAK2)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		3 / 3 PHE A 762
VAL A 544
GLU A 585
 None
 0.81A 4fvqA-4j3bA:
undetectable		 4fvqA-4j3bA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IV0_A_SAMA302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		5 / 12 ILE A1013
GLY A1017
GLY A1015
ILE A1021
ARG A1009
 None
 1.00A 4iv0A-4j3bA:
undetectable		 4iv0A-4j3bA:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IV0_B_SAMB302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		5 / 12 ILE A1013
GLY A1017
GLY A1015
ILE A1021
ARG A1009
 None
 0.99A 4iv0B-4j3bA:
undetectable		 4iv0B-4j3bA:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOE_F_TR6F101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B
E-SITE DNA2)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		4 / 6 SER A 316
GLY A 357
ASP A 376
GLY A 466
 None
 0.94A 4koeA-4j3bA:
2.1
4koeB-4j3bA:
undetectable
4koeC-4j3bA:
undetectable		 4koeA-4j3bA:
19.82
4koeB-4j3bA:
19.82
4koeC-4j3bA:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOE_H_TR6H101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B
E-SITE DNA4)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		4 / 7 SER A 316
GLY A 357
ASP A 376
GLY A 466
 None
 0.87A 4koeA-4j3bA:
2.1
4koeB-4j3bA:
undetectable
4koeD-4j3bA:
undetectable		 4koeA-4j3bA:
19.82
4koeB-4j3bA:
19.82
4koeD-4j3bA:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_A_SAMA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		5 / 12 ILE A1013
GLY A1017
GLY A1015
ILE A1021
ARG A1009
 None
 1.00A 4mwzA-4j3bA:
undetectable		 4mwzA-4j3bA:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_B_SAMB301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		5 / 12 ILE A1013
GLY A1017
GLY A1015
ILE A1021
ARG A1009
 None
 1.01A 4mwzB-4j3bA:
undetectable		 4mwzB-4j3bA:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_A_DAHA304_1
(TYROSINASE)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		4 / 5 ASN A 527
HIS A 543
GLU A 526
THR A 492
 None
 1.25A 4p6sA-4j3bA:
undetectable		 4p6sA-4j3bA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PAE_A_NIZA804_1
(CATALASE-PEROXIDASE)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		4 / 6 PHE A 603
ASP A 436
TYR A 439
THR A 503
 None
 1.35A 4paeA-4j3bA:
undetectable		 4paeA-4j3bA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R7L_A_SHHA709_1
(LEUKOTRIENE A-4
HYDROLASE)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		7 / 12 ALA A 320
HIS A 496
GLU A 497
HIS A 500
TRP A 512
GLU A 519
TYR A 580
 None
ZN  A1102 ( 3.2A)
ARG  A1101 (-2.5A)
ZN  A1102 ( 3.2A)
None
ZN  A1102 ( 2.1A)
ARG  A1101 (-4.5A)
 0.32A 4r7lA-4j3bA:
22.1		 4r7lA-4j3bA:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z53_F_TR6F101_1
(DNA TOPOISOMERASE 4
SUBUNIT B,DNA
TOPOISOMERASE 4
SUBUNIT A
E-SITE DNA)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		4 / 6 GLY A 357
ASP A 376
GLY A 466
SER A 316
 None
 0.95A 4z53A-4j3bA:
undetectable
4z53B-4j3bA:
undetectable		 4z53A-4j3bA:
22.89
4z53B-4j3bA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z53_H_TR6H101_1
(DNA TOPOISOMERASE 4
SUBUNIT B,DNA
TOPOISOMERASE 4
SUBUNIT A
E-SITE DNA)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		4 / 7 GLY A 357
ASP A 376
GLY A 466
SER A 316
 None
 0.86A 4z53A-4j3bA:
undetectable
4z53B-4j3bA:
undetectable		 4z53A-4j3bA:
22.89
4z53B-4j3bA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1R_A_STRA600_1
(CYTOCHROME P450 3A4)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		4 / 5 PHE A 733
ASP A 744
PHE A 656
VAL A 654
 None
 1.16A 5a1rA-4j3bA:
undetectable		 5a1rA-4j3bA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BW4_B_SAMB301_1
(16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		3 / 3 ASP A 581
GLU A1041
SER A 530
 None
 0.87A 5bw4B-4j3bA:
undetectable		 5bw4B-4j3bA:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGV_A_ZITA404_2
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		4 / 4 ASN A 468
ILE A 314
TYR A 308
PHE A 323
 None
 1.45A 5igvA-4j3bA:
undetectable		 5igvA-4j3bA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LRB_A_ACRA1003_1
(ALPHA-1,4 GLUCAN
PHOSPHORYLASE)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		4 / 6 GLU A 319
PHE A 574
THR A 576
TYR A 575
 ARG  A1101 (-2.9A)
None
None
ARG  A1101 ( 3.8A)
 1.18A 5lrbA-4j3bA:
undetectable		 5lrbA-4j3bA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZJ_A_TEPA2401_1
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		4 / 8 LEU A 901
GLU A 812
LEU A 860
ILE A 807
 None
 1.00A 5mzjA-4j3bA:
undetectable		 5mzjA-4j3bA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5PAH_A_LDPA600_1
(PHENYLALANINE
4-MONOOXYGENASE)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		4 / 4 HIS A 500
HIS A 496
TYR A 580
GLU A 519
 ZN  A1102 ( 3.2A)
ZN  A1102 ( 3.2A)
ARG  A1101 (-4.5A)
ZN  A1102 ( 2.1A)
 1.43A 5pahA-4j3bA:
undetectable		 5pahA-4j3bA:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V1S_A_SAMA604_0
(RADICAL SAM)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		5 / 9 THR A 539
SER A 530
ASN A 527
VAL A 523
TYR A 580
 None
None
None
None
ARG  A1101 (-4.5A)
 1.41A 5v1sA-4j3bA:
0.0		 5v1sA-4j3bA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V1S_B_SAMB604_0
(RADICAL SAM)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		5 / 9 THR A 539
SER A 530
ASN A 527
VAL A 523
TYR A 580
 None
None
None
None
ARG  A1101 (-4.5A)
 1.46A 5v1sB-4j3bA:
0.0		 5v1sB-4j3bA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V1T_A_SAMA605_0
(RADICAL SAM)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		5 / 12 THR A 539
SER A 530
ASN A 527
VAL A 523
TYR A 580
 None
None
None
None
ARG  A1101 (-4.5A)
 1.43A 5v1tA-4j3bA:
undetectable		 5v1tA-4j3bA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_B_8LXB501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		5 / 12 PHE A 736
ILE A 691
ILE A 729
LEU A 746
ILE A 742
 None
 1.15A 5y2tB-4j3bA:
undetectable		 5y2tB-4j3bA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZV2_A_LEVA801_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		3 / 3 LYS A 981
LEU A 933
ASP A 947
 None
 0.81A 5zv2A-4j3bA:
undetectable		 5zv2A-4j3bA:
6.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZW2_A_ACTA511_0
(L-PROLYL-[PEPTIDYL-C
ARRIER PROTEIN]
DEHYDROGENASE)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		3 / 3 ARG A 751
ILE A 771
SER A 767
 None
 0.79A 5zw2A-4j3bA:
undetectable		 5zw2A-4j3bA:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_C_FK5C201_0
(PEPTIDYLPROLYL
ISOMERASE)		 4j3b M1 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		4 / 4 ASP A 717
ILE A 691
PRO A 690
LEU A 712
 None
 1.47A 6mkeB-4j3bA:
undetectable		 6mkeB-4j3bA:
6.36