SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4j40'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM3_B_478B200_1
(PROTEASE)		 4j40 FIMX
(Pseudomonas
aeruginosa) 		5 / 10 LEU A 447
GLY A 501
ALA A 500
VAL A 443
ILE A 444
 None
 0.88A 3em3A-4j40A:
undetectable		 3em3A-4j40A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_C_ADNC438_2
(ADENOSYLHOMOCYSTEINA
SE)		 4j40 FIMX
(Pseudomonas
aeruginosa) 		4 / 5 GLN A 583
THR A 582
THR A 572
HIS A 609
 None
 1.12A 3g1uC-4j40A:
2.1		 3g1uC-4j40A:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_B_478B200_1
(HIV-1 PROTEASE)		 4j40 FIMX
(Pseudomonas
aeruginosa) 		5 / 9 LEU A 447
GLY A 501
ALA A 500
VAL A 443
ILE A 444
 None
 0.82A 3oxvA-4j40A:
undetectable		 3oxvA-4j40A:
16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5O_A_IPHA906_0
(PROTEIN ARGONAUTE-2)		 4j40 FIMX
(Pseudomonas
aeruginosa) 		4 / 5 PHE A 531
PRO A 462
VAL A 463
PHE A 686
 None
 0.76A 4w5oA-4j40A:
undetectable		 4w5oA-4j40A:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 4j40 FIMX
(Pseudomonas
aeruginosa) 		4 / 5 PHE A 531
PRO A 462
VAL A 463
PHE A 686
 None
 0.75A 4z4cA-4j40A:
undetectable		 4z4cA-4j40A:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4D_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 4j40 FIMX
(Pseudomonas
aeruginosa) 		4 / 5 PHE A 531
PRO A 462
VAL A 463
PHE A 686
 None
 0.77A 4z4dA-4j40A:
undetectable		 4z4dA-4j40A:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4E_A_IPHA906_0
(PROTEIN ARGONAUTE-2)		 4j40 FIMX
(Pseudomonas
aeruginosa) 		4 / 5 PHE A 531
PRO A 462
VAL A 463
PHE A 686
 None
 0.78A 4z4eA-4j40A:
undetectable		 4z4eA-4j40A:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T7B_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 4j40 FIMX
(Pseudomonas
aeruginosa) 		4 / 6 PHE A 531
PRO A 462
VAL A 463
PHE A 686
 None
 0.74A 5t7bA-4j40A:
undetectable		 5t7bA-4j40A:
19.40