SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4j4m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS2_A_HAEA874_1
(MACROPHAGE
METALLOELASTASE)		 4j4m ZINC-DEPENDENT
METALLOPROTEINASE
(Protobothrops
mucrosquamatus) 		4 / 5 HIS A 144
GLU A 145
HIS A 148
HIS A 154
 ZN  A 301 (-3.3A)
ZN  A 301 ( 4.6A)
ZN  A 301 (-3.2A)
ZN  A 301 (-3.2A)
 0.15A 1os2A-4j4mA:
10.9		 1os2A-4j4mA:
24.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS2_D_HAED574_1
(MACROPHAGE
METALLOELASTASE)		 4j4m ZINC-DEPENDENT
METALLOPROTEINASE
(Protobothrops
mucrosquamatus) 		4 / 4 HIS A 144
GLU A 145
HIS A 148
HIS A 154
 ZN  A 301 (-3.3A)
ZN  A 301 ( 4.6A)
ZN  A 301 (-3.2A)
ZN  A 301 (-3.2A)
 0.14A 1os2D-4j4mA:
11.0		 1os2D-4j4mA:
24.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1R55_A_097A518_1
(ADAM 33)		 4j4m ZINC-DEPENDENT
METALLOPROTEINASE
(Protobothrops
mucrosquamatus) 		5 / 10 THR A 109
HIS A 144
GLU A 145
HIS A 148
ALA A 171
 None
ZN  A 301 (-3.3A)
ZN  A 301 ( 4.6A)
ZN  A 301 (-3.2A)
None
 1.09A 1r55A-4j4mA:
31.1		 1r55A-4j4mA:
34.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1R55_A_097A518_1
(ADAM 33)		 4j4m ZINC-DEPENDENT
METALLOPROTEINASE
(Protobothrops
mucrosquamatus) 		7 / 10 THR A 109
THR A 141
HIS A 144
GLU A 145
HIS A 148
HIS A 154
ALA A 170
 None
None
ZN  A 301 (-3.3A)
ZN  A 301 ( 4.6A)
ZN  A 301 (-3.2A)
ZN  A 301 (-3.2A)
None
 0.27A 1r55A-4j4mA:
31.1		 1r55A-4j4mA:
34.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTT_A_HAEA1265_1
(MACROPHAGE
METALLOELASTASE)		 4j4m ZINC-DEPENDENT
METALLOPROTEINASE
(Protobothrops
mucrosquamatus) 		4 / 4 HIS A 144
GLU A 145
HIS A 148
HIS A 154
 ZN  A 301 (-3.3A)
ZN  A 301 ( 4.6A)
ZN  A 301 (-3.2A)
ZN  A 301 (-3.2A)
 0.12A 1uttA-4j4mA:
9.4		 1uttA-4j4mA:
24.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTZ_A_HAEA1267_1
(MACROPHAGE
METALLOELASTASE)		 4j4m ZINC-DEPENDENT
METALLOPROTEINASE
(Protobothrops
mucrosquamatus) 		4 / 4 HIS A 144
GLU A 145
HIS A 148
HIS A 154
 ZN  A 301 (-3.3A)
ZN  A 301 ( 4.6A)
ZN  A 301 (-3.2A)
ZN  A 301 (-3.2A)
 0.16A 1utzA-4j4mA:
11.1		 1utzA-4j4mA:
24.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTZ_B_HAEB1266_1
(MACROPHAGE
METALLOELASTASE)		 4j4m ZINC-DEPENDENT
METALLOPROTEINASE
(Protobothrops
mucrosquamatus) 		4 / 4 HIS A 144
GLU A 145
HIS A 148
HIS A 154
 ZN  A 301 (-3.3A)
ZN  A 301 ( 4.6A)
ZN  A 301 (-3.2A)
ZN  A 301 (-3.2A)
 0.16A 1utzB-4j4mA:
11.2		 1utzB-4j4mA:
24.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UUJ_B_ACTB1077_0
(PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
ALPHA SUBUNIT)		 4j4m ZINC-DEPENDENT
METALLOPROTEINASE
(Protobothrops
mucrosquamatus) 		3 / 3 ARG A  34
TYR A  24
LYS A  23
 None
 0.97A 1uujB-4j4mA:
undetectable		 1uujB-4j4mA:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y93_A_HAEA301_1
(MACROPHAGE
METALLOELASTASE)		 4j4m ZINC-DEPENDENT
METALLOPROTEINASE
(Protobothrops
mucrosquamatus) 		4 / 6 HIS A 144
GLU A 145
HIS A 148
HIS A 154
 ZN  A 301 (-3.3A)
ZN  A 301 ( 4.6A)
ZN  A 301 (-3.2A)
ZN  A 301 (-3.2A)
 0.15A 1y93A-4j4mA:
11.3		 1y93A-4j4mA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZLQ_A_ACTA1502_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 4j4m ZINC-DEPENDENT
METALLOPROTEINASE
(Protobothrops
mucrosquamatus) 		4 / 5 PRO A 196
GLY A 117
ASN A 116
GLY A 151
 None
 1.18A 1zlqA-4j4mA:
undetectable		 1zlqA-4j4mA:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HU6_A_HAEA269_1
(MACROPHAGE
METALLOELASTASE)		 4j4m ZINC-DEPENDENT
METALLOPROTEINASE
(Protobothrops
mucrosquamatus) 		4 / 4 HIS A 144
GLU A 145
HIS A 148
HIS A 154
 ZN  A 301 (-3.3A)
ZN  A 301 ( 4.6A)
ZN  A 301 (-3.2A)
ZN  A 301 (-3.2A)
 0.09A 2hu6A-4j4mA:
11.2		 2hu6A-4j4mA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JIH_A_097A1001_1
(ADAMTS-1)		 4j4m ZINC-DEPENDENT
METALLOPROTEINASE
(Protobothrops
mucrosquamatus) 		5 / 9 THR A 141
HIS A 144
GLU A 145
HIS A 148
HIS A 154
 None
ZN  A 301 (-3.3A)
ZN  A 301 ( 4.6A)
ZN  A 301 (-3.2A)
ZN  A 301 (-3.2A)
 0.25A 2jihA-4j4mA:
26.5		 2jihA-4j4mA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JIH_B_097B1001_1
(ADAMTS-1)		 4j4m ZINC-DEPENDENT
METALLOPROTEINASE
(Protobothrops
mucrosquamatus) 		5 / 8 THR A 141
HIS A 144
GLU A 145
HIS A 148
HIS A 154
 None
ZN  A 301 (-3.3A)
ZN  A 301 ( 4.6A)
ZN  A 301 (-3.2A)
ZN  A 301 (-3.2A)
 0.26A 2jihB-4j4mA:
26.5		 2jihB-4j4mA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OW9_A_HAEA502_1
(COLLAGENASE 3)		 4j4m ZINC-DEPENDENT
METALLOPROTEINASE
(Protobothrops
mucrosquamatus) 		4 / 6 HIS A 144
GLU A 145
HIS A 148
HIS A 154
 ZN  A 301 (-3.3A)
ZN  A 301 ( 4.6A)
ZN  A 301 (-3.2A)
ZN  A 301 (-3.2A)
 0.20A 2ow9A-4j4mA:
10.9		 2ow9A-4j4mA:
26.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OW9_B_HAEB502_1
(COLLAGENASE 3)		 4j4m ZINC-DEPENDENT
METALLOPROTEINASE
(Protobothrops
mucrosquamatus) 		4 / 4 HIS A 144
GLU A 145
HIS A 148
HIS A 154
 ZN  A 301 (-3.3A)
ZN  A 301 ( 4.6A)
ZN  A 301 (-3.2A)
ZN  A 301 (-3.2A)
 0.19A 2ow9B-4j4mA:
10.7		 2ow9B-4j4mA:
26.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_C_HAEC3001_1
(COLLAGENASE 3)		 4j4m ZINC-DEPENDENT
METALLOPROTEINASE
(Protobothrops
mucrosquamatus) 		4 / 4 HIS A 144
GLU A 145
HIS A 148
HIS A 154
 ZN  A 301 (-3.3A)
ZN  A 301 ( 4.6A)
ZN  A 301 (-3.2A)
ZN  A 301 (-3.2A)
 0.20A 2ozrC-4j4mA:
10.5		 2ozrC-4j4mA:
26.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_D_HAED3002_1
(COLLAGENASE 3)		 4j4m ZINC-DEPENDENT
METALLOPROTEINASE
(Protobothrops
mucrosquamatus) 		4 / 4 HIS A 144
GLU A 145
HIS A 148
HIS A 154
 ZN  A 301 (-3.3A)
ZN  A 301 ( 4.6A)
ZN  A 301 (-3.2A)
ZN  A 301 (-3.2A)
 0.24A 2ozrD-4j4mA:
10.5		 2ozrD-4j4mA:
26.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_E_HAEE3003_1
(COLLAGENASE 3)		 4j4m ZINC-DEPENDENT
METALLOPROTEINASE
(Protobothrops
mucrosquamatus) 		4 / 4 HIS A 144
GLU A 145
HIS A 148
HIS A 154
 ZN  A 301 (-3.3A)
ZN  A 301 ( 4.6A)
ZN  A 301 (-3.2A)
ZN  A 301 (-3.2A)
 0.27A 2ozrE-4j4mA:
10.6		 2ozrE-4j4mA:
26.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_F_HAEF3004_1
(COLLAGENASE 3)		 4j4m ZINC-DEPENDENT
METALLOPROTEINASE
(Protobothrops
mucrosquamatus) 		3 / 3 HIS A 144
HIS A 148
HIS A 154
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
ZN  A 301 (-3.2A)
 0.21A 2ozrF-4j4mA:
10.5		 2ozrF-4j4mA:
26.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HY7_A_097A801_1
(A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 5)		 4j4m ZINC-DEPENDENT
METALLOPROTEINASE
(Protobothrops
mucrosquamatus) 		5 / 9 THR A 141
HIS A 144
GLU A 145
HIS A 148
HIS A 154
 None
ZN  A 301 (-3.3A)
ZN  A 301 ( 4.6A)
ZN  A 301 (-3.2A)
ZN  A 301 (-3.2A)
 0.17A 3hy7A-4j4mA:
27.0		 3hy7A-4j4mA:
27.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HY7_B_097B801_1
(A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 5)		 4j4m ZINC-DEPENDENT
METALLOPROTEINASE
(Protobothrops
mucrosquamatus) 		5 / 9 THR A 141
HIS A 144
GLU A 145
HIS A 148
HIS A 154
 None
ZN  A 301 (-3.3A)
ZN  A 301 ( 4.6A)
ZN  A 301 (-3.2A)
ZN  A 301 (-3.2A)
 0.18A 3hy7B-4j4mA:
26.8		 3hy7B-4j4mA:
27.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEC_A_HAEA272_1
(COLLAGENASE 3)		 4j4m ZINC-DEPENDENT
METALLOPROTEINASE
(Protobothrops
mucrosquamatus) 		4 / 5 HIS A 144
GLU A 145
HIS A 148
HIS A 154
 ZN  A 301 (-3.3A)
ZN  A 301 ( 4.6A)
ZN  A 301 (-3.2A)
ZN  A 301 (-3.2A)
 0.15A 3kecA-4j4mA:
10.8		 3kecA-4j4mA:
26.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEC_B_HAEB271_1
(COLLAGENASE 3)		 4j4m ZINC-DEPENDENT
METALLOPROTEINASE
(Protobothrops
mucrosquamatus) 		3 / 3 HIS A 144
GLU A 145
HIS A 148
 ZN  A 301 (-3.3A)
ZN  A 301 ( 4.6A)
ZN  A 301 (-3.2A)
 0.11A 3kecB-4j4mA:
10.7		 3kecB-4j4mA:
26.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LIK_A_HAEA302_1
(MACROPHAGE
METALLOELASTASE)		 4j4m ZINC-DEPENDENT
METALLOPROTEINASE
(Protobothrops
mucrosquamatus) 		4 / 5 HIS A 144
GLU A 145
HIS A 148
HIS A 154
 ZN  A 301 (-3.3A)
ZN  A 301 ( 4.6A)
ZN  A 301 (-3.2A)
ZN  A 301 (-3.2A)
 0.11A 3likA-4j4mA:
11.2		 3likA-4j4mA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LIL_A_HAEA302_1
(MACROPHAGE
METALLOELASTASE)		 4j4m ZINC-DEPENDENT
METALLOPROTEINASE
(Protobothrops
mucrosquamatus) 		4 / 4 HIS A 144
GLU A 145
HIS A 148
HIS A 154
 ZN  A 301 (-3.3A)
ZN  A 301 ( 4.6A)
ZN  A 301 (-3.2A)
ZN  A 301 (-3.2A)
 0.12A 3lilA-4j4mA:
11.3		 3lilA-4j4mA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LJG_A_HAEA301_1
(MACROPHAGE
METALLOELASTASE)		 4j4m ZINC-DEPENDENT
METALLOPROTEINASE
(Protobothrops
mucrosquamatus) 		4 / 5 HIS A 144
GLU A 145
HIS A 148
HIS A 154
 ZN  A 301 (-3.3A)
ZN  A 301 ( 4.6A)
ZN  A 301 (-3.2A)
ZN  A 301 (-3.2A)
 0.12A 3ljgA-4j4mA:
11.3		 3ljgA-4j4mA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LKA_A_HAEA269_1
(MACROPHAGE
METALLOELASTASE)		 4j4m ZINC-DEPENDENT
METALLOPROTEINASE
(Protobothrops
mucrosquamatus) 		4 / 5 HIS A 144
GLU A 145
HIS A 148
HIS A 154
 ZN  A 301 (-3.3A)
ZN  A 301 ( 4.6A)
ZN  A 301 (-3.2A)
ZN  A 301 (-3.2A)
 0.13A 3lkaA-4j4mA:
11.3		 3lkaA-4j4mA:
24.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UT5_B_LOCB502_1
(TUBULIN BETA CHAIN)		 4j4m ZINC-DEPENDENT
METALLOPROTEINASE
(Protobothrops
mucrosquamatus) 		5 / 12 LEU A  49
LEU A 150
ASN A 149
MET A 118
ILE A 199
 None
 1.16A 3ut5B-4j4mA:
undetectable		 3ut5B-4j4mA:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UT5_D_LOCD502_1
(TUBULIN BETA CHAIN)		 4j4m ZINC-DEPENDENT
METALLOPROTEINASE
(Protobothrops
mucrosquamatus) 		5 / 12 LEU A  49
LEU A 150
ASN A 149
MET A 118
ILE A 199
 None
 1.15A 3ut5D-4j4mA:
undetectable		 3ut5D-4j4mA:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7B_A_HAEA1273_1
(COLLAGENASE 3)		 4j4m ZINC-DEPENDENT
METALLOPROTEINASE
(Protobothrops
mucrosquamatus) 		4 / 6 HIS A 144
GLU A 145
HIS A 148
HIS A 154
 ZN  A 301 (-3.3A)
ZN  A 301 ( 4.6A)
ZN  A 301 (-3.2A)
ZN  A 301 (-3.2A)
 0.27A 4a7bA-4j4mA:
10.5		 4a7bA-4j4mA:
26.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1I_D_LOCD502_1
(TUBULIN BETA CHAIN)		 4j4m ZINC-DEPENDENT
METALLOPROTEINASE
(Protobothrops
mucrosquamatus) 		5 / 12 LEU A  49
LEU A 150
ASN A 149
MET A 118
ILE A 199
 None
 1.06A 4x1iD-4j4mA:
undetectable		 4x1iD-4j4mA:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1Y_B_LOCB502_1
(TUBULIN BETA CHAIN)		 4j4m ZINC-DEPENDENT
METALLOPROTEINASE
(Protobothrops
mucrosquamatus) 		5 / 12 LEU A  49
LEU A 150
ASN A 149
MET A 118
ILE A 199
 None
 1.06A 4x1yB-4j4mA:
undetectable		 4x1yB-4j4mA:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1Y_D_LOCD502_2
(TUBULIN BETA CHAIN)		 4j4m ZINC-DEPENDENT
METALLOPROTEINASE
(Protobothrops
mucrosquamatus) 		5 / 12 LEU A  49
LEU A 150
ASN A 149
MET A 118
ILE A 199
 None
 1.02A 4x1yD-4j4mA:
undetectable		 4x1yD-4j4mA:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X20_D_LOCD502_2
(TUBULIN BETA CHAIN)		 4j4m ZINC-DEPENDENT
METALLOPROTEINASE
(Protobothrops
mucrosquamatus) 		5 / 11 LEU A  49
LEU A 150
ASN A 149
MET A 118
ILE A 199
 None
 1.05A 4x20D-4j4mA:
undetectable		 4x20D-4j4mA:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ITZ_B_LOCB502_1
(TUBULIN BETA-2B
CHAIN)		 4j4m ZINC-DEPENDENT
METALLOPROTEINASE
(Protobothrops
mucrosquamatus) 		5 / 12 LEU A  49
LEU A 150
ASN A 149
MET A 118
ILE A 199
 None
 1.06A 5itzB-4j4mA:
undetectable		 5itzB-4j4mA:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L8R_A_PQNA844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 4j4m ZINC-DEPENDENT
METALLOPROTEINASE
(Protobothrops
mucrosquamatus) 		5 / 9 MET A 167
PHE A 179
SER A 180
ARG A   4
LEU A  49
 None
 1.50A 5l8rA-4j4mA:
undetectable		 5l8rA-4j4mA:
14.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5J_A_HAEA306_1
(MACROPHAGE
METALLOELASTASE)		 4j4m ZINC-DEPENDENT
METALLOPROTEINASE
(Protobothrops
mucrosquamatus) 		4 / 4 HIS A 144
GLU A 145
HIS A 148
HIS A 154
 ZN  A 301 (-3.3A)
ZN  A 301 ( 4.6A)
ZN  A 301 (-3.2A)
ZN  A 301 (-3.2A)
 0.12A 5n5jA-4j4mA:
11.3		 5n5jA-4j4mA:
24.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5K_A_HAEA306_1
(MACROPHAGE
METALLOELASTASE)		 4j4m ZINC-DEPENDENT
METALLOPROTEINASE
(Protobothrops
mucrosquamatus) 		4 / 5 HIS A 144
GLU A 145
HIS A 148
HIS A 154
 ZN  A 301 (-3.3A)
ZN  A 301 ( 4.6A)
ZN  A 301 (-3.2A)
ZN  A 301 (-3.2A)
 0.14A 5n5kA-4j4mA:
11.4		 5n5kA-4j4mA:
24.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BTX_A_EDTA503_0
(SOLUTE CARRIER
FAMILY 39
(IRON-REGULATED
TRANSPORTER))		 4j4m ZINC-DEPENDENT
METALLOPROTEINASE
(Protobothrops
mucrosquamatus) 		4 / 7 SER A 124
GLY A 117
ARG A  84
LEU A  89
 None
 1.14A 6btxA-4j4mA:
undetectable		 6btxA-4j4mA:
18.82