SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4j4w'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WYG_A_SALA4005_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 4j4w NUCLEOCAPSID
(Punta
Toro
phlebovirus) 		5 / 10 LEU A 222
SER A 230
PHE A 139
THR A 232
ALA A 167
 None
 1.43A 1wygA-4j4wA:
undetectable		 1wygA-4j4wA:
11.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_A_SAMA601_0
(HYPOTHETICAL PROTEIN)		 4j4w NUCLEOCAPSID
(Punta
Toro
phlebovirus) 		5 / 12 ILE A 135
GLY A 129
ALA A 134
ALA A 118
PHE A 148
 None
 1.11A 2yvlA-4j4wA:
undetectable		 2yvlA-4j4wA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_B_SAMB602_0
(HYPOTHETICAL PROTEIN)		 4j4w NUCLEOCAPSID
(Punta
Toro
phlebovirus) 		5 / 12 ILE A 135
GLY A 129
ALA A 134
ALA A 118
PHE A 148
 None
 1.10A 2yvlB-4j4wA:
undetectable		 2yvlB-4j4wA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_C_SAMC604_0
(HYPOTHETICAL PROTEIN)		 4j4w NUCLEOCAPSID
(Punta
Toro
phlebovirus) 		5 / 12 ILE A 135
GLY A 129
ALA A 134
ALA A 118
PHE A 148
 None
 1.15A 2yvlC-4j4wA:
undetectable		 2yvlC-4j4wA:
22.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4J4V_A_SVRA301_1
(NUCLEOCAPSID PROTEIN)		 4j4w NUCLEOCAPSID
(Punta
Toro
phlebovirus) 		5 / 11 GLY A  64
ASN A  65
PRO A 126
PHE A 175
ILE A 179
 None
 0.73A 4j4vA-4j4wA:
31.8		 4j4vA-4j4wA:
37.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4J4V_B_SVRB301_1
(NUCLEOCAPSID PROTEIN)		 4j4w NUCLEOCAPSID
(Punta
Toro
phlebovirus) 		5 / 10 GLY A  64
ASN A  65
LYS A  66
PRO A 126
PHE A 175
 None
 0.81A 4j4vB-4j4wA:
20.4		 4j4vB-4j4wA:
37.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4J4V_C_SVRC301_1
(NUCLEOCAPSID PROTEIN)		 4j4w NUCLEOCAPSID
(Punta
Toro
phlebovirus) 		6 / 8 GLY A  64
ASN A  65
LYS A  66
PRO A 126
PHE A 175
ILE A 179
 None
 0.89A 4j4vC-4j4wA:
31.8		 4j4vC-4j4wA:
37.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4J4V_D_SVRD301_1
(NUCLEOCAPSID PROTEIN)		 4j4w NUCLEOCAPSID
(Punta
Toro
phlebovirus) 		5 / 11 GLY A  64
ASN A  65
PRO A 126
PHE A 175
ILE A 179
 None
 0.75A 4j4vD-4j4wA:
31.5
4j4vE-4j4wA:
31.2		 4j4vD-4j4wA:
37.85
4j4vE-4j4wA:
37.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCG_A_08YA602_1
(CYTOCHROME P450 3A4)		 4j4w NUCLEOCAPSID
(Punta
Toro
phlebovirus) 		5 / 12 PHE A 139
ILE A 203
ALA A 111
THR A 114
ALA A 142
 None
 1.29A 5vcgA-4j4wA:
undetectable		 5vcgA-4j4wA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AK3_B_P2EB1201_1
(PROSTAGLANDIN E2
RECEPTOR EP3
SUBTYPE,SOLUBLE
CYTOCHROME B562)		 4j4w NUCLEOCAPSID
(Punta
Toro
phlebovirus) 		4 / 5 PRO A 229
VAL A 233
GLY A 112
VAL A 152
 None
 0.83A 6ak3B-4j4wA:
undetectable		 6ak3B-4j4wA:
15.45