SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4j5a'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4j5a PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
F, MITOCHONDRIAL
(Homo
sapiens) 		5 / 9 SER X 152
GLY X  92
HIS X 112
ALA X 106
ILE X 200
 None
 1.39A 1c9sJ-4j5aX:
undetectable
1c9sK-4j5aX:
undetectable		 1c9sJ-4j5aX:
23.08
1c9sK-4j5aX:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4004_1
(SERUM ALBUMIN)		 4j5a PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
F, MITOCHONDRIAL
(Homo
sapiens) 		4 / 4 VAL X 139
PHE X 155
SER X 141
VAL X 170
 None
67Z  X 301 (-3.8A)
None
None
 1.34A 1e7cA-4j5aX:
undetectable		 1e7cA-4j5aX:
13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4j5a PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
F, MITOCHONDRIAL
(Homo
sapiens) 		5 / 10 SER X 152
GLY X  92
HIS X 112
ALA X 106
ILE X 200
 None
 1.40A 1gtfH-4j5aX:
undetectable
1gtfI-4j5aX:
undetectable		 1gtfH-4j5aX:
23.08
1gtfI-4j5aX:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		 4j5a PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
F, MITOCHONDRIAL
(Homo
sapiens) 		3 / 3 TYR X  90
GLY X  92
PHE X 109
 None
 0.68A 2m2pB-4j5aX:
undetectable		 2m2pB-4j5aX:
11.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4j5a PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
F, MITOCHONDRIAL
(Homo
sapiens) 		5 / 10 SER X 152
GLY X  92
HIS X 112
ALA X 106
ILE X 200
 None
 1.38A 5eeuJ-4j5aX:
undetectable
5eeuK-4j5aX:
undetectable		 5eeuJ-4j5aX:
23.08
5eeuK-4j5aX:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4j5a PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
F, MITOCHONDRIAL
(Homo
sapiens) 		5 / 10 GLY X  92
HIS X 112
ALA X 106
ILE X 200
SER X 152
 None
 1.44A 5eeuT-4j5aX:
undetectable
5eeuU-4j5aX:
undetectable		 5eeuT-4j5aX:
23.08
5eeuU-4j5aX:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4j5a PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
F, MITOCHONDRIAL
(Homo
sapiens) 		5 / 9 SER X 152
GLY X  92
HIS X 112
ALA X 106
ILE X 200
 None
 1.39A 5eevH-4j5aX:
undetectable
5eevI-4j5aX:
undetectable		 5eevH-4j5aX:
23.08
5eevI-4j5aX:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4j5a PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
F, MITOCHONDRIAL
(Homo
sapiens) 		5 / 10 SER X 152
GLY X  92
HIS X 112
ALA X 106
ILE X 200
 None
 1.38A 5eevJ-4j5aX:
undetectable
5eevK-4j5aX:
undetectable		 5eevJ-4j5aX:
23.08
5eevK-4j5aX:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4j5a PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
F, MITOCHONDRIAL
(Homo
sapiens) 		5 / 10 GLY X  92
HIS X 112
ALA X 106
ILE X 200
SER X 152
 None
 1.44A 5eevT-4j5aX:
undetectable
5eevU-4j5aX:
undetectable		 5eevT-4j5aX:
23.08
5eevU-4j5aX:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4j5a PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
F, MITOCHONDRIAL
(Homo
sapiens) 		5 / 10 SER X 152
GLY X  92
HIS X 112
ALA X 106
ILE X 200
 None
 1.40A 5eewH-4j5aX:
undetectable
5eewI-4j5aX:
undetectable		 5eewH-4j5aX:
23.08
5eewI-4j5aX:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4j5a PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
F, MITOCHONDRIAL
(Homo
sapiens) 		5 / 10 SER X 152
GLY X  92
HIS X 112
ALA X 106
ILE X 200
 None
 1.38A 5eewJ-4j5aX:
undetectable
5eewK-4j5aX:
undetectable		 5eewJ-4j5aX:
23.08
5eewK-4j5aX:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4j5a PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
F, MITOCHONDRIAL
(Homo
sapiens) 		5 / 10 GLY X  92
HIS X 112
ALA X 106
ILE X 200
SER X 152
 None
 1.44A 5eewT-4j5aX:
undetectable
5eewU-4j5aX:
undetectable		 5eewT-4j5aX:
23.08
5eewU-4j5aX:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4j5a PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
F, MITOCHONDRIAL
(Homo
sapiens) 		5 / 10 SER X 152
GLY X  92
HIS X 112
ALA X 106
ILE X 200
 None
 1.40A 5eexH-4j5aX:
undetectable
5eexI-4j5aX:
undetectable		 5eexH-4j5aX:
23.08
5eexI-4j5aX:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4j5a PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
F, MITOCHONDRIAL
(Homo
sapiens) 		5 / 10 SER X 152
GLY X  92
HIS X 112
ALA X 106
ILE X 200
 None
 1.38A 5eexJ-4j5aX:
undetectable
5eexK-4j5aX:
undetectable		 5eexJ-4j5aX:
23.08
5eexK-4j5aX:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4j5a PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
F, MITOCHONDRIAL
(Homo
sapiens) 		5 / 10 GLY X  92
HIS X 112
ALA X 106
ILE X 200
SER X 152
 None
 1.44A 5eexT-4j5aX:
undetectable
5eexU-4j5aX:
undetectable		 5eexT-4j5aX:
23.08
5eexU-4j5aX:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4j5a PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
F, MITOCHONDRIAL
(Homo
sapiens) 		5 / 9 SER X 152
GLY X  92
HIS X 112
ALA X 106
ILE X 200
 None
 1.40A 5eeyH-4j5aX:
undetectable
5eeyI-4j5aX:
undetectable		 5eeyH-4j5aX:
23.08
5eeyI-4j5aX:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4j5a PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
F, MITOCHONDRIAL
(Homo
sapiens) 		5 / 10 SER X 152
GLY X  92
HIS X 112
ALA X 106
ILE X 200
 None
 1.38A 5eeyJ-4j5aX:
undetectable
5eeyK-4j5aX:
undetectable		 5eeyJ-4j5aX:
23.08
5eeyK-4j5aX:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4j5a PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
F, MITOCHONDRIAL
(Homo
sapiens) 		5 / 10 GLY X  92
HIS X 112
ALA X 106
ILE X 200
SER X 152
 None
 1.44A 5eeyT-4j5aX:
undetectable
5eeyU-4j5aX:
undetectable		 5eeyT-4j5aX:
23.08
5eeyU-4j5aX:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4j5a PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
F, MITOCHONDRIAL
(Homo
sapiens) 		5 / 9 SER X 152
GLY X  92
HIS X 112
ALA X 106
ILE X 200
 None
 1.40A 5eezH-4j5aX:
undetectable
5eezI-4j5aX:
undetectable		 5eezH-4j5aX:
23.08
5eezI-4j5aX:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4j5a PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
F, MITOCHONDRIAL
(Homo
sapiens) 		5 / 9 SER X 152
GLY X  92
HIS X 112
ALA X 106
ILE X 200
 None
 1.38A 5eezJ-4j5aX:
undetectable
5eezK-4j5aX:
undetectable		 5eezJ-4j5aX:
23.08
5eezK-4j5aX:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4j5a PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
F, MITOCHONDRIAL
(Homo
sapiens) 		5 / 10 GLY X  92
HIS X 112
ALA X 106
ILE X 200
SER X 152
 None
 1.45A 5eezT-4j5aX:
undetectable
5eezU-4j5aX:
undetectable		 5eezT-4j5aX:
23.08
5eezU-4j5aX:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4j5a PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
F, MITOCHONDRIAL
(Homo
sapiens) 		5 / 9 SER X 152
GLY X  92
HIS X 112
ALA X 106
ILE X 200
 None
 1.40A 5ef0H-4j5aX:
undetectable
5ef0I-4j5aX:
undetectable		 5ef0H-4j5aX:
23.08
5ef0I-4j5aX:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4j5a PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
F, MITOCHONDRIAL
(Homo
sapiens) 		5 / 9 SER X 152
GLY X  92
HIS X 112
ALA X 106
ILE X 200
 None
 1.38A 5ef0J-4j5aX:
undetectable
5ef0K-4j5aX:
undetectable		 5ef0J-4j5aX:
23.08
5ef0K-4j5aX:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4j5a PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
F, MITOCHONDRIAL
(Homo
sapiens) 		5 / 10 GLY X  92
HIS X 112
ALA X 106
ILE X 200
SER X 152
 None
 1.45A 5ef0T-4j5aX:
undetectable
5ef0U-4j5aX:
undetectable		 5ef0T-4j5aX:
23.08
5ef0U-4j5aX:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4j5a PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
F, MITOCHONDRIAL
(Homo
sapiens) 		5 / 9 SER X 152
GLY X  92
HIS X 112
ALA X 106
ILE X 200
 None
 1.40A 5ef1B-4j5aX:
undetectable
5ef1C-4j5aX:
undetectable		 5ef1B-4j5aX:
23.08
5ef1C-4j5aX:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4j5a PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
F, MITOCHONDRIAL
(Homo
sapiens) 		5 / 9 SER X 152
GLY X  92
HIS X 112
ALA X 106
ILE X 200
 None
 1.40A 5ef1H-4j5aX:
undetectable
5ef1I-4j5aX:
undetectable		 5ef1H-4j5aX:
23.08
5ef1I-4j5aX:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4j5a PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
F, MITOCHONDRIAL
(Homo
sapiens) 		5 / 9 SER X 152
GLY X  92
HIS X 112
ALA X 106
ILE X 200
 None
 1.38A 5ef1J-4j5aX:
undetectable
5ef1K-4j5aX:
undetectable		 5ef1J-4j5aX:
23.08
5ef1K-4j5aX:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4j5a PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
F, MITOCHONDRIAL
(Homo
sapiens) 		5 / 10 GLY X  92
HIS X 112
ALA X 106
ILE X 200
SER X 152
 None
 1.45A 5ef1T-4j5aX:
undetectable
5ef1U-4j5aX:
undetectable		 5ef1T-4j5aX:
23.08
5ef1U-4j5aX:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4j5a PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
F, MITOCHONDRIAL
(Homo
sapiens) 		5 / 9 SER X 152
GLY X  92
HIS X 112
ALA X 106
ILE X 200
 None
 1.40A 5ef2B-4j5aX:
undetectable
5ef2C-4j5aX:
undetectable		 5ef2B-4j5aX:
23.08
5ef2C-4j5aX:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4j5a PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
F, MITOCHONDRIAL
(Homo
sapiens) 		5 / 9 SER X 152
GLY X  92
HIS X 112
ALA X 106
ILE X 200
 None
 1.38A 5ef2J-4j5aX:
undetectable
5ef2K-4j5aX:
undetectable		 5ef2J-4j5aX:
23.08
5ef2K-4j5aX:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4j5a PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
F, MITOCHONDRIAL
(Homo
sapiens) 		5 / 10 GLY X  92
HIS X 112
ALA X 106
ILE X 200
SER X 152
 None
 1.45A 5ef2T-4j5aX:
undetectable
5ef2U-4j5aX:
undetectable		 5ef2T-4j5aX:
23.08
5ef2U-4j5aX:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4j5a PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
F, MITOCHONDRIAL
(Homo
sapiens) 		5 / 9 SER X 152
GLY X  92
HIS X 112
ALA X 106
ILE X 200
 None
 1.40A 5ef3B-4j5aX:
undetectable
5ef3C-4j5aX:
undetectable		 5ef3B-4j5aX:
23.08
5ef3C-4j5aX:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4j5a PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
F, MITOCHONDRIAL
(Homo
sapiens) 		5 / 9 SER X 152
GLY X  92
HIS X 112
ALA X 106
ILE X 200
 None
 1.40A 5ef3H-4j5aX:
undetectable
5ef3I-4j5aX:
undetectable		 5ef3H-4j5aX:
23.08
5ef3I-4j5aX:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4j5a PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
F, MITOCHONDRIAL
(Homo
sapiens) 		5 / 9 SER X 152
GLY X  92
HIS X 112
ALA X 106
ILE X 200
 None
 1.38A 5ef3J-4j5aX:
undetectable
5ef3K-4j5aX:
undetectable		 5ef3J-4j5aX:
23.08
5ef3K-4j5aX:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4j5a PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
F, MITOCHONDRIAL
(Homo
sapiens) 		5 / 10 GLY X  92
HIS X 112
ALA X 106
ILE X 200
SER X 152
 None
 1.38A 5ef3A-4j5aX:
undetectable
5ef3K-4j5aX:
undetectable		 5ef3A-4j5aX:
23.08
5ef3K-4j5aX:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4j5a PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
F, MITOCHONDRIAL
(Homo
sapiens) 		5 / 10 GLY X  92
HIS X 112
ALA X 106
ILE X 200
SER X 152
 None
 1.45A 5ef3T-4j5aX:
undetectable
5ef3U-4j5aX:
undetectable		 5ef3T-4j5aX:
23.08
5ef3U-4j5aX:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FA8_A_SAMA301_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE,
PUTATIVE)		 4j5a PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
F, MITOCHONDRIAL
(Homo
sapiens) 		5 / 12 GLY X 151
ILE X 120
ASN X 144
PHE X  78
LEU X 140
 67Z  X 301 (-3.8A)
None
None
None
None
 1.09A 5fa8A-4j5aX:
undetectable		 5fa8A-4j5aX:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGZ_A_SPRA404_2
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 4j5a PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
F, MITOCHONDRIAL
(Homo
sapiens) 		5 / 9 LEU X 140
ARG X  79
GLU X 128
PHE X 171
VAL X 169
 None
 1.50A 5igzA-4j5aX:
undetectable		 5igzA-4j5aX:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZNC_A_QI9A301_0
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4j5a PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
F, MITOCHONDRIAL
(Homo
sapiens) 		5 / 9 VAL X 180
SER X 186
GLY X 188
VAL X  98
GLU X 185
 None
 1.30A 5zncA-4j5aX:
undetectable		 5zncA-4j5aX:
24.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CJK_C_ACTC301_0
(IMMUNOGLOBULIN FAB
LIGHT CHAIN)		 4j5a PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
F, MITOCHONDRIAL
(Homo
sapiens) 		4 / 4 VAL X 180
GLY X  60
ASP X  51
ASP X  53
 None
 1.41A 6cjkC-4j5aX:
undetectable		 6cjkC-4j5aX:
19.25