SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4j5q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		 4j5q O-ACETYL-ADP-RIBOSE
DEACETYLASE 1
(Homo
sapiens) 		5 / 11 SER A  65
ALA A  69
THR A  83
ALA A  45
LEU A  58
 None
 1.05A 1jinA-4j5qA:
undetectable		 1jinA-4j5qA:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KI7_B_ID2B2_0
(THYMIDINE KINASE)		 4j5q O-ACETYL-ADP-RIBOSE
DEACETYLASE 1
(Homo
sapiens) 		5 / 12 ILE A 136
ILE A 147
MET A 117
ARG A 119
TYR A  16
 None
 1.22A 1ki7B-4j5qA:
undetectable		 1ki7B-4j5qA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KI7_B_ID2B2_0
(THYMIDINE KINASE)		 4j5q O-ACETYL-ADP-RIBOSE
DEACETYLASE 1
(Homo
sapiens) 		5 / 12 ILE A 136
ILE A 147
MET A 117
TYR A  16
GLU A 137
 None
 1.34A 1ki7B-4j5qA:
undetectable		 1ki7B-4j5qA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RTS_A_D16A309_1
(THYMIDYLATE SYNTHASE)		 4j5q O-ACETYL-ADP-RIBOSE
DEACETYLASE 1
(Homo
sapiens) 		4 / 8 PHE A  48
ILE A  78
LEU A  58
GLY A  54
 None
 0.61A 1rtsA-4j5qA:
undetectable		 1rtsA-4j5qA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_A_CHDA151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 4j5q O-ACETYL-ADP-RIBOSE
DEACETYLASE 1
(Homo
sapiens) 		5 / 10 ILE A 120
VAL A  68
GLY A  66
VAL A 139
LEU A 127
 None
 1.26A 3em0A-4j5qA:
undetectable		 3em0A-4j5qA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H3A_B_D16B401_1
(ORF70)		 4j5q O-ACETYL-ADP-RIBOSE
DEACETYLASE 1
(Homo
sapiens) 		4 / 7 PHE A  48
ILE A  78
LEU A  58
GLY A  54
 None
 0.65A 5h3aB-4j5qA:
undetectable		 5h3aB-4j5qA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 4j5q O-ACETYL-ADP-RIBOSE
DEACETYLASE 1
(Homo
sapiens) 		4 / 7 PHE A  48
ILE A  78
LEU A  58
GLY A  54
 None
 0.63A 5x5qC-4j5qA:
undetectable		 5x5qC-4j5qA:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 4j5q O-ACETYL-ADP-RIBOSE
DEACETYLASE 1
(Homo
sapiens) 		4 / 8 PHE A  48
ILE A  78
LEU A  58
GLY A  54
 None
 0.62A 5x5qD-4j5qA:
undetectable		 5x5qD-4j5qA:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_E_D16E402_1
(THYMIDYLATE SYNTHASE)		 4j5q O-ACETYL-ADP-RIBOSE
DEACETYLASE 1
(Homo
sapiens) 		4 / 6 PHE A  48
ILE A  78
LEU A  58
GLY A  54
 None
 0.64A 5x5qE-4j5qA:
undetectable		 5x5qE-4j5qA:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_F_D16F402_1
(THYMIDYLATE SYNTHASE)		 4j5q O-ACETYL-ADP-RIBOSE
DEACETYLASE 1
(Homo
sapiens) 		4 / 8 PHE A  48
ILE A  78
LEU A  58
GLY A  54
 None
 0.61A 5x5qF-4j5qA:
undetectable		 5x5qF-4j5qA:
17.83