SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4j5u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1DFO_A_FFOA1002_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	7 / 12	GLY A 124 SER A 176 ALA A 177 ASN A 346 SER A 354 PRO A 355 ARG A 362	None	1.07A	1dfoA-4j5uA: 59.7	1dfoA-4j5uA: 56.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1DFO_A_FFOA1002_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	7 / 12	GLY A 124 SER A 176 ALA A 177 SER A 354 PRO A 355 PHE A 356 ARG A 362	None	0.95A	1dfoA-4j5uA: 59.7	1dfoA-4j5uA: 56.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1DFO_A_FFOA1002_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	7 / 12	LEU A 121 GLY A 124 HIS A 126 LEU A 127 SER A 176 ALA A 177 ARG A 362	None None LLP A 230 ( 3.5A) None None None None	0.97A	1dfoA-4j5uA: 59.7	1dfoA-4j5uA: 56.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1DFO_A_FFOA1002_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	7 / 12	LEU A 121 GLY A 124 SER A 176 ALA A 177 SER A 354 PHE A 356 ARG A 362	None	1.12A	1dfoA-4j5uA: 59.7	1dfoA-4j5uA: 56.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1DFO_A_FFOA1002_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	4 / 5	GLU A 57 TYR A 65 PHE A 256 PRO A 257	None	0.40A	1dfoB-4j5uA: 60.9	1dfoB-4j5uA: 56.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1DFO_B_FFOB2002_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	4 / 5	GLU A 57 TYR A 65 PHE A 256 PRO A 257	None	0.40A	1dfoA-4j5uA: 59.7	1dfoA-4j5uA: 56.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1DFO_B_FFOB2002_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	7 / 12	GLY A 124 SER A 176 ALA A 177 ASN A 346 SER A 354 PRO A 355 ARG A 362	None	1.07A	1dfoB-4j5uA: 60.9	1dfoB-4j5uA: 56.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1DFO_B_FFOB2002_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	7 / 12	GLY A 124 SER A 176 ALA A 177 SER A 354 PRO A 355 PHE A 356 ARG A 362	None	0.96A	1dfoB-4j5uA: 60.9	1dfoB-4j5uA: 56.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1DFO_B_FFOB2002_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	7 / 12	LEU A 121 GLY A 124 HIS A 126 LEU A 127 SER A 176 ALA A 177 ARG A 362	None None LLP A 230 ( 3.5A) None None None None	0.97A	1dfoB-4j5uA: 60.9	1dfoB-4j5uA: 56.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1DFO_B_FFOB2002_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	7 / 12	LEU A 121 GLY A 124 SER A 176 ALA A 177 SER A 354 PHE A 356 ARG A 362	None	1.12A	1dfoB-4j5uA: 60.9	1dfoB-4j5uA: 56.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1DFO_C_FFOC3002_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	7 / 12	GLY A 124 SER A 176 ALA A 177 ASN A 346 SER A 354 PRO A 355 ARG A 362	None	1.07A	1dfoC-4j5uA: 60.9	1dfoC-4j5uA: 56.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1DFO_C_FFOC3002_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	7 / 12	GLY A 124 SER A 176 ALA A 177 SER A 354 PRO A 355 PHE A 356 ARG A 362	None	0.95A	1dfoC-4j5uA: 60.9	1dfoC-4j5uA: 56.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1DFO_C_FFOC3002_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	7 / 12	LEU A 121 GLY A 124 HIS A 126 LEU A 127 SER A 176 ALA A 177 ARG A 362	None None LLP A 230 ( 3.5A) None None None None	0.96A	1dfoC-4j5uA: 60.9	1dfoC-4j5uA: 56.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1DFO_C_FFOC3002_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	7 / 12	LEU A 121 GLY A 124 SER A 176 ALA A 177 SER A 354 PHE A 356 ARG A 362	None	1.12A	1dfoC-4j5uA: 60.9	1dfoC-4j5uA: 56.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1DFO_C_FFOC3002_2 (SERINE HYDROXYMETHYLTRANSFE RASE)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	4 / 5	GLU A 57 TYR A 65 PHE A 256 PRO A 257	None	0.40A	1dfoD-4j5uA: 59.7	1dfoD-4j5uA: 56.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1DFO_D_FFOD4002_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	4 / 5	GLU A 57 TYR A 65 PHE A 256 PRO A 257	None	0.40A	1dfoC-4j5uA: 60.9	1dfoC-4j5uA: 56.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1DFO_D_FFOD4002_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	7 / 12	GLY A 124 SER A 176 ALA A 177 ASN A 346 SER A 354 PRO A 355 ARG A 362	None	1.07A	1dfoD-4j5uA: 59.7	1dfoD-4j5uA: 56.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1DFO_D_FFOD4002_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	7 / 12	GLY A 124 SER A 176 ALA A 177 SER A 354 PRO A 355 PHE A 356 ARG A 362	None	0.95A	1dfoD-4j5uA: 59.7	1dfoD-4j5uA: 56.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1DFO_D_FFOD4002_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	7 / 12	LEU A 121 GLY A 124 HIS A 126 LEU A 127 SER A 176 ALA A 177 ARG A 362	None None LLP A 230 ( 3.5A) None None None None	0.97A	1dfoD-4j5uA: 59.7	1dfoD-4j5uA: 56.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1DFO_D_FFOD4002_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	7 / 12	LEU A 121 GLY A 124 SER A 176 ALA A 177 SER A 354 PHE A 356 ARG A 362	None	1.12A	1dfoD-4j5uA: 59.7	1dfoD-4j5uA: 56.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1EQB_A_FFOA1293_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	6 / 12	GLY A 124 SER A 176 ALA A 177 ASN A 346 PRO A 355 ARG A 362	None	0.99A	1eqbA-4j5uA: 59.6	1eqbA-4j5uA: 55.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1EQB_A_FFOA1293_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	6 / 12	GLY A 124 SER A 176 ALA A 177 ASN A 346 SER A 354 PRO A 355	None	1.03A	1eqbA-4j5uA: 59.6	1eqbA-4j5uA: 55.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1EQB_A_FFOA1293_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	6 / 12	GLY A 124 SER A 176 ALA A 177 PRO A 355 PHE A 356 ARG A 362	None	0.88A	1eqbA-4j5uA: 59.6	1eqbA-4j5uA: 55.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1EQB_A_FFOA1293_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	6 / 12	GLY A 124 SER A 176 ALA A 177 SER A 354 PRO A 355 PHE A 356	None	0.88A	1eqbA-4j5uA: 59.6	1eqbA-4j5uA: 55.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1EQB_A_FFOA1293_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	7 / 12	LEU A 121 GLY A 124 HIS A 126 LEU A 127 SER A 176 ALA A 177 ARG A 362	None None LLP A 230 ( 3.5A) None None None None	0.99A	1eqbA-4j5uA: 59.6	1eqbA-4j5uA: 55.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1EQB_A_FFOA1293_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	6 / 12	LEU A 121 GLY A 124 SER A 176 ALA A 177 PHE A 356 ARG A 362	None	1.04A	1eqbA-4j5uA: 59.6	1eqbA-4j5uA: 55.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1EQB_A_FFOA1293_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	6 / 12	LEU A 121 GLY A 124 SER A 176 ALA A 177 SER A 354 PHE A 356	None	1.05A	1eqbA-4j5uA: 59.6	1eqbA-4j5uA: 55.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1EQB_A_GLYA1292_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	4 / 8	SER A 35 HIS A 126 SER A 176 HIS A 204	LLP A 230 ( 4.9A) LLP A 230 ( 3.5A) None LLP A 230 ( 4.1A)	0.68A	1eqbA-4j5uA: 59.6 1eqbB-4j5uA: 60.9	1eqbA-4j5uA: 55.79 1eqbB-4j5uA: 55.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1EQB_B_FFOB2293_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	7 / 12	GLY A 124 SER A 176 ALA A 177 ASN A 346 SER A 354 PRO A 355 ARG A 362	None	1.08A	1eqbB-4j5uA: 60.9	1eqbB-4j5uA: 55.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1EQB_B_FFOB2293_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	7 / 12	GLY A 124 SER A 176 ALA A 177 SER A 354 PRO A 355 PHE A 356 ARG A 362	None	0.96A	1eqbB-4j5uA: 60.9	1eqbB-4j5uA: 55.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1EQB_B_FFOB2293_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	7 / 12	LEU A 121 GLY A 124 HIS A 126 LEU A 127 SER A 176 ALA A 177 ARG A 362	None None LLP A 230 ( 3.5A) None None None None	0.99A	1eqbB-4j5uA: 60.9	1eqbB-4j5uA: 55.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1EQB_B_FFOB2293_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	7 / 12	LEU A 121 GLY A 124 SER A 176 ALA A 177 SER A 354 PHE A 356 ARG A 362	None	1.10A	1eqbB-4j5uA: 60.9	1eqbB-4j5uA: 55.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1EQB_B_FFOB2293_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	5 / 12	LEU A 121 SER A 176 ALA A 177 ASN A 346 ARG A 362	None	1.16A	1eqbB-4j5uA: 60.9	1eqbB-4j5uA: 55.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1EQB_B_GLYB2292_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	4 / 8	SER A 35 HIS A 126 SER A 176 HIS A 204	LLP A 230 ( 4.9A) LLP A 230 ( 3.5A) None LLP A 230 ( 4.1A)	0.69A	1eqbA-4j5uA: 59.6 1eqbB-4j5uA: 60.9	1eqbA-4j5uA: 55.79 1eqbB-4j5uA: 55.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1EQB_C_FFOC3293_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	6 / 12	GLY A 124 SER A 176 ALA A 177 ASN A 346 PRO A 355 ARG A 362	None	0.99A	1eqbC-4j5uA: 60.8	1eqbC-4j5uA: 55.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1EQB_C_FFOC3293_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	6 / 12	GLY A 124 SER A 176 ALA A 177 ASN A 346 SER A 354 PRO A 355	None	1.03A	1eqbC-4j5uA: 60.8	1eqbC-4j5uA: 55.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1EQB_C_FFOC3293_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	6 / 12	GLY A 124 SER A 176 ALA A 177 PRO A 355 PHE A 356 ARG A 362	None	0.88A	1eqbC-4j5uA: 60.8	1eqbC-4j5uA: 55.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1EQB_C_FFOC3293_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	6 / 12	GLY A 124 SER A 176 ALA A 177 SER A 354 PRO A 355 PHE A 356	None	0.89A	1eqbC-4j5uA: 60.8	1eqbC-4j5uA: 55.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1EQB_C_FFOC3293_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	7 / 12	LEU A 121 GLY A 124 HIS A 126 LEU A 127 SER A 176 ALA A 177 ARG A 362	None None LLP A 230 ( 3.5A) None None None None	0.99A	1eqbC-4j5uA: 60.8	1eqbC-4j5uA: 55.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1EQB_C_FFOC3293_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	6 / 12	LEU A 121 GLY A 124 SER A 176 ALA A 177 PHE A 356 ARG A 362	None	1.05A	1eqbC-4j5uA: 60.8	1eqbC-4j5uA: 55.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1EQB_C_FFOC3293_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	6 / 12	LEU A 121 GLY A 124 SER A 176 ALA A 177 SER A 354 PHE A 356	None	1.06A	1eqbC-4j5uA: 60.8	1eqbC-4j5uA: 55.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1EQB_C_GLYC3292_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	4 / 8	SER A 35 HIS A 126 SER A 176 HIS A 204	LLP A 230 ( 4.9A) LLP A 230 ( 3.5A) None LLP A 230 ( 4.1A)	0.69A	1eqbC-4j5uA: 60.8 1eqbD-4j5uA: 60.8	1eqbC-4j5uA: 55.79 1eqbD-4j5uA: 55.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1EQB_D_FFOD4293_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	7 / 12	GLY A 124 SER A 176 ALA A 177 ASN A 346 SER A 354 PRO A 355 ARG A 362	None	1.08A	1eqbD-4j5uA: 60.8	1eqbD-4j5uA: 55.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1EQB_D_FFOD4293_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	7 / 12	GLY A 124 SER A 176 ALA A 177 SER A 354 PRO A 355 PHE A 356 ARG A 362	None	0.96A	1eqbD-4j5uA: 60.8	1eqbD-4j5uA: 55.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1EQB_D_FFOD4293_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	7 / 12	LEU A 121 GLY A 124 HIS A 126 LEU A 127 SER A 176 ALA A 177 ARG A 362	None None LLP A 230 ( 3.5A) None None None None	0.99A	1eqbD-4j5uA: 60.8	1eqbD-4j5uA: 55.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1EQB_D_FFOD4293_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	7 / 12	LEU A 121 GLY A 124 SER A 176 ALA A 177 SER A 354 PHE A 356 ARG A 362	None	1.10A	1eqbD-4j5uA: 60.8	1eqbD-4j5uA: 55.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1EQB_D_GLYD4292_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	4 / 8	SER A 35 HIS A 126 SER A 176 HIS A 204	LLP A 230 ( 4.9A) LLP A 230 ( 3.5A) None LLP A 230 ( 4.1A)	0.69A	1eqbC-4j5uA: 60.8 1eqbD-4j5uA: 60.8	1eqbC-4j5uA: 55.79 1eqbD-4j5uA: 55.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EQG_A_IBPA701_1 (PROSTAGLANDIN H2 SYNTHASE-1)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	5 / 9	TYR A 306 ILE A 327 ALA A 332 SER A 335 LEU A 336	None	1.13A	1eqgA-4j5uA: undetectable	1eqgA-4j5uA: 22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EQG_B_IBPB1701_1 (PROSTAGLANDIN H2 SYNTHASE-1)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	5 / 11	TYR A 306 ILE A 327 ALA A 332 SER A 335 LEU A 336	None	1.14A	1eqgB-4j5uA: undetectable	1eqgB-4j5uA: 22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1N49_D_RITD401_1 (PROTEASE)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	5 / 11	ALA A 173 ASP A 201 VAL A 224 ILE A 202 PRO A 219	None LLP A 230 ( 2.9A) None None None	0.95A	1n49C-4j5uA: undetectable	1n49C-4j5uA: 14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Q23_C_FUAC701_1 (CHLORAMPHENICOL ACETYLTRANSFERASE)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	4 / 4	ALA A 46 VAL A 273 ALA A 270 HIS A 266	None	1.10A	1q23A-4j5uA: undetectable	1q23A-4j5uA: 19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1TDN_A_LEUA487_0 (L-AMINO ACID OXIDASE)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	4 / 7	ASN A 134 HIS A 126 TYR A 106 ILE A 172	None LLP A 230 ( 3.5A) None None	1.37A	1tdnA-4j5uA: undetectable	1tdnA-4j5uA: 25.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1UKB_A_BEZA1300_0 (2-HYDROXY-6-OXO-7-ME THYLOCTA-2,4-DIENOAT E HYDROLASE)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	5 / 11	GLY A 238 SER A 97 ALA A 101 ALA A 104 LEU A 259	None LLP A 230 ( 3.4A) None None None	1.16A	1ukbA-4j5uA: undetectable	1ukbA-4j5uA: 22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2CEO_B_T44B1395_1 (THYROXINE-BINDING GLOBULIN)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	5 / 10	ALA A 339 LEU A 301 LEU A 363 SER A 335 LEU A 336	None	1.39A	2ceoB-4j5uA: undetectable	2ceoB-4j5uA: 22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Q5K_A_AB1A201_2 (PROTEASE)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	5 / 12	ALA A 173 ASP A 201 VAL A 224 ILE A 202 PRO A 219	None LLP A 230 ( 2.9A) None None None	0.81A	2q5kB-4j5uA: undetectable	2q5kB-4j5uA: 13.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2VMY_A_FFOA505_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	4 / 6	GLU A 57 TYR A 65 PHE A 256 PRO A 257	None	0.40A	2vmyA-4j5uA: 60.2	2vmyA-4j5uA: 57.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2VMY_A_FFOA505_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	5 / 12	GLY A 124 ALA A 177 ASN A 346 PRO A 355 ARG A 362	None	0.86A	2vmyB-4j5uA: 60.1	2vmyB-4j5uA: 57.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2VMY_A_FFOA505_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	5 / 12	GLY A 124 ALA A 177 ASN A 346 SER A 354 PRO A 355	None	1.02A	2vmyB-4j5uA: 60.1	2vmyB-4j5uA: 57.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2VMY_A_FFOA505_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	6 / 12	LEU A 121 GLY A 124 HIS A 126 LEU A 127 ALA A 177 ARG A 362	None None LLP A 230 ( 3.5A) None None None	0.97A	2vmyB-4j5uA: 60.1	2vmyB-4j5uA: 57.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2VMY_A_FFOA505_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	5 / 12	LEU A 121 HIS A 126 LEU A 127 SER A 176 ARG A 362	None LLP A 230 ( 3.5A) None None None	1.02A	2vmyB-4j5uA: 60.1	2vmyB-4j5uA: 57.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2VMY_B_FFOB505_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	5 / 12	GLY A 124 ALA A 177 SER A 354 PRO A 355 ARG A 362	None	1.01A	2vmyA-4j5uA: 60.2	2vmyA-4j5uA: 57.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2VMY_B_FFOB505_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	5 / 12	GLY A 124 SER A 176 ALA A 177 PRO A 355 ARG A 362	None	0.99A	2vmyA-4j5uA: 60.2	2vmyA-4j5uA: 57.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2VMY_B_FFOB505_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	7 / 12	LEU A 121 GLY A 124 HIS A 126 LEU A 127 SER A 176 ALA A 177 ARG A 362	None None LLP A 230 ( 3.5A) None None None None	0.99A	2vmyA-4j5uA: 60.2	2vmyA-4j5uA: 57.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2VMY_B_FFOB505_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	7 / 12	LEU A 121 HIS A 126 LEU A 127 SER A 176 ALA A 177 ASN A 344 ARG A 362	None LLP A 230 ( 3.5A) None None None None None	1.16A	2vmyA-4j5uA: 60.2	2vmyA-4j5uA: 57.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2VMY_B_GLYB502_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	4 / 8	SER A 35 HIS A 126 SER A 176 HIS A 204	LLP A 230 ( 4.9A) LLP A 230 ( 3.5A) None LLP A 230 ( 4.1A)	0.68A	2vmyA-4j5uA: 60.2 2vmyB-4j5uA: 60.1	2vmyA-4j5uA: 57.69 2vmyB-4j5uA: 57.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LUS_B_X8ZB1001_1 (ORGANIC HYDROPEROXIDE RESISTANCE PROTEIN)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	5 / 9	ASN A 92 ALA A 91 TYR A 59 PRO A 263 PRO A 95	None	1.40A	3lusA-4j5uA: 0.9 3lusB-4j5uA: 0.0	3lusA-4j5uA: 17.03 3lusB-4j5uA: 17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NUJ_B_478B401_1 (PROTEASE)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	5 / 10	ALA A 173 ASP A 201 VAL A 224 ILE A 202 PRO A 219	None LLP A 230 ( 2.9A) None None None	0.99A	3nujA-4j5uA: undetectable	3nujA-4j5uA: 14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OXX_A_DR7A100_2 (HIV-1 PROTEASE)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	5 / 11	ALA A 333 ASP A 337 ILE A 341 VAL A 320 ILE A 361	None	1.32A	3oxxB-4j5uA: undetectable	3oxxB-4j5uA: 14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3QF1_A_PZEA6951_1 (LACTOPEROXIDASE)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	3 / 3	HIS A 383 ARG A 304 GLU A 303	None	1.13A	3qf1A-4j5uA: undetectable	3qf1A-4j5uA: 20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SPK_A_TPVA100_1 (HIV-1 PROTEASE)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	5 / 11	ALA A 347 ASP A 351 ILE A 357 GLY A 329 ILE A 361	None	1.13A	3spkA-4j5uA: undetectable	3spkA-4j5uA: 13.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TL9_A_ROCA401_4 (PROTEASE)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	4 / 4	ASP A 307 ASP A 321 GLY A 326 THR A 358	None	1.33A	3tl9B-4j5uA: undetectable	3tl9B-4j5uA: 15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3V4T_H_ACTH503_0 (UDP-N-ACETYLGLUCOSAM INE 1-CARBOXYVINYLTRANSF ERASE)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	4 / 7	ALA A 347 ILE A 348 ARG A 362 GLY A 329	None	1.01A	3v4tH-4j5uA: undetectable	3v4tH-4j5uA: 24.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DM8_A_REAA501_1 (RETINOIC ACID RECEPTOR BETA)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	5 / 11	LEU A 336 ILE A 361 SER A 35 LEU A 301 ILE A 30	None None LLP A 230 ( 4.9A) None None	1.03A	4dm8A-4j5uA: undetectable	4dm8A-4j5uA: 21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DTZ_B_LDPB501_1 (CYTOCHROME P450 BM3 VARIANT 8C8)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	4 / 6	PHE A 86 ALA A 210 LEU A 232 THR A 231	None None None LLP A 230 ( 4.0A)	1.13A	4dtzB-4j5uA: undetectable	4dtzB-4j5uA: 25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4HTF_A_SAMA301_0 (S-ADENOSYLMETHIONINE -DEPENDENT METHYLTRANSFERASE)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	5 / 12	GLY A 340 LEU A 336 SER A 335 VAL A 409 VAL A 381	None	0.92A	4htfA-4j5uA: undetectable	4htfA-4j5uA: 23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4HTF_B_SAMB301_0 (S-ADENOSYLMETHIONINE -DEPENDENT METHYLTRANSFERASE)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	5 / 12	GLY A 340 LEU A 336 SER A 335 VAL A 409 VAL A 381	None	0.95A	4htfB-4j5uA: 3.3	4htfB-4j5uA: 23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PCL_B_SAMB301_0 (O-METHYLTRANSFERASE FAMILY PROTEIN)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	5 / 12	GLN A 94 LEU A 264 GLY A 238 ALA A 203 ASN A 102	None None None LLP A 230 ( 3.4A) LLP A 230 ( 4.5A)	1.27A	4pclB-4j5uA: 4.3	4pclB-4j5uA: 18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4RMJ_A_NCAA402_0 (NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-2)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	4 / 7	PHE A 198 LEU A 171 ILE A 182 ASP A 183	None	0.87A	4rmjA-4j5uA: 2.0	4rmjA-4j5uA: 22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4RZV_A_032A801_2 (SERINE/THREONINE-PRO TEIN KINASE B-RAF)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	4 / 5	ILE A 251 VAL A 105 PHE A 187 HIS A 249	None	1.20A	4rzvA-4j5uA: undetectable	4rzvA-4j5uA: 21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWD_A_377A402_1 (CYS-LOOP LIGAND-GATED ION CHANNEL)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	5 / 9	ALA A 269 ALA A 46 ALA A 42 SER A 40 ALA A 272	None	1.33A	4twdA-4j5uA: undetectable 4twdB-4j5uA: undetectable 4twdC-4j5uA: undetectable 4twdD-4j5uA: undetectable 4twdE-4j5uA: undetectable	4twdA-4j5uA: 23.15 4twdB-4j5uA: 23.15 4twdC-4j5uA: 23.15 4twdD-4j5uA: 23.15 4twdE-4j5uA: 23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UBE_A_2FAA401_2 (ADENOSINE KINASE)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	4 / 4	ALA A 272 VAL A 93 GLY A 238 THR A 228	None	1.14A	4ubeA-4j5uA: 4.3	4ubeA-4j5uA: 22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4X1F_A_3WFA501_1 (NUCLEAR RECEPTOR SUBFAMILY 1 GROUP I MEMBER 2)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	5 / 12	LEU A 322 LEU A 389 SER A 300 LEU A 363 ILE A 361	None	1.09A	4x1fA-4j5uA: undetectable	4x1fA-4j5uA: 21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4X1G_A_3WFA501_1 (NUCLEAR RECEPTOR SUBFAMILY 1 GROUP I MEMBER 2)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	5 / 12	LEU A 322 LEU A 389 SER A 300 LEU A 363 ILE A 361	None	1.09A	4x1gA-4j5uA: undetectable	4x1gA-4j5uA: 21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DPD_A_SAMA601_0 (PROTEIN LYSINE METHYLTRANSFERASE 1)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	5 / 12	GLY A 340 LEU A 336 SER A 335 VAL A 409 VAL A 381	None	1.11A	5dpdA-4j5uA: undetectable	5dpdA-4j5uA: 22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DZK_1_BEZ1801_0 (ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 BEZ-LEU-LEU)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	3 / 3	LEU A 415 PHE A 373 ILE A 413	None	0.77A	5dzk1-4j5uA: undetectable 5dzkF-4j5uA: undetectable 5dzkM-4j5uA: undetectable	5dzk1-4j5uA: 3.92 5dzkF-4j5uA: 21.34 5dzkM-4j5uA: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DZK_4_BEZ4801_0 (ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 BEZ-LEU-LEU)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	4 / 5	LEU A 415 PHE A 373 ILE A 413 ILE A 30	None	0.87A	5dzk4-4j5uA: undetectable 5dzkg-4j5uA: undetectable 5dzkm-4j5uA: undetectable 5dzkn-4j5uA: undetectable	5dzk4-4j5uA: 3.92 5dzkg-4j5uA: 21.34 5dzkm-4j5uA: 20.00 5dzkn-4j5uA: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LF7_V_6V8V303_0 (PROTEASOME SUBUNIT BETA TYPE-3 PROTEASOME SUBUNIT BETA TYPE-7)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	5 / 11	ALA A 177 GLY A 360 ALA A 347 THR A 358 ASP A 122	None	1.13A	5lf7V-4j5uA: undetectable 5lf7W-4j5uA: undetectable	5lf7V-4j5uA: 21.90 5lf7W-4j5uA: 18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5OG9_A_TESA504_1 (-)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	5 / 8	ILE A 30 VAL A 385 THR A 313 ALA A 294 LEU A 363	None	1.36A	5og9A-4j5uA: undetectable	5og9A-4j5uA: 25.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5QGK_A_ACTA301_0 (PEROXISOMAL COENZYME A DIPHOSPHATASE NUDT7)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	3 / 3	VAL A 320 TYR A 306 GLN A 302	None	0.57A	5qgkA-4j5uA: undetectable	5qgkA-4j5uA: 18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5QGR_A_ACTA301_0 (PEROXISOMAL COENZYME A DIPHOSPHATASE NUDT7)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	3 / 3	VAL A 320 TYR A 306 GLN A 302	None	0.61A	5qgrA-4j5uA: undetectable	5qgrA-4j5uA: 18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5QGT_A_ACTA301_0 (PEROXISOMAL COENZYME A DIPHOSPHATASE NUDT7)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	3 / 3	VAL A 320 TYR A 306 GLN A 302	None	0.64A	5qgtA-4j5uA: undetectable	5qgtA-4j5uA: 18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VLM_F_CVIF301_0 (REGULATORY PROTEIN TETR)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	5 / 12	ALA A 347 GLY A 360 SER A 359 ASP A 307 TYR A 306	None	1.46A	5vlmF-4j5uA: 2.3	5vlmF-4j5uA: 18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XPR_A_K86A1201_1 (ENDOTHELIN B RECEPTOR,ENDOLYSIN,E NDOTHELIN B RECEPTOR)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	5 / 12	VAL A 320 LEU A 32 LEU A 336 ILE A 388 ALA A 332	None	1.44A	5xprA-4j5uA: undetectable	5xprA-4j5uA: 21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DJ1_B_AB1B201_1 (HIV-1 PROTEASE)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	5 / 12	ALA A 173 ASP A 201 VAL A 224 ILE A 202 PRO A 219	None LLP A 230 ( 2.9A) None None None	0.93A	6dj1B-4j5uA: undetectable	6dj1B-4j5uA: 12.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DJ2_B_AB1B201_1 (HIV-1 PROTEASE)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	5 / 12	ALA A 173 ASP A 201 VAL A 224 ILE A 202 PRO A 219	None LLP A 230 ( 2.9A) None None None	0.92A	6dj2B-4j5uA: undetectable	6dj2B-4j5uA: 11.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6HD6_A_STIA603_1 (TYROSINE-PROTEIN KINASE ABL1)	4j5u	SERINE HYDROXYMETHYLTRANSFE RASE (Rickettsia rickettsii)	4 / 5	LEU A 127 ILE A 251 MET A 135 GLY A 137	None	0.94A	6hd6A-4j5uA: undetectable	6hd6A-4j5uA: 11.23

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1DFO_A_FFOA1002_0","SERINE HYDROXYMETHYLTRANSFERASE","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",7,"GLY A 124;SER A 176;ALA A 177;ASN A 346;SER A 354;PRO A 355;ARG A 362","None","1.07A","1dfoA-4j5uA:59.7","1dfoA-4j5uA:56.03"],["1DFO_A_FFOA1002_0","SERINE HYDROXYMETHYLTRANSFERASE","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",7,"GLY A 124;SER A 176;ALA A 177;SER A 354;PRO A 355;PHE A 356;ARG A 362","None","0.95A","1dfoA-4j5uA:59.7","1dfoA-4j5uA:56.03"],["1DFO_A_FFOA1002_0","SERINE HYDROXYMETHYLTRANSFERASE","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",7,"LEU A 121;GLY A 124;HIS A 126;LEU A 127;SER A 176;ALA A 177;ARG A 362","None;None;LLP A 230 ( 3.5A);None;None;None;None","0.97A","1dfoA-4j5uA:59.7","1dfoA-4j5uA:56.03"],["1DFO_A_FFOA1002_0","SERINE HYDROXYMETHYLTRANSFERASE","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",7,"LEU A 121;GLY A 124;SER A 176;ALA A 177;SER A 354;PHE A 356;ARG A 362","None","1.12A","1dfoA-4j5uA:59.7","1dfoA-4j5uA:56.03"],["1DFO_A_FFOA1002_1","SERINE HYDROXYMETHYLTRANSFERASE","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",4,"GLU A  57;TYR A  65;PHE A 256;PRO A 257","None","0.40A","1dfoB-4j5uA:60.9","1dfoB-4j5uA:56.03"],["1DFO_B_FFOB2002_0","SERINE HYDROXYMETHYLTRANSFERASE","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",4,"GLU A  57;TYR A  65;PHE A 256;PRO A 257","None","0.40A","1dfoA-4j5uA:59.7","1dfoA-4j5uA:56.03"],["1DFO_B_FFOB2002_1","SERINE HYDROXYMETHYLTRANSFERASE","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",7,"GLY A 124;SER A 176;ALA A 177;ASN A 346;SER A 354;PRO A 355;ARG A 362","None","1.07A","1dfoB-4j5uA:60.9","1dfoB-4j5uA:56.03"],["1DFO_B_FFOB2002_1","SERINE HYDROXYMETHYLTRANSFERASE","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",7,"GLY A 124;SER A 176;ALA A 177;SER A 354;PRO A 355;PHE A 356;ARG A 362","None","0.96A","1dfoB-4j5uA:60.9","1dfoB-4j5uA:56.03"],["1DFO_B_FFOB2002_1","SERINE HYDROXYMETHYLTRANSFERASE","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",7,"LEU A 121;GLY A 124;HIS A 126;LEU A 127;SER A 176;ALA A 177;ARG A 362","None;None;LLP A 230 ( 3.5A);None;None;None;None","0.97A","1dfoB-4j5uA:60.9","1dfoB-4j5uA:56.03"],["1DFO_B_FFOB2002_1","SERINE HYDROXYMETHYLTRANSFERASE","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",7,"LEU A 121;GLY A 124;SER A 176;ALA A 177;SER A 354;PHE A 356;ARG A 362","None","1.12A","1dfoB-4j5uA:60.9","1dfoB-4j5uA:56.03"],["1DFO_C_FFOC3002_1","SERINE HYDROXYMETHYLTRANSFERASE","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",7,"GLY A 124;SER A 176;ALA A 177;ASN A 346;SER A 354;PRO A 355;ARG A 362","None","1.07A","1dfoC-4j5uA:60.9","1dfoC-4j5uA:56.03"],["1DFO_C_FFOC3002_1","SERINE HYDROXYMETHYLTRANSFERASE","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",7,"GLY A 124;SER A 176;ALA A 177;SER A 354;PRO A 355;PHE A 356;ARG A 362","None","0.95A","1dfoC-4j5uA:60.9","1dfoC-4j5uA:56.03"],["1DFO_C_FFOC3002_1","SERINE HYDROXYMETHYLTRANSFERASE","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",7,"LEU A 121;GLY A 124;HIS A 126;LEU A 127;SER A 176;ALA A 177;ARG A 362","None;None;LLP A 230 ( 3.5A);None;None;None;None","0.96A","1dfoC-4j5uA:60.9","1dfoC-4j5uA:56.03"],["1DFO_C_FFOC3002_1","SERINE HYDROXYMETHYLTRANSFERASE","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",7,"LEU A 121;GLY A 124;SER A 176;ALA A 177;SER A 354;PHE A 356;ARG A 362","None","1.12A","1dfoC-4j5uA:60.9","1dfoC-4j5uA:56.03"],["1DFO_C_FFOC3002_2","SERINE HYDROXYMETHYLTRANSFERASE","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",4,"GLU A  57;TYR A  65;PHE A 256;PRO A 257","None","0.40A","1dfoD-4j5uA:59.7","1dfoD-4j5uA:56.03"],["1DFO_D_FFOD4002_0","SERINE HYDROXYMETHYLTRANSFERASE","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",4,"GLU A  57;TYR A  65;PHE A 256;PRO A 257","None","0.40A","1dfoC-4j5uA:60.9","1dfoC-4j5uA:56.03"],["1DFO_D_FFOD4002_1","SERINE HYDROXYMETHYLTRANSFERASE","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",7,"GLY A 124;SER A 176;ALA A 177;ASN A 346;SER A 354;PRO A 355;ARG A 362","None","1.07A","1dfoD-4j5uA:59.7","1dfoD-4j5uA:56.03"],["1DFO_D_FFOD4002_1","SERINE HYDROXYMETHYLTRANSFERASE","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",7,"GLY A 124;SER A 176;ALA A 177;SER A 354;PRO A 355;PHE A 356;ARG A 362","None","0.95A","1dfoD-4j5uA:59.7","1dfoD-4j5uA:56.03"],["1DFO_D_FFOD4002_1","SERINE HYDROXYMETHYLTRANSFERASE","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",7,"LEU A 121;GLY A 124;HIS A 126;LEU A 127;SER A 176;ALA A 177;ARG A 362","None;None;LLP A 230 ( 3.5A);None;None;None;None","0.97A","1dfoD-4j5uA:59.7","1dfoD-4j5uA:56.03"],["1DFO_D_FFOD4002_1","SERINE HYDROXYMETHYLTRANSFERASE","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",7,"LEU A 121;GLY A 124;SER A 176;ALA A 177;SER A 354;PHE A 356;ARG A 362","None","1.12A","1dfoD-4j5uA:59.7","1dfoD-4j5uA:56.03"],["1EQB_A_FFOA1293_0","SERINE HYDROXYMETHYLTRANSFERASE","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",6,"GLY A 124;SER A 176;ALA A 177;ASN A 346;PRO A 355;ARG A 362","None","0.99A","1eqbA-4j5uA:59.6","1eqbA-4j5uA:55.79"],["1EQB_A_FFOA1293_0","SERINE HYDROXYMETHYLTRANSFERASE","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",6,"GLY A 124;SER A 176;ALA A 177;ASN A 346;SER A 354;PRO A 355","None","1.03A","1eqbA-4j5uA:59.6","1eqbA-4j5uA:55.79"],["1EQB_A_FFOA1293_0","SERINE HYDROXYMETHYLTRANSFERASE","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",6,"GLY A 124;SER A 176;ALA A 177;PRO A 355;PHE A 356;ARG A 362","None","0.88A","1eqbA-4j5uA:59.6","1eqbA-4j5uA:55.79"],["1EQB_A_FFOA1293_0","SERINE HYDROXYMETHYLTRANSFERASE","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",6,"GLY A 124;SER A 176;ALA A 177;SER A 354;PRO A 355;PHE A 356","None","0.88A","1eqbA-4j5uA:59.6","1eqbA-4j5uA:55.79"],["1EQB_A_FFOA1293_0","SERINE HYDROXYMETHYLTRANSFERASE","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",7,"LEU A 121;GLY A 124;HIS A 126;LEU A 127;SER A 176;ALA A 177;ARG A 362","None;None;LLP A 230 ( 3.5A);None;None;None;None","0.99A","1eqbA-4j5uA:59.6","1eqbA-4j5uA:55.79"],["1EQB_A_FFOA1293_0","SERINE HYDROXYMETHYLTRANSFERASE","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",6,"LEU A 121;GLY A 124;SER A 176;ALA A 177;PHE A 356;ARG A 362","None","1.04A","1eqbA-4j5uA:59.6","1eqbA-4j5uA:55.79"],["1EQB_A_FFOA1293_0","SERINE HYDROXYMETHYLTRANSFERASE","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",6,"LEU A 121;GLY A 124;SER A 176;ALA A 177;SER A 354;PHE A 356","None","1.05A","1eqbA-4j5uA:59.6","1eqbA-4j5uA:55.79"],["1EQB_A_GLYA1292_0","SERINE HYDROXYMETHYLTRANSFERASE","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",4,"SER A  35;HIS A 126;SER A 176;HIS A 204","LLP A 230 ( 4.9A);LLP A 230 ( 3.5A);None;LLP A 230 ( 4.1A)","0.68A","1eqbA-4j5uA:59.6;1eqbB-4j5uA:60.9","1eqbA-4j5uA:55.79;1eqbB-4j5uA:55.79"],["1EQB_B_FFOB2293_1","SERINE HYDROXYMETHYLTRANSFERASE","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",7,"GLY A 124;SER A 176;ALA A 177;ASN A 346;SER A 354;PRO A 355;ARG A 362","None","1.08A","1eqbB-4j5uA:60.9","1eqbB-4j5uA:55.79"],["1EQB_B_FFOB2293_1","SERINE HYDROXYMETHYLTRANSFERASE","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",7,"GLY A 124;SER A 176;ALA A 177;SER A 354;PRO A 355;PHE A 356;ARG A 362","None","0.96A","1eqbB-4j5uA:60.9","1eqbB-4j5uA:55.79"],["1EQB_B_FFOB2293_1","SERINE HYDROXYMETHYLTRANSFERASE","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",7,"LEU A 121;GLY A 124;HIS A 126;LEU A 127;SER A 176;ALA A 177;ARG A 362","None;None;LLP A 230 ( 3.5A);None;None;None;None","0.99A","1eqbB-4j5uA:60.9","1eqbB-4j5uA:55.79"],["1EQB_B_FFOB2293_1","SERINE HYDROXYMETHYLTRANSFERASE","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",7,"LEU A 121;GLY A 124;SER A 176;ALA A 177;SER A 354;PHE A 356;ARG A 362","None","1.10A","1eqbB-4j5uA:60.9","1eqbB-4j5uA:55.79"],["1EQB_B_FFOB2293_1","SERINE HYDROXYMETHYLTRANSFERASE","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",5,"LEU A 121;SER A 176;ALA A 177;ASN A 346;ARG A 362","None","1.16A","1eqbB-4j5uA:60.9","1eqbB-4j5uA:55.79"],["1EQB_B_GLYB2292_0","SERINE HYDROXYMETHYLTRANSFERASE","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",4,"SER A  35;HIS A 126;SER A 176;HIS A 204","LLP A 230 ( 4.9A);LLP A 230 ( 3.5A);None;LLP A 230 ( 4.1A)","0.69A","1eqbA-4j5uA:59.6;1eqbB-4j5uA:60.9","1eqbA-4j5uA:55.79;1eqbB-4j5uA:55.79"],["1EQB_C_FFOC3293_1","SERINE HYDROXYMETHYLTRANSFERASE","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",6,"GLY A 124;SER A 176;ALA A 177;ASN A 346;PRO A 355;ARG A 362","None","0.99A","1eqbC-4j5uA:60.8","1eqbC-4j5uA:55.79"],["1EQB_C_FFOC3293_1","SERINE HYDROXYMETHYLTRANSFERASE","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",6,"GLY A 124;SER A 176;ALA A 177;ASN A 346;SER A 354;PRO A 355","None","1.03A","1eqbC-4j5uA:60.8","1eqbC-4j5uA:55.79"],["1EQB_C_FFOC3293_1","SERINE HYDROXYMETHYLTRANSFERASE","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",6,"GLY A 124;SER A 176;ALA A 177;PRO A 355;PHE A 356;ARG A 362","None","0.88A","1eqbC-4j5uA:60.8","1eqbC-4j5uA:55.79"],["1EQB_C_FFOC3293_1","SERINE HYDROXYMETHYLTRANSFERASE","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",6,"GLY A 124;SER A 176;ALA A 177;SER A 354;PRO A 355;PHE A 356","None","0.89A","1eqbC-4j5uA:60.8","1eqbC-4j5uA:55.79"],["1EQB_C_FFOC3293_1","SERINE HYDROXYMETHYLTRANSFERASE","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",7,"LEU A 121;GLY A 124;HIS A 126;LEU A 127;SER A 176;ALA A 177;ARG A 362","None;None;LLP A 230 ( 3.5A);None;None;None;None","0.99A","1eqbC-4j5uA:60.8","1eqbC-4j5uA:55.79"],["1EQB_C_FFOC3293_1","SERINE HYDROXYMETHYLTRANSFERASE","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",6,"LEU A 121;GLY A 124;SER A 176;ALA A 177;PHE A 356;ARG A 362","None","1.05A","1eqbC-4j5uA:60.8","1eqbC-4j5uA:55.79"],["1EQB_C_FFOC3293_1","SERINE HYDROXYMETHYLTRANSFERASE","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",6,"LEU A 121;GLY A 124;SER A 176;ALA A 177;SER A 354;PHE A 356","None","1.06A","1eqbC-4j5uA:60.8","1eqbC-4j5uA:55.79"],["1EQB_C_GLYC3292_0","SERINE HYDROXYMETHYLTRANSFERASE","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",4,"SER A  35;HIS A 126;SER A 176;HIS A 204","LLP A 230 ( 4.9A);LLP A 230 ( 3.5A);None;LLP A 230 ( 4.1A)","0.69A","1eqbC-4j5uA:60.8;1eqbD-4j5uA:60.8","1eqbC-4j5uA:55.79;1eqbD-4j5uA:55.79"],["1EQB_D_FFOD4293_1","SERINE HYDROXYMETHYLTRANSFERASE","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",7,"GLY A 124;SER A 176;ALA A 177;ASN A 346;SER A 354;PRO A 355;ARG A 362","None","1.08A","1eqbD-4j5uA:60.8","1eqbD-4j5uA:55.79"],["1EQB_D_FFOD4293_1","SERINE HYDROXYMETHYLTRANSFERASE","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",7,"GLY A 124;SER A 176;ALA A 177;SER A 354;PRO A 355;PHE A 356;ARG A 362","None","0.96A","1eqbD-4j5uA:60.8","1eqbD-4j5uA:55.79"],["1EQB_D_FFOD4293_1","SERINE HYDROXYMETHYLTRANSFERASE","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",7,"LEU A 121;GLY A 124;HIS A 126;LEU A 127;SER A 176;ALA A 177;ARG A 362","None;None;LLP A 230 ( 3.5A);None;None;None;None","0.99A","1eqbD-4j5uA:60.8","1eqbD-4j5uA:55.79"],["1EQB_D_FFOD4293_1","SERINE HYDROXYMETHYLTRANSFERASE","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",7,"LEU A 121;GLY A 124;SER A 176;ALA A 177;SER A 354;PHE A 356;ARG A 362","None","1.10A","1eqbD-4j5uA:60.8","1eqbD-4j5uA:55.79"],["1EQB_D_GLYD4292_0","SERINE HYDROXYMETHYLTRANSFERASE","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",4,"SER A  35;HIS A 126;SER A 176;HIS A 204","LLP A 230 ( 4.9A);LLP A 230 ( 3.5A);None;LLP A 230 ( 4.1A)","0.69A","1eqbC-4j5uA:60.8;1eqbD-4j5uA:60.8","1eqbC-4j5uA:55.79;1eqbD-4j5uA:55.79"],["1EQG_A_IBPA701_1","PROSTAGLANDIN H2 SYNTHASE-1","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",5,"TYR A 306;ILE A 327;ALA A 332;SER A 335;LEU A 336","None","1.13A","1eqgA-4j5uA:undetectable","1eqgA-4j5uA:22.28"],["1EQG_B_IBPB1701_1","PROSTAGLANDIN H2 SYNTHASE-1","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",5,"TYR A 306;ILE A 327;ALA A 332;SER A 335;LEU A 336","None","1.14A","1eqgB-4j5uA:undetectable","1eqgB-4j5uA:22.28"],["1N49_D_RITD401_1","PROTEASE;PROTEASE","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",5,"ALA A 173;ASP A 201;VAL A 224;ILE A 202;PRO A 219","None;LLP A 230 ( 2.9A);None;None;None","0.95A","1n49C-4j5uA:undetectable","1n49C-4j5uA:14.52"],["1Q23_C_FUAC701_1","CHLORAMPHENICOL ACETYLTRANSFERASE;CHLORAMPHENICOL ACETYLTRANSFERASE","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",4,"ALA A  46;VAL A 273;ALA A 270;HIS A 266","None","1.10A","1q23A-4j5uA:undetectable","1q23A-4j5uA:19.43"],["1TDN_A_LEUA487_0","L-AMINO ACID OXIDASE","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",4,"ASN A 134;HIS A 126;TYR A 106;ILE A 172","None;LLP A 230 ( 3.5A);None;None","1.37A","1tdnA-4j5uA:undetectable","1tdnA-4j5uA:25.79"],["1UKB_A_BEZA1300_0","2-HYDROXY-6-OXO-7-METHYLOCTA-2,4-DIENOATE HYDROLASE","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",5,"GLY A 238;SER A  97;ALA A 101;ALA A 104;LEU A 259","None;LLP A 230 ( 3.4A);None;None;None","1.16A","1ukbA-4j5uA:undetectable","1ukbA-4j5uA:22.99"],["2CEO_B_T44B1395_1","THYROXINE-BINDING GLOBULIN","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",5,"ALA A 339;LEU A 301;LEU A 363;SER A 335;LEU A 336","None","1.39A","2ceoB-4j5uA:undetectable","2ceoB-4j5uA:22.46"],["2Q5K_A_AB1A201_2","PROTEASE;PROTEASE","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",5,"ALA A 173;ASP A 201;VAL A 224;ILE A 202;PRO A 219","None;LLP A 230 ( 2.9A);None;None;None","0.81A","2q5kB-4j5uA:undetectable","2q5kB-4j5uA:13.81"],["2VMY_A_FFOA505_0","SERINE HYDROXYMETHYLTRANSFERASE","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",4,"GLU A  57;TYR A  65;PHE A 256;PRO A 257","None","0.40A","2vmyA-4j5uA:60.2","2vmyA-4j5uA:57.69"],["2VMY_A_FFOA505_1","SERINE HYDROXYMETHYLTRANSFERASE","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",5,"GLY A 124;ALA A 177;ASN A 346;PRO A 355;ARG A 362","None","0.86A","2vmyB-4j5uA:60.1","2vmyB-4j5uA:57.69"],["2VMY_A_FFOA505_1","SERINE HYDROXYMETHYLTRANSFERASE","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",5,"GLY A 124;ALA A 177;ASN A 346;SER A 354;PRO A 355","None","1.02A","2vmyB-4j5uA:60.1","2vmyB-4j5uA:57.69"],["2VMY_A_FFOA505_1","SERINE HYDROXYMETHYLTRANSFERASE","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",6,"LEU A 121;GLY A 124;HIS A 126;LEU A 127;ALA A 177;ARG A 362","None;None;LLP A 230 ( 3.5A);None;None;None","0.97A","2vmyB-4j5uA:60.1","2vmyB-4j5uA:57.69"],["2VMY_A_FFOA505_1","SERINE HYDROXYMETHYLTRANSFERASE","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",5,"LEU A 121;HIS A 126;LEU A 127;SER A 176;ARG A 362","None;LLP A 230 ( 3.5A);None;None;None","1.02A","2vmyB-4j5uA:60.1","2vmyB-4j5uA:57.69"],["2VMY_B_FFOB505_0","SERINE HYDROXYMETHYLTRANSFERASE","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",5,"GLY A 124;ALA A 177;SER A 354;PRO A 355;ARG A 362","None","1.01A","2vmyA-4j5uA:60.2","2vmyA-4j5uA:57.69"],["2VMY_B_FFOB505_0","SERINE HYDROXYMETHYLTRANSFERASE","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",5,"GLY A 124;SER A 176;ALA A 177;PRO A 355;ARG A 362","None","0.99A","2vmyA-4j5uA:60.2","2vmyA-4j5uA:57.69"],["2VMY_B_FFOB505_0","SERINE HYDROXYMETHYLTRANSFERASE","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",7,"LEU A 121;GLY A 124;HIS A 126;LEU A 127;SER A 176;ALA A 177;ARG A 362","None;None;LLP A 230 ( 3.5A);None;None;None;None","0.99A","2vmyA-4j5uA:60.2","2vmyA-4j5uA:57.69"],["2VMY_B_FFOB505_0","SERINE HYDROXYMETHYLTRANSFERASE","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",7,"LEU A 121;HIS A 126;LEU A 127;SER A 176;ALA A 177;ASN A 344;ARG A 362","None;LLP A 230 ( 3.5A);None;None;None;None;None","1.16A","2vmyA-4j5uA:60.2","2vmyA-4j5uA:57.69"],["2VMY_B_GLYB502_0","SERINE HYDROXYMETHYLTRANSFERASE","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",4,"SER A  35;HIS A 126;SER A 176;HIS A 204","LLP A 230 ( 4.9A);LLP A 230 ( 3.5A);None;LLP A 230 ( 4.1A)","0.68A","2vmyA-4j5uA:60.2;2vmyB-4j5uA:60.1","2vmyA-4j5uA:57.69;2vmyB-4j5uA:57.69"],["3LUS_B_X8ZB1001_1","ORGANIC HYDROPEROXIDE RESISTANCE PROTEIN;ORGANIC HYDROPEROXIDE RESISTANCE PROTEIN","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",5,"ASN A  92;ALA A  91;TYR A  59;PRO A 263;PRO A  95","None","1.40A","3lusA-4j5uA:0.9;3lusB-4j5uA:0.0","3lusA-4j5uA:17.03;3lusB-4j5uA:17.03"],["3NUJ_B_478B401_1","PROTEASE;PROTEASE","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",5,"ALA A 173;ASP A 201;VAL A 224;ILE A 202;PRO A 219","None;LLP A 230 ( 2.9A);None;None;None","0.99A","3nujA-4j5uA:undetectable","3nujA-4j5uA:14.01"],["3OXX_A_DR7A100_2","HIV-1 PROTEASE;HIV-1 PROTEASE","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",5,"ALA A 333;ASP A 337;ILE A 341;VAL A 320;ILE A 361","None","1.32A","3oxxB-4j5uA:undetectable","3oxxB-4j5uA:14.11"],["3QF1_A_PZEA6951_1","LACTOPEROXIDASE","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",3,"HIS A 383;ARG A 304;GLU A 303","None","1.13A","3qf1A-4j5uA:undetectable","3qf1A-4j5uA:20.89"],["3SPK_A_TPVA100_1","HIV-1 PROTEASE","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",5,"ALA A 347;ASP A 351;ILE A 357;GLY A 329;ILE A 361","None","1.13A","3spkA-4j5uA:undetectable","3spkA-4j5uA:13.88"],["3TL9_A_ROCA401_4","PROTEASE;PROTEASE","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",4,"ASP A 307;ASP A 321;GLY A 326;THR A 358","None","1.33A","3tl9B-4j5uA:undetectable","3tl9B-4j5uA:15.50"],["3V4T_H_ACTH503_0","UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",4,"ALA A 347;ILE A 348;ARG A 362;GLY A 329","None","1.01A","3v4tH-4j5uA:undetectable","3v4tH-4j5uA:24.16"],["4DM8_A_REAA501_1","RETINOIC ACID RECEPTOR BETA","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",5,"LEU A 336;ILE A 361;SER A  35;LEU A 301;ILE A  30","None;None;LLP A 230 ( 4.9A);None;None","1.03A","4dm8A-4j5uA:undetectable","4dm8A-4j5uA:21.50"],["4DTZ_B_LDPB501_1","CYTOCHROME P450 BM3 VARIANT 8C8","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",4,"PHE A  86;ALA A 210;LEU A 232;THR A 231","None;None;None;LLP A 230 ( 4.0A)","1.13A","4dtzB-4j5uA:undetectable","4dtzB-4j5uA:25.39"],["4HTF_A_SAMA301_0","S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",5,"GLY A 340;LEU A 336;SER A 335;VAL A 409;VAL A 381","None","0.92A","4htfA-4j5uA:undetectable","4htfA-4j5uA:23.63"],["4HTF_B_SAMB301_0","S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",5,"GLY A 340;LEU A 336;SER A 335;VAL A 409;VAL A 381","None","0.95A","4htfB-4j5uA:3.3","4htfB-4j5uA:23.63"],["4PCL_B_SAMB301_0","O-METHYLTRANSFERASE FAMILY PROTEIN","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",5,"GLN A  94;LEU A 264;GLY A 238;ALA A 203;ASN A 102","None;None;None;LLP A 230 ( 3.4A);LLP A 230 ( 4.5A)","1.27A","4pclB-4j5uA:4.3","4pclB-4j5uA:18.75"],["4RMJ_A_NCAA402_0","NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-2","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",4,"PHE A 198;LEU A 171;ILE A 182;ASP A 183","None","0.87A","4rmjA-4j5uA:2.0","4rmjA-4j5uA:22.30"],["4RZV_A_032A801_2","SERINE\/THREONINE-PROTEIN KINASE B-RAF","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",4,"ILE A 251;VAL A 105;PHE A 187;HIS A 249","None","1.20A","4rzvA-4j5uA:undetectable","4rzvA-4j5uA:21.58"],["4TWD_A_377A402_1","CYS-LOOP LIGAND-GATED ION CHANNEL;CYS-LOOP LIGAND-GATED ION CHANNEL;CYS-LOOP LIGAND-GATED ION CHANNEL;CYS-LOOP LIGAND-GATED ION CHANNEL;CYS-LOOP LIGAND-GATED ION CHANNEL","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",5,"ALA A 269;ALA A  46;ALA A  42;SER A  40;ALA A 272","None","1.33A","4twdA-4j5uA:undetectable;4twdB-4j5uA:undetectable;4twdC-4j5uA:undetectable;4twdD-4j5uA:undetectable;4twdE-4j5uA:undetectable","4twdA-4j5uA:23.15;4twdB-4j5uA:23.15;4twdC-4j5uA:23.15;4twdD-4j5uA:23.15;4twdE-4j5uA:23.15"],["4UBE_A_2FAA401_2","ADENOSINE KINASE","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",4,"ALA A 272;VAL A  93;GLY A 238;THR A 228","None","1.14A","4ubeA-4j5uA:4.3","4ubeA-4j5uA:22.25"],["4X1F_A_3WFA501_1","NUCLEAR RECEPTOR SUBFAMILY 1 GROUP I MEMBER 2","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",5,"LEU A 322;LEU A 389;SER A 300;LEU A 363;ILE A 361","None","1.09A","4x1fA-4j5uA:undetectable","4x1fA-4j5uA:21.68"],["4X1G_A_3WFA501_1","NUCLEAR RECEPTOR SUBFAMILY 1 GROUP I MEMBER 2","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",5,"LEU A 322;LEU A 389;SER A 300;LEU A 363;ILE A 361","None","1.09A","4x1gA-4j5uA:undetectable","4x1gA-4j5uA:21.68"],["5DPD_A_SAMA601_0","PROTEIN LYSINE METHYLTRANSFERASE 1","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",5,"GLY A 340;LEU A 336;SER A 335;VAL A 409;VAL A 381","None","1.11A","5dpdA-4j5uA:undetectable","5dpdA-4j5uA:22.13"],["5DZK_1_BEZ1801_0","ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1;ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2;BEZ-LEU-LEU","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",3,"LEU A 415;PHE A 373;ILE A 413","None","0.77A","5dzk1-4j5uA:undetectable;5dzkF-4j5uA:undetectable;5dzkM-4j5uA:undetectable","5dzk1-4j5uA:3.92;5dzkF-4j5uA:21.34;5dzkM-4j5uA:20.00"],["5DZK_4_BEZ4801_0","ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1;ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2;BEZ-LEU-LEU","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",4,"LEU A 415;PHE A 373;ILE A 413;ILE A  30","None","0.87A","5dzk4-4j5uA:undetectable;5dzkg-4j5uA:undetectable;5dzkm-4j5uA:undetectable;5dzkn-4j5uA:undetectable","5dzk4-4j5uA:3.92;5dzkg-4j5uA:21.34;5dzkm-4j5uA:20.00;5dzkn-4j5uA:20.00"],["5LF7_V_6V8V303_0","PROTEASOME SUBUNIT BETA TYPE-3;PROTEASOME SUBUNIT BETA TYPE-7","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",5,"ALA A 177;GLY A 360;ALA A 347;THR A 358;ASP A 122","None","1.13A","5lf7V-4j5uA:undetectable;5lf7W-4j5uA:undetectable","5lf7V-4j5uA:21.90;5lf7W-4j5uA:18.14"],["5OG9_A_TESA504_1","-","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",5,"ILE A  30;VAL A 385;THR A 313;ALA A 294;LEU A 363","None","1.36A","5og9A-4j5uA:undetectable","5og9A-4j5uA:25.49"],["5QGK_A_ACTA301_0","PEROXISOMAL COENZYME A DIPHOSPHATASE NUDT7","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",3,"VAL A 320;TYR A 306;GLN A 302","None","0.57A","5qgkA-4j5uA:undetectable","5qgkA-4j5uA:18.09"],["5QGR_A_ACTA301_0","PEROXISOMAL COENZYME A DIPHOSPHATASE NUDT7","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",3,"VAL A 320;TYR A 306;GLN A 302","None","0.61A","5qgrA-4j5uA:undetectable","5qgrA-4j5uA:18.09"],["5QGT_A_ACTA301_0","PEROXISOMAL COENZYME A DIPHOSPHATASE NUDT7","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",3,"VAL A 320;TYR A 306;GLN A 302","None","0.64A","5qgtA-4j5uA:undetectable","5qgtA-4j5uA:18.09"],["5VLM_F_CVIF301_0","REGULATORY PROTEIN TETR","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",5,"ALA A 347;GLY A 360;SER A 359;ASP A 307;TYR A 306","None","1.46A","5vlmF-4j5uA:2.3","5vlmF-4j5uA:18.71"],["5XPR_A_K86A1201_1","ENDOTHELIN B RECEPTOR,ENDOLYSIN,ENDOTHELIN B RECEPTOR","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",5,"VAL A 320;LEU A  32;LEU A 336;ILE A 388;ALA A 332","None","1.44A","5xprA-4j5uA:undetectable","5xprA-4j5uA:21.18"],["6DJ1_B_AB1B201_1","HIV-1 PROTEASE","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",5,"ALA A 173;ASP A 201;VAL A 224;ILE A 202;PRO A 219","None;LLP A 230 ( 2.9A);None;None;None","0.93A","6dj1B-4j5uA:undetectable","6dj1B-4j5uA:12.05"],["6DJ2_B_AB1B201_1","HIV-1 PROTEASE","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",5,"ALA A 173;ASP A 201;VAL A 224;ILE A 202;PRO A 219","None;LLP A 230 ( 2.9A);None;None;None","0.92A","6dj2B-4j5uA:undetectable","6dj2B-4j5uA:11.81"],["6HD6_A_STIA603_1","TYROSINE-PROTEIN KINASE ABL1","4j5u","SERINE HYDROXYMETHYLTRANSFERASE","Rickettsia rickettsii",4,"LEU A 127;ILE A 251;MET A 135;GLY A 137","None","0.94A","6hd6A-4j5uA:undetectable","6hd6A-4j5uA:11.23"]]