SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4j6p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_D_DVAD8_0
(GRAMICIDIN A)		 4j6p LOW AFFINITY
IMMUNOGLOBULIN
EPSILON FC RECEPTOR
(Homo
sapiens) 		3 / 3 TRP A 220
VAL A 199
TRP A 184
 None
 1.28A 1c4dC-4j6pA:
undetectable
1c4dD-4j6pA:
undetectable		 1c4dC-4j6pA:
10.00
1c4dD-4j6pA:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_D_DVAD8_0
(GRAMICIDIN A)		 4j6p LOW AFFINITY
IMMUNOGLOBULIN
EPSILON FC RECEPTOR
(Homo
sapiens) 		3 / 3 TRP A 220
VAL A 281
TRP A 184
 None
 1.35A 1c4dC-4j6pA:
undetectable
1c4dD-4j6pA:
undetectable		 1c4dC-4j6pA:
10.00
1c4dD-4j6pA:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_A_DVAA8_0
(GRAMICIDIN A)		 4j6p LOW AFFINITY
IMMUNOGLOBULIN
EPSILON FC RECEPTOR
(Homo
sapiens) 		3 / 3 VAL A 281
TRP A 184
TRP A 220
 None
 1.22A 2xdcA-4j6pA:
undetectable
2xdcB-4j6pA:
undetectable		 2xdcA-4j6pA:
10.00
2xdcB-4j6pA:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_B_DVAB8_0
(GRAMICIDIN A)		 4j6p LOW AFFINITY
IMMUNOGLOBULIN
EPSILON FC RECEPTOR
(Homo
sapiens) 		3 / 3 TRP A 220
VAL A 281
TRP A 184
 None
 1.23A 2xdcA-4j6pA:
undetectable
2xdcB-4j6pA:
undetectable		 2xdcA-4j6pA:
10.00
2xdcB-4j6pA:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_C_DVAC8_0
(GRAMICIDIN A)		 4j6p LOW AFFINITY
IMMUNOGLOBULIN
EPSILON FC RECEPTOR
(Homo
sapiens) 		3 / 3 VAL A 281
TRP A 184
TRP A 220
 None
 1.28A 2xdcC-4j6pA:
undetectable
2xdcD-4j6pA:
undetectable		 2xdcC-4j6pA:
10.00
2xdcD-4j6pA:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_D_DVAD8_0
(GRAMICIDIN A)		 4j6p LOW AFFINITY
IMMUNOGLOBULIN
EPSILON FC RECEPTOR
(Homo
sapiens) 		3 / 3 TRP A 220
VAL A 281
TRP A 184
 None
 1.00A 2xdcC-4j6pA:
undetectable
2xdcD-4j6pA:
undetectable		 2xdcC-4j6pA:
10.00
2xdcD-4j6pA:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_F_DVAF8_0
(GRAMICIDIN A)		 4j6p LOW AFFINITY
IMMUNOGLOBULIN
EPSILON FC RECEPTOR
(Homo
sapiens) 		3 / 3 TRP A 220
VAL A 281
TRP A 184
 None
 1.03A 2xdcE-4j6pA:
undetectable
2xdcF-4j6pA:
undetectable		 2xdcE-4j6pA:
10.00
2xdcF-4j6pA:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_A_DVAA8_0
(VAL-GRAMICIDIN A)		 4j6p LOW AFFINITY
IMMUNOGLOBULIN
EPSILON FC RECEPTOR
(Homo
sapiens) 		3 / 3 VAL A 281
TRP A 184
TRP A 220
 None
 1.21A 2y5mA-4j6pA:
undetectable
2y5mB-4j6pA:
undetectable		 2y5mA-4j6pA:
10.00
2y5mB-4j6pA:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_F_DVAF8_0
(VAL-GRAMICIDIN A)		 4j6p LOW AFFINITY
IMMUNOGLOBULIN
EPSILON FC RECEPTOR
(Homo
sapiens) 		3 / 3 TRP A 220
VAL A 281
TRP A 184
 None
 1.02A 2y5mE-4j6pA:
undetectable
2y5mF-4j6pA:
undetectable		 2y5mE-4j6pA:
10.00
2y5mF-4j6pA:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_A_DVAA8_0
(VAL-GRAMICIDIN A)		 4j6p LOW AFFINITY
IMMUNOGLOBULIN
EPSILON FC RECEPTOR
(Homo
sapiens) 		3 / 3 VAL A 281
TRP A 184
TRP A 220
 None
 1.20A 2y6nA-4j6pA:
undetectable
2y6nB-4j6pA:
undetectable		 2y6nA-4j6pA:
10.00
2y6nB-4j6pA:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_B_DVAB8_0
(VAL-GRAMICIDIN A)		 4j6p LOW AFFINITY
IMMUNOGLOBULIN
EPSILON FC RECEPTOR
(Homo
sapiens) 		3 / 3 TRP A 220
VAL A 281
TRP A 184
 None
 1.22A 2y6nA-4j6pA:
undetectable
2y6nB-4j6pA:
undetectable		 2y6nA-4j6pA:
10.00
2y6nB-4j6pA:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_D_DVAD8_0
(VAL-GRAMICIDIN A)		 4j6p LOW AFFINITY
IMMUNOGLOBULIN
EPSILON FC RECEPTOR
(Homo
sapiens) 		3 / 3 TRP A 220
VAL A 281
TRP A 184
 None
 1.00A 2y6nC-4j6pA:
undetectable
2y6nD-4j6pA:
undetectable		 2y6nC-4j6pA:
10.00
2y6nD-4j6pA:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_F_DVAF8_0
(VAL-GRAMICIDIN A)		 4j6p LOW AFFINITY
IMMUNOGLOBULIN
EPSILON FC RECEPTOR
(Homo
sapiens) 		3 / 3 TRP A 220
VAL A 281
TRP A 184
 None
 1.00A 2y6nE-4j6pA:
undetectable
2y6nF-4j6pA:
undetectable		 2y6nE-4j6pA:
10.00
2y6nF-4j6pA:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YS6_A_GLYA431_0
(PHOSPHORIBOSYLGLYCIN
AMIDE SYNTHETASE)		 4j6p LOW AFFINITY
IMMUNOGLOBULIN
EPSILON FC RECEPTOR
(Homo
sapiens) 		4 / 8 ASP A 270
GLY A 248
PRO A 250
GLU A 249
 None
 0.97A 2ys6A-4j6pA:
undetectable		 2ys6A-4j6pA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_A_DVAA8_0
(VAL-GRAMICIDIN A)		 4j6p LOW AFFINITY
IMMUNOGLOBULIN
EPSILON FC RECEPTOR
(Homo
sapiens) 		3 / 3 VAL A 281
TRP A 184
TRP A 220
 None
 1.21A 3zq8A-4j6pA:
undetectable
3zq8B-4j6pA:
undetectable		 3zq8A-4j6pA:
10.00
3zq8B-4j6pA:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_D_DVAD8_0
(VAL-GRAMICIDIN A)		 4j6p LOW AFFINITY
IMMUNOGLOBULIN
EPSILON FC RECEPTOR
(Homo
sapiens) 		3 / 3 TRP A 220
VAL A 199
TRP A 184
 None
 0.93A 3zq8C-4j6pA:
undetectable
3zq8D-4j6pA:
undetectable		 3zq8C-4j6pA:
10.00
3zq8D-4j6pA:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JX1_E_CAME502_0
(CAMPHOR
5-MONOOXYGENASE)		 4j6p LOW AFFINITY
IMMUNOGLOBULIN
EPSILON FC RECEPTOR
(Homo
sapiens) 		4 / 5 TYR A 175
THR A 211
PHE A 177
ILE A 201
 None
 1.04A 4jx1E-4j6pA:
undetectable		 4jx1E-4j6pA:
12.98