SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4j72'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GM7_B_PNNB1577_0
(PENICILLIN G ACYLASE
ALPHA SUBUNIT
PENICILLIN G ACYLASE
BETA SUBUNIT)		 4j72 PHOSPHO-N-ACETYLMURA
MOYL-PENTAPEPTIDE-TR
ANSFERASE
(Aquifex
aeolicus) 		4 / 8 SER A 345
PHE A 242
ALA A 209
ILE A 353
 None
 0.90A 1gm7A-4j72A:
1.6
1gm7B-4j72A:
undetectable		 1gm7A-4j72A:
17.74
1gm7B-4j72A:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_C_SAMC2293_0
(GLYCINE
N-METHYLTRANSFERASE)		 4j72 PHOSPHO-N-ACETYLMURA
MOYL-PENTAPEPTIDE-TR
ANSFERASE
(Aquifex
aeolicus) 		5 / 12 ILE A 287
GLY A 211
VAL A 213
ALA A 243
LEU A 104
 None
 0.92A 1kiaC-4j72A:
undetectable		 1kiaC-4j72A:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHU_A_ESTA301_1
(SEX HORMONE-BINDING
GLOBULIN)		 4j72 PHOSPHO-N-ACETYLMURA
MOYL-PENTAPEPTIDE-TR
ANSFERASE
(Aquifex
aeolicus) 		5 / 12 GLY A 267
SER A 185
LEU A 275
ILE A  81
LEU A 244
 None
 1.22A 1lhuA-4j72A:
undetectable		 1lhuA-4j72A:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_B_SAMB802_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 4j72 PHOSPHO-N-ACETYLMURA
MOYL-PENTAPEPTIDE-TR
ANSFERASE
(Aquifex
aeolicus) 		5 / 12 ILE A 271
ASP A 265
GLY A 111
GLY A 114
LEU A  82
 None
MG  A 403 (-2.7A)
None
None
None
 1.10A 1rjdB-4j72A:
undetectable		 1rjdB-4j72A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_C_SAMC803_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 4j72 PHOSPHO-N-ACETYLMURA
MOYL-PENTAPEPTIDE-TR
ANSFERASE
(Aquifex
aeolicus) 		5 / 12 ILE A 271
ASP A 265
GLY A 111
GLY A 114
LEU A  82
 None
MG  A 403 (-2.7A)
None
None
None
 1.09A 1rjdC-4j72A:
undetectable		 1rjdC-4j72A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4N_A_TPVA300_1
(PROTEASE)		 4j72 PHOSPHO-N-ACETYLMURA
MOYL-PENTAPEPTIDE-TR
ANSFERASE
(Aquifex
aeolicus) 		5 / 12 LEU A 104
ILE A 182
GLY A 272
ILE A 271
LEU A 108
 None
 0.90A 2o4nA-4j72A:
undetectable		 2o4nA-4j72A:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q7L_A_TESA155_1
(ANDROGEN RECEPTOR)		 4j72 PHOSPHO-N-ACETYLMURA
MOYL-PENTAPEPTIDE-TR
ANSFERASE
(Aquifex
aeolicus) 		5 / 12 LEU A 191
ASN A 190
LEU A 195
GLY A 194
ARG A 320
 None
 1.42A 2q7lA-4j72A:
undetectable		 2q7lA-4j72A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_D_ASDD1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 4j72 PHOSPHO-N-ACETYLMURA
MOYL-PENTAPEPTIDE-TR
ANSFERASE
(Aquifex
aeolicus) 		4 / 7 ILE A  81
GLY A 267
PHE A 107
PHE A 240
 None
 0.99A 2vctD-4j72A:
undetectable		 2vctD-4j72A:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WQ5_A_MIYA1120_1
(PHOSPHOLIPASE A2,
ACIDIC)		 4j72 PHOSPHO-N-ACETYLMURA
MOYL-PENTAPEPTIDE-TR
ANSFERASE
(Aquifex
aeolicus) 		4 / 7 LEU A 275
ALA A 209
GLY A 211
PHE A 107
 None
 0.77A 2wq5A-4j72A:
0.9		 2wq5A-4j72A:
13.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XPW_A_OTCA222_1
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		 4j72 PHOSPHO-N-ACETYLMURA
MOYL-PENTAPEPTIDE-TR
ANSFERASE
(Aquifex
aeolicus) 		5 / 12 LEU A 210
PHE A 288
VAL A 103
ILE A 182
SER A 185
 None
 1.18A 2xpwA-4j72A:
1.5		 2xpwA-4j72A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_C_CHDC1265_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4j72 PHOSPHO-N-ACETYLMURA
MOYL-PENTAPEPTIDE-TR
ANSFERASE
(Aquifex
aeolicus) 		4 / 5 PHE A 180
PHE A 177
LEU A 158
PHE A 160
 None
 0.94A 2y69C-4j72A:
1.2
2y69J-4j72A:
undetectable		 2y69C-4j72A:
22.37
2y69J-4j72A:
13.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_P_CHDP1265_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4j72 PHOSPHO-N-ACETYLMURA
MOYL-PENTAPEPTIDE-TR
ANSFERASE
(Aquifex
aeolicus) 		4 / 5 PHE A 180
PHE A 177
LEU A 158
PHE A 160
 None
 0.94A 2y69P-4j72A:
1.3
2y69W-4j72A:
undetectable		 2y69P-4j72A:
22.37
2y69W-4j72A:
13.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4j72 PHOSPHO-N-ACETYLMURA
MOYL-PENTAPEPTIDE-TR
ANSFERASE
(Aquifex
aeolicus) 		4 / 6 PHE A 180
PHE A 177
LEU A 158
PHE A 160
 None
 1.01A 3abkP-4j72A:
undetectable
3abkW-4j72A:
undetectable		 3abkP-4j72A:
22.37
3abkW-4j72A:
11.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4j72 PHOSPHO-N-ACETYLMURA
MOYL-PENTAPEPTIDE-TR
ANSFERASE
(Aquifex
aeolicus) 		4 / 6 PHE A 180
PHE A 177
LEU A 158
PHE A 160
 None
 1.06A 3ablP-4j72A:
undetectable
3ablW-4j72A:
undetectable		 3ablP-4j72A:
22.37
3ablW-4j72A:
11.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4j72 PHOSPHO-N-ACETYLMURA
MOYL-PENTAPEPTIDE-TR
ANSFERASE
(Aquifex
aeolicus) 		4 / 5 PHE A 180
PHE A 177
LEU A 158
PHE A 160
 None
 0.98A 3abmC-4j72A:
undetectable
3abmJ-4j72A:
undetectable		 3abmC-4j72A:
22.37
3abmJ-4j72A:
11.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4j72 PHOSPHO-N-ACETYLMURA
MOYL-PENTAPEPTIDE-TR
ANSFERASE
(Aquifex
aeolicus) 		4 / 5 PHE A 180
PHE A 177
LEU A 158
PHE A 160
 None
 0.96A 3abmP-4j72A:
1.2
3abmW-4j72A:
undetectable		 3abmP-4j72A:
22.37
3abmW-4j72A:
11.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4j72 PHOSPHO-N-ACETYLMURA
MOYL-PENTAPEPTIDE-TR
ANSFERASE
(Aquifex
aeolicus) 		4 / 5 PHE A 180
PHE A 177
LEU A 158
PHE A 160
 None
 1.02A 3ag3C-4j72A:
undetectable
3ag3J-4j72A:
undetectable		 3ag3C-4j72A:
22.37
3ag3J-4j72A:
11.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_G_SVRG506_2
(PHOSPHOLIPASE A2)		 4j72 PHOSPHO-N-ACETYLMURA
MOYL-PENTAPEPTIDE-TR
ANSFERASE
(Aquifex
aeolicus) 		4 / 5 VAL A 213
VAL A 212
PHE A 288
ARG A  25
 None
 1.31A 3bjwB-4j72A:
undetectable		 3bjwB-4j72A:
13.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U7S_A_017A202_1
(POL POLYPROTEIN)		 4j72 PHOSPHO-N-ACETYLMURA
MOYL-PENTAPEPTIDE-TR
ANSFERASE
(Aquifex
aeolicus) 		5 / 9 LEU A 104
ILE A 182
GLY A 272
ILE A 271
LEU A 108
 None
 0.97A 3u7sA-4j72A:
undetectable		 3u7sA-4j72A:
13.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B3A_A_TACA222_1
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		 4j72 PHOSPHO-N-ACETYLMURA
MOYL-PENTAPEPTIDE-TR
ANSFERASE
(Aquifex
aeolicus) 		5 / 12 LEU A 210
PHE A 288
VAL A 103
ILE A 182
SER A 185
 None
 1.19A 4b3aA-4j72A:
1.6		 4b3aA-4j72A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BBO_B_ACTB1114_0
(BLR5658 PROTEIN)		 4j72 PHOSPHO-N-ACETYLMURA
MOYL-PENTAPEPTIDE-TR
ANSFERASE
(Aquifex
aeolicus) 		3 / 3 TRP A  95
TRP A 101
THR A 100
 None
 1.21A 4bboB-4j72A:
undetectable		 4bboB-4j72A:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CEV_A_GAIA407_0
(PROTEIN (ARGINASE))		 4j72 PHOSPHO-N-ACETYLMURA
MOYL-PENTAPEPTIDE-TR
ANSFERASE
(Aquifex
aeolicus) 		4 / 6 ARG A 320
HIS A 325
LEU A 332
ASP A 196
 None
NI  A 401 (-3.2A)
None
None
 1.34A 4cevA-4j72A:
undetectable
4cevB-4j72A:
undetectable		 4cevA-4j72A:
22.28
4cevB-4j72A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CEV_C_GAIC409_0
(PROTEIN (ARGINASE))		 4j72 PHOSPHO-N-ACETYLMURA
MOYL-PENTAPEPTIDE-TR
ANSFERASE
(Aquifex
aeolicus) 		4 / 6 ASP A 196
ARG A 320
HIS A 325
LEU A 332
 None
None
NI  A 401 (-3.2A)
None
 1.33A 4cevA-4j72A:
undetectable
4cevC-4j72A:
undetectable		 4cevA-4j72A:
22.28
4cevC-4j72A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CEV_D_GAID410_0
(PROTEIN (ARGINASE))		 4j72 PHOSPHO-N-ACETYLMURA
MOYL-PENTAPEPTIDE-TR
ANSFERASE
(Aquifex
aeolicus) 		4 / 6 ARG A 320
HIS A 325
LEU A 332
ASP A 196
 None
NI  A 401 (-3.2A)
None
None
 1.36A 4cevD-4j72A:
undetectable
4cevE-4j72A:
undetectable		 4cevD-4j72A:
22.28
4cevE-4j72A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CEV_F_GAIF411_0
(PROTEIN (ARGINASE))		 4j72 PHOSPHO-N-ACETYLMURA
MOYL-PENTAPEPTIDE-TR
ANSFERASE
(Aquifex
aeolicus) 		4 / 6 ARG A 320
HIS A 325
LEU A 332
ASP A 196
 None
NI  A 401 (-3.2A)
None
None
 1.35A 4cevE-4j72A:
undetectable
4cevF-4j72A:
undetectable		 4cevE-4j72A:
22.28
4cevF-4j72A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LJ0_A_ACTA505_0
(NAB2)		 4j72 PHOSPHO-N-ACETYLMURA
MOYL-PENTAPEPTIDE-TR
ANSFERASE
(Aquifex
aeolicus) 		3 / 3 LEU A 136
LYS A 133
THR A 132
 None
 0.48A 4lj0A-4j72A:
undetectable		 4lj0A-4j72A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOG_B_ML1B302_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4j72 PHOSPHO-N-ACETYLMURA
MOYL-PENTAPEPTIDE-TR
ANSFERASE
(Aquifex
aeolicus) 		4 / 6 GLY A  78
PHE A 107
ILE A 271
PHE A 240
 None
 0.99A 4qogA-4j72A:
undetectable
4qogB-4j72A:
undetectable		 4qogA-4j72A:
23.02
4qogB-4j72A:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U15_A_0HKA2001_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 4j72 PHOSPHO-N-ACETYLMURA
MOYL-PENTAPEPTIDE-TR
ANSFERASE
(Aquifex
aeolicus) 		5 / 12 ASP A 193
SER A 268
THR A 205
THR A 206
ALA A 207
 None
 1.39A 4u15A-4j72A:
2.4		 4u15A-4j72A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4j72 PHOSPHO-N-ACETYLMURA
MOYL-PENTAPEPTIDE-TR
ANSFERASE
(Aquifex
aeolicus) 		4 / 6 PHE A 180
PHE A 177
LEU A 158
PHE A 160
 None
 1.04A 5b1bC-4j72A:
undetectable
5b1bJ-4j72A:
undetectable		 5b1bC-4j72A:
22.37
5b1bJ-4j72A:
11.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_S_BEZS801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 4j72 PHOSPHO-N-ACETYLMURA
MOYL-PENTAPEPTIDE-TR
ANSFERASE
(Aquifex
aeolicus) 		4 / 6 PHE A 251
MET A 263
LEU A 249
LEU A 252
 None
 1.20A 5dzke-4j72A:
undetectable
5dzks-4j72A:
undetectable		 5dzke-4j72A:
21.51
5dzks-4j72A:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_T_BEZT801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 4j72 PHOSPHO-N-ACETYLMURA
MOYL-PENTAPEPTIDE-TR
ANSFERASE
(Aquifex
aeolicus) 		4 / 8 PHE A 251
MET A 263
LEU A 249
LEU A 252
 None
 1.19A 5dzkF-4j72A:
undetectable
5dzkT-4j72A:
undetectable		 5dzkF-4j72A:
21.51
5dzkT-4j72A:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E4D_B_BEZB202_0
(HYDROXYNITRILE LYASE)		 4j72 PHOSPHO-N-ACETYLMURA
MOYL-PENTAPEPTIDE-TR
ANSFERASE
(Aquifex
aeolicus) 		4 / 7 VAL A 189
THR A 192
LEU A 275
THR A 206
 None
 0.99A 5e4dA-4j72A:
undetectable
5e4dB-4j72A:
undetectable		 5e4dA-4j72A:
20.44
5e4dB-4j72A:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4j72 PHOSPHO-N-ACETYLMURA
MOYL-PENTAPEPTIDE-TR
ANSFERASE
(Aquifex
aeolicus) 		4 / 5 PHE A 180
PHE A 177
LEU A 158
PHE A 160
 None
 0.94A 5wauC-4j72A:
1.3
5wauJ-4j72A:
undetectable		 5wauC-4j72A:
22.37
5wauJ-4j72A:
11.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4j72 PHOSPHO-N-ACETYLMURA
MOYL-PENTAPEPTIDE-TR
ANSFERASE
(Aquifex
aeolicus) 		4 / 5 PHE A 180
PHE A 177
LEU A 158
PHE A 160
 None
 0.95A 5wauc-4j72A:
undetectable
5wauj-4j72A:
undetectable		 5wauc-4j72A:
22.37
5wauj-4j72A:
11.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4j72 PHOSPHO-N-ACETYLMURA
MOYL-PENTAPEPTIDE-TR
ANSFERASE
(Aquifex
aeolicus) 		4 / 5 PHE A 180
PHE A 177
LEU A 158
PHE A 160
 None
 0.95A 5xdqC-4j72A:
undetectable
5xdqJ-4j72A:
undetectable		 5xdqC-4j72A:
22.37
5xdqJ-4j72A:
11.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4j72 PHOSPHO-N-ACETYLMURA
MOYL-PENTAPEPTIDE-TR
ANSFERASE
(Aquifex
aeolicus) 		4 / 5 PHE A 180
PHE A 177
LEU A 158
PHE A 160
 None
 0.99A 5xdqP-4j72A:
1.3
5xdqW-4j72A:
undetectable		 5xdqP-4j72A:
22.37
5xdqW-4j72A:
11.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4j72 PHOSPHO-N-ACETYLMURA
MOYL-PENTAPEPTIDE-TR
ANSFERASE
(Aquifex
aeolicus) 		4 / 6 PHE A 180
PHE A 177
LEU A 158
PHE A 160
 None
 1.03A 5z84P-4j72A:
undetectable
5z84W-4j72A:
undetectable		 5z84P-4j72A:
22.37
5z84W-4j72A:
11.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4j72 PHOSPHO-N-ACETYLMURA
MOYL-PENTAPEPTIDE-TR
ANSFERASE
(Aquifex
aeolicus) 		4 / 6 PHE A 180
PHE A 177
LEU A 158
PHE A 160
 None
 1.07A 5z85P-4j72A:
undetectable
5z85W-4j72A:
undetectable		 5z85P-4j72A:
22.37
5z85W-4j72A:
11.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4j72 PHOSPHO-N-ACETYLMURA
MOYL-PENTAPEPTIDE-TR
ANSFERASE
(Aquifex
aeolicus) 		4 / 6 PHE A 180
PHE A 177
LEU A 158
PHE A 160
 None
 0.96A 5z86C-4j72A:
undetectable
5z86J-4j72A:
undetectable		 5z86C-4j72A:
22.37
5z86J-4j72A:
11.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4j72 PHOSPHO-N-ACETYLMURA
MOYL-PENTAPEPTIDE-TR
ANSFERASE
(Aquifex
aeolicus) 		4 / 6 PHE A 180
PHE A 177
LEU A 158
PHE A 160
 None
 1.01A 5z86P-4j72A:
undetectable
5z86W-4j72A:
undetectable		 5z86P-4j72A:
22.37
5z86W-4j72A:
11.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4j72 PHOSPHO-N-ACETYLMURA
MOYL-PENTAPEPTIDE-TR
ANSFERASE
(Aquifex
aeolicus) 		4 / 6 PHE A 180
PHE A 177
LEU A 158
PHE A 160
 None
 1.04A 5zcoP-4j72A:
undetectable
5zcoW-4j72A:
undetectable		 5zcoP-4j72A:
22.37
5zcoW-4j72A:
11.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4j72 PHOSPHO-N-ACETYLMURA
MOYL-PENTAPEPTIDE-TR
ANSFERASE
(Aquifex
aeolicus) 		4 / 6 PHE A 180
PHE A 177
LEU A 158
PHE A 160
 None
 0.96A 5zcpC-4j72A:
undetectable
5zcpJ-4j72A:
undetectable		 5zcpC-4j72A:
22.37
5zcpJ-4j72A:
11.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4j72 PHOSPHO-N-ACETYLMURA
MOYL-PENTAPEPTIDE-TR
ANSFERASE
(Aquifex
aeolicus) 		4 / 6 PHE A 180
PHE A 177
LEU A 158
PHE A 160
 None
 1.02A 5zcpP-4j72A:
undetectable
5zcpW-4j72A:
undetectable		 5zcpP-4j72A:
22.37
5zcpW-4j72A:
11.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FOS_B_PQNB2002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 4j72 PHOSPHO-N-ACETYLMURA
MOYL-PENTAPEPTIDE-TR
ANSFERASE
(Aquifex
aeolicus) 		4 / 6 MET A 355
ALA A 292
LEU A 348
ALA A 349
 None
 1.15A 6fosB-4j72A:
undetectable		 6fosB-4j72A:
11.23