SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4j7o'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG1_A_SPMA999_1
(TYROSYL-DNA
PHOSPHODIESTERASE 1)		 4j7o PUTATIVE SURFACE
CELL ANTIGEN SCA2
(Rickettsia
conorii) 		3 / 3 TRP A  70
VAL A  76
PRO A  77
 None
GOL  A 502 (-3.7A)
None
 0.82A 1rg1A-4j7oA:
undetectable		 1rg1A-4j7oA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RH0_A_SPMA999_1
(TYROSYL-DNA
PHOSPHODIESTERASE 1)		 4j7o PUTATIVE SURFACE
CELL ANTIGEN SCA2
(Rickettsia
conorii) 		3 / 3 TRP A  70
VAL A  76
PRO A  77
 None
GOL  A 502 (-3.7A)
None
 0.82A 1rh0A-4j7oA:
undetectable		 1rh0A-4j7oA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JZ0_B_CLYB900_1
(LINCOSAMIDE
NUCLEOTIDYLTRANSFERA
SE)		 4j7o PUTATIVE SURFACE
CELL ANTIGEN SCA2
(Rickettsia
conorii) 		4 / 8 TYR A 321
TYR A 320
GLU A 336
ILE A 355
 None
 0.91A 3jz0B-4j7oA:
undetectable		 3jz0B-4j7oA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ONN_A_ACTA270_0
(PROTEIN SSM1)		 4j7o PUTATIVE SURFACE
CELL ANTIGEN SCA2
(Rickettsia
conorii) 		4 / 5 LEU A 180
SER A 184
ARG A 187
LEU A 115
 None
 1.19A 3onnA-4j7oA:
undetectable		 3onnA-4j7oA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y03_A_SALA801_1
(PROTEIN POLYBROMO-1)		 4j7o PUTATIVE SURFACE
CELL ANTIGEN SCA2
(Rickettsia
conorii) 		4 / 7 LEU A 248
TYR A 263
ALA A 232
ILE A 228
 None
 0.84A 4y03A-4j7oA:
undetectable		 4y03A-4j7oA:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8P_A_ACTA816_0
(UNCHARACTERIZED
PROTEIN)		 4j7o PUTATIVE SURFACE
CELL ANTIGEN SCA2
(Rickettsia
conorii) 		3 / 3 ARG A 110
ARG A 107
ASP A 173
 GOL  A 501 (-2.9A)
GOL  A 504 (-2.9A)
None
 0.76A 6d8pA-4j7oA:
undetectable		 6d8pA-4j7oA:
17.54