SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4j80'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_D_THAD4_2
(LIVER
CARBOXYLESTERASE I)		 4j80 CHAPERONE PROTEIN
DNAJ 2
(Thermus
thermophilus) 		3 / 3 PHE A 179
LEU A 242
MET A 226
 None
 0.87A 1mx1D-4j80A:
undetectable		 1mx1D-4j80A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LTW_A_486A303_1
(ANCESTRAL STEROID
RECEPTOR 2)		 4j80 CHAPERONE PROTEIN
DNAJ 2
(Thermus
thermophilus) 		5 / 9 LEU A 242
ALA A 188
LEU A 190
THR A 207
LEU A 208
 None
 1.30A 4ltwA-4j80A:
undetectable		 4ltwA-4j80A:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4j80 CHAPERONE PROTEIN
DNAJ 2
(Thermus
thermophilus) 		4 / 7 ILE A 152
LEU A 169
ARG A 147
LEU A 118
 None
 0.98A 5b1bA-4j80A:
undetectable
5b1bJ-4j80A:
undetectable		 5b1bA-4j80A:
18.79
5b1bJ-4j80A:
10.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4j80 CHAPERONE PROTEIN
DNAJ 2
(Thermus
thermophilus) 		4 / 7 ILE A 152
LEU A 169
ARG A 147
LEU A 118
 None
 0.88A 5xdqA-4j80A:
undetectable
5xdqJ-4j80A:
undetectable		 5xdqA-4j80A:
18.79
5xdqJ-4j80A:
10.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4j80 CHAPERONE PROTEIN
DNAJ 2
(Thermus
thermophilus) 		4 / 7 ILE A 152
LEU A 169
ARG A 147
LEU A 118
 None
 0.92A 5zcqA-4j80A:
undetectable
5zcqJ-4j80A:
undetectable		 5zcqA-4j80A:
18.79
5zcqJ-4j80A:
10.92