SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4j8c'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D1V_A_H4BA700_1
(BOVINE ENDOTHELIAL
NITRIC OXIDE
SYNTHASE HEME)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 VAL A  35
TRP A  34
PHE A  30
GLU A  36
None
1.47A 1d1vA-4j8cA:
undetectable
1d1vB-4j8cA:
undetectable
1d1vA-4j8cA:
8.43
1d1vB-4j8cA:
8.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D1X_A_H4BA600_1
(BOVINE ENDOTHELIAL
NITRIC OXIDE
SYNTHASE HEME DOMAIN)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 VAL A  35
TRP A  34
PHE A  30
GLU A  36
None
1.49A 1d1xA-4j8cA:
undetectable
1d1xB-4j8cA:
undetectable
1d1xA-4j8cA:
8.43
1d1xB-4j8cA:
8.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DM8_A_H4BA1600_1
(NITRIC OXIDE
SYNTHASE)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 VAL A  35
TRP A  34
PHE A  30
GLU A  36
None
1.50A 1dm8A-4j8cA:
undetectable
1dm8B-4j8cA:
undetectable
1dm8A-4j8cA:
8.43
1dm8B-4j8cA:
8.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOP_A_H4BA1600_1
(NITRIC-OXIDE
SYNTHASE)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 VAL A  35
TRP A  34
PHE A  30
GLU A  36
None
1.47A 1fopA-4j8cA:
undetectable
1fopB-4j8cA:
undetectable
1fopA-4j8cA:
8.43
1fopB-4j8cA:
8.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSE_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 VAL A  35
TRP A  34
PHE A  30
GLU A  36
None
1.47A 1nseA-4j8cA:
undetectable
1nseB-4j8cA:
undetectable
1nseA-4j8cA:
8.43
1nseB-4j8cA:
8.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSE_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 PHE A  30
GLU A  36
VAL A  35
TRP A  34
None
1.50A 1nseA-4j8cA:
undetectable
1nseB-4j8cA:
undetectable
1nseA-4j8cA:
8.43
1nseB-4j8cA:
8.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6L_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 VAL A  35
TRP A  34
PHE A  30
GLU A  36
None
1.48A 1p6lA-4j8cA:
undetectable
1p6lB-4j8cA:
undetectable
1p6lA-4j8cA:
8.01
1p6lB-4j8cA:
8.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6L_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 PHE A  30
GLU A  36
VAL A  35
TRP A  34
None
1.48A 1p6lA-4j8cA:
undetectable
1p6lB-4j8cA:
undetectable
1p6lA-4j8cA:
8.01
1p6lB-4j8cA:
8.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6N_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 PHE A  30
GLU A  36
VAL A  35
TRP A  34
None
1.49A 1p6nA-4j8cA:
undetectable
1p6nB-4j8cA:
undetectable
1p6nA-4j8cA:
8.01
1p6nB-4j8cA:
8.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q2O_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 VAL A  35
TRP A  34
PHE A  30
GLU A  36
None
1.49A 1q2oA-4j8cA:
undetectable
1q2oB-4j8cA:
undetectable
1q2oA-4j8cA:
8.01
1q2oB-4j8cA:
8.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS8_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 VAL A  35
TRP A  34
PHE A  30
GLU A  36
None
1.50A 1rs8A-4j8cA:
undetectable
1rs8B-4j8cA:
undetectable
1rs8A-4j8cA:
8.01
1rs8B-4j8cA:
8.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS9_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 PHE A  30
GLU A  36
VAL A  35
TRP A  34
None
1.46A 1rs9A-4j8cA:
undetectable
1rs9B-4j8cA:
undetectable
1rs9A-4j8cA:
8.01
1rs9B-4j8cA:
8.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZS_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 VAL A  35
TRP A  34
PHE A  30
GLU A  36
None
1.48A 1zzsA-4j8cA:
undetectable
1zzsB-4j8cA:
undetectable
1zzsA-4j8cA:
8.01
1zzsB-4j8cA:
8.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZS_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 PHE A  30
GLU A  36
VAL A  35
TRP A  34
None
1.48A 1zzsA-4j8cA:
undetectable
1zzsB-4j8cA:
undetectable
1zzsA-4j8cA:
8.01
1zzsB-4j8cA:
8.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX2_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 VAL A  35
TRP A  34
PHE A  30
GLU A  36
None
1.50A 2hx2A-4j8cA:
undetectable
2hx2B-4j8cA:
undetectable
2hx2A-4j8cA:
8.01
2hx2B-4j8cA:
8.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX2_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 PHE A  30
GLU A  36
VAL A  35
TRP A  34
None
1.49A 2hx2A-4j8cA:
undetectable
2hx2B-4j8cA:
undetectable
2hx2A-4j8cA:
8.01
2hx2B-4j8cA:
8.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSE_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 VAL A  35
TRP A  34
PHE A  30
GLU A  36
None
1.49A 2nseA-4j8cA:
undetectable
2nseB-4j8cA:
undetectable
2nseA-4j8cA:
8.43
2nseB-4j8cA:
8.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQS_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 VAL A  35
TRP A  34
PHE A  30
GLU A  36
None
1.49A 3dqsA-4j8cA:
undetectable
3dqsB-4j8cA:
undetectable
3dqsA-4j8cA:
8.01
3dqsB-4j8cA:
8.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWX_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 PHE A  30
GLU A  36
VAL A  35
TRP A  34
None
1.47A 3jwxA-4j8cA:
undetectable
3jwxB-4j8cA:
undetectable
3jwxA-4j8cA:
8.43
3jwxB-4j8cA:
8.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWZ_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 VAL A  35
TRP A  34
PHE A  30
GLU A  36
None
1.49A 3jwzA-4j8cA:
undetectable
3jwzB-4j8cA:
undetectable
3jwzA-4j8cA:
8.43
3jwzB-4j8cA:
8.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWZ_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 PHE A  30
GLU A  36
VAL A  35
TRP A  34
None
1.49A 3jwzA-4j8cA:
undetectable
3jwzB-4j8cA:
undetectable
3jwzA-4j8cA:
8.43
3jwzB-4j8cA:
8.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Q_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 VAL A  35
TRP A  34
PHE A  30
GLU A  36
None
1.45A 3n5qA-4j8cA:
undetectable
3n5qB-4j8cA:
undetectable
3n5qA-4j8cA:
8.43
3n5qB-4j8cA:
8.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5R_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 VAL A  35
TRP A  34
PHE A  30
GLU A  36
None
1.47A 3n5rA-4j8cA:
undetectable
3n5rB-4j8cA:
undetectable
3n5rA-4j8cA:
8.43
3n5rB-4j8cA:
8.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5R_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 PHE A  30
GLU A  36
VAL A  35
TRP A  34
None
1.47A 3n5rA-4j8cA:
undetectable
3n5rB-4j8cA:
undetectable
3n5rA-4j8cA:
8.43
3n5rB-4j8cA:
8.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5S_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 VAL A  35
TRP A  34
PHE A  30
GLU A  36
None
1.50A 3n5sA-4j8cA:
undetectable
3n5sB-4j8cA:
undetectable
3n5sA-4j8cA:
8.43
3n5sB-4j8cA:
8.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5S_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 PHE A  30
GLU A  36
VAL A  35
TRP A  34
None
1.48A 3n5sA-4j8cA:
undetectable
3n5sB-4j8cA:
undetectable
3n5sA-4j8cA:
8.43
3n5sB-4j8cA:
8.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5T_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 PHE A  30
GLU A  36
VAL A  35
TRP A  34
None
1.48A 3n5tA-4j8cA:
undetectable
3n5tB-4j8cA:
undetectable
3n5tA-4j8cA:
8.43
3n5tB-4j8cA:
8.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6E_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 VAL A  35
TRP A  34
PHE A  30
GLU A  36
None
1.47A 3n6eA-4j8cA:
undetectable
3n6eB-4j8cA:
undetectable
3n6eA-4j8cA:
8.43
3n6eB-4j8cA:
8.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6E_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 PHE A  30
GLU A  36
VAL A  35
TRP A  34
None
1.49A 3n6eA-4j8cA:
undetectable
3n6eB-4j8cA:
undetectable
3n6eA-4j8cA:
8.43
3n6eB-4j8cA:
8.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6F_A_H4BA600_1
('NITRIC OXIDE
SYNTHASE)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 VAL A  35
TRP A  34
PHE A  30
GLU A  36
None
1.48A 3n6fA-4j8cA:
undetectable
3n6fB-4j8cA:
undetectable
3n6fA-4j8cA:
8.43
3n6fB-4j8cA:
8.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6F_B_H4BB600_1
('NITRIC OXIDE
SYNTHASE)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 PHE A  30
GLU A  36
VAL A  35
TRP A  34
None
1.47A 3n6fA-4j8cA:
undetectable
3n6fB-4j8cA:
undetectable
3n6fA-4j8cA:
8.43
3n6fB-4j8cA:
8.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6G_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 VAL A  35
TRP A  34
PHE A  30
GLU A  36
None
1.49A 3n6gA-4j8cA:
undetectable
3n6gB-4j8cA:
undetectable
3n6gA-4j8cA:
8.43
3n6gB-4j8cA:
8.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6G_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 PHE A  30
GLU A  36
VAL A  35
TRP A  34
None
1.48A 3n6gA-4j8cA:
undetectable
3n6gB-4j8cA:
undetectable
3n6gA-4j8cA:
8.43
3n6gB-4j8cA:
8.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLE_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 VAL A  35
TRP A  34
PHE A  30
GLU A  36
None
1.49A 3nleA-4j8cA:
undetectable
3nleB-4j8cA:
undetectable
3nleA-4j8cA:
8.43
3nleB-4j8cA:
8.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLE_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 PHE A  30
GLU A  36
VAL A  35
TRP A  34
None
1.47A 3nleA-4j8cA:
undetectable
3nleB-4j8cA:
undetectable
3nleA-4j8cA:
8.43
3nleB-4j8cA:
8.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLG_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 VAL A  35
TRP A  34
PHE A  30
GLU A  36
None
1.48A 3nlgA-4j8cA:
undetectable
3nlgB-4j8cA:
undetectable
3nlgA-4j8cA:
8.43
3nlgB-4j8cA:
8.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLI_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 VAL A  35
TRP A  34
PHE A  30
GLU A  36
None
1.49A 3nliA-4j8cA:
undetectable
3nliB-4j8cA:
undetectable
3nliA-4j8cA:
8.43
3nliB-4j8cA:
8.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLI_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 PHE A  30
GLU A  36
VAL A  35
TRP A  34
None
1.48A 3nliA-4j8cA:
undetectable
3nliB-4j8cA:
undetectable
3nliA-4j8cA:
8.43
3nliB-4j8cA:
8.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLU_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 VAL A  35
TRP A  34
PHE A  30
GLU A  36
None
1.46A 3nluA-4j8cA:
undetectable
3nluB-4j8cA:
undetectable
3nluA-4j8cA:
8.43
3nluB-4j8cA:
8.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NOS_A_H4BA511_1
(ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 VAL A  35
TRP A  34
PHE A  30
GLU A  36
None
1.49A 3nosA-4j8cA:
undetectable
3nosB-4j8cA:
undetectable
3nosA-4j8cA:
9.07
3nosB-4j8cA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NOS_B_H4BB1011_1
(ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 PHE A  30
GLU A  36
VAL A  35
TRP A  34
None
1.46A 3nosA-4j8cA:
undetectable
3nosB-4j8cA:
undetectable
3nosA-4j8cA:
9.07
3nosB-4j8cA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNH_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 VAL A  35
TRP A  34
PHE A  30
GLU A  36
None
1.47A 3pnhA-4j8cA:
undetectable
3pnhB-4j8cA:
undetectable
3pnhA-4j8cA:
8.01
3pnhB-4j8cA:
8.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNH_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 PHE A  30
GLU A  36
VAL A  35
TRP A  34
None
1.47A 3pnhA-4j8cA:
undetectable
3pnhB-4j8cA:
undetectable
3pnhA-4j8cA:
8.01
3pnhB-4j8cA:
8.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQO_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 VAL A  35
TRP A  34
PHE A  30
GLU A  36
None
1.47A 3rqoA-4j8cA:
undetectable
3rqoB-4j8cA:
undetectable
3rqoA-4j8cA:
8.45
3rqoB-4j8cA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQO_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 PHE A  30
GLU A  36
VAL A  35
TRP A  34
None
1.49A 3rqoA-4j8cA:
undetectable
3rqoB-4j8cA:
undetectable
3rqoA-4j8cA:
8.45
3rqoB-4j8cA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C3A_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 VAL A  35
TRP A  34
PHE A  30
GLU A  36
None
1.47A 4c3aA-4j8cA:
undetectable
4c3aB-4j8cA:
undetectable
4c3aA-4j8cA:
8.45
4c3aB-4j8cA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAR_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 VAL A  35
TRP A  34
PHE A  30
GLU A  36
None
1.49A 4carA-4j8cA:
undetectable
4carB-4j8cA:
undetectable
4carA-4j8cA:
8.45
4carB-4j8cA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CFT_A_H4BA600_1
(ENDOTHELIAL NITRIC
OXIDE SYNTHASE)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 VAL A  35
TRP A  34
PHE A  30
GLU A  36
None
1.49A 4cftA-4j8cA:
undetectable
4cftB-4j8cA:
undetectable
4cftA-4j8cA:
8.45
4cftB-4j8cA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CFT_B_H4BB600_1
(ENDOTHELIAL NITRIC
OXIDE SYNTHASE)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 PHE A  30
GLU A  36
VAL A  35
TRP A  34
None
1.49A 4cftA-4j8cA:
undetectable
4cftB-4j8cA:
undetectable
4cftA-4j8cA:
8.45
4cftB-4j8cA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTY_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 VAL A  35
TRP A  34
PHE A  30
GLU A  36
None
1.48A 4ctyA-4j8cA:
undetectable
4ctyB-4j8cA:
undetectable
4ctyA-4j8cA:
8.45
4ctyB-4j8cA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTY_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 PHE A  30
GLU A  36
VAL A  35
TRP A  34
None
1.50A 4ctyA-4j8cA:
undetectable
4ctyB-4j8cA:
undetectable
4ctyA-4j8cA:
8.45
4ctyB-4j8cA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTZ_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 VAL A  35
TRP A  34
PHE A  30
GLU A  36
None
1.49A 4ctzA-4j8cA:
undetectable
4ctzB-4j8cA:
undetectable
4ctzA-4j8cA:
8.45
4ctzB-4j8cA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTZ_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 PHE A  30
GLU A  36
VAL A  35
TRP A  34
None
1.49A 4ctzA-4j8cA:
undetectable
4ctzB-4j8cA:
undetectable
4ctzA-4j8cA:
8.45
4ctzB-4j8cA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CU0_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 VAL A  35
TRP A  34
PHE A  30
GLU A  36
None
1.46A 4cu0A-4j8cA:
undetectable
4cu0B-4j8cA:
undetectable
4cu0A-4j8cA:
8.45
4cu0B-4j8cA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CU0_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 PHE A  30
GLU A  36
VAL A  35
TRP A  34
None
1.47A 4cu0A-4j8cA:
undetectable
4cu0B-4j8cA:
undetectable
4cu0A-4j8cA:
8.45
4cu0B-4j8cA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CU1_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 VAL A  35
TRP A  34
PHE A  30
GLU A  36
None
1.49A 4cu1A-4j8cA:
undetectable
4cu1B-4j8cA:
undetectable
4cu1A-4j8cA:
8.45
4cu1B-4j8cA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CU1_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 PHE A  30
GLU A  36
VAL A  35
TRP A  34
None
1.49A 4cu1A-4j8cA:
undetectable
4cu1B-4j8cA:
undetectable
4cu1A-4j8cA:
8.45
4cu1B-4j8cA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWV_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 VAL A  35
TRP A  34
PHE A  30
GLU A  36
None
1.47A 4cwvA-4j8cA:
undetectable
4cwvB-4j8cA:
undetectable
4cwvA-4j8cA:
8.45
4cwvB-4j8cA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWW_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 VAL A  35
TRP A  34
PHE A  30
GLU A  36
None
1.45A 4cwwA-4j8cA:
undetectable
4cwwB-4j8cA:
undetectable
4cwwA-4j8cA:
8.45
4cwwB-4j8cA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWW_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 PHE A  30
GLU A  36
VAL A  35
TRP A  34
None
1.46A 4cwwA-4j8cA:
undetectable
4cwwB-4j8cA:
undetectable
4cwwA-4j8cA:
8.45
4cwwB-4j8cA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWX_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 VAL A  35
TRP A  34
PHE A  30
GLU A  36
None
1.46A 4cwxA-4j8cA:
undetectable
4cwxB-4j8cA:
undetectable
4cwxA-4j8cA:
8.45
4cwxB-4j8cA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWX_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 7 PHE A  30
GLU A  36
VAL A  35
TRP A  34
None
1.48A 4cwxA-4j8cA:
undetectable
4cwxB-4j8cA:
undetectable
4cwxA-4j8cA:
8.45
4cwxB-4j8cA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWY_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 7 VAL A  35
TRP A  34
PHE A  30
GLU A  36
None
1.47A 4cwyA-4j8cA:
undetectable
4cwyB-4j8cA:
undetectable
4cwyA-4j8cA:
8.45
4cwyB-4j8cA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWY_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 7 PHE A  30
GLU A  36
VAL A  35
TRP A  34
None
1.48A 4cwyA-4j8cA:
undetectable
4cwyB-4j8cA:
undetectable
4cwyA-4j8cA:
8.45
4cwyB-4j8cA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWZ_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 VAL A  35
TRP A  34
PHE A  30
GLU A  36
None
1.47A 4cwzA-4j8cA:
undetectable
4cwzB-4j8cA:
undetectable
4cwzA-4j8cA:
8.45
4cwzB-4j8cA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWZ_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 PHE A  30
GLU A  36
VAL A  35
TRP A  34
None
1.44A 4cwzA-4j8cA:
undetectable
4cwzB-4j8cA:
undetectable
4cwzA-4j8cA:
8.45
4cwzB-4j8cA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX0_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 VAL A  35
TRP A  34
PHE A  30
GLU A  36
None
1.49A 4cx0A-4j8cA:
undetectable
4cx0B-4j8cA:
undetectable
4cx0A-4j8cA:
8.45
4cx0B-4j8cA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX0_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 PHE A  30
GLU A  36
VAL A  35
TRP A  34
None
1.49A 4cx0A-4j8cA:
undetectable
4cx0B-4j8cA:
undetectable
4cx0A-4j8cA:
8.45
4cx0B-4j8cA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1P_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 PHE A  30
GLU A  36
VAL A  35
TRP A  34
None
1.50A 4d1pA-4j8cA:
undetectable
4d1pB-4j8cA:
undetectable
4d1pA-4j8cA:
8.79
4d1pB-4j8cA:
8.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D36_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 VAL A  35
TRP A  34
PHE A  30
GLU A  36
None
1.48A 4d36A-4j8cA:
undetectable
4d36B-4j8cA:
undetectable
4d36A-4j8cA:
8.45
4d36B-4j8cA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D37_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 VAL A  35
TRP A  34
PHE A  30
GLU A  36
None
1.47A 4d37A-4j8cA:
undetectable
4d37B-4j8cA:
undetectable
4d37A-4j8cA:
8.45
4d37B-4j8cA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D37_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 PHE A  30
GLU A  36
VAL A  35
TRP A  34
None
1.48A 4d37A-4j8cA:
undetectable
4d37B-4j8cA:
undetectable
4d37A-4j8cA:
8.45
4d37B-4j8cA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D38_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 VAL A  35
TRP A  34
PHE A  30
GLU A  36
None
1.49A 4d38A-4j8cA:
undetectable
4d38B-4j8cA:
undetectable
4d38A-4j8cA:
8.45
4d38B-4j8cA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMX_A_H4BA502_1
(SUBUNIT A)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 VAL A  35
TRP A  34
PHE A  30
GLU A  36
None
1.48A 4imxA-4j8cA:
undetectable
4imxB-4j8cA:
undetectable
4imxA-4j8cA:
8.47
4imxB-4j8cA:
8.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMX_B_H4BB502_1
(SUBUNIT A)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 PHE A  30
GLU A  36
VAL A  35
TRP A  34
None
1.49A 4imxA-4j8cA:
undetectable
4imxB-4j8cA:
undetectable
4imxA-4j8cA:
8.47
4imxB-4j8cA:
8.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSK_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 PHE A  30
GLU A  36
VAL A  35
TRP A  34
None
1.48A 4jskA-4j8cA:
undetectable
4jskB-4j8cA:
undetectable
4jskA-4j8cA:
8.45
4jskB-4j8cA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSL_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 VAL A  35
TRP A  34
PHE A  30
GLU A  36
None
1.49A 4jslA-4j8cA:
undetectable
4jslB-4j8cA:
undetectable
4jslA-4j8cA:
8.45
4jslB-4j8cA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSL_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 PHE A  30
GLU A  36
VAL A  35
TRP A  34
None
1.49A 4jslA-4j8cA:
undetectable
4jslB-4j8cA:
undetectable
4jslA-4j8cA:
8.45
4jslB-4j8cA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSM_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 VAL A  35
TRP A  34
PHE A  30
GLU A  36
None
1.49A 4jsmA-4j8cA:
undetectable
4jsmB-4j8cA:
undetectable
4jsmA-4j8cA:
8.45
4jsmB-4j8cA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSM_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 PHE A  30
GLU A  36
VAL A  35
TRP A  34
None
1.47A 4jsmA-4j8cA:
undetectable
4jsmB-4j8cA:
undetectable
4jsmA-4j8cA:
8.45
4jsmB-4j8cA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5H_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 PHE A  30
GLU A  36
VAL A  35
TRP A  34
None
1.50A 4k5hA-4j8cA:
undetectable
4k5hB-4j8cA:
undetectable
4k5hA-4j8cA:
8.45
4k5hB-4j8cA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5I_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 VAL A  35
TRP A  34
PHE A  30
GLU A  36
None
1.48A 4k5iA-4j8cA:
undetectable
4k5iB-4j8cA:
undetectable
4k5iA-4j8cA:
8.45
4k5iB-4j8cA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5J_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 VAL A  35
TRP A  34
PHE A  30
GLU A  36
None
1.50A 4k5jA-4j8cA:
undetectable
4k5jB-4j8cA:
undetectable
4k5jA-4j8cA:
8.45
4k5jB-4j8cA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCP_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 VAL A  35
TRP A  34
PHE A  30
GLU A  36
None
1.46A 4kcpA-4j8cA:
undetectable
4kcpB-4j8cA:
undetectable
4kcpA-4j8cA:
8.45
4kcpB-4j8cA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCP_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 PHE A  30
GLU A  36
VAL A  35
TRP A  34
None
1.48A 4kcpA-4j8cA:
undetectable
4kcpB-4j8cA:
undetectable
4kcpA-4j8cA:
8.45
4kcpB-4j8cA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCQ_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 VAL A  35
TRP A  34
PHE A  30
GLU A  36
None
1.46A 4kcqA-4j8cA:
undetectable
4kcqB-4j8cA:
undetectable
4kcqA-4j8cA:
8.45
4kcqB-4j8cA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCQ_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 PHE A  30
GLU A  36
VAL A  35
TRP A  34
None
1.49A 4kcqA-4j8cA:
undetectable
4kcqB-4j8cA:
undetectable
4kcqA-4j8cA:
8.45
4kcqB-4j8cA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCR_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 VAL A  35
TRP A  34
PHE A  30
GLU A  36
None
1.48A 4kcrA-4j8cA:
undetectable
4kcrB-4j8cA:
undetectable
4kcrA-4j8cA:
8.45
4kcrB-4j8cA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCS_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 VAL A  35
TRP A  34
PHE A  30
GLU A  36
None
1.47A 4kcsA-4j8cA:
undetectable
4kcsB-4j8cA:
undetectable
4kcsA-4j8cA:
8.45
4kcsB-4j8cA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCS_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 PHE A  30
GLU A  36
VAL A  35
TRP A  34
None
1.47A 4kcsA-4j8cA:
undetectable
4kcsB-4j8cA:
undetectable
4kcsA-4j8cA:
8.45
4kcsB-4j8cA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUW_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 VAL A  35
TRP A  34
PHE A  30
GLU A  36
None
1.48A 4luwA-4j8cA:
undetectable
4luwB-4j8cA:
undetectable
4luwA-4j8cA:
8.47
4luwB-4j8cA:
8.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH7_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 VAL A  35
TRP A  34
PHE A  30
GLU A  36
None
1.48A 4uh7A-4j8cA:
undetectable
4uh7B-4j8cA:
undetectable
4uh7A-4j8cA:
8.45
4uh7B-4j8cA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH8_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 VAL A  35
TRP A  34
PHE A  30
GLU A  36
None
1.48A 4uh8A-4j8cA:
undetectable
4uh8B-4j8cA:
undetectable
4uh8A-4j8cA:
8.45
4uh8B-4j8cA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH8_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 PHE A  30
GLU A  36
VAL A  35
TRP A  34
None
1.49A 4uh8A-4j8cA:
undetectable
4uh8B-4j8cA:
undetectable
4uh8A-4j8cA:
8.45
4uh8B-4j8cA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH9_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 VAL A  35
TRP A  34
PHE A  30
GLU A  36
None
1.46A 4uh9A-4j8cA:
undetectable
4uh9B-4j8cA:
undetectable
4uh9A-4j8cA:
8.45
4uh9B-4j8cA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH9_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 PHE A  30
GLU A  36
VAL A  35
TRP A  34
None
1.50A 4uh9A-4j8cA:
undetectable
4uh9B-4j8cA:
undetectable
4uh9A-4j8cA:
8.45
4uh9B-4j8cA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UHA_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 VAL A  35
TRP A  34
PHE A  30
GLU A  36
None
1.49A 4uhaA-4j8cA:
undetectable
4uhaB-4j8cA:
undetectable
4uhaA-4j8cA:
8.45
4uhaB-4j8cA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPQ_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 VAL A  35
TRP A  34
PHE A  30
GLU A  36
None
1.48A 4upqA-4j8cA:
undetectable
4upqB-4j8cA:
undetectable
4upqA-4j8cA:
8.45
4upqB-4j8cA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPQ_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 PHE A  30
GLU A  36
VAL A  35
TRP A  34
None
1.48A 4upqA-4j8cA:
undetectable
4upqB-4j8cA:
undetectable
4upqA-4j8cA:
8.45
4upqB-4j8cA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPR_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 VAL A  35
TRP A  34
PHE A  30
GLU A  36
None
1.47A 4uprA-4j8cA:
undetectable
4uprB-4j8cA:
undetectable
4uprA-4j8cA:
8.45
4uprB-4j8cA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPR_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 PHE A  30
GLU A  36
VAL A  35
TRP A  34
None
1.48A 4uprA-4j8cA:
undetectable
4uprB-4j8cA:
undetectable
4uprA-4j8cA:
8.45
4uprB-4j8cA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPS_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 VAL A  35
TRP A  34
PHE A  30
GLU A  36
None
1.49A 4upsA-4j8cA:
undetectable
4upsB-4j8cA:
undetectable
4upsA-4j8cA:
8.45
4upsB-4j8cA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPS_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 PHE A  30
GLU A  36
VAL A  35
TRP A  34
None
1.46A 4upsA-4j8cA:
undetectable
4upsB-4j8cA:
undetectable
4upsA-4j8cA:
8.45
4upsB-4j8cA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPT_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 VAL A  35
TRP A  34
PHE A  30
GLU A  36
None
1.49A 4uptA-4j8cA:
undetectable
4uptB-4j8cA:
undetectable
4uptA-4j8cA:
8.45
4uptB-4j8cA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADJ_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 VAL A  35
TRP A  34
PHE A  30
GLU A  36
None
1.48A 5adjA-4j8cA:
undetectable
5adjB-4j8cA:
undetectable
5adjA-4j8cA:
8.45
5adjB-4j8cA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADK_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 VAL A  35
TRP A  34
PHE A  30
GLU A  36
None
1.48A 5adkA-4j8cA:
undetectable
5adkB-4j8cA:
undetectable
5adkA-4j8cA:
8.45
5adkB-4j8cA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADK_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 PHE A  30
GLU A  36
VAL A  35
TRP A  34
None
1.50A 5adkA-4j8cA:
undetectable
5adkB-4j8cA:
undetectable
5adkA-4j8cA:
8.45
5adkB-4j8cA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADL_A_H4BA600_1
(ENDOTHELIAL NITRIC
OXIDE SYNTHASE)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 VAL A  35
TRP A  34
PHE A  30
GLU A  36
None
1.48A 5adlA-4j8cA:
undetectable
5adlB-4j8cA:
undetectable
5adlA-4j8cA:
8.45
5adlB-4j8cA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADM_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 VAL A  35
TRP A  34
PHE A  30
GLU A  36
None
1.48A 5admA-4j8cA:
undetectable
5admB-4j8cA:
undetectable
5admA-4j8cA:
8.45
5admB-4j8cA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADM_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 PHE A  30
GLU A  36
VAL A  35
TRP A  34
None
1.48A 5admA-4j8cA:
undetectable
5admB-4j8cA:
undetectable
5admA-4j8cA:
8.45
5admB-4j8cA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADN_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 VAL A  35
TRP A  34
PHE A  30
GLU A  36
None
1.49A 5adnA-4j8cA:
undetectable
5adnB-4j8cA:
undetectable
5adnA-4j8cA:
8.45
5adnB-4j8cA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FJ2_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 VAL A  35
TRP A  34
PHE A  30
GLU A  36
None
1.50A 5fj2A-4j8cA:
undetectable
5fj2B-4j8cA:
undetectable
5fj2A-4j8cA:
8.45
5fj2B-4j8cA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FJ2_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 PHE A  30
GLU A  36
VAL A  35
TRP A  34
None
1.49A 5fj2A-4j8cA:
undetectable
5fj2B-4j8cA:
undetectable
5fj2A-4j8cA:
8.45
5fj2B-4j8cA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVZ_A_H4BA600_1
(ENDOTHELIAL NITRIC
OXIDE SYNTHASE)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 VAL A  35
TRP A  34
PHE A  30
GLU A  36
None
1.48A 5fvzA-4j8cA:
undetectable
5fvzB-4j8cA:
undetectable
5fvzA-4j8cA:
8.45
5fvzB-4j8cA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO8_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 PHE A  30
GLU A  36
VAL A  35
TRP A  34
None
1.43A 5uo8A-4j8cA:
undetectable
5uo8B-4j8cA:
undetectable
5uo8A-4j8cA:
8.79
5uo8B-4j8cA:
8.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UOD_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 VAL A  35
TRP A  34
PHE A  30
GLU A  36
None
1.49A 5uodA-4j8cA:
undetectable
5uodB-4j8cA:
undetectable
5uodA-4j8cA:
8.45
5uodB-4j8cA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UOD_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 PHE A  30
GLU A  36
VAL A  35
TRP A  34
None
1.49A 5uodA-4j8cA:
undetectable
5uodB-4j8cA:
undetectable
5uodA-4j8cA:
8.45
5uodB-4j8cA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV6_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 VAL A  35
TRP A  34
PHE A  30
GLU A  36
None
1.47A 5vv6A-4j8cA:
undetectable
5vv6B-4j8cA:
undetectable
5vv6A-4j8cA:
8.45
5vv6B-4j8cA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV6_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 PHE A  30
GLU A  36
VAL A  35
TRP A  34
None
1.48A 5vv6A-4j8cA:
undetectable
5vv6B-4j8cA:
undetectable
5vv6A-4j8cA:
8.45
5vv6B-4j8cA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV7_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 VAL A  35
TRP A  34
PHE A  30
GLU A  36
None
1.48A 5vv7A-4j8cA:
undetectable
5vv7B-4j8cA:
undetectable
5vv7A-4j8cA:
8.45
5vv7B-4j8cA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV8_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 VAL A  35
TRP A  34
PHE A  30
GLU A  36
None
1.47A 5vv8A-4j8cA:
undetectable
5vv8B-4j8cA:
undetectable
5vv8A-4j8cA:
8.45
5vv8B-4j8cA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV9_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 7 VAL A  35
TRP A  34
PHE A  30
GLU A  36
None
1.46A 5vv9A-4j8cA:
undetectable
5vv9B-4j8cA:
undetectable
5vv9A-4j8cA:
8.45
5vv9B-4j8cA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVD_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 7 PHE A  30
GLU A  36
VAL A  35
TRP A  34
None
1.47A 5vvdA-4j8cA:
undetectable
5vvdB-4j8cA:
undetectable
5vvdA-4j8cA:
8.79
5vvdB-4j8cA:
8.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
9NSE_A_H4BA600_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))
4j8c HSC70-INTERACTING
PROTEIN

(Rattus
norvegicus)
4 / 6 VAL A  35
TRP A  34
PHE A  30
GLU A  36
None
1.48A 9nseA-4j8cA:
undetectable
9nseB-4j8cA:
undetectable
9nseA-4j8cA:
8.43
9nseB-4j8cA:
8.43