SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4j8q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3C6G_A_VD3A701_2 (CYTOCHROME P450 2R1)	4j8q	PUTATIVE UNCHARACTERIZED PROTEIN (Bacteroides fragilis)	3 / 3	MET A 159 VAL A 107 GLU A 175	None	0.74A	3c6gA-4j8qA: undetectable	3c6gA-4j8qA: 20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3E68_A_H4BA902_1 (NITRIC OXIDE SYNTHASE, INDUCIBLE)	4j8q	PUTATIVE UNCHARACTERIZED PROTEIN (Bacteroides fragilis)	3 / 3	ARG A 75 ILE A 132 TRP A 131	None	1.17A	3e68A-4j8qA: undetectable	3e68A-4j8qA: 17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4JKU_B_ADNB500_1 (PROBABLE SUGAR KINASE PROTEIN)	4j8q	PUTATIVE UNCHARACTERIZED PROTEIN (Bacteroides fragilis)	5 / 12	ASN A 196 ASP A 53 GLY A 133 GLY A 135 THR A 39	None	1.09A	4jkuB-4j8qA: undetectable	4jkuB-4j8qA: 22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K93_A_ADNA401_1 (SUGAR KINASE)	4j8q	PUTATIVE UNCHARACTERIZED PROTEIN (Bacteroides fragilis)	5 / 12	ASN A 196 ASP A 53 GLY A 133 GLY A 135 THR A 39	None	1.09A	4k93A-4j8qA: undetectable	4k93A-4j8qA: 22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K9C_B_ADNB401_1 (SUGAR KINASE)	4j8q	PUTATIVE UNCHARACTERIZED PROTEIN (Bacteroides fragilis)	5 / 12	ASN A 196 ASP A 53 GLY A 133 GLY A 135 THR A 39	None	1.10A	4k9cB-4j8qA: undetectable	4k9cB-4j8qA: 22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K9I_A_ADNA401_1 (SUGAR KINASE)	4j8q	PUTATIVE UNCHARACTERIZED PROTEIN (Bacteroides fragilis)	5 / 12	ASN A 196 ASP A 53 GLY A 133 GLY A 135 THR A 39	None	1.10A	4k9iA-4j8qA: undetectable	4k9iA-4j8qA: 22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KAD_B_ADNB401_1 (PROBABLE SUGAR KINASE PROTEIN)	4j8q	PUTATIVE UNCHARACTERIZED PROTEIN (Bacteroides fragilis)	5 / 12	ASN A 196 ASP A 53 GLY A 133 GLY A 135 THR A 39	None	1.10A	4kadB-4j8qA: undetectable	4kadB-4j8qA: 22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WNW_A_RTZA602_1 (CYTOCHROME P450 2D6)	4j8q	PUTATIVE UNCHARACTERIZED PROTEIN (Bacteroides fragilis)	5 / 12	LEU A 137 ASP A 128 VAL A 210 VAL A 153 PHE A 195	None None None EDO A 300 (-4.3A) None	1.18A	4wnwA-4j8qA: undetectable	4wnwA-4j8qA: 20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TZO_A_7V7A202_1 (ENDO-1,4-BETA-XYLANA SE A)	4j8q	PUTATIVE UNCHARACTERIZED PROTEIN (Bacteroides fragilis)	5 / 12	VAL A 76 TRP A 55 ALA A 52 TYR A 68 ALA A 38	None	1.36A	5tzoA-4j8qA: undetectable	5tzoA-4j8qA: 22.27

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3C6G_A_VD3A701_2","CYTOCHROME P450 2R1","4j8q","PUTATIVE UNCHARACTERIZED PROTEIN","Bacteroides fragilis",3,"MET A 159;VAL A 107;GLU A 175","None","0.74A","3c6gA-4j8qA:undetectable","3c6gA-4j8qA:20.17"],["3E68_A_H4BA902_1","NITRIC OXIDE SYNTHASE, INDUCIBLE","4j8q","PUTATIVE UNCHARACTERIZED PROTEIN","Bacteroides fragilis",3,"ARG A  75;ILE A 132;TRP A 131","None","1.17A","3e68A-4j8qA:undetectable","3e68A-4j8qA:17.51"],["4JKU_B_ADNB500_1","PROBABLE SUGAR KINASE PROTEIN","4j8q","PUTATIVE UNCHARACTERIZED PROTEIN","Bacteroides fragilis",5,"ASN A 196;ASP A  53;GLY A 133;GLY A 135;THR A  39","None","1.09A","4jkuB-4j8qA:undetectable","4jkuB-4j8qA:22.04"],["4K93_A_ADNA401_1","SUGAR KINASE","4j8q","PUTATIVE UNCHARACTERIZED PROTEIN","Bacteroides fragilis",5,"ASN A 196;ASP A  53;GLY A 133;GLY A 135;THR A  39","None","1.09A","4k93A-4j8qA:undetectable","4k93A-4j8qA:22.04"],["4K9C_B_ADNB401_1","SUGAR KINASE","4j8q","PUTATIVE UNCHARACTERIZED PROTEIN","Bacteroides fragilis",5,"ASN A 196;ASP A  53;GLY A 133;GLY A 135;THR A  39","None","1.10A","4k9cB-4j8qA:undetectable","4k9cB-4j8qA:22.04"],["4K9I_A_ADNA401_1","SUGAR KINASE","4j8q","PUTATIVE UNCHARACTERIZED PROTEIN","Bacteroides fragilis",5,"ASN A 196;ASP A  53;GLY A 133;GLY A 135;THR A  39","None","1.10A","4k9iA-4j8qA:undetectable","4k9iA-4j8qA:22.04"],["4KAD_B_ADNB401_1","PROBABLE SUGAR KINASE PROTEIN","4j8q","PUTATIVE UNCHARACTERIZED PROTEIN","Bacteroides fragilis",5,"ASN A 196;ASP A  53;GLY A 133;GLY A 135;THR A  39","None","1.10A","4kadB-4j8qA:undetectable","4kadB-4j8qA:22.04"],["4WNW_A_RTZA602_1","CYTOCHROME P450 2D6","4j8q","PUTATIVE UNCHARACTERIZED PROTEIN","Bacteroides fragilis",5,"LEU A 137;ASP A 128;VAL A 210;VAL A 153;PHE A 195","None;None;None;EDO A 300 (-4.3A);None","1.18A","4wnwA-4j8qA:undetectable","4wnwA-4j8qA:20.30"],["5TZO_A_7V7A202_1","ENDO-1,4-BETA-XYLANASE A","4j8q","PUTATIVE UNCHARACTERIZED PROTEIN","Bacteroides fragilis",5,"VAL A  76;TRP A  55;ALA A  52;TYR A  68;ALA A  38","None","1.36A","5tzoA-4j8qA:undetectable","5tzoA-4j8qA:22.27"]]