SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4j9u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_B_PFLB4001_1
(SERUM ALBUMIN)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		5 / 9 LEU A  13
ILE A   9
LEU A 145
VAL A 152
GLY A  69
 None
 1.26A 1e7aB-4j9uA:
undetectable		 1e7aB-4j9uA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P91_A_SAMA1401_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE A)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		5 / 11 LEU A 438
GLY A 222
GLY A 113
ILE A 220
LEU A 286
 None
K  A 504 ( 4.5A)
K  A 504 ( 4.6A)
None
None
 1.03A 1p91A-4j9uA:
undetectable		 1p91A-4j9uA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PXX_A_DIFA701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		5 / 10 VAL A  79
GLY A  81
ALA A  83
SER A  85
LEU A  86
 None
 0.73A 1pxxA-4j9uA:
2.3		 1pxxA-4j9uA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PXX_C_DIFC2701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		5 / 12 VAL A  79
GLY A  81
ALA A  83
SER A  85
LEU A  86
 None
 0.72A 1pxxC-4j9uA:
2.2		 1pxxC-4j9uA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_B_URFB2011_1
(URIDINE
PHOSPHORYLASE)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		4 / 8 THR A 352
GLY A 141
ILE A 143
VAL A 144
 None
 0.83A 1rxcB-4j9uA:
undetectable		 1rxcB-4j9uA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_E_URFE2031_1
(URIDINE
PHOSPHORYLASE)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		4 / 8 THR A 352
GLY A 141
ILE A 143
VAL A 144
 None
 0.84A 1rxcE-4j9uA:
undetectable		 1rxcE-4j9uA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_F_URFF2001_1
(URIDINE
PHOSPHORYLASE)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		4 / 7 GLY A 346
GLN A 283
ILE A 361
VAL A 358
 None
 1.01A 1rxcF-4j9uA:
undetectable		 1rxcF-4j9uA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_I_URFI2041_1
(URIDINE
PHOSPHORYLASE)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		4 / 8 THR A 352
GLY A 141
ILE A 143
VAL A 144
 None
 0.90A 1rxcI-4j9uA:
undetectable		 1rxcI-4j9uA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_K_URFK2061_1
(URIDINE
PHOSPHORYLASE)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		4 / 8 THR A 352
GLY A 141
ILE A 143
VAL A 144
 None
 0.86A 1rxcK-4j9uA:
undetectable		 1rxcK-4j9uA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_L_URFL2071_1
(URIDINE
PHOSPHORYLASE)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		4 / 7 GLY A 346
GLN A 283
ILE A 361
VAL A 358
 None
 1.04A 1rxcL-4j9uA:
undetectable		 1rxcL-4j9uA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AKE_A_TRPA479_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		5 / 12 TYR A 406
GLY A 355
GLY A 353
THR A 320
ILE A 471
 None
 1.32A 2akeA-4j9uA:
undetectable		 2akeA-4j9uA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_C_KLNC1498_1
(CYTOCHROME P450 3A4)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		5 / 12 LEU A 442
LEU A 339
PHE A 328
ALA A 321
THR A 319
 None
 1.21A 2v0mC-4j9uA:
undetectable		 2v0mC-4j9uA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VJ1_A_BEZA1303_0
(SARS CORONAVIRUS
MAIN PROTEINASE)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		3 / 3 HIS A 213
MET A 205
MET A 230
 None
 0.93A 2vj1A-4j9uA:
undetectable		 2vj1A-4j9uA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3M_B_FOLB1188_0
(DIHYDROFOLATE
REDUCTASE)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		5 / 12 ALA A  23
PHE A 215
GLN A 135
ARG A 131
THR A  20
 None
 1.25A 2w3mB-4j9uA:
undetectable		 2w3mB-4j9uA:
15.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WD9_C_IBPC1570_1
(ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		5 / 10 THR A 242
ILE A 218
GLY A 353
GLY A 221
THR A 217
 None
None
None
K  A 504 (-3.5A)
None
 1.06A 2wd9C-4j9uA:
undetectable		 2wd9C-4j9uA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WX2_A_TPFA1460_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		4 / 7 ALA A 306
ALA A 310
THR A 314
LEU A 339
 None
 0.90A 2wx2A-4j9uA:
undetectable		 2wx2A-4j9uA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFS_B_J01B600_1
(ORF12)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		5 / 11 ALA A  15
SER A  18
GLY A  50
MET A  52
PHE A  48
 None
 1.49A 2xfsB-4j9uA:
undetectable		 2xfsB-4j9uA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_B_CHDB1086_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 6A2
CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		5 / 11 MET A 356
GLY A 355
THR A 110
THR A 112
PHE A 466
 None
 1.33A 2zxwA-4j9uA:
4.5
2zxwB-4j9uA:
undetectable
2zxwT-4j9uA:
undetectable		 2zxwA-4j9uA:
23.60
2zxwB-4j9uA:
18.89
2zxwT-4j9uA:
10.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_B_CHDB1085_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		5 / 11 MET A 356
GLY A 355
THR A 110
THR A 112
PHE A 466
 None
 1.38A 3abkA-4j9uA:
4.5
3abkB-4j9uA:
undetectable
3abkT-4j9uA:
undetectable		 3abkA-4j9uA:
23.60
3abkB-4j9uA:
18.89
3abkT-4j9uA:
10.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_O_CHDO229_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		5 / 10 PHE A 466
MET A 356
GLY A 355
THR A 110
THR A 112
 None
 1.34A 3abkG-4j9uA:
undetectable
3abkN-4j9uA:
2.5
3abkO-4j9uA:
undetectable		 3abkG-4j9uA:
10.92
3abkN-4j9uA:
23.60
3abkO-4j9uA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_O_CHDO229_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		5 / 11 PHE A 466
MET A 356
GLY A 355
THR A 110
THR A 112
 None
 1.37A 3ag1G-4j9uA:
undetectable
3ag1N-4j9uA:
3.5
3ag1O-4j9uA:
undetectable		 3ag1G-4j9uA:
10.92
3ag1N-4j9uA:
23.60
3ag1O-4j9uA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_B_CHDB1085_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		5 / 11 MET A 356
GLY A 355
THR A 110
THR A 112
PHE A 466
 None
 1.37A 3ag3A-4j9uA:
2.0
3ag3B-4j9uA:
undetectable
3ag3T-4j9uA:
undetectable		 3ag3A-4j9uA:
23.60
3ag3B-4j9uA:
18.89
3ag3T-4j9uA:
10.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_O_CHDO229_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		5 / 11 PHE A 466
MET A 356
GLY A 355
THR A 110
THR A 112
 None
 1.33A 3ag3G-4j9uA:
undetectable
3ag3N-4j9uA:
1.8
3ag3O-4j9uA:
undetectable		 3ag3G-4j9uA:
10.92
3ag3N-4j9uA:
23.60
3ag3O-4j9uA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CR5_X_PNTX95_0
(PROTEIN S100-B)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		3 / 3 CYH A 290
PHE A 291
PHE A 287
 None
 1.07A 3cr5X-4j9uA:
0.3		 3cr5X-4j9uA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELU_A_SAMA4633_0
(METHYLTRANSFERASE)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		5 / 12 GLY A 346
GLY A 354
GLY A 350
THR A 320
ILE A 345
 None
 0.89A 3eluA-4j9uA:
undetectable		 3eluA-4j9uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELW_A_SAMA4633_0
(METHYLTRANSFERASE)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		5 / 12 GLY A 346
GLY A 354
GLY A 350
THR A 320
ILE A 345
 None
 0.90A 3elwA-4j9uA:
undetectable		 3elwA-4j9uA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCR_A_CHDA424_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		4 / 8 LEU A 246
SER A 342
GLY A 439
PRO A 440
 None
 0.85A 3hcrA-4j9uA:
undetectable		 3hcrA-4j9uA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS6_A_EPAA1_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		5 / 12 VAL A  79
GLY A  81
ALA A  83
SER A  85
LEU A  89
 None
 0.73A 3hs6A-4j9uA:
2.9		 3hs6A-4j9uA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I45_A_NIOA500_1
(TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		4 / 8 LEU A  86
TYR A 130
PHE A  17
LEU A  46
 None
 0.99A 3i45A-4j9uA:
undetectable		 3i45A-4j9uA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KHM_A_TPFA501_1
(STEROL 14
ALPHA-DEMETHYLASE)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		4 / 8 ALA A 306
ALA A 310
THR A 314
LEU A 339
 None
 0.79A 3khmA-4j9uA:
undetectable		 3khmA-4j9uA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPC_A_SAMA1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		5 / 11 ASP A 454
VAL A 116
ILE A 117
ASN A  95
ILE A  96
 None
 1.26A 3kpcA-4j9uA:
undetectable		 3kpcA-4j9uA:
12.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L4D_A_TPFA490_1
(STEROL 14-ALPHA
DEMETHYLASE)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		4 / 8 ALA A 306
ALA A 310
THR A 314
LEU A 339
 None
 0.89A 3l4dA-4j9uA:
undetectable		 3l4dA-4j9uA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_A_CELA682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		5 / 12 VAL A  79
GLY A  81
ALA A  83
SER A  85
LEU A  86
 None
 0.76A 3ln1A-4j9uA:
3.4		 3ln1A-4j9uA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_B_CELB682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		5 / 12 VAL A  79
GLY A  81
ALA A  83
SER A  85
LEU A  86
 None
 0.76A 3ln1B-4j9uA:
2.9		 3ln1B-4j9uA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_C_CELC682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		5 / 12 VAL A  79
GLY A  81
ALA A  83
SER A  85
LEU A  86
 None
 0.76A 3ln1C-4j9uA:
2.2		 3ln1C-4j9uA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NT1_A_NPSA5_1
(PROSTAGLANDIN-ENDOPE
ROXIDE SYNTHASE 2)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		5 / 12 VAL A  79
GLY A  81
ALA A  83
SER A  85
LEU A  86
 None
 0.77A 3nt1A-4j9uA:
2.9		 3nt1A-4j9uA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NT1_B_NPSB4_1
(PROSTAGLANDIN-ENDOPE
ROXIDE SYNTHASE 2)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		5 / 12 VAL A  79
GLY A  81
ALA A  83
SER A  85
LEU A  86
 None
 0.75A 3nt1B-4j9uA:
2.0		 3nt1B-4j9uA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_C_FLPC701_1
(CYCLOOXYGENASE-2)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		5 / 12 VAL A  45
GLY A  81
ALA A  83
SER A  85
LEU A  86
 None
 0.95A 3pghC-4j9uA:
2.1		 3pghC-4j9uA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_C_FLPC701_1
(CYCLOOXYGENASE-2)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		5 / 12 VAL A  79
GLY A  81
ALA A  83
SER A  85
LEU A  86
 None
 0.83A 3pghC-4j9uA:
2.1		 3pghC-4j9uA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_D_FLPD701_1
(CYCLOOXYGENASE-2)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		5 / 12 VAL A  79
GLY A  81
ALA A  83
SER A  85
LEU A  86
 None
 0.82A 3pghD-4j9uA:
1.7		 3pghD-4j9uA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PP7_B_SVRB499_1
(PYRUVATE KINASE)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		5 / 10 THR A 434
PRO A 440
ASN A 437
GLY A 221
ALA A 433
 None
None
None
K  A 504 (-3.5A)
None
 1.40A 3pp7B-4j9uA:
undetectable		 3pp7B-4j9uA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RR3_A_FLRA700_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		5 / 12 VAL A  45
GLY A  81
ALA A  83
SER A  85
LEU A  86
 None
 1.02A 3rr3A-4j9uA:
3.2		 3rr3A-4j9uA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RR3_A_FLRA700_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		5 / 12 VAL A  79
GLY A  81
ALA A  83
SER A  85
LEU A  86
 None
 0.82A 3rr3A-4j9uA:
3.2		 3rr3A-4j9uA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RR3_B_FLRB700_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		5 / 12 VAL A  45
GLY A  81
ALA A  83
SER A  85
LEU A  86
 None
 1.03A 3rr3B-4j9uA:
undetectable		 3rr3B-4j9uA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RR3_B_FLRB700_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		5 / 12 VAL A  79
GLY A  81
ALA A  83
SER A  85
LEU A  86
 None
 0.82A 3rr3B-4j9uA:
undetectable		 3rr3B-4j9uA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_C_ZMRC601_2
(NEURAMINIDASE)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		3 / 3 ARG A   8
ARG A  58
ILE A   9
 None
 0.79A 4b7qC-4j9uA:
undetectable		 4b7qC-4j9uA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COX_A_IMNA701_1
(CYCLOOXYGENASE-2)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		6 / 12 LEU A 109
VAL A  79
GLY A  81
ALA A  83
SER A  85
LEU A  86
 None
 1.44A 4coxA-4j9uA:
2.9		 4coxA-4j9uA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COX_B_IMNB701_1
(CYCLOOXYGENASE-2)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		6 / 12 LEU A 109
VAL A  79
GLY A  81
ALA A  83
SER A  85
LEU A  86
 None
 1.43A 4coxB-4j9uA:
3.3		 4coxB-4j9uA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COX_C_IMNC701_1
(CYCLOOXYGENASE-2)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		5 / 12 VAL A  79
GLY A  81
ALA A  83
SER A  85
LEU A  86
 None
 0.82A 4coxC-4j9uA:
3.3		 4coxC-4j9uA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COX_D_IMND701_1
(CYCLOOXYGENASE-2)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		6 / 12 LEU A 109
VAL A  79
GLY A  81
ALA A  83
SER A  85
LEU A  86
 None
 1.43A 4coxD-4j9uA:
3.3		 4coxD-4j9uA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_A_URFA1301_1
(URIDINE
PHOSPHORYLASE)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		4 / 8 THR A 352
GLY A 141
ILE A 143
VAL A 144
 None
 0.82A 4e1vA-4j9uA:
undetectable		 4e1vA-4j9uA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_C_URFC1301_1
(URIDINE
PHOSPHORYLASE)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		4 / 8 THR A 352
GLY A 141
ILE A 143
VAL A 144
 None
 0.82A 4e1vC-4j9uA:
undetectable		 4e1vC-4j9uA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_D_URFD1301_1
(URIDINE
PHOSPHORYLASE)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		4 / 8 THR A 352
GLY A 141
ILE A 143
VAL A 144
 None
 0.82A 4e1vD-4j9uA:
undetectable		 4e1vD-4j9uA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_E_URFE1301_1
(URIDINE
PHOSPHORYLASE)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		4 / 8 THR A 352
GLY A 141
ILE A 143
VAL A 144
 None
 0.81A 4e1vE-4j9uA:
undetectable		 4e1vE-4j9uA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_G_URFG1301_1
(URIDINE
PHOSPHORYLASE)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		4 / 8 GLY A 346
GLN A 283
ILE A 361
VAL A 358
 None
 1.00A 4e1vG-4j9uA:
undetectable		 4e1vG-4j9uA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_G_URFG1301_1
(URIDINE
PHOSPHORYLASE)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		4 / 8 THR A 352
GLY A 141
ILE A 143
VAL A 144
 None
 0.88A 4e1vG-4j9uA:
undetectable		 4e1vG-4j9uA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_H_URFH1301_1
(URIDINE
PHOSPHORYLASE)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		4 / 8 THR A 352
GLY A 141
ILE A 143
VAL A 144
 None
 0.83A 4e1vH-4j9uA:
undetectable		 4e1vH-4j9uA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I13_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		3 / 3 ASP A 209
ARG A  32
THR A 225
 None
 0.70A 4i13A-4j9uA:
undetectable		 4i13A-4j9uA:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OTY_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		6 / 12 LEU A 109
VAL A  79
GLY A  81
ALA A  83
SER A  85
LEU A  86
 None
 1.40A 4otyA-4j9uA:
undetectable		 4otyA-4j9uA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OTY_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		6 / 12 LEU A 109
VAL A  79
GLY A  81
ALA A  83
SER A  85
LEU A  86
 None
 1.39A 4otyB-4j9uA:
3.0		 4otyB-4j9uA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P3R_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		3 / 3 ASP A 209
ARG A  32
THR A 225
 None
 0.70A 4p3rA-4j9uA:
undetectable		 4p3rA-4j9uA:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_A_SHHA404_2
(HISTONE DEACETYLASE
8)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		3 / 3 PRO A  24
MET A  21
TYR A 130
 None
 0.82A 4qa0B-4j9uA:
undetectable		 4qa0B-4j9uA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_B_SHHB404_1
(HISTONE DEACETYLASE
8)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		3 / 3 PRO A  24
MET A  21
TYR A 130
 None
 0.84A 4qa0A-4j9uA:
undetectable		 4qa0A-4j9uA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_A_SHHA404_2
(HISTONE DEACETYLASE
8)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		3 / 3 PRO A  24
MET A  21
TYR A 130
 None
 0.97A 4qa2B-4j9uA:
undetectable		 4qa2B-4j9uA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB307_1
(CHITOSANASE)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		4 / 7 GLY A 327
THR A 324
VAL A 445
HIS A 448
 None
 0.92A 4qwpB-4j9uA:
undetectable		 4qwpB-4j9uA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R82_A_ACTA205_0
(OXIDOREDUCTASE)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		4 / 5 GLY A 355
ARG A 360
GLU A 470
PHE A 402
 None
 1.23A 4r82A-4j9uA:
undetectable
4r82B-4j9uA:
undetectable		 4r82A-4j9uA:
15.85
4r82B-4j9uA:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		5 / 12 VAL A  79
GLY A  81
ALA A  83
SER A  85
LEU A  86
 None
 0.83A 4rrwA-4j9uA:
3.5		 4rrwA-4j9uA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		5 / 12 VAL A  79
GLY A  81
ALA A  83
SER A  85
LEU A  86
 None
 0.82A 4rrwB-4j9uA:
0.0		 4rrwB-4j9uA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_C_LURC705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		6 / 12 LEU A 109
VAL A  79
GLY A  81
ALA A  83
SER A  85
LEU A  86
 None
 1.44A 4rrwC-4j9uA:
3.4		 4rrwC-4j9uA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_D_LURD705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		6 / 12 LEU A 109
VAL A  79
GLY A  81
ALA A  83
SER A  85
LEU A  86
 None
 1.43A 4rrwD-4j9uA:
3.0		 4rrwD-4j9uA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRX_A_LURA706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		5 / 12 VAL A  79
GLY A  81
ALA A  83
SER A  85
LEU A  86
 None
 0.77A 4rrxA-4j9uA:
0.7		 4rrxA-4j9uA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRX_B_LURB706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		5 / 12 VAL A  79
GLY A  81
ALA A  83
SER A  85
LEU A  86
 None
 0.76A 4rrxB-4j9uA:
2.9		 4rrxB-4j9uA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		5 / 12 VAL A  79
GLY A  81
ALA A  83
SER A  85
LEU A  86
 None
 0.83A 4rrzA-4j9uA:
3.5		 4rrzA-4j9uA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		5 / 12 VAL A  79
GLY A  81
ALA A  83
SER A  85
LEU A  86
 None
 0.82A 4rrzB-4j9uA:
0.0		 4rrzB-4j9uA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_C_LURC705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		6 / 12 LEU A 109
VAL A  79
GLY A  81
ALA A  83
SER A  85
LEU A  86
 None
 1.44A 4rrzC-4j9uA:
3.4		 4rrzC-4j9uA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_D_LURD705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		6 / 12 LEU A 109
VAL A  79
GLY A  81
ALA A  83
SER A  85
LEU A  86
 None
 1.43A 4rrzD-4j9uA:
3.0		 4rrzD-4j9uA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBR_A_NPSA602_1
(SERUM ALBUMIN)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		5 / 12 LEU A  80
GLY A  11
CYH A  53
LEU A  46
SER A  85
 None
 1.31A 4zbrA-4j9uA:
2.9		 4zbrA-4j9uA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_B_CHDB303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		5 / 11 MET A 356
GLY A 355
THR A 110
THR A 112
PHE A 466
 None
 1.40A 5b1bA-4j9uA:
4.5
5b1bB-4j9uA:
undetectable
5b1bT-4j9uA:
undetectable		 5b1bA-4j9uA:
23.60
5b1bB-4j9uA:
18.89
5b1bT-4j9uA:
10.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_G_CHDG103_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		5 / 11 PHE A 466
MET A 356
GLY A 355
THR A 110
THR A 112
 None
 1.38A 5b1bG-4j9uA:
undetectable
5b1bN-4j9uA:
2.3
5b1bO-4j9uA:
undetectable		 5b1bG-4j9uA:
10.92
5b1bN-4j9uA:
23.60
5b1bO-4j9uA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_B_CHDB304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		5 / 11 MET A 356
GLY A 355
THR A 110
THR A 112
PHE A 466
 None
 1.37A 5b3sA-4j9uA:
1.6
5b3sB-4j9uA:
undetectable
5b3sT-4j9uA:
undetectable		 5b3sA-4j9uA:
23.60
5b3sB-4j9uA:
18.89
5b3sT-4j9uA:
10.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_G_CHDG102_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		5 / 10 PHE A 466
MET A 356
GLY A 355
THR A 110
THR A 112
 None
 1.37A 5b3sG-4j9uA:
undetectable
5b3sN-4j9uA:
0.7
5b3sO-4j9uA:
undetectable		 5b3sG-4j9uA:
10.92
5b3sN-4j9uA:
23.60
5b3sO-4j9uA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_B_ACTB404_0
(D-ALANINE--D-ALANINE
LIGASE)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		4 / 7 TYR A 130
GLY A  84
SER A 105
LEU A 109
 None
 1.16A 5bphB-4j9uA:
undetectable		 5bphB-4j9uA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_P_BEZP801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		4 / 6 PHE A 341
SER A 429
ALA A 432
LEU A 442
 None
 1.10A 5dzkB-4j9uA:
undetectable
5dzkP-4j9uA:
undetectable		 5dzkB-4j9uA:
16.63
5dzkP-4j9uA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_U_BEZU801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		4 / 6 PHE A 341
SER A 429
ALA A 432
LEU A 442
 None
 1.29A 5dzkg-4j9uA:
undetectable
5dzku-4j9uA:
undetectable		 5dzkg-4j9uA:
16.63
5dzku-4j9uA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHG_C_SAMC4001_0
(RNA-DIRECTED RNA
POLYMERASE NS5)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		5 / 12 GLY A 346
GLY A 354
GLY A 350
THR A 320
ILE A 345
 None
 0.95A 5ehgC-4j9uA:
undetectable		 5ehgC-4j9uA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHI_C_SAMC4000_0
(NS5
METHYLTRANSFERASE
DENGUE VIRUS)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		5 / 12 GLY A 346
GLY A 354
GLY A 350
THR A 320
ILE A 345
 None
 0.94A 5ehiC-4j9uA:
undetectable		 5ehiC-4j9uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HES_A_032A401_2
(MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE MLT)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		4 / 6 PHE A 102
LYS A 457
SER A  85
ASP A 100
 None
 1.23A 5hesA-4j9uA:
undetectable		 5hesA-4j9uA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKQ_A_JMSA602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		5 / 12 VAL A  79
GLY A  81
ALA A  83
SER A  85
LEU A  86
 None
 0.82A 5ikqA-4j9uA:
1.6		 5ikqA-4j9uA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKQ_B_JMSB602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		5 / 12 VAL A  79
GLY A  81
ALA A  83
SER A  85
LEU A  86
 None
 0.84A 5ikqB-4j9uA:
2.1		 5ikqB-4j9uA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_A_ID8A601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		5 / 12 VAL A  79
GLY A  81
ALA A  83
SER A  85
LEU A  86
 None
 0.79A 5ikrA-4j9uA:
0.0		 5ikrA-4j9uA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_B_ID8B602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		5 / 12 VAL A  79
GLY A  81
ALA A  83
SER A  85
LEU A  86
 None
 0.83A 5ikrB-4j9uA:
1.9		 5ikrB-4j9uA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JVZ_A_FLPA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		5 / 12 VAL A  79
GLY A  81
ALA A  83
SER A  85
LEU A  86
 None
 0.89A 5jvzA-4j9uA:
3.4		 5jvzA-4j9uA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_A_CELA602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		5 / 12 VAL A  79
GLY A  81
ALA A  83
SER A  85
LEU A  86
 None
 0.79A 5jw1A-4j9uA:
2.8		 5jw1A-4j9uA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_A_RCXA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		5 / 12 VAL A  79
GLY A  81
ALA A  83
SER A  85
LEU A  86
 None
 0.92A 5kirA-4j9uA:
3.1		 5kirA-4j9uA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_B_RCXB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		5 / 12 VAL A  79
GLY A  81
ALA A  83
SER A  85
LEU A  86
 None
 0.93A 5kirB-4j9uA:
0.0		 5kirB-4j9uA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQR_A_SAMA301_0
(METHYLTRANSFERASE)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		5 / 12 GLY A 346
GLY A 354
GLY A 350
THR A 320
ILE A 345
 None
 0.94A 5kqrA-4j9uA:
undetectable		 5kqrA-4j9uA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5B_A_SAMA1001_0
(NS5
METHYLTRANSFERASE)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		5 / 12 GLY A 346
GLY A 354
GLY A 350
THR A 320
ILE A 345
 None
 0.94A 5m5bA-4j9uA:
undetectable		 5m5bA-4j9uA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_C_ADNC502_1
(ADENOSYLHOMOCYSTEINA
SE)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		5 / 12 THR A 325
GLN A 313
ASP A 305
THR A 301
GLY A 327
 None
 1.37A 5m66C-4j9uA:
undetectable		 5m66C-4j9uA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUG_A_VIVA301_1
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		3 / 3 SER A 229
SER A 224
PHE A 312
 None
 0.94A 5mugA-4j9uA:
undetectable		 5mugA-4j9uA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_B_CHDB302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		5 / 10 MET A 356
GLY A 355
THR A 110
THR A 112
PHE A 466
 None
 1.30A 5x1fA-4j9uA:
0.8
5x1fB-4j9uA:
undetectable
5x1fT-4j9uA:
undetectable		 5x1fA-4j9uA:
23.60
5x1fB-4j9uA:
18.89
5x1fT-4j9uA:
10.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_G_CHDG104_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		5 / 11 PHE A 466
MET A 356
GLY A 355
THR A 110
THR A 112
 None
 1.28A 5x1fG-4j9uA:
undetectable
5x1fN-4j9uA:
1.7
5x1fO-4j9uA:
undetectable		 5x1fG-4j9uA:
10.92
5x1fN-4j9uA:
23.60
5x1fO-4j9uA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_A_8LXA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		5 / 12 PHE A 137
GLY A 139
LEU A 190
ILE A 218
LEU A  16
 None
 1.01A 5y2tA-4j9uA:
undetectable		 5y2tA-4j9uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_B_CHDB301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		5 / 11 MET A 356
GLY A 355
THR A 110
THR A 112
PHE A 466
 None
 1.41A 5z84A-4j9uA:
undetectable
5z84B-4j9uA:
undetectable
5z84T-4j9uA:
undetectable		 5z84A-4j9uA:
23.60
5z84B-4j9uA:
18.89
5z84T-4j9uA:
10.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_G_CHDG101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		5 / 10 PHE A 466
MET A 356
GLY A 355
THR A 110
THR A 112
 None
 1.37A 5z84G-4j9uA:
undetectable
5z84N-4j9uA:
2.4
5z84O-4j9uA:
undetectable		 5z84G-4j9uA:
10.92
5z84N-4j9uA:
23.60
5z84O-4j9uA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_G_CHDG103_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		5 / 10 PHE A 466
MET A 356
GLY A 355
THR A 110
THR A 112
 None
 1.37A 5z85G-4j9uA:
undetectable
5z85N-4j9uA:
2.6
5z85O-4j9uA:
undetectable		 5z85G-4j9uA:
10.92
5z85N-4j9uA:
23.60
5z85O-4j9uA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_T_CHDT101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		5 / 10 MET A 356
GLY A 355
THR A 110
THR A 112
PHE A 466
 None
 1.39A 5z85A-4j9uA:
2.4
5z85B-4j9uA:
undetectable
5z85T-4j9uA:
undetectable		 5z85A-4j9uA:
23.60
5z85B-4j9uA:
18.89
5z85T-4j9uA:
10.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_B_CHDB302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		5 / 11 MET A 356
GLY A 355
THR A 110
THR A 112
PHE A 466
 None
 1.40A 5z86A-4j9uA:
2.6
5z86B-4j9uA:
undetectable
5z86T-4j9uA:
undetectable		 5z86A-4j9uA:
23.60
5z86B-4j9uA:
18.89
5z86T-4j9uA:
10.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_G_CHDG103_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		5 / 10 PHE A 466
MET A 356
GLY A 355
THR A 110
THR A 112
 None
 1.37A 5z86G-4j9uA:
undetectable
5z86N-4j9uA:
4.7
5z86O-4j9uA:
undetectable		 5z86G-4j9uA:
10.92
5z86N-4j9uA:
23.60
5z86O-4j9uA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_B_CHDB301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		5 / 11 MET A 356
GLY A 355
THR A 110
THR A 112
PHE A 466
 None
 1.40A 5zcqA-4j9uA:
4.4
5zcqB-4j9uA:
undetectable
5zcqT-4j9uA:
undetectable		 5zcqA-4j9uA:
23.60
5zcqB-4j9uA:
18.89
5zcqT-4j9uA:
10.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_G_CHDG103_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		5 / 10 PHE A 466
MET A 356
GLY A 355
THR A 110
THR A 112
 None
 1.36A 5zcqG-4j9uA:
undetectable
5zcqN-4j9uA:
1.8
5zcqO-4j9uA:
undetectable		 5zcqG-4j9uA:
10.92
5zcqN-4j9uA:
23.60
5zcqO-4j9uA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		5 / 12 TYR A 300
SER A 302
TYR A 236
ALA A 306
LEU A 294
 None
 1.41A 5zwrB-4j9uA:
undetectable		 5zwrB-4j9uA:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EU9_D_READ601_1
(RETINOIC ACID
RECEPTOR)		 4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH
(Vibrio
parahaemolyticus) 		4 / 7 LEU A 134
LEU A  12
GLY A  50
GLY A  84
 None
 0.73A 6eu9D-4j9uA:
undetectable		 6eu9D-4j9uA:
11.36