SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4j9v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSH_A_MK1A401_1
(HIV-II PROTEASE)		 4j9v POTASSIUM UPTAKE
PROTEIN TRKA
(Vibrio
parahaemolyticus) 		5 / 12 ILE A   3
VAL A 362
ILE A 355
ILE A  28
ILE A  26
 None
 0.83A 1hshA-4j9vA:
undetectable		 1hshA-4j9vA:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7F_A_BCZA801_0
(NEURAMINIDASE)		 4j9v POTASSIUM UPTAKE
PROTEIN TRKA
(Vibrio
parahaemolyticus) 		5 / 12 GLU A 208
ARG A 375
ILE A 195
ARG A 190
GLU A 204
 None
 1.43A 1l7fA-4j9vA:
undetectable		 1l7fA-4j9vA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7H_A_BCZA801_0
(NEURAMINIDASE)		 4j9v POTASSIUM UPTAKE
PROTEIN TRKA
(Vibrio
parahaemolyticus) 		5 / 12 GLU A 208
ARG A 375
ILE A 195
ARG A 190
GLU A 204
 None
 1.41A 1l7hA-4j9vA:
undetectable		 1l7hA-4j9vA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZZ_A_SAMA635_0
(ACLACINOMYCIN-10-HYD
ROXYLASE)		 4j9v POTASSIUM UPTAKE
PROTEIN TRKA
(Vibrio
parahaemolyticus) 		5 / 12 GLY A 239
GLY A 240
GLU A 261
ASP A 283
ASN A 306
 AGS  A 502 (-3.3A)
AGS  A 502 ( 4.9A)
AGS  A 502 (-2.4A)
AGS  A 502 (-2.9A)
AGS  A 502 (-2.8A)
 0.95A 1qzzA-4j9vA:
8.3		 1qzzA-4j9vA:
26.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQP_B_SAMB500_1
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)		 4j9v POTASSIUM UPTAKE
PROTEIN TRKA
(Vibrio
parahaemolyticus) 		4 / 8 ASP A 308
ASN A 311
SER A 349
ALA A 303
 None
 1.09A 1rqpC-4j9vA:
undetectable		 1rqpC-4j9vA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQP_C_SAMC500_0
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)		 4j9v POTASSIUM UPTAKE
PROTEIN TRKA
(Vibrio
parahaemolyticus) 		4 / 8 ASP A 308
ASN A 311
SER A 349
ALA A 303
 None
 1.10A 1rqpA-4j9vA:
undetectable		 1rqpA-4j9vA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UWJ_A_BAXA1723_2
(B-RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE)		 4j9v POTASSIUM UPTAKE
PROTEIN TRKA
(Vibrio
parahaemolyticus) 		4 / 7 LEU A 136
ILE A 348
ILE A 302
ASP A 345
 None
 0.72A 1uwjA-4j9vA:
undetectable		 1uwjA-4j9vA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VPT_A_SAMA400_0
(VP39)		 4j9v POTASSIUM UPTAKE
PROTEIN TRKA
(Vibrio
parahaemolyticus) 		5 / 12 ILE A   3
VAL A 362
VAL A  70
ALA A  71
LEU A  15
 None
 0.99A 1vptA-4j9vA:
5.5		 1vptA-4j9vA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VPT_A_SAMA400_0
(VP39)		 4j9v POTASSIUM UPTAKE
PROTEIN TRKA
(Vibrio
parahaemolyticus) 		5 / 12 LEU A  58
ILE A   3
VAL A 362
VAL A  70
LEU A  15
 None
 0.93A 1vptA-4j9vA:
5.5		 1vptA-4j9vA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDS_A_SAMA5635_0
(PROTEIN RDMB)		 4j9v POTASSIUM UPTAKE
PROTEIN TRKA
(Vibrio
parahaemolyticus) 		5 / 12 GLY A 239
GLY A 240
GLU A 261
ASP A 283
ASN A 306
 AGS  A 502 (-3.3A)
AGS  A 502 ( 4.9A)
AGS  A 502 (-2.4A)
AGS  A 502 (-2.9A)
AGS  A 502 (-2.8A)
 1.19A 1xdsA-4j9vA:
6.3		 1xdsA-4j9vA:
26.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDS_B_SAMB9635_0
(PROTEIN RDMB)		 4j9v POTASSIUM UPTAKE
PROTEIN TRKA
(Vibrio
parahaemolyticus) 		5 / 12 GLY A 239
GLY A 240
GLU A 261
ASP A 283
ASN A 306
 AGS  A 502 (-3.3A)
AGS  A 502 ( 4.9A)
AGS  A 502 (-2.4A)
AGS  A 502 (-2.9A)
AGS  A 502 (-2.8A)
 1.08A 1xdsB-4j9vA:
7.4		 1xdsB-4j9vA:
26.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOT_B_VDNB102_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4B)		 4j9v POTASSIUM UPTAKE
PROTEIN TRKA
(Vibrio
parahaemolyticus) 		5 / 12 LEU A 304
ASN A 311
ILE A 330
SER A 356
GLN A 331
 None
 1.49A 1xotB-4j9vA:
undetectable		 1xotB-4j9vA:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OA1_B_ADNB2005_1
(TRYPTOPHAN
HALOGENASE)		 4j9v POTASSIUM UPTAKE
PROTEIN TRKA
(Vibrio
parahaemolyticus) 		4 / 7 GLY A  12
GLY A   9
VAL A  70
LEU A 358
 None
AGS  A 501 (-3.4A)
None
None
 0.79A 2oa1B-4j9vA:
6.3		 2oa1B-4j9vA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FUU_A_ADNA0_1
(DIMETHYLADENOSINE
TRANSFERASE)		 4j9v POTASSIUM UPTAKE
PROTEIN TRKA
(Vibrio
parahaemolyticus) 		7 / 12 VAL A 238
GLY A 239
GLY A 241
GLU A 261
ASP A 263
ASP A 283
ALA A 284
 None
AGS  A 502 (-3.3A)
AGS  A 502 (-3.1A)
AGS  A 502 (-2.4A)
None
AGS  A 502 (-2.9A)
AGS  A 502 (-3.2A)
 0.97A 3fuuA-4j9vA:
9.8		 3fuuA-4j9vA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GRV_A_ADNA300_1
(DIMETHYLADENOSINE
TRANSFERASE)		 4j9v POTASSIUM UPTAKE
PROTEIN TRKA
(Vibrio
parahaemolyticus) 		7 / 11 GLY A 239
GLY A 241
GLU A 261
ASP A 263
ASP A 283
ALA A 284
ASN A 306
 AGS  A 502 (-3.3A)
AGS  A 502 (-3.1A)
AGS  A 502 (-2.4A)
None
AGS  A 502 (-2.9A)
AGS  A 502 (-3.2A)
AGS  A 502 (-2.8A)
 1.23A 3grvA-4j9vA:
10.6		 3grvA-4j9vA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GRY_A_SAMA300_0
(DIMETHYLADENOSINE
TRANSFERASE)		 4j9v POTASSIUM UPTAKE
PROTEIN TRKA
(Vibrio
parahaemolyticus) 		7 / 12 GLY A 239
GLY A 241
GLU A 261
ASP A 263
ASP A 283
ALA A 284
ASN A 306
 AGS  A 502 (-3.3A)
AGS  A 502 (-3.1A)
AGS  A 502 (-2.4A)
None
AGS  A 502 (-2.9A)
AGS  A 502 (-3.2A)
AGS  A 502 (-2.8A)
 1.33A 3gryA-4j9vA:
10.5		 3gryA-4j9vA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GYQ_B_SAMB270_0
(RRNA
(ADENOSINE-2'-O-)-ME
THYLTRANSFERASE)		 4j9v POTASSIUM UPTAKE
PROTEIN TRKA
(Vibrio
parahaemolyticus) 		5 / 11 LEU A   6
ALA A   8
GLY A  50
ILE A   5
VAL A  48
 None
 1.12A 3gyqB-4j9vA:
3.1		 3gyqB-4j9vA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_C_MTXC164_2
(DIHYDROFOLATE
REDUCTASE)		 4j9v POTASSIUM UPTAKE
PROTEIN TRKA
(Vibrio
parahaemolyticus) 		4 / 4 ILE A   5
ARG A 364
ILE A   3
THR A  14
 None
 1.06A 3ia4C-4j9vA:
undetectable		 3ia4C-4j9vA:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZS_A_SAMA1475_0
(METHYLTRANSFERASE
WBDD)		 4j9v POTASSIUM UPTAKE
PROTEIN TRKA
(Vibrio
parahaemolyticus) 		5 / 12 GLN A 452
ASN A  23
ILE A 381
GLU A 379
VAL A 447
 None
 1.28A 4azsA-4j9vA:
9.9		 4azsA-4j9vA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZW_A_SAMA1451_0
(WBDD)		 4j9v POTASSIUM UPTAKE
PROTEIN TRKA
(Vibrio
parahaemolyticus) 		5 / 12 GLN A 452
ASN A  23
ILE A 381
GLU A 379
VAL A 447
 None
 1.22A 4azwA-4j9vA:
10.1		 4azwA-4j9vA:
23.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4j9v POTASSIUM UPTAKE
PROTEIN TRKA
(Vibrio
parahaemolyticus) 		4 / 8 PHE A 210
GLU A 379
SER A 371
VAL A 146
 None
 1.38A 4capA-4j9vA:
undetectable
4capB-4j9vA:
undetectable		 4capA-4j9vA:
21.51
4capB-4j9vA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GC9_A_SAMA401_1
(DIMETHYLADENOSINE
TRANSFERASE 1,
MITOCHONDRIAL)		 4j9v POTASSIUM UPTAKE
PROTEIN TRKA
(Vibrio
parahaemolyticus) 		3 / 3 GLU A 261
ASP A 263
ASP A 283
 AGS  A 502 (-2.4A)
None
AGS  A 502 (-2.9A)
 0.26A 4gc9A-4j9vA:
6.8		 4gc9A-4j9vA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWV_A_BCZA513_0
(NEURAMINIDASE)		 4j9v POTASSIUM UPTAKE
PROTEIN TRKA
(Vibrio
parahaemolyticus) 		5 / 12 GLU A 208
ARG A 375
ILE A 195
ARG A 190
GLU A 204
 None
 1.44A 4mwvA-4j9vA:
undetectable		 4mwvA-4j9vA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_C_ACTC202_0
(RETINOL-BINDING
PROTEIN 2)		 4j9v POTASSIUM UPTAKE
PROTEIN TRKA
(Vibrio
parahaemolyticus) 		4 / 6 TYR A 132
GLU A 208
GLN A 340
LEU A 136
 None
 1.16A 4qzuC-4j9vA:
undetectable		 4qzuC-4j9vA:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4j9v POTASSIUM UPTAKE
PROTEIN TRKA
(Vibrio
parahaemolyticus) 		5 / 12 LEU A 155
SER A 154
VAL A 435
GLY A 411
ALA A 412
 None
 1.16A 4rrwA-4j9vA:
undetectable		 4rrwA-4j9vA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4j9v POTASSIUM UPTAKE
PROTEIN TRKA
(Vibrio
parahaemolyticus) 		5 / 12 LEU A 155
SER A 154
VAL A 435
GLY A 411
ALA A 412
 None
 1.19A 4rrwB-4j9vA:
undetectable		 4rrwB-4j9vA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4j9v POTASSIUM UPTAKE
PROTEIN TRKA
(Vibrio
parahaemolyticus) 		5 / 12 LEU A 155
SER A 154
VAL A 435
GLY A 411
ALA A 412
 None
 1.16A 4rrzA-4j9vA:
undetectable		 4rrzA-4j9vA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4j9v POTASSIUM UPTAKE
PROTEIN TRKA
(Vibrio
parahaemolyticus) 		5 / 12 LEU A 155
SER A 154
VAL A 435
GLY A 411
ALA A 412
 None
 1.19A 4rrzB-4j9vA:
undetectable		 4rrzB-4j9vA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YVP_A_GBMA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C1)		 4j9v POTASSIUM UPTAKE
PROTEIN TRKA
(Vibrio
parahaemolyticus) 		5 / 11 TYR A 232
LEU A 136
ILE A 348
LEU A 251
LEU A 247
 None
 1.49A 4yvpA-4j9vA:
2.8		 4yvpA-4j9vA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E72_A_SAMA400_0
(N2,
N2-DIMETHYLGUANOSINE
TRNA
METHYLTRANSFERASE)		 4j9v POTASSIUM UPTAKE
PROTEIN TRKA
(Vibrio
parahaemolyticus) 		5 / 12 PHE A 189
GLY A 341
ILE A 195
ALA A 187
ASP A 337
 None
 0.98A 5e72A-4j9vA:
9.2		 5e72A-4j9vA:
25.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERG_B_SAMB401_1
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
CATALYTIC SUBUNIT
TRM61)		 4j9v POTASSIUM UPTAKE
PROTEIN TRKA
(Vibrio
parahaemolyticus) 		4 / 7 GLY A 239
GLY A 241
GLU A 261
ASP A 283
 AGS  A 502 (-3.3A)
AGS  A 502 (-3.1A)
AGS  A 502 (-2.4A)
AGS  A 502 (-2.9A)
 0.74A 5ergB-4j9vA:
9.6		 5ergB-4j9vA:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_A_ID8A601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4j9v POTASSIUM UPTAKE
PROTEIN TRKA
(Vibrio
parahaemolyticus) 		5 / 12 LEU A 155
SER A 154
VAL A 435
GLY A 411
ALA A 412
 None
 1.00A 5ikrA-4j9vA:
undetectable		 5ikrA-4j9vA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR0_A_478A101_1
(PROTEASE E35D-APV)		 4j9v POTASSIUM UPTAKE
PROTEIN TRKA
(Vibrio
parahaemolyticus) 		5 / 9 ASN A 311
ALA A 303
ILE A 133
GLY A 244
PRO A 350
 None
 1.15A 5kr0A-4j9vA:
undetectable		 5kr0A-4j9vA:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_A_ROCA101_1
(PROTEASE PR5-SQV)		 4j9v POTASSIUM UPTAKE
PROTEIN TRKA
(Vibrio
parahaemolyticus) 		5 / 9 ASN A 311
ALA A 303
ILE A 133
GLY A 244
PRO A 350
 None
 1.13A 5kr2A-4j9vA:
undetectable		 5kr2A-4j9vA:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OJ0_A_9WTA801_0
(PENICILLIN-BINDING
PROTEIN 2X)		 4j9v POTASSIUM UPTAKE
PROTEIN TRKA
(Vibrio
parahaemolyticus) 		5 / 12 GLN A 331
GLN A 351
GLY A  13
THR A  14
GLN A 352
 None
AGS  A 501 (-3.9A)
None
None
None
 1.30A 5oj0A-4j9vA:
undetectable		 5oj0A-4j9vA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_A_SAMA901_0
(MRNA CAPPING ENZYME
P5)		 4j9v POTASSIUM UPTAKE
PROTEIN TRKA
(Vibrio
parahaemolyticus) 		5 / 11 VAL A 238
GLY A 239
GLU A 261
ASP A 283
ALA A 284
 None
AGS  A 502 (-3.3A)
AGS  A 502 (-2.4A)
AGS  A 502 (-2.9A)
AGS  A 502 (-3.2A)
 0.79A 5x6yA-4j9vA:
3.4		 5x6yA-4j9vA:
20.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_B_SAMB901_0
(MRNA CAPPING ENZYME
P5)		 4j9v POTASSIUM UPTAKE
PROTEIN TRKA
(Vibrio
parahaemolyticus) 		5 / 10 VAL A 238
GLY A 239
GLU A 261
ALA A 284
ASN A 306
 None
AGS  A 502 (-3.3A)
AGS  A 502 (-2.4A)
AGS  A 502 (-3.2A)
AGS  A 502 (-2.8A)
 1.19A 5x6yB-4j9vA:
undetectable		 5x6yB-4j9vA:
20.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_B_SAMB901_0
(MRNA CAPPING ENZYME
P5)		 4j9v POTASSIUM UPTAKE
PROTEIN TRKA
(Vibrio
parahaemolyticus) 		5 / 10 VAL A 238
GLY A 239
GLU A 261
ASP A 283
ALA A 284
 None
AGS  A 502 (-3.3A)
AGS  A 502 (-2.4A)
AGS  A 502 (-2.9A)
AGS  A 502 (-3.2A)
 0.76A 5x6yB-4j9vA:
undetectable		 5x6yB-4j9vA:
20.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_C_SAMC901_0
(MRNA CAPPING ENZYME
P5)		 4j9v POTASSIUM UPTAKE
PROTEIN TRKA
(Vibrio
parahaemolyticus) 		5 / 11 VAL A 238
GLY A 239
GLU A 261
ASP A 283
ALA A 284
 None
AGS  A 502 (-3.3A)
AGS  A 502 (-2.4A)
AGS  A 502 (-2.9A)
AGS  A 502 (-3.2A)
 0.63A 5x6yC-4j9vA:
5.1		 5x6yC-4j9vA:
20.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_E_CHDE401_0
(BILE SALT HYDROLASE)		 4j9v POTASSIUM UPTAKE
PROTEIN TRKA
(Vibrio
parahaemolyticus) 		4 / 8 PHE A  87
LEU A  89
ALA A  63
LEU A  69
 None
 0.86A 5y7pE-4j9vA:
undetectable		 5y7pE-4j9vA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YK2_A_ERYA501_0
(PROBABLE CONSERVED
ATP-BINDING PROTEIN
ABC TRANSPORTER)		 4j9v POTASSIUM UPTAKE
PROTEIN TRKA
(Vibrio
parahaemolyticus) 		5 / 11 GLU A 429
GLY A 400
ASP A 424
ALA A 398
ILE A 410
 None
 1.07A 5yk2A-4j9vA:
undetectable		 5yk2A-4j9vA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH3_A_017A101_0
(PROTEASE)		 4j9v POTASSIUM UPTAKE
PROTEIN TRKA
(Vibrio
parahaemolyticus) 		5 / 12 GLY A   9
ALA A   8
VAL A  47
ILE A  26
ILE A  28
 AGS  A 501 (-3.4A)
None
None
None
None
 0.83A 6dh3A-4j9vA:
undetectable		 6dh3A-4j9vA:
10.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_A_ADNA503_0
(ADENOSYLHOMOCYSTEINA
SE)		 4j9v POTASSIUM UPTAKE
PROTEIN TRKA
(Vibrio
parahaemolyticus) 		5 / 10 GLY A 239
GLY A 241
GLU A 261
ASP A 263
THR A 305
 AGS  A 502 (-3.3A)
AGS  A 502 (-3.1A)
AGS  A 502 (-2.4A)
None
AGS  A 502 (-4.1A)
 0.78A 6exiA-4j9vA:
9.1		 6exiA-4j9vA:
9.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_B_ADNB503_1
(ADENOSYLHOMOCYSTEINA
SE)		 4j9v POTASSIUM UPTAKE
PROTEIN TRKA
(Vibrio
parahaemolyticus) 		5 / 10 GLY A 239
GLY A 241
GLU A 261
ASP A 263
THR A 305
 AGS  A 502 (-3.3A)
AGS  A 502 (-3.1A)
AGS  A 502 (-2.4A)
None
AGS  A 502 (-4.1A)
 0.79A 6exiB-4j9vA:
9.1		 6exiB-4j9vA:
9.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_C_ADNC503_0
(ADENOSYLHOMOCYSTEINA
SE)		 4j9v POTASSIUM UPTAKE
PROTEIN TRKA
(Vibrio
parahaemolyticus) 		5 / 12 GLY A 239
GLY A 241
GLU A 261
ASP A 263
THR A 305
 AGS  A 502 (-3.3A)
AGS  A 502 (-3.1A)
AGS  A 502 (-2.4A)
None
AGS  A 502 (-4.1A)
 0.79A 6exiC-4j9vA:
9.0
6exiD-4j9vA:
9.0		 6exiC-4j9vA:
9.66
6exiD-4j9vA:
9.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_D_ADND503_0
(ADENOSYLHOMOCYSTEINA
SE)		 4j9v POTASSIUM UPTAKE
PROTEIN TRKA
(Vibrio
parahaemolyticus) 		5 / 12 GLY A 239
GLY A 241
GLU A 261
ASP A 263
THR A 305
 AGS  A 502 (-3.3A)
AGS  A 502 (-3.1A)
AGS  A 502 (-2.4A)
None
AGS  A 502 (-4.1A)
 0.77A 6exiC-4j9vA:
9.0
6exiD-4j9vA:
9.0		 6exiC-4j9vA:
9.66
6exiD-4j9vA:
9.66