SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4jb6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_A_HLTA4001_1
(SERUM ALBUMIN)		 4jb6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Pseudomonas
aeruginosa) 		4 / 5 ARG A 253
ALA A 252
ASP A  88
GLY A  90
 None
 1.20A 1e7bA-4jb6A:
undetectable		 1e7bA-4jb6A:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_G_AG2G7003_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 4jb6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Pseudomonas
aeruginosa) 		4 / 6 LEU A  73
ASP A 234
GLY A  52
ILE A  38
 None
 0.88A 1mt1G-4jb6A:
0.0
1mt1J-4jb6A:
undetectable		 1mt1G-4jb6A:
9.62
1mt1J-4jb6A:
15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_K_AG2K7002_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 4jb6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Pseudomonas
aeruginosa) 		4 / 7 ILE A  38
LEU A  73
ASP A 234
GLY A  52
 None
 0.87A 1mt1H-4jb6A:
undetectable
1mt1K-4jb6A:
0.0		 1mt1H-4jb6A:
15.03
1mt1K-4jb6A:
9.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT2_A_SAMA301_0
(FIBRILLARIN-LIKE
PRE-RRNA PROCESSING
PROTEIN)		 4jb6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Pseudomonas
aeruginosa) 		6 / 12 GLY A 167
SER A 107
THR A 162
SER A 236
ALA A 351
ILE A 171
 None
 1.24A 1nt2A-4jb6A:
undetectable		 1nt2A-4jb6A:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_E_BEZE509_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 4jb6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Pseudomonas
aeruginosa) 		4 / 7 ILE A 178
GLU A 243
ARG A 250
ALA A 247
 None
 1.04A 1oniD-4jb6A:
undetectable
1oniE-4jb6A:
undetectable		 1oniD-4jb6A:
15.37
1oniE-4jb6A:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_A_SAMA301_1
(HEMK PROTEIN)		 4jb6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Pseudomonas
aeruginosa) 		4 / 4 THR A 161
GLY A 111
ASP A  72
ALA A 194
 None
 1.19A 1sg9A-4jb6A:
undetectable		 1sg9A-4jb6A:
23.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_A_SAMA301_1
(HEMK PROTEIN)		 4jb6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Pseudomonas
aeruginosa) 		4 / 4 THR A 306
GLY A 402
ASP A 266
ALA A 280
 None
 1.15A 1sg9A-4jb6A:
undetectable		 1sg9A-4jb6A:
23.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVD_B_SAMB601_0
(CATECHOL-O-METHYLTRA
NSFERASE)		 4jb6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Pseudomonas
aeruginosa) 		5 / 12 GLY A  10
VAL A 187
ALA A 238
ASP A  88
ALA A  85
 None
 1.38A 2avdB-4jb6A:
undetectable		 2avdB-4jb6A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B25_B_SAMB602_0
(HYPOTHETICAL PROTEIN)		 4jb6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Pseudomonas
aeruginosa) 		5 / 12 THR A 168
THR A 162
GLY A 405
SER A 397
GLY A 399
 None
None
None
K  A 501 ( 4.6A)
None
 0.92A 2b25B-4jb6A:
undetectable		 2b25B-4jb6A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NPN_A_SAMA4633_0
(PUTATIVE COBALAMIN
SYNTHESIS RELATED
PROTEIN)		 4jb6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Pseudomonas
aeruginosa) 		5 / 9 GLY A 347
LEU A 407
THR A 168
LEU A 241
LEU A 160
 None
 1.17A 2npnA-4jb6A:
undetectable		 2npnA-4jb6A:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYU_A_SAMA201_0
(PUTATIVE RIBOSOMAL
RNA
METHYLTRANSFERASE 2)		 4jb6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Pseudomonas
aeruginosa) 		5 / 12 SER A 170
GLY A 237
ALA A 345
GLY A 347
LEU A  14
 None
 1.02A 2nyuA-4jb6A:
undetectable		 2nyuA-4jb6A:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYU_B_SAMB201_0
(PUTATIVE RIBOSOMAL
RNA
METHYLTRANSFERASE 2)		 4jb6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Pseudomonas
aeruginosa) 		5 / 12 SER A 170
GLY A 237
ALA A 345
GLY A 347
LEU A  14
 None
 1.05A 2nyuB-4jb6A:
undetectable		 2nyuB-4jb6A:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_E_AG2E671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 4jb6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Pseudomonas
aeruginosa) 		4 / 7 ILE A  38
LEU A  73
ASP A 234
GLY A  52
 None
 0.87A 2qqcD-4jb6A:
undetectable
2qqcE-4jb6A:
0.0		 2qqcD-4jb6A:
13.99
2qqcE-4jb6A:
9.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_K_AG2K671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 4jb6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Pseudomonas
aeruginosa) 		4 / 8 ILE A  38
LEU A  73
ASP A 234
GLY A  52
 None
 0.86A 2qqcH-4jb6A:
0.1
2qqcK-4jb6A:
undetectable		 2qqcH-4jb6A:
13.99
2qqcK-4jb6A:
9.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQD_B_AG2B671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 4jb6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Pseudomonas
aeruginosa) 		4 / 8 ILE A  38
LEU A  73
ASP A 234
GLY A  52
 None
 0.81A 2qqdB-4jb6A:
0.3
2qqdC-4jb6A:
undetectable		 2qqdB-4jb6A:
13.99
2qqdC-4jb6A:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VMY_B_FFOB505_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4jb6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Pseudomonas
aeruginosa) 		6 / 12 LEU A 258
GLY A 260
ALA A 287
ASN A 396
SER A 170
GLY A 167
 None
 1.27A 2vmyA-4jb6A:
undetectable		 2vmyA-4jb6A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DVAD47_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 4jb6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Pseudomonas
aeruginosa) 		4 / 4 GLY A 167
GLY A 190
GLY A 106
GLY A 189
 None
 0.65A 3bogD-4jb6A:
undetectable		 3bogD-4jb6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HUO_B_PNNB301_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 4jb6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 190
GLY A 237
SER A 236
GLY A 235
ASP A 234
 None
 0.95A 3huoB-4jb6A:
undetectable		 3huoB-4jb6A:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ID6_C_SAMC301_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 4jb6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 167
THR A 162
SER A 236
ALA A 351
ILE A 171
 None
 1.13A 3id6C-4jb6A:
undetectable		 3id6C-4jb6A:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_D_TFPD202_1
(PROTEIN S100-A4)		 4jb6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Pseudomonas
aeruginosa) 		5 / 11 GLU A 192
LEU A 343
SER A 107
PHE A  57
ASP A  72
 None
 1.50A 3ko0C-4jb6A:
undetectable
3ko0D-4jb6A:
undetectable
3ko0E-4jb6A:
undetectable
3ko0F-4jb6A:
undetectable		 3ko0C-4jb6A:
13.78
3ko0D-4jb6A:
13.78
3ko0E-4jb6A:
13.78
3ko0F-4jb6A:
13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LOQ_A_ACTA278_0
(UNIVERSAL STRESS
PROTEIN)		 4jb6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Pseudomonas
aeruginosa) 		3 / 3 SER A  82
GLY A  78
SER A 144
 None
 0.63A 3loqA-4jb6A:
undetectable		 3loqA-4jb6A:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LOQ_A_ACTA278_0
(UNIVERSAL STRESS
PROTEIN)		 4jb6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Pseudomonas
aeruginosa) 		3 / 3 SER A 334
GLY A 305
SER A 220
 None
 0.58A 3loqA-4jb6A:
undetectable		 3loqA-4jb6A:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_C_P77C203_1
(PROTEIN S100-A4)		 4jb6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Pseudomonas
aeruginosa) 		5 / 10 ASP A  72
SER A 107
GLU A 192
LEU A 342
ASP A 234
 None
 1.48A 3m0wC-4jb6A:
undetectable
3m0wD-4jb6A:
0.0
3m0wE-4jb6A:
undetectable
3m0wF-4jb6A:
0.0		 3m0wC-4jb6A:
13.52
3m0wD-4jb6A:
13.52
3m0wE-4jb6A:
13.52
3m0wF-4jb6A:
13.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_D_P77D203_1
(PROTEIN S100-A4)		 4jb6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Pseudomonas
aeruginosa) 		5 / 10 SER A 107
GLU A 192
LEU A 342
ASP A 234
ASP A  72
 None
 1.50A 3m0wA-4jb6A:
0.0
3m0wB-4jb6A:
0.0
3m0wC-4jb6A:
undetectable
3m0wD-4jb6A:
0.0		 3m0wA-4jb6A:
13.52
3m0wB-4jb6A:
13.52
3m0wC-4jb6A:
13.52
3m0wD-4jb6A:
13.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RC0_A_SAMA484_0
(N-LYSINE
METHYLTRANSFERASE
SETD6)		 4jb6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Pseudomonas
aeruginosa) 		5 / 11 VAL A  86
ALA A  85
GLY A  10
ALA A 174
LEU A 151
 None
 1.20A 3rc0A-4jb6A:
undetectable		 3rc0A-4jb6A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUK_B_AERB601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 4jb6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Pseudomonas
aeruginosa) 		5 / 12 ALA A 208
PHE A 230
ILE A 109
LEU A 343
GLY A 202
 None
 0.96A 3rukB-4jb6A:
undetectable		 3rukB-4jb6A:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SXJ_A_SAMA258_0
(PUTATIVE
METHYLTRANSFERASE)		 4jb6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 190
GLY A 344
LEU A 160
SER A 104
ALA A 348
 None
 1.04A 3sxjA-4jb6A:
undetectable		 3sxjA-4jb6A:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SXJ_B_SAMB258_0
(PUTATIVE
METHYLTRANSFERASE)		 4jb6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 190
GLY A 344
LEU A 160
SER A 104
ALA A 348
 None
 1.04A 3sxjB-4jb6A:
undetectable		 3sxjB-4jb6A:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJW_A_SRYA2001_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 4jb6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Pseudomonas
aeruginosa) 		5 / 12 THR A 166
LEU A 160
ALA A 188
SER A 104
TYR A 158
 None
 1.47A 4ejwA-4jb6A:
undetectable		 4ejwA-4jb6A:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G24_A_ACAA1004_1
(PENTATRICOPEPTIDE
REPEAT-CONTAINING
PROTEIN AT2G32230,
MITOCHONDRIAL)		 4jb6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Pseudomonas
aeruginosa) 		4 / 6 ALA A 351
LEU A 407
VAL A 408
GLU A 257
 None
 1.00A 4g24A-4jb6A:
undetectable		 4g24A-4jb6A:
21.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LS7_A_1X9A504_1
(3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2)		 4jb6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Pseudomonas
aeruginosa) 		10 / 12 GLY A 108
ALA A 163
GLU A 192
PHE A 203
HIS A 304
THR A 306
HIS A 341
LEU A 343
GLY A 399
PHE A 400
 None
 0.38A 4ls7A-4jb6A:
71.2		 4ls7A-4jb6A:
52.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LS7_A_1X9A504_1
(3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2)		 4jb6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 344
PHE A 203
THR A 308
GLY A 399
PHE A 400
 None
 0.83A 4ls7A-4jb6A:
71.2		 4ls7A-4jb6A:
52.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LS7_B_1X9B503_1
(3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2)		 4jb6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Pseudomonas
aeruginosa) 		8 / 12 ALA A 163
PHE A 203
HIS A 304
THR A 306
HIS A 341
LEU A 343
GLY A 399
PHE A 400
 None
 0.39A 4ls7A-4jb6A:
71.2
4ls7B-4jb6A:
70.8		 4ls7A-4jb6A:
52.90
4ls7B-4jb6A:
52.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LS7_B_1X9B503_1
(3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2)		 4jb6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Pseudomonas
aeruginosa) 		6 / 12 ILE A 109
ALA A 163
HIS A 304
THR A 306
HIS A 341
GLY A 399
 None
 0.63A 4ls7A-4jb6A:
71.2
4ls7B-4jb6A:
70.8		 4ls7A-4jb6A:
52.90
4ls7B-4jb6A:
52.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_B_AERB601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 4jb6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Pseudomonas
aeruginosa) 		5 / 12 LEU A 232
ALA A 208
PHE A 230
ILE A 109
LEU A 343
 None
 0.99A 4nkvB-4jb6A:
undetectable		 4nkvB-4jb6A:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_A_BQ1A1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)		 4jb6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Pseudomonas
aeruginosa) 		3 / 3 GLU A 257
ALA A 256
PHE A 412
 None
 0.61A 4v1fA-4jb6A:
undetectable		 4v1fA-4jb6A:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_C_BQ1C1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)		 4jb6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Pseudomonas
aeruginosa) 		3 / 3 GLU A 257
ALA A 256
PHE A 412
 None
 0.61A 4v1fC-4jb6A:
undetectable		 4v1fC-4jb6A:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z7F_B_FOLB201_0
(FOLATE ECF
TRANSPORTER)		 4jb6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Pseudomonas
aeruginosa) 		5 / 12 LYS A 285
ASP A 266
ALA A 317
PHE A 398
THR A 406
 None
 1.35A 4z7fB-4jb6A:
0.0		 4z7fB-4jb6A:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CPR_B_SAMB402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 4jb6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Pseudomonas
aeruginosa) 		5 / 12 GLY A  12
ALA A  85
SER A 191
PHE A  57
GLU A  61
 None
 1.49A 5cprB-4jb6A:
undetectable		 5cprB-4jb6A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E3I_A_HISA502_0
(HISTIDINE--TRNA
LIGASE)		 4jb6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Pseudomonas
aeruginosa) 		5 / 12 LEU A 209
GLY A 199
TYR A  46
GLY A 197
ALA A 195
 None
 1.11A 5e3iA-4jb6A:
undetectable		 5e3iA-4jb6A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWZ_D_010D6_0
(N-[(5-METHYLISOXAZOL
-3-YL)CARBONYL]ALANY
L-L-VALYL-N~1~-((1R,
2Z)-4-(BENZYLOXY)-4-
OXO-1-{[(3R)-2-OXOPY
RROLIDIN-3-YL]METHYL
}BUT-2-ENYL)-L-LEUCI
NAMIDE
PEDV MAIN PROTEASE)		 4jb6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Pseudomonas
aeruginosa) 		3 / 3 MET A 193
HIS A  40
GLY A  52
 None
 0.82A 5gwzB-4jb6A:
undetectable		 5gwzB-4jb6A:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4T_A_BEZA507_0
(BETA-LACTAMASE VIM-2)		 4jb6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Pseudomonas
aeruginosa) 		3 / 3 THR A 165
HIS A 304
ASN A 396
 None
 0.98A 5n4tA-4jb6A:
undetectable		 5n4tA-4jb6A:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXQ_A_NIZA808_1
(CATALASE-PEROXIDASE)		 4jb6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Pseudomonas
aeruginosa) 		4 / 8 GLY A 108
GLN A 164
LEU A 343
THR A 166
 None
 0.94A 5sxqA-4jb6A:
undetectable		 5sxqA-4jb6A:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXT_A_NIZA807_1
(CATALASE-PEROXIDASE)		 4jb6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Pseudomonas
aeruginosa) 		4 / 8 GLY A 108
GLN A 164
LEU A 343
THR A 166
 None
 0.92A 5sxtA-4jb6A:
undetectable		 5sxtA-4jb6A:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA307_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 4jb6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Pseudomonas
aeruginosa) 		4 / 4 LEU A 209
LEU A 200
SER A 233
ALA A 195
 None
 1.12A 5uunA-4jb6A:
undetectable		 5uunA-4jb6A:
23.04