SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4jb8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CPR_B_SAMB402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 4jb8 DARPIN C7_16
(synthetic
construct) 		3 / 3 HIS P  52
SER P  23
ASN P  44
 None
 0.91A 5cprB-4jb8P:
undetectable		 5cprB-4jb8P:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EYP_B_LOCB502_2
(TUBULIN BETA CHAIN)		 4jb8 DARPIN C7_16
(synthetic
construct) 		5 / 12 LEU P  84
ALA P 104
ASN P 135
ILE P  95
ALA P  87
 None
 1.30A 5eypB-4jb8P:
undetectable		 5eypB-4jb8P:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIW_D_LOCD503_2
(TUBULIN BETA CHAIN)		 4jb8 DARPIN C7_16
(synthetic
construct) 		5 / 12 LEU P  84
ALA P 104
ASN P 135
ILE P  95
ALA P  87
 None
 1.31A 5xiwD-4jb8P:
undetectable		 5xiwD-4jb8P:
20.24