SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4jb9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T9W_A_NFNA6001_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 4jb9 ANTIBODY VRC06 HEAVY
CHAIN
(Homo
sapiens) 		3 / 3 SER H   7
GLY H   8
ARG H  12
 None
 0.68A 1t9wA-4jb9H:
undetectable		 1t9wA-4jb9H:
13.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_H_ACTH614_0
(NADH DEHYDROGENASE,
PUTATIVE)		 4jb9 ANTIBODY VRC06 HEAVY
CHAIN
(Homo
sapiens) 		4 / 6 VAL H  93
TYR H  90
VAL H  37
TRP H 103
 None
 0.99A 5jwaH-4jb9H:
undetectable		 5jwaH-4jb9H:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DRZ_A_H8JA1206_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 4jb9 ANTIBODY VRC06 HEAVY
CHAIN
(Homo
sapiens) 		5 / 12 VAL H 207
THR H 205
VAL H 211
GLY H 118
VAL H 152
 None
 0.89A 6drzA-4jb9H:
undetectable		 6drzA-4jb9H:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA821_0
(GEPHYRIN)		 4jb9 ANTIBODY VRC06 HEAVY
CHAIN
(Homo
sapiens) 		3 / 3 ARG H  95
PHE H 100
GLY H 100
 None
 0.69A 6fgdA-4jb9H:
undetectable		 6fgdA-4jb9H:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FTP_B_DM2B501_1
(ALPHA-1-ANTICHYMOTRY
PSIN)		 4jb9 ANTIBODY VRC06 HEAVY
CHAIN
(Homo
sapiens) 		5 / 9 LEU H  82
SER H  17
PHE H  82
GLU H  81
LEU H  80
 None
 1.50A 6ftpA-4jb9H:
undetectable
6ftpB-4jb9H:
undetectable		 6ftpA-4jb9H:
18.45
6ftpB-4jb9H:
11.76