SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4jbb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_IMNA2001_1
(SERUM ALBUMIN)		 4jbb PUTATIVE GLUTATHIONE
S-TRANSFERASE
(Klebsiella
pneumoniae) 		6 / 10 ALA A 147
PHE A 146
ALA A 142
ARG A 139
LEU A 134
LEU A 178
 None
 1.40A 2bxqA-4jbbA:
undetectable		 2bxqA-4jbbA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GJ5_A_VD3A164_1
(BETA-LACTOGLOBULIN)		 4jbb PUTATIVE GLUTATHIONE
S-TRANSFERASE
(Klebsiella
pneumoniae) 		4 / 5 ASP A 183
LEU A 178
MET A 174
ARG A 120
 None
 1.31A 2gj5A-4jbbA:
undetectable		 2gj5A-4jbbA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TIC_A_ZMRA1002_2
(NEURAMINIDASE)		 4jbb PUTATIVE GLUTATHIONE
S-TRANSFERASE
(Klebsiella
pneumoniae) 		4 / 5 LEU A 134
ARG A 177
ARG A 120
ARG A 117
 None
FMT  A 302 (-2.9A)
None
None
 1.19A 3ticA-4jbbA:
undetectable		 3ticA-4jbbA:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 4jbb PUTATIVE GLUTATHIONE
S-TRANSFERASE
(Klebsiella
pneumoniae) 		3 / 3 ARG A 110
GLU A  77
THR A  76
 GSH  A 301 (-4.8A)
None
None
 0.89A 3v4tA-4jbbA:
undetectable		 3v4tA-4jbbA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5PHH_A_LDPA414_1
(LYSINE-SPECIFIC
DEMETHYLASE 4D)		 4jbb PUTATIVE GLUTATHIONE
S-TRANSFERASE
(Klebsiella
pneumoniae) 		4 / 6 ALA A 167
LEU A 171
TYR A 192
SER A 165
 None
 1.15A 5phhA-4jbbA:
undetectable		 5phhA-4jbbA:
26.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_B_RFPB502_2
(RIFAMPIN
MONOOXYGENASE)		 4jbb PUTATIVE GLUTATHIONE
S-TRANSFERASE
(Klebsiella
pneumoniae) 		4 / 6 GLN A 196
VAL A  24
LEU A 153
ARG A 101
 None
 1.18A 6brdB-4jbbA:
undetectable		 6brdB-4jbbA:
21.03