SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4jbd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ME7_A_MOAA600_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 4jbd PROLINE RACEMASE
(Pseudomonas
putida) 		4 / 8 ASP A 293
SER A 294
ILE A   4
GLY A  22
 None
 0.71A 1me7A-4jbdA:
undetectable		 1me7A-4jbdA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E4E_B_4PZB501_1
(CYTOCHROME P450 2E1)		 4jbd PROLINE RACEMASE
(Pseudomonas
putida) 		3 / 3 ALA A  62
THR A  16
CYH A  88
 None
None
CIT  A 401 (-3.8A)
 0.77A 3e4eB-4jbdA:
undetectable		 3e4eB-4jbdA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_D_SAMD300_0
(PUTATIVE RRNA
METHYLASE)		 4jbd PROLINE RACEMASE
(Pseudomonas
putida) 		5 / 12 GLY A 127
ILE A  93
LEU A 123
PRO A 107
THR A 130
 None
 1.14A 3eeyD-4jbdA:
undetectable		 3eeyD-4jbdA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA200_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 4jbd PROLINE RACEMASE
(Pseudomonas
putida) 		4 / 5 PRO A 135
THR A 114
VAL A 116
GLY A 117
 None
 0.77A 3elzA-4jbdA:
undetectable		 3elzA-4jbdA:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_Q_TFPQ201_1
(PROTEIN S100-A4)		 4jbd PROLINE RACEMASE
(Pseudomonas
putida) 		4 / 8 GLY A  22
PHE A  23
ILE A   7
PHE A  79
 None
 0.81A 3ko0O-4jbdA:
undetectable
3ko0Q-4jbdA:
undetectable		 3ko0O-4jbdA:
15.09
3ko0Q-4jbdA:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWW_A_ROCA1001_2
(ENDOTHIAPEPSIN)		 4jbd PROLINE RACEMASE
(Pseudomonas
putida) 		4 / 8 GLY A 160
SER A 241
ASP A 232
SER A 234
 None
 0.84A 3pwwA-4jbdA:
undetectable		 3pwwA-4jbdA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB0_A_ACTA401_0
(UNCHARACTERIZED
PROTEIN)		 4jbd PROLINE RACEMASE
(Pseudomonas
putida) 		5 / 9 ASP A 232
SER A 234
CYH A 236
GLY A 237
THR A 238
 None
None
CIT  A 401 ( 3.9A)
CIT  A 401 (-3.7A)
CIT  A 401 (-2.9A)
 0.40A 4lb0A-4jbdA:
23.4		 4lb0A-4jbdA:
29.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4jbd PROLINE RACEMASE
(Pseudomonas
putida) 		3 / 3 LEU A 182
ILE A 264
ARG A 221
 None
 0.70A 4mk4B-4jbdA:
undetectable		 4mk4B-4jbdA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WW7_A_ACTA305_0
(EKC/KEOPS COMPLEX
SUBUNIT BUD32)		 4jbd PROLINE RACEMASE
(Pseudomonas
putida) 		4 / 6 LEU A 190
LEU A 193
GLU A 194
ILE A 206
 None
 0.91A 4ww7A-4jbdA:
0.2		 4ww7A-4jbdA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 4jbd PROLINE RACEMASE
(Pseudomonas
putida) 		4 / 5 GLU A 180
THR A 183
THR A 265
HIS A  10
 None
 1.14A 5axaA-4jbdA:
undetectable		 5axaA-4jbdA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_C_ADNC502_2
(ADENOSYLHOMOCYSTEINA
SE)		 4jbd PROLINE RACEMASE
(Pseudomonas
putida) 		4 / 5 GLU A 180
THR A 183
THR A 265
HIS A  10
 None
 1.14A 5axaC-4jbdA:
undetectable		 5axaC-4jbdA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_A_X2NA590_1
(CYP51 VARIANT1)		 4jbd PROLINE RACEMASE
(Pseudomonas
putida) 		5 / 12 ALA A 230
LEU A  50
ILE A   4
PHE A  79
HIS A  90
 None
None
None
None
CIT  A 401 (-3.7A)
 1.07A 5fsaA-4jbdA:
undetectable		 5fsaA-4jbdA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VYH_A_FOLA409_0
(S PROTEIN)		 4jbd PROLINE RACEMASE
(Pseudomonas
putida) 		5 / 10 PRO A 107
GLY A 286
THR A 285
ILE A  93
ALA A 121
 None
 1.05A 5vyhA-4jbdA:
undetectable		 5vyhA-4jbdA:
21.61