SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4jbu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EA1_A_TPFA470_1
(CYTOCHROME P450
51-LIKE RV0764C)		 4jbu VIRULENCE-ASSOCIATED
V ANTIGEN
(Yersinia
pestis) 		4 / 8 TYR A 312
PHE A 308
PHE A  78
LEU A 115
 None
 1.08A 1ea1A-4jbuA:
undetectable		 1ea1A-4jbuA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_D_H4BD1290_1
(PTERIDINE REDUCTASE
1)		 4jbu VIRULENCE-ASSOCIATED
V ANTIGEN
(Yersinia
pestis) 		4 / 8 PHE A 118
LEU A  35
LEU A  79
LEU A 126
 None
 0.87A 2bfpD-4jbuA:
undetectable		 2bfpD-4jbuA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9G_A_TOPA1159_1
(DIHYDROFOLATE
REDUCTASE)		 4jbu VIRULENCE-ASSOCIATED
V ANTIGEN
(Yersinia
pestis) 		5 / 10 LEU A 253
LEU A 280
VAL A 284
SER A 235
ILE A 236
 None
 1.12A 2w9gA-4jbuA:
undetectable		 2w9gA-4jbuA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIA_B_SAMB206_0
(UPF0217 PROTEIN
MJ1640)		 4jbu VIRULENCE-ASSOCIATED
V ANTIGEN
(Yersinia
pestis) 		4 / 5 SER A 210
LEU A 198
GLY A 200
GLU A 212
 None
 1.08A 3aiaA-4jbuA:
undetectable
3aiaB-4jbuA:
undetectable		 3aiaA-4jbuA:
20.89
3aiaB-4jbuA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRB_X_TOPX300_1
(DIHYDROFOLATE
REDUCTASE)		 4jbu VIRULENCE-ASSOCIATED
V ANTIGEN
(Yersinia
pestis) 		5 / 11 LEU A 253
LEU A 280
VAL A 284
SER A 235
ILE A 236
 None
 1.09A 3frbX-4jbuA:
undetectable		 3frbX-4jbuA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRE_X_TOPX300_1
(DIHYDROFOLATE
REDUCTASE)		 4jbu VIRULENCE-ASSOCIATED
V ANTIGEN
(Yersinia
pestis) 		5 / 9 LEU A 253
LEU A 280
VAL A 284
SER A 235
ILE A 236
 None
 1.12A 3freX-4jbuA:
undetectable		 3freX-4jbuA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_A_PFLA319_1
(GLR4197 PROTEIN)		 4jbu VIRULENCE-ASSOCIATED
V ANTIGEN
(Yersinia
pestis) 		4 / 7 ILE A 186
LEU A 240
TYR A 259
ILE A 174
 None
 0.98A 3p50A-4jbuA:
undetectable		 3p50A-4jbuA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_B_PFLB319_1
(GLR4197 PROTEIN)		 4jbu VIRULENCE-ASSOCIATED
V ANTIGEN
(Yersinia
pestis) 		4 / 7 ILE A 186
LEU A 240
TYR A 259
ILE A 174
 None
 0.98A 3p50B-4jbuA:
undetectable		 3p50B-4jbuA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_C_PFLC319_1
(GLR4197 PROTEIN)		 4jbu VIRULENCE-ASSOCIATED
V ANTIGEN
(Yersinia
pestis) 		4 / 7 ILE A 186
LEU A 240
TYR A 259
ILE A 174
 None
 0.97A 3p50C-4jbuA:
undetectable		 3p50C-4jbuA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_E_PFLE319_1
(GLR4197 PROTEIN)		 4jbu VIRULENCE-ASSOCIATED
V ANTIGEN
(Yersinia
pestis) 		4 / 7 ILE A 186
LEU A 240
TYR A 259
ILE A 174
 None
 0.97A 3p50E-4jbuA:
undetectable		 3p50E-4jbuA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_C_VIVC301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 4jbu VIRULENCE-ASSOCIATED
V ANTIGEN
(Yersinia
pestis) 		5 / 12 VAL A  63
LEU A  71
ALA A 117
ILE A  44
VAL A 121
 None
 1.07A 3w67C-4jbuA:
undetectable		 3w67C-4jbuA:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_B_VIVB301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 4jbu VIRULENCE-ASSOCIATED
V ANTIGEN
(Yersinia
pestis) 		5 / 12 VAL A  63
LEU A  71
ILE A  44
LEU A 105
VAL A 121
 None
 1.10A 3w68B-4jbuA:
undetectable		 3w68B-4jbuA:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0R_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 4jbu VIRULENCE-ASSOCIATED
V ANTIGEN
(Yersinia
pestis) 		5 / 12 VAL A 284
LEU A 193
ILE A 236
ILE A 186
ILE A 184
 None
 0.82A 4y0rA-4jbuA:
undetectable		 4y0rA-4jbuA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5D_B_SAMB303_1
(METHYLTRANSFERASE)		 4jbu VIRULENCE-ASSOCIATED
V ANTIGEN
(Yersinia
pestis) 		4 / 7 PHE A 104
SER A 108
ARG A 150
ASP A 141
 None
 1.05A 5n5dB-4jbuA:
undetectable		 5n5dB-4jbuA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA307_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 4jbu VIRULENCE-ASSOCIATED
V ANTIGEN
(Yersinia
pestis) 		4 / 4 LEU A  75
LEU A  79
SER A  30
ALA A  83
 None
 1.03A 5uunA-4jbuA:
undetectable		 5uunA-4jbuA:
20.96