SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4jc5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C6Z_B_ROCB505_1
(PROTEIN (PROTEASE))		 4jc5 TRANSMEMBRANE
PROTEIN 173
(Mus
musculus) 		5 / 12 GLY A 233
GLY A 165
ILE A 164
PRO A 172
ILE A 229
 None
 0.90A 1c6zA-4jc5A:
undetectable		 1c6zA-4jc5A:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C6Z_B_ROCB505_2
(PROTEIN (PROTEASE))		 4jc5 TRANSMEMBRANE
PROTEIN 173
(Mus
musculus) 		5 / 12 GLY A 233
GLY A 165
ILE A 164
PRO A 172
ILE A 229
 None
 0.96A 1c6zB-4jc5A:
undetectable		 1c6zB-4jc5A:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FB7_A_ROCA100_1
(HIV-1 PROTEASE)		 4jc5 TRANSMEMBRANE
PROTEIN 173
(Mus
musculus) 		5 / 12 GLY A 233
GLY A 165
ILE A 164
PRO A 172
ILE A 229
 None
 0.92A 1fb7A-4jc5A:
undetectable		 1fb7A-4jc5A:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J96_A_TESA903_1
(3ALPHA-HYDROXYSTEROI
D DEHYDROGENASE TYPE
3)		 4jc5 TRANSMEMBRANE
PROTEIN 173
(Mus
musculus) 		4 / 6 TYR A 162
VAL A 312
ILE A 311
LEU A 171
 None
 1.13A 1j96A-4jc5A:
undetectable		 1j96A-4jc5A:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_A_RBFA501_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 4jc5 TRANSMEMBRANE
PROTEIN 173
(Mus
musculus) 		5 / 12 GLY A 193
SER A 194
LEU A 189
ILE A 257
LEU A 197
 None
 1.18A 1kyvA-4jc5A:
2.2
1kyvE-4jc5A:
2.2		 1kyvA-4jc5A:
20.48
1kyvE-4jc5A:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_C_RBFC503_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 4jc5 TRANSMEMBRANE
PROTEIN 173
(Mus
musculus) 		5 / 12 LEU A 197
GLY A 193
SER A 194
LEU A 189
ILE A 257
 None
 1.19A 1kyvB-4jc5A:
2.2
1kyvC-4jc5A:
2.4		 1kyvB-4jc5A:
20.48
1kyvC-4jc5A:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_D_RBFD504_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 4jc5 TRANSMEMBRANE
PROTEIN 173
(Mus
musculus) 		5 / 12 LEU A 197
GLY A 193
SER A 194
LEU A 189
ILE A 257
 None
 1.18A 1kyvC-4jc5A:
2.4
1kyvD-4jc5A:
2.3		 1kyvC-4jc5A:
20.48
1kyvD-4jc5A:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_E_RBFE505_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 4jc5 TRANSMEMBRANE
PROTEIN 173
(Mus
musculus) 		5 / 12 LEU A 197
GLY A 193
SER A 194
LEU A 189
ILE A 257
 None
 1.19A 1kyvD-4jc5A:
2.3
1kyvE-4jc5A:
2.2		 1kyvD-4jc5A:
20.48
1kyvE-4jc5A:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N49_D_RITD401_2
(PROTEASE)		 4jc5 TRANSMEMBRANE
PROTEIN 173
(Mus
musculus) 		4 / 6 GLY A 165
ILE A 164
PRO A 172
ILE A 229
 None
 0.92A 1n49D-4jc5A:
undetectable		 1n49D-4jc5A:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_E_MK1E902_3
(POL POLYPROTEIN)		 4jc5 TRANSMEMBRANE
PROTEIN 173
(Mus
musculus) 		5 / 12 GLY A 233
GLY A 165
ILE A 164
PRO A 172
ILE A 229
 None
 0.92A 2avvE-4jc5A:
undetectable		 2avvE-4jc5A:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYM_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 4jc5 TRANSMEMBRANE
PROTEIN 173
(Mus
musculus) 		5 / 12 GLY A 233
GLY A 165
ILE A 164
PRO A 172
ILE A 229
 None
 0.94A 2pymA-4jc5A:
undetectable		 2pymA-4jc5A:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYM_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 4jc5 TRANSMEMBRANE
PROTEIN 173
(Mus
musculus) 		5 / 12 GLY A 233
GLY A 165
ILE A 164
PRO A 172
ILE A 229
 None
 0.96A 2pymB-4jc5A:
undetectable		 2pymB-4jc5A:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYN_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 4jc5 TRANSMEMBRANE
PROTEIN 173
(Mus
musculus) 		5 / 12 GLY A 233
GLY A 165
ILE A 164
PRO A 172
ILE A 229
 None
 0.96A 2pynA-4jc5A:
undetectable		 2pynA-4jc5A:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 4jc5 TRANSMEMBRANE
PROTEIN 173
(Mus
musculus) 		5 / 12 GLY A 233
GLY A 165
ILE A 164
PRO A 172
ILE A 229
 None
 0.95A 2q63B-4jc5A:
undetectable		 2q63B-4jc5A:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_1
(PROTEASE RETROPEPSIN)		 4jc5 TRANSMEMBRANE
PROTEIN 173
(Mus
musculus) 		5 / 12 GLY A 233
GLY A 165
ILE A 164
PRO A 172
ILE A 229
 None
 0.92A 2q64A-4jc5A:
undetectable		 2q64A-4jc5A:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKX_B_1UNB201_1
(PROTEASE)		 4jc5 TRANSMEMBRANE
PROTEIN 173
(Mus
musculus) 		5 / 11 GLY A 233
GLY A 165
ILE A 164
PRO A 172
ILE A 229
 None
 0.94A 3ekxA-4jc5A:
undetectable		 3ekxA-4jc5A:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL1_A_DR7A100_1
(PROTEASE)		 4jc5 TRANSMEMBRANE
PROTEIN 173
(Mus
musculus) 		5 / 11 GLY A 233
GLY A 165
ILE A 164
PRO A 172
ILE A 229
 None
 0.92A 3el1A-4jc5A:
undetectable		 3el1A-4jc5A:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL1_A_DR7A100_2
(PROTEASE)		 4jc5 TRANSMEMBRANE
PROTEIN 173
(Mus
musculus) 		5 / 12 GLY A 233
GLY A 165
ILE A 164
PRO A 172
ILE A 229
 None
 0.82A 3el1B-4jc5A:
undetectable		 3el1B-4jc5A:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_D_ROCD100_1
(PROTEASE)		 4jc5 TRANSMEMBRANE
PROTEIN 173
(Mus
musculus) 		5 / 12 GLY A 233
GLY A 165
ILE A 164
PRO A 172
ILE A 229
 None
 0.95A 3ndtC-4jc5A:
undetectable		 3ndtC-4jc5A:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_D_ROCD100_2
(PROTEASE)		 4jc5 TRANSMEMBRANE
PROTEIN 173
(Mus
musculus) 		5 / 12 GLY A 233
GLY A 165
ILE A 164
PRO A 172
ILE A 229
 None
 0.95A 3ndtD-4jc5A:
undetectable		 3ndtD-4jc5A:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_A_ROCA101_1
(PROTEASE)		 4jc5 TRANSMEMBRANE
PROTEIN 173
(Mus
musculus) 		5 / 12 GLY A 233
GLY A 165
ILE A 164
PRO A 172
ILE A 229
 None
 0.90A 3nduA-4jc5A:
undetectable		 3nduA-4jc5A:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_D_ROCD100_1
(PROTEASE)		 4jc5 TRANSMEMBRANE
PROTEIN 173
(Mus
musculus) 		5 / 12 GLY A 233
GLY A 165
ILE A 164
PRO A 172
ILE A 229
 None
 0.97A 3nduC-4jc5A:
undetectable		 3nduC-4jc5A:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDW_A_RITA100_1
(PROTEASE)		 4jc5 TRANSMEMBRANE
PROTEIN 173
(Mus
musculus) 		5 / 12 GLY A 233
GLY A 165
ILE A 164
PRO A 172
ILE A 229
 None
 0.91A 3ndwA-4jc5A:
undetectable		 3ndwA-4jc5A:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDX_A_RITA100_1
(PROTEASE)		 4jc5 TRANSMEMBRANE
PROTEIN 173
(Mus
musculus) 		5 / 12 GLY A 233
GLY A 165
ILE A 164
PRO A 172
ILE A 229
 None
 0.94A 3ndxA-4jc5A:
undetectable		 3ndxA-4jc5A:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXC_A_ROCA401_1
(PROTEASE)		 4jc5 TRANSMEMBRANE
PROTEIN 173
(Mus
musculus) 		5 / 12 GLY A 233
GLY A 165
ILE A 164
PRO A 172
ILE A 229
 None
 0.91A 3oxcA-4jc5A:
undetectable		 3oxcA-4jc5A:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWR_A_ROCA401_1
(PROTEASE)		 4jc5 TRANSMEMBRANE
PROTEIN 173
(Mus
musculus) 		5 / 12 GLY A 233
GLY A 165
ILE A 164
PRO A 172
ILE A 229
 None
 0.98A 3pwrA-4jc5A:
undetectable		 3pwrA-4jc5A:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_B_ROCB801_2
(PROTEASE)		 4jc5 TRANSMEMBRANE
PROTEIN 173
(Mus
musculus) 		5 / 12 GLY A 233
GLY A 165
ILE A 164
PRO A 172
ILE A 229
 None
 0.99A 3tkgB-4jc5A:
undetectable		 3tkgB-4jc5A:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CUT_A_TYLA2971_1
(BROMODOMAIN ADJACENT
TO ZINC FINGER
DOMAIN PROTEIN 2B)		 4jc5 TRANSMEMBRANE
PROTEIN 173
(Mus
musculus) 		4 / 4 VAL A 243
VAL A 255
ASN A 182
ILE A 178
 None
 1.01A 4cutA-4jc5A:
undetectable		 4cutA-4jc5A:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJV_A_RITA500_2
(PROTEASE)		 4jc5 TRANSMEMBRANE
PROTEIN 173
(Mus
musculus) 		5 / 11 GLY A 233
GLY A 165
ILE A 164
PRO A 172
ILE A 229
 None
 0.91A 4njvB-4jc5A:
undetectable		 4njvB-4jc5A:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJV_D_RITD500_2
(PROTEASE)		 4jc5 TRANSMEMBRANE
PROTEIN 173
(Mus
musculus) 		5 / 12 GLY A 233
GLY A 165
ILE A 164
PRO A 172
ILE A 229
 None
 0.86A 4njvD-4jc5A:
undetectable		 4njvD-4jc5A:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWU_A_ACAA18_1
(WTFP-TAG,GP41)		 4jc5 TRANSMEMBRANE
PROTEIN 173
(Mus
musculus) 		5 / 12 ALA A 192
GLY A 193
SER A 194
GLU A 327
LEU A 329
 None
 1.04A 5nwuA-4jc5A:
undetectable		 5nwuA-4jc5A:
13.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XOO_A_ADNA506_1
(GLYCOSAMINOGLYCAN
XYLOSYLKINASE)		 4jc5 TRANSMEMBRANE
PROTEIN 173
(Mus
musculus) 		4 / 6 TYR A 239
LEU A 167
GLU A 259
LEU A 197
 None
 1.18A 5xooA-4jc5A:
undetectable		 5xooA-4jc5A:
16.50