SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4jcd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9A_B_BEZB307_0
(CHLOROCATECHOL
1,2-DIOXYGENASE)		 4jcd MAJOR CAPSID PROTEIN
VP1
(Human
polyomavirus
2) 		5 / 12 LEU A  87
ASP A 249
GLY A 248
TYR A 252
ARG A  84
 None
 1.47A 1s9aB-4jcdA:
undetectable		 1s9aB-4jcdA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTJ_A_THRA401_0
(ASPARTOKINASE)		 4jcd MAJOR CAPSID PROTEIN
VP1
(Human
polyomavirus
2) 		4 / 8 GLY A 243
GLU A 103
ALA A 104
ASN A 209
 None
 0.76A 2dtjA-4jcdA:
undetectable
2dtjB-4jcdA:
undetectable		 2dtjA-4jcdA:
21.45
2dtjB-4jcdA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GP0_A_NILA1_2
(MITOGEN-ACTIVATED
PROTEIN KINASE 11)		 4jcd MAJOR CAPSID PROTEIN
VP1
(Human
polyomavirus
2) 		4 / 7 ARG A  84
VAL A 287
LEU A 282
ILE A  99
 None
 0.96A 3gp0A-4jcdA:
undetectable		 3gp0A-4jcdA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I5U_B_SAMB401_1
(O-METHYLTRANSFERASE)		 4jcd MAJOR CAPSID PROTEIN
VP1
(Human
polyomavirus
2) 		3 / 3 ASP A 166
PHE A 170
SER A  71
 None
None
GOL  A 301 (-4.7A)
 0.99A 3i5uB-4jcdA:
undetectable		 3i5uB-4jcdA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		 4jcd MAJOR CAPSID PROTEIN
VP1
(Human
polyomavirus
2) 		5 / 7 THR A 210
PRO A 202
ASN A 207
GLY A 214
THR A 215
 None
None
None
EDO  A 302 (-3.7A)
EDO  A 302 (-4.0A)
 1.50A 3tajA-4jcdA:
undetectable		 3tajA-4jcdA:
24.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_A_RCXA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4jcd MAJOR CAPSID PROTEIN
VP1
(Human
polyomavirus
2) 		5 / 12 ALA A 255
VAL A 111
GLY A 113
SER A 116
LEU A 117
 None
 1.02A 5kirA-4jcdA:
undetectable		 5kirA-4jcdA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_B_RCXB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4jcd MAJOR CAPSID PROTEIN
VP1
(Human
polyomavirus
2) 		5 / 12 ALA A 255
VAL A 111
GLY A 113
SER A 116
LEU A 117
 None
 1.08A 5kirB-4jcdA:
undetectable		 5kirB-4jcdA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_C_GLYC713_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 4jcd MAJOR CAPSID PROTEIN
VP1
(Human
polyomavirus
2) 		3 / 3 GLN A 179
TYR A 160
ASN A 159
 None
 0.91A 6dwdC-4jcdA:
undetectable		 6dwdC-4jcdA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G1P_B_ACTB403_0
(ADP-RIBOSYLHYDROLASE
LIKE 2)		 4jcd MAJOR CAPSID PROTEIN
VP1
(Human
polyomavirus
2) 		3 / 3 PHE A  67
ARG A 161
GLN A 179
 None
 0.77A 6g1pB-4jcdA:
undetectable		 6g1pB-4jcdA:
22.46