SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4jci'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FK6_A_LNLA1201_1
(NON-SPECIFIC LIPID
TRANSFER PROTEIN)		 4jci PROLINE RACEMASE
(Chromohalobacter
salexigens) 		5 / 12 VAL A 167
LEU A 166
ALA A 158
ILE A 189
ILE A 206
 None
 1.02A 1fk6A-4jciA:
undetectable		 1fk6A-4jciA:
14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VN0_A_TDZA501_1
(CYTOCHROME P450 2C8)		 4jci PROLINE RACEMASE
(Chromohalobacter
salexigens) 		5 / 12 ILE A 189
PHE A 212
LEU A 211
ASN A 222
VAL A 153
 None
 0.98A 2vn0A-4jciA:
undetectable		 2vn0A-4jciA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E4E_B_4PZB501_1
(CYTOCHROME P450 2E1)		 4jci PROLINE RACEMASE
(Chromohalobacter
salexigens) 		3 / 3 ALA A  62
THR A  16
CYH A  88
 None
 0.72A 3e4eB-4jciA:
undetectable		 3e4eB-4jciA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_D_SAMD300_0
(PUTATIVE RRNA
METHYLASE)		 4jci PROLINE RACEMASE
(Chromohalobacter
salexigens) 		5 / 12 GLY A 127
ILE A  93
LEU A 123
PRO A 107
THR A 130
 None
 1.13A 3eeyD-4jciA:
undetectable		 3eeyD-4jciA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G2O_A_SAMA500_0
(PCZA361.24)		 4jci PROLINE RACEMASE
(Chromohalobacter
salexigens) 		5 / 12 ALA A  12
GLY A  13
SER A 263
GLY A 266
SER A 267
 None
 0.90A 3g2oA-4jciA:
undetectable		 3g2oA-4jciA:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_A_NIMA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 4jci PROLINE RACEMASE
(Chromohalobacter
salexigens) 		5 / 12 PHE A  38
ILE A  77
GLY A  61
ALA A  62
LEU A  18
 None
 1.12A 3n8xA-4jciA:
undetectable		 3n8xA-4jciA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LAJ_B_ACAB512_1
(HIV-1 YU2 GP120
ENVELOPE
GLYCOPROTEIN)		 4jci PROLINE RACEMASE
(Chromohalobacter
salexigens) 		4 / 6 GLY A  94
ASP A   8
PRO A  15
HIS A  56
 None
 1.26A 4lajA-4jciA:
undetectable
4lajB-4jciA:
undetectable		 4lajA-4jciA:
21.01
4lajB-4jciA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB0_A_ACTA401_0
(UNCHARACTERIZED
PROTEIN)		 4jci PROLINE RACEMASE
(Chromohalobacter
salexigens) 		6 / 9 GLY A  89
ASP A 232
SER A 234
CYH A 236
GLY A 237
THR A 238
 None
 0.77A 4lb0A-4jciA:
36.8		 4lb0A-4jciA:
29.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_B_CHDB102_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 4jci PROLINE RACEMASE
(Chromohalobacter
salexigens) 		5 / 11 GLU A 175
LEU A 174
ALA A 181
LEU A 182
TYR A 185
 None
 1.06A 4wg0B-4jciA:
undetectable
4wg0C-4jciA:
undetectable
4wg0D-4jciA:
undetectable		 4wg0B-4jciA:
4.71
4wg0C-4jciA:
4.71
4wg0D-4jciA:
4.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_E_CHDE104_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 4jci PROLINE RACEMASE
(Chromohalobacter
salexigens) 		5 / 11 ALA A 181
LEU A 182
TYR A 185
GLU A 175
LEU A 174
 None
 0.96A 4wg0C-4jciA:
undetectable
4wg0D-4jciA:
undetectable
4wg0E-4jciA:
undetectable		 4wg0C-4jciA:
4.71
4wg0D-4jciA:
4.71
4wg0E-4jciA:
4.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_G_CHDG103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 4jci PROLINE RACEMASE
(Chromohalobacter
salexigens) 		5 / 11 ALA A 181
LEU A 182
TYR A 185
GLU A 175
LEU A 174
 None
 0.98A 4wg0E-4jciA:
undetectable
4wg0F-4jciA:
undetectable
4wg0G-4jciA:
undetectable		 4wg0E-4jciA:
4.71
4wg0F-4jciA:
4.71
4wg0G-4jciA:
4.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WQ5_B_ACTB404_0
(TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE)		 4jci PROLINE RACEMASE
(Chromohalobacter
salexigens) 		3 / 3 TYR A  -3
ARG A   3
LYS A  -3
 None
 1.41A 4wq5B-4jciA:
undetectable		 4wq5B-4jciA:
25.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_A_ROCA101_1
(PROTEASE PR5-SQV)		 4jci PROLINE RACEMASE
(Chromohalobacter
salexigens) 		5 / 9 ALA A 294
ASP A 293
ILE A   7
ILE A  49
PRO A  15
 None
 1.21A 5kr2A-4jciA:
undetectable		 5kr2A-4jciA:
15.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6APH_A_ADNA501_2
(ADENOSYLHOMOCYSTEINA
SE)		 4jci PROLINE RACEMASE
(Chromohalobacter
salexigens) 		4 / 5 GLN A 261
THR A 260
THR A 130
LEU A 244
 None
 1.22A 6aphA-4jciA:
undetectable		 6aphA-4jciA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_A_ADNA502_2
(-)		 4jci PROLINE RACEMASE
(Chromohalobacter
salexigens) 		4 / 4 GLN A 261
THR A 260
THR A 130
LEU A 244
 None
 1.17A 6f3mA-4jciA:
undetectable		 6f3mA-4jciA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_C_ADNC502_2
(-)		 4jci PROLINE RACEMASE
(Chromohalobacter
salexigens) 		4 / 4 GLN A 261
THR A 260
THR A 130
LEU A 244
 None
 1.19A 6f3mC-4jciA:
undetectable		 6f3mC-4jciA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_B_ADNB501_2
(-)		 4jci PROLINE RACEMASE
(Chromohalobacter
salexigens) 		4 / 5 GLN A 261
THR A 260
THR A 130
LEU A 244
 None
 1.24A 6gbnB-4jciA:
undetectable		 6gbnB-4jciA:
23.11