SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4jcr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DCM_X_SAMX5452_0 (UNCHARACTERIZED PROTEIN TM_1570)	4jcr	ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT (Listeria monocytogenes)	5 / 11	GLY A 85 LEU A 168 SER A 169 VAL A 170 ALA A 173	None	0.95A	3dcmX-4jcrA: undetectable	3dcmX-4jcrA: 24.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DCM_X_SAMX5452_0 (UNCHARACTERIZED PROTEIN TM_1570)	4jcr	ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT (Listeria monocytogenes)	5 / 11	GLY A 87 LEU A 168 SER A 169 VAL A 170 ALA A 173	None	0.55A	3dcmX-4jcrA: undetectable	3dcmX-4jcrA: 24.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XE5_A_OBNA1104_1 (SODIUM/POTASSIUM-TRA NSPORTING ATPASE SUBUNIT ALPHA-1)	4jcr	ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT (Listeria monocytogenes)	5 / 12	GLU A 103 GLU A 101 LEU A 98 GLY A 152 ALA A 148	None	1.13A	4xe5A-4jcrA: undetectable	4xe5A-4jcrA: 11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YF9_X_NIOX401_1 (CASEIN KINASE II SUBUNIT ALPHA')	4jcr	ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT (Listeria monocytogenes)	5 / 9	LEU A 42 VAL A 38 VAL A 24 ILE A 57 ILE A 96	None	1.18A	5yf9X-4jcrA: undetectable	5yf9X-4jcrA: 17.24

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3DCM_X_SAMX5452_0","UNCHARACTERIZED PROTEIN TM_1570","4jcr","ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT","Listeria monocytogenes",5,"GLY A  85;LEU A 168;SER A 169;VAL A 170;ALA A 173","None","0.95A","3dcmX-4jcrA:undetectable","3dcmX-4jcrA:24.40"],["3DCM_X_SAMX5452_0","UNCHARACTERIZED PROTEIN TM_1570","4jcr","ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT","Listeria monocytogenes",5,"GLY A  87;LEU A 168;SER A 169;VAL A 170;ALA A 173","None","0.55A","3dcmX-4jcrA:undetectable","3dcmX-4jcrA:24.40"],["4XE5_A_OBNA1104_1","SODIUM\/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA-1","4jcr","ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT","Listeria monocytogenes",5,"GLU A 103;GLU A 101;LEU A  98;GLY A 152;ALA A 148","None","1.13A","4xe5A-4jcrA:undetectable","4xe5A-4jcrA:11.11"],["5YF9_X_NIOX401_1","CASEIN KINASE II SUBUNIT ALPHA'","4jcr","ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT","Listeria monocytogenes",5,"LEU A  42;VAL A  38;VAL A  24;ILE A  57;ILE A  96","None","1.18A","5yf9X-4jcrA:undetectable","5yf9X-4jcrA:17.24"]]