SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4jdl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T85_A_CAMA422_0
(CYTOCHROME P450-CAM)		 4jdl ABSCISIC ACID
RECEPTOR PYL5
(Arabidopsis
thaliana) 		4 / 7 THR A 152
LEU A 154
VAL A  73
VAL A  85
 None
 1.01A 1t85A-4jdlA:
undetectable		 1t85A-4jdlA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T87_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 4jdl ABSCISIC ACID
RECEPTOR PYL5
(Arabidopsis
thaliana) 		4 / 7 THR A 152
LEU A 154
VAL A  73
VAL A  85
 None
 1.06A 1t87A-4jdlA:
undetectable		 1t87A-4jdlA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRC_A_CAMA420_0
(CYTOCHROME P450-CAM)		 4jdl ABSCISIC ACID
RECEPTOR PYL5
(Arabidopsis
thaliana) 		4 / 7 THR A 152
LEU A 154
VAL A  73
VAL A  85
 None
 1.02A 1yrcA-4jdlA:
undetectable		 1yrcA-4jdlA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_A_CAMA1420_0
(CYTOCHROME P450-CAM)		 4jdl ABSCISIC ACID
RECEPTOR PYL5
(Arabidopsis
thaliana) 		4 / 6 THR A 152
LEU A 154
VAL A  73
VAL A  85
 None
 0.98A 2feuA-4jdlA:
undetectable		 2feuA-4jdlA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_B_CAMB1421_0
(CYTOCHROME P450-CAM)		 4jdl ABSCISIC ACID
RECEPTOR PYL5
(Arabidopsis
thaliana) 		4 / 7 THR A 152
LEU A 154
VAL A  73
VAL A  85
 None
 0.98A 2feuB-4jdlA:
undetectable		 2feuB-4jdlA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUI_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 4jdl ABSCISIC ACID
RECEPTOR PYL5
(Arabidopsis
thaliana) 		4 / 6 THR A 152
LEU A 154
VAL A  73
VAL A  85
 None
 1.07A 2zuiA-4jdlA:
undetectable		 2zuiA-4jdlA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWU_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 4jdl ABSCISIC ACID
RECEPTOR PYL5
(Arabidopsis
thaliana) 		4 / 7 THR A 152
LEU A 154
VAL A  73
VAL A  85
 None
 1.03A 2zwuA-4jdlA:
undetectable		 2zwuA-4jdlA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L63_A_CAMA440_0
(CAMPHOR
5-MONOOXYGENASE)		 4jdl ABSCISIC ACID
RECEPTOR PYL5
(Arabidopsis
thaliana) 		4 / 7 THR A 152
LEU A 154
VAL A  73
VAL A  85
 None
 0.93A 3l63A-4jdlA:
undetectable		 3l63A-4jdlA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4jdl ABSCISIC ACID
RECEPTOR PYL5
(Arabidopsis
thaliana) 		4 / 7 THR A 152
LEU A 154
VAL A  73
VAL A  85
 None
 0.96A 3wrhA-4jdlA:
undetectable		 3wrhA-4jdlA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4jdl ABSCISIC ACID
RECEPTOR PYL5
(Arabidopsis
thaliana) 		4 / 7 THR A 152
LEU A 154
VAL A  73
VAL A  85
 None
 1.00A 3wrjA-4jdlA:
undetectable		 3wrjA-4jdlA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4jdl ABSCISIC ACID
RECEPTOR PYL5
(Arabidopsis
thaliana) 		4 / 7 THR A 152
LEU A 154
VAL A  73
VAL A  85
 None
 0.96A 3wrlA-4jdlA:
undetectable		 3wrlA-4jdlA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 4jdl ABSCISIC ACID
RECEPTOR PYL5
(Arabidopsis
thaliana) 		4 / 7 THR A 152
LEU A 154
VAL A  73
VAL A  85
 None
 0.98A 3wrlE-4jdlA:
undetectable		 3wrlE-4jdlA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4jdl ABSCISIC ACID
RECEPTOR PYL5
(Arabidopsis
thaliana) 		4 / 7 THR A 152
LEU A 154
VAL A  73
VAL A  85
 None
 0.98A 3wrmA-4jdlA:
undetectable		 3wrmA-4jdlA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_F_CAMF503_0
(CAMPHOR
5-MONOOXYGENASE)		 4jdl ABSCISIC ACID
RECEPTOR PYL5
(Arabidopsis
thaliana) 		4 / 7 THR A 152
LEU A 154
VAL A  73
VAL A  85
 None
 0.99A 3wrmF-4jdlA:
undetectable		 3wrmF-4jdlA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4G_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4jdl ABSCISIC ACID
RECEPTOR PYL5
(Arabidopsis
thaliana) 		4 / 7 THR A 152
LEU A 154
VAL A  73
VAL A  85
 None
 0.99A 4l4gA-4jdlA:
undetectable		 4l4gA-4jdlA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZB_C_ACTC401_0
(PROTON-GATED ION
CHANNEL)		 4jdl ABSCISIC ACID
RECEPTOR PYL5
(Arabidopsis
thaliana) 		4 / 7 ILE A 134
PHE A 136
VAL A  77
GLU A 166
 None
 1.00A 4zzbC-4jdlA:
undetectable
4zzbD-4jdlA:
undetectable		 4zzbC-4jdlA:
22.71
4zzbD-4jdlA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_A_OAQA302_0
(SULFOTRANSFERASE)		 4jdl ABSCISIC ACID
RECEPTOR PYL5
(Arabidopsis
thaliana) 		5 / 12 ILE A 134
LEU A 101
VAL A  85
LEU A 196
LEU A 193
 None
 1.05A 5tiwA-4jdlA:
undetectable		 5tiwA-4jdlA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_A_ACTA406_0
(THIOREDOXIN
REDUCTASE)		 4jdl ABSCISIC ACID
RECEPTOR PYL5
(Arabidopsis
thaliana) 		3 / 3 HIS A 143
SER A 119
ARG A 107
 None
 1.01A 5u63A-4jdlA:
undetectable		 5u63A-4jdlA:
22.74