SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4jdn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Y05_A_RALA801_1 (PROSTAGLANDIN REDUCTASE 1)	4jdn	VIRULENCE PLASMID PROTEIN PGP3-D (Chlamydia trachomatis)	4 / 8	VAL A 258 VAL A 154 TYR A 221 VAL A 165	None	1.27A	2y05A-4jdnA: undetectable 2y05B-4jdnA: undetectable	2y05A-4jdnA: 17.99 2y05B-4jdnA: 17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DX5_B_MIYB1103_1 (ACRIFLAVINE RESISTANCE PROTEIN B)	4jdn	VIRULENCE PLASMID PROTEIN PGP3-D (Chlamydia trachomatis)	5 / 12	SER A 194 ASP A 168 ILE A 169 ALA A 171 VAL A 235	None	1.06A	4dx5B-4jdnA: undetectable	4dx5B-4jdnA: 10.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U8V_B_MIYB1103_1 (MULTIDRUG EFFLUX PUMP SUBUNIT ACRB)	4jdn	VIRULENCE PLASMID PROTEIN PGP3-D (Chlamydia trachomatis)	5 / 12	SER A 194 ASP A 168 ILE A 169 ALA A 171 VAL A 235	None	1.08A	4u8vB-4jdnA: undetectable	4u8vB-4jdnA: 10.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U8Y_B_MIYB1102_1 (MULTIDRUG EFFLUX PUMP SUBUNIT ACRB)	4jdn	VIRULENCE PLASMID PROTEIN PGP3-D (Chlamydia trachomatis)	5 / 12	SER A 194 ASP A 168 ILE A 169 ALA A 171 VAL A 235	None	1.08A	4u8yB-4jdnA: undetectable	4u8yB-4jdnA: 10.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U95_B_MIYB1102_1 (MULTIDRUG EFFLUX PUMP SUBUNIT ACRB)	4jdn	VIRULENCE PLASMID PROTEIN PGP3-D (Chlamydia trachomatis)	5 / 12	SER A 194 ASP A 168 ILE A 169 ALA A 171 VAL A 235	None	1.07A	4u95B-4jdnA: undetectable	4u95B-4jdnA: 10.38

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2Y05_A_RALA801_1","PROSTAGLANDIN REDUCTASE 1;PROSTAGLANDIN REDUCTASE 1","4jdn","VIRULENCE PLASMID PROTEIN PGP3-D","Chlamydia trachomatis",4,"VAL A 258;VAL A 154;TYR A 221;VAL A 165","None","1.27A","2y05A-4jdnA:undetectable;2y05B-4jdnA:undetectable","2y05A-4jdnA:17.99;2y05B-4jdnA:17.99"],["4DX5_B_MIYB1103_1","ACRIFLAVINE RESISTANCE PROTEIN B","4jdn","VIRULENCE PLASMID PROTEIN PGP3-D","Chlamydia trachomatis",5,"SER A 194;ASP A 168;ILE A 169;ALA A 171;VAL A 235","None","1.06A","4dx5B-4jdnA:undetectable","4dx5B-4jdnA:10.38"],["4U8V_B_MIYB1103_1","MULTIDRUG EFFLUX PUMP SUBUNIT ACRB","4jdn","VIRULENCE PLASMID PROTEIN PGP3-D","Chlamydia trachomatis",5,"SER A 194;ASP A 168;ILE A 169;ALA A 171;VAL A 235","None","1.08A","4u8vB-4jdnA:undetectable","4u8vB-4jdnA:10.38"],["4U8Y_B_MIYB1102_1","MULTIDRUG EFFLUX PUMP SUBUNIT ACRB","4jdn","VIRULENCE PLASMID PROTEIN PGP3-D","Chlamydia trachomatis",5,"SER A 194;ASP A 168;ILE A 169;ALA A 171;VAL A 235","None","1.08A","4u8yB-4jdnA:undetectable","4u8yB-4jdnA:10.38"],["4U95_B_MIYB1102_1","MULTIDRUG EFFLUX PUMP SUBUNIT ACRB","4jdn","VIRULENCE PLASMID PROTEIN PGP3-D","Chlamydia trachomatis",5,"SER A 194;ASP A 168;ILE A 169;ALA A 171;VAL A 235","None","1.07A","4u95B-4jdnA:undetectable","4u95B-4jdnA:10.38"]]