SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4jdu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HPV_B_478B200_2
(HIV-1 PROTEASE)		 4jdu AEROTOLERANCE-RELATE
D MEMBRANE PROTEIN
(Bacteroides
fragilis) 		5 / 9 ALA A 179
GLY A 173
ILE A 172
VAL A 135
ILE A 134
 None
 1.12A 1hpvB-4jduA:
undetectable		 1hpvB-4jduA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IEP_A_STIA201_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL)		 4jdu AEROTOLERANCE-RELATE
D MEMBRANE PROTEIN
(Bacteroides
fragilis) 		4 / 6 VAL A 225
VAL A 194
ILE A 271
ARG A 117
 None
 0.89A 1iepA-4jduA:
undetectable		 1iepA-4jduA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R30_B_SAMB501_0
(BIOTIN SYNTHASE)		 4jdu AEROTOLERANCE-RELATE
D MEMBRANE PROTEIN
(Bacteroides
fragilis) 		5 / 12 GLY A 169
HIS A 202
ASN A 201
ILE A 262
VAL A 220
 None
 1.04A 1r30B-4jduA:
undetectable		 1r30B-4jduA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S1X_A_NVPA999_1
(REVERSE
TRANSCRIPTASE)		 4jdu AEROTOLERANCE-RELATE
D MEMBRANE PROTEIN
(Bacteroides
fragilis) 		4 / 8 LEU A  96
VAL A 225
GLY A 224
LEU A 112
 None
None
None
MLY  A 116 ( 4.5A)
 1.00A 1s1xA-4jduA:
2.0		 1s1xA-4jduA:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HYY_A_STIA600_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4jdu AEROTOLERANCE-RELATE
D MEMBRANE PROTEIN
(Bacteroides
fragilis) 		4 / 6 VAL A 225
VAL A 194
ILE A 271
ARG A 117
 None
 0.90A 2hyyA-4jduA:
undetectable		 2hyyA-4jduA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KW4_A_TICA600_1
(CYTOCHROME P450 2B4)		 4jdu AEROTOLERANCE-RELATE
D MEMBRANE PROTEIN
(Bacteroides
fragilis) 		6 / 11 SER A 214
ALA A 206
GLU A 265
VAL A 195
VAL A 220
GLY A 266
 None
 1.35A 3kw4A-4jduA:
undetectable		 3kw4A-4jduA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MS9_A_STIA1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 4jdu AEROTOLERANCE-RELATE
D MEMBRANE PROTEIN
(Bacteroides
fragilis) 		4 / 6 VAL A 225
VAL A 194
ILE A 271
ARG A 117
 None
 1.02A 3ms9A-4jduA:
undetectable		 3ms9A-4jduA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_A_STIA1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 4jdu AEROTOLERANCE-RELATE
D MEMBRANE PROTEIN
(Bacteroides
fragilis) 		4 / 6 VAL A 225
VAL A 194
ILE A 271
ARG A 117
 None
 1.03A 3mssA-4jduA:
undetectable		 3mssA-4jduA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_B_STIB1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 4jdu AEROTOLERANCE-RELATE
D MEMBRANE PROTEIN
(Bacteroides
fragilis) 		4 / 7 VAL A 225
VAL A 194
ILE A 271
ARG A 117
 None
 0.87A 3mssB-4jduA:
undetectable		 3mssB-4jduA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_C_STIC1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 4jdu AEROTOLERANCE-RELATE
D MEMBRANE PROTEIN
(Bacteroides
fragilis) 		4 / 6 VAL A 225
VAL A 194
ILE A 271
ARG A 117
 None
 1.03A 3mssC-4jduA:
undetectable		 3mssC-4jduA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V5W_A_8PRA701_2
(G-PROTEIN COUPLED
RECEPTOR KINASE 2)		 4jdu AEROTOLERANCE-RELATE
D MEMBRANE PROTEIN
(Bacteroides
fragilis) 		3 / 3 LEU A 144
MET A  93
ASP A 129
 None
 0.80A 3v5wA-4jduA:
undetectable		 3v5wA-4jduA:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTA_B_ADNB401_1
(APH(2'')-ID)		 4jdu AEROTOLERANCE-RELATE
D MEMBRANE PROTEIN
(Bacteroides
fragilis) 		4 / 8 SER A 110
ILE A  98
LEU A  96
ILE A 160
 None
None
None
MLY  A 116 ( 4.2A)
 0.82A 4dtaB-4jduA:
undetectable		 4dtaB-4jduA:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KIC_B_SAMB401_0
(METHYLTRANSFERASE
MPPJ)		 4jdu AEROTOLERANCE-RELATE
D MEMBRANE PROTEIN
(Bacteroides
fragilis) 		5 / 12 ILE A 283
GLY A 268
ILE A 193
ALA A 192
ALA A 210
 None
 1.08A 4kicB-4jduA:
undetectable		 4kicB-4jduA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_A_MXMA606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4jdu AEROTOLERANCE-RELATE
D MEMBRANE PROTEIN
(Bacteroides
fragilis) 		5 / 12 LEU A 118
ILE A  94
LEU A  96
MET A 258
LEU A 223
 None
 1.41A 4m11A-4jduA:
undetectable		 4m11A-4jduA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QGI_A_ROCA101_2
(PROTEASE)		 4jdu AEROTOLERANCE-RELATE
D MEMBRANE PROTEIN
(Bacteroides
fragilis) 		5 / 11 LEU A 223
ALA A 115
ILE A 160
VAL A 194
ILE A 196
 None
MLY  A 116 ( 3.1A)
MLY  A 116 ( 4.2A)
None
None
 0.96A 4qgiB-4jduA:
undetectable		 4qgiB-4jduA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_A_DAHA60_1
(PUTATIVE CYTOCHROME
C)		 4jdu AEROTOLERANCE-RELATE
D MEMBRANE PROTEIN
(Bacteroides
fragilis) 		4 / 6 MET A 133
ASN A 221
VAL A 195
LEU A  96
 None
 1.40A 5xdhA-4jduA:
undetectable
5xdhC-4jduA:
undetectable		 5xdhA-4jduA:
17.79
5xdhC-4jduA:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_D_DAHD123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 4jdu AEROTOLERANCE-RELATE
D MEMBRANE PROTEIN
(Bacteroides
fragilis) 		5 / 10 ASP A 129
GLY A 132
ILE A  94
ILE A 283
ILE A 287
 None
 0.79A 6ebpD-4jduA:
undetectable		 6ebpD-4jduA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_A_DAHA123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 4jdu AEROTOLERANCE-RELATE
D MEMBRANE PROTEIN
(Bacteroides
fragilis) 		5 / 11 ASP A 129
GLY A 132
ILE A  94
ILE A 283
ILE A 287
 None
 0.81A 6ebzA-4jduA:
undetectable		 6ebzA-4jduA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_B_DAHB123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 4jdu AEROTOLERANCE-RELATE
D MEMBRANE PROTEIN
(Bacteroides
fragilis) 		5 / 11 ASP A 129
GLY A 132
ILE A  94
ILE A 283
ILE A 287
 None
 0.81A 6ebzB-4jduA:
undetectable		 6ebzB-4jduA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_C_DAHC123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 4jdu AEROTOLERANCE-RELATE
D MEMBRANE PROTEIN
(Bacteroides
fragilis) 		5 / 11 ASP A 129
GLY A 132
ILE A  94
ILE A 283
ILE A 287
 None
 0.80A 6ebzC-4jduA:
undetectable		 6ebzC-4jduA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_D_DAHD123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 4jdu AEROTOLERANCE-RELATE
D MEMBRANE PROTEIN
(Bacteroides
fragilis) 		5 / 11 ASP A 129
GLY A 132
ILE A  94
ILE A 283
ILE A 287
 None
 0.77A 6ebzD-4jduA:
undetectable		 6ebzD-4jduA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GP2_A_DAHA126_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
BETA CHAIN)		 4jdu AEROTOLERANCE-RELATE
D MEMBRANE PROTEIN
(Bacteroides
fragilis) 		5 / 11 ASP A 129
GLY A 132
ILE A  94
ILE A 283
ILE A 287
 None
 0.85A 6gp2A-4jduA:
undetectable		 6gp2A-4jduA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GP2_B_DAHB126_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
BETA CHAIN)		 4jdu AEROTOLERANCE-RELATE
D MEMBRANE PROTEIN
(Bacteroides
fragilis) 		5 / 11 ASP A 129
GLY A 132
ILE A  94
ILE A 283
ILE A 287
 None
 0.85A 6gp2B-4jduA:
undetectable		 6gp2B-4jduA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HQB_A_PQNA2001_0
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 4jdu AEROTOLERANCE-RELATE
D MEMBRANE PROTEIN
(Bacteroides
fragilis) 		5 / 10 SER A 216
GLY A 217
ALA A 192
GLY A 266
LEU A 112
 None
None
None
None
MLY  A 116 ( 4.5A)
 1.39A 6hqbA-4jduA:
undetectable
6hqbJ-4jduA:
undetectable		 6hqbA-4jduA:
18.14
6hqbJ-4jduA:
10.29